Upgrading wet granulation monitoring from hand squeeze test to mixing torque rheometry

Saudi Pharmaceutical Journal

Volumn 20, Issue 1, 2012, Pages 9-19

  Sakr, Walid F ^a,b   Ibrahim, Mohamed A ^a,b   Alanazi, Fars K ^a,b   Sakr, Adel A ^a,b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Binder; Excipient; Pellets; Torque rheometry; Wet granulation

Indexed keywords

ALCOHOL; EXCIPIENT; HYDROXYETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; IBUPROFEN; LACTOSE; MICROCRYSTALLINE CELLULOSE; POVIDONE; SOLVENT; SORBITOL;

BINDING AFFINITY; DRUG CAPSULE; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG GRANULATION; DRUG GRANULE; DRUG RELEASE; DRUG SOLUBILITY; FLOW KINETICS; FLOW MEASUREMENT; FLOWMETER; HAND SQUEEZE TEST; MIXER TORQUE RHEOMETER; PARTICLE SIZE; PREDICTION; PREFORMULATION; REVIEW; SCALE UP; SHEAR STRENGTH; SPHERONIZATION; SURFACE TENSION; TABLET COMPRESSION; TABLET FRIABILITY; TABLET HARDNESS; TABLET POROSITY; TABLET SURFACE; TORQUE; VISCOSITY; WET GRANULATION;

EID: 83355173995     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsps.2011.04.007     Document Type: Review

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