Dietary supplementation with apple juice concentrate alleviates the compensatory increase in glutathione synthase transcription and activity that accompanies dietary- and genetically-induced oxidative stress

Journal of Nutrition, Health and Aging

Volumn 8, Issue 6, 2004, Pages 492-496

  Tchantchou, F ^a   Graves, M ^a,b   Ortiz, D ^a   Rogers, E ^a   Shea, T B ^a,b  

^a UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

^b University of Massachusetts Lowell   (United States)

Author keywords

Alzheimer's disease; Antioxidants; Apolipoprotein E; Apple juice; Folate; Glutathione synthase; Oxidative stress; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; APOLIPOPROTEIN E; FOLIC ACID; GLUTATHIONE SYNTHASE; IRON;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APPLE JUICE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ELECTROPHORESIS; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HEREDITY; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE;

ANIMALIA; MALUS X DOMESTICA; MUS MUSCULUS;

EID: 8344242127     PISSN: 12797707     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. Berr C (2002) Oxidative stress and cognitive impairment in the elderly. J Nutr Health Aging. 6:261-266.
2. Butterfield DA and Lauderback CM (2002) Lipid peroxidation and protein oxidation in Alzheimer's disease: potential causes and consequences involving amyloid-beta peptide-associated free radical oxidative stress. Free Rad Biol Med 32:1050-1060.
3. Floyd RA and Hensley K (2002) Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases. Neurobiol Aging. 23:795-807.
4. Perry G, Cash AD, Smith MA (2002a) Alzheimer Disease and Oxidative Stress. J Biomed Biotechnol. 2:120-123.
5. Perry G, Nunomura A, Hirai K, Zhu X, Prez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A and Smith MA (2002b) Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med. 33:1475-1479.
6. Herrmann N (2002) Cognitive pharmacotherapy of Alzheimer's disease and other dementias. Can J Psychiatry. 47:715-722.
7. Klatte ET, Scharre DW, Nagaraja HN, Davis RA and Beversdorf DQ. (2003) Combination therapy of donepezil and vitamin E in Alzheimer disease. Alzheimer Dis Assoc Disord. 17:113-116.
8. Lalonde R, Joyal CC and Botez MI (1993) Effects of folic acid and folinic acid on cognitive and motor behaviors in 20-month-old rats. Pharmacol Biochem Behav. 44:703-707.
9. Luchsinger JA, Tang MX, Shea S and Mayeux R. (2003) Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol. 60:203-208.
10. Martin A (2003) Antioxidant vitamins E and C and risk of Alzheimer's disease. Nutr Rev. 61:69-73.
11. Mattson MM and Shea TB (2002) Folate and Homocysteine in Neural Plasticity and Neurodegenerative Disorders. Trends in Neurosciences 26:137-146.
12. Shea TB and Rogers E (2002a) Homocysteine as a risk factor for Alzheimer's disease. New Eng J Med 346; 2007
13. Shea TB, Lyons-Wieler J and Rogers E (2002a) Homocysteine, folate deprivation and Alzheimer's disease. J Alz Dis 4:261-268
14. Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB and Bickford PC (2002) Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines. J Neurosci. 22:6114-6120.
15. O'Donnell E and Lynch MA (1998) Dietary antioxidant supplementation reverses age-related neuronal changes. Neurobiol Aging. 19:461-467.
16. Joseph JA, Denisova NA, Bielinski D, Fisher DR and Shukitt-Hale B (2000) Oxidative stress protection and vulnerability in aging: putative nutritional implications for intervention. Mech Ageing Dev. 116:141-153.
