Subplasmalemmal Ca2+ measurements in mouse pancreatic beta cells support the existence of an amplifying effect of glucose on insulin secretion

Diabetologia

Volumn 53, Issue 9, 2010, Pages 1947-1957

  Ravier, M A ^a   Cheng Xue, R ^a   Palmer, A E ^b   Henquin, J C ^a   Gilon, P ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Amplifying pathway; Beta cell; Cytosolic calcium; Insulin secretion; Islets; Plasma membrane; Stimulus secretion coupling; Total internal reflection fluorescence microscopy

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; CELL PROTEIN; DESIGN 3 WITH CIRCULAR PERMUTED VENUS; GLUCOSE; INSULIN; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL; CALCIUM;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROSCOPY; GENE CLUSTER; INSULIN RELEASE; MOUSE; NONHUMAN; OSCILLATION; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; SENSITIVITY ANALYSIS; STIMULUS SECRETION COUPLING; ANIMAL; CELL CULTURE; CONFOCAL MICROSCOPY; DRUG EFFECTS; FEMALE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; METABOLISM; SECRETION (PROCESS);

ANIMALS; CALCIUM; CELLS, CULTURED; FEMALE; GLUCOSE; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN-SECRETING CELLS; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; IN VITRO TECHNIQUES;

EID: 77955558966     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1775-z     Document Type: Article

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