17. Richardson JS (1999) Neuroprotective agents. Phys Med Rehabil Clin N Am. 10:447-461.
18. Rai SS, Shovlin C and Wesnes KA (1991) A double-blind placebo controlled study of Ginkgo biloba extract ("tanakan") in elderly outpatients with mild to moderate memory impairment. Curr Med Res Opin 12:350-355.
19. Kleijnen J and Knipschild P (1992a) Ginkgo biloba. Lancet 340:1136-1139.
20. Kleijnen J and Knipschild P (1992b) Ginkgo biloba for cerebral insufficiency. Br J Clin Pharmacol 34:352-358.
21. Kanowski S, Herrmann WM, Stephan K, Wierich W and Horr R (1996) Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Pharma-copsychiatry 29:47-56.
22. Joseph JA, Shukitt-Hale B, Denisova NA, Prior RL, Cao G, Martin A, Taglialatela G, and Bickford PC (1998) Long-Term Dietary Strawberry, Spinach, or Vitamin E Supplementation Retards the Onset of Age-Related Neuronal Signal-Transduction and Cognitive Behavioral Deficits J. Neurosci. 18: 8047-8055.
23. Smith MA, Petot GJ and Perry G. (1999) Diet and Oxidative Stress: A Novel Synthesis of Epidemiological Data on Alzheimer's Disease. J Alzheimers Dis.: 203-206.
24. Joseph JA, Shukitt-Hale B, Denisova NA, Prior RL, Cao G, Martin A, Taglialatela G, and Bickford PC (1998) Long-Term Dietary Strawberry, Spinach, or Vitamin E Supplementation Retards the Onset of Age-Related Neuronal Signal-Transduction and Cognitive Behavioral Deficits J. Neurosci. 18: 8047-8055.
25. Joseph JA, Shukitt-Hale B, Denisova NA, Bielinski D, Martin A, McEwen JJ, and Bickford PC (1999) Reversals of Age-Related Declines in Neuronal Signal Transduction, Cognitive, and Motor Behavioral Deficits with Blueberry, Spinach, or Strawberry Dietary Supplementation J. Neurosci. 19: 8114-8121
26. Rogers, EJ, Mihalick S, Ortiz D and Shea TB (2004) Apple juice prevents oxidative stress and impaired cognitive performance caused by genetic and dietary deficiencies in mice. J Nutr Health Aging 8:92-97.
27. Ramassamy C., Averill D, Beffert L., Throux L., Lussier-Cacan S., Cohn J.S., Christen Y., Schoofs J. and Davignon J. (1999) Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype. Free Rad Biol Med 27, 544-553.
28. Huang GS, Yang SM, Hong MY, Yang PC and Liu YC (2000) Differential gene expression of livers from ApoE deficient mice. Life Sci. 68:19-28.
29. Ramassamy C, Averill D, Beffert U, Theroux L, Lussier-Cacan S, Cohn JS, Christen Y, Schoofs A, Davignon J and Poirier J (2000) Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain. Neurobiol Dis. 2000 Feb;7(1):23-37.
30. Ramassamy C., Krzywkowski P, Averill D, Lussier-Cacan S., Throux L., Christen Y., Sch Davignon J and Poirier J (2002) Impact of apolipoprotein E deficiency on oxidative insults and antioxidant levels in the brain. Mol Brain Res 86: 76-83
31. Shea TB, Rogers E, Ortiz D and Sheu M-S (2002b) Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue. Free Rad Biol Med 33:1115-1120.
32. Shea, TB, Rogers E, Ashline D, Ortiz D, Duarte N, Wilson TA, Nicolosi RJ and Sheu M-H (2002c) Vitamin E deficiency does not induce compensatory antioxidant increases in central nervous system tissue of apolipoprotein E-deficient mice. J Alz Dis 4: 1-6.
33. Veinbergs I, Mallory M, Sagara Y and Masliah E (2000) Vitamin E supplementation prevents spatial learning deficits and dendritic alterations in aged apolipoprotein E-deficient mice. Eur J Neurosci. (12):4541-6.
34. Leontowicz H, Gorinstein S, Lojek A, Leontowicz M, Ci;z M, Soliva-Fortuny R, Park YS, Jung ST, Trakhtenberg S and Martin-Belloso O. (2002) Comparative content of some bioactive compounds in apples, peaches and pears and their influence on lipids and antioxidant capacity in rats. J Nutr Biochem. 13:603-610.
35. van der Sluis AA, Dekker M, Verkerk R and Jongen WM. (2000) An improved, rapid in vitro method to measure antioxidant activity. Application On selected flavonoids and apple juice. J Agric Food Chem. 48:4116-4122.
36. Wolfe KL and Liu RH. (2003) Apple peels as a value-added food ingredient. J Agric Food Chem 51:1676-1683.
37. Wolfe K, Wu X and Liu RH. (2003) Antioxidant activity of apple peels. J Agric Food Chem. 51:609-614.
38. Ortiz D and Shea TB (2004) Apple juice prevents oxidative stress induced by amyloid-beta in culture. J Alz Dis 6: 27-30.
39. Shea TB and Rogers E (2002b) Folate quenches oxidative damage in brains of apolipoprotein E-deficient mice: augmentation by vitamin E. Mol Brain Res: 108:1-6.
40. Sung S, Yao Y, Uryu K, Yang H, Lee VM, Trojanowski JQ and Pratico D (2004) Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease. FASEB J. 18:323-325.
41. Cruz R, Almaguer Melian W and Bergado Rosado JA (2003) Glutathione in cognitive function and neurodegeneration. Rev Neurol. 36:877-886.
42. Tchantchou F, Graves M, Ashline D, Morin A, Pimenta A, Ortiz D, Rogers E and Shea TB (2004) Increased transcription and activity of glutathione synthase in response to deficiencies in folate, vitamin E and apolipoprotein E. J Neurosci Res: 75:508-155.
43. Pratico, D.; Rokach, J. and Tangirala, R. K. (1999) Brains of aged apoliprotein E-deficient mice have increased levels of F2-isoprostanes, in vivo markers of lipid peroxidation. J. Neurochem. 73:736-741.
44. Spector A, Huang RR, Wang GM, Schmidt C, Yan GZ and Chifflet S (1987) Does elevated glutathione protect the cell from H2O2 insult? Exp Eye Res. 45:453-465.
45. Luchsinger JA, Tang MX, Shea S and Mayeux R. (2003) Antioxidant vitamin intake and risk of Alzheimer disease. Arch Neurol. 60:203-208.
46. Parle M and Dhingra D (2003) Ascorbic Acid: a promising memory-enhancer in mice. J Pharmacol Sci. 93:129-135
47. Fukui K, Omoi NO, Hayasaka T, Shinnkai T, Suzuki S, Abe K and Urano S (2002) Cognitive impairment of rats caused by oxidative stress and aging, and its prevention by vitamin E. Ann N Y Acad Sci. 959:275-284.
48. Cho J, Kang JS, Long PH, Jing J, Back Y and Chung KS (2003) Antioxidant and memory enhancing effects of purple sweet potato anthocyanin and cordyceps mushroom extract. Arch Pharm Res. 26:821-825.
49. Solfrizzi V, Panza F and Capurso A. (2003) The role of diet in cognitive decline. J Neural Transm. 110:95-110.
50. Cotman CW, Head E, Muggenburg BA, Zicker S and Milgram NW (2002) Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction. Neurobiol Aging. 23:809-818.
51. O'Donnell E and Lynch MA. (1998) Dietary antioxidant supplementation reverses age-related neuronal changes. Neurobiol Aging. 19:461-467
52. Joseph JA, Denisova NA, Bielinski D, Fisher DR and Shukitt-Hale B. (2000) Oxidative stress protection and vulnerability in aging: putative nutritional implications for intervention. Mech Ageing Dev. 116:141-53.
53. Gemma C, Mesches MH, Sepesi B, Choo K, Holmes DB and Bickford PC (2002) Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar beta-adrenergic function and increases in proinflammatory cytokines. J Neurosci. 22:6114-6120.