Wet granulation in laboratory scale high shear mixers: Effect of binder properties

Powder Technology

Volumn 206, Issue 1-2, 2011, Pages 25-33

  Chitu, T M ^a   Oulahna, D ^a   Hemati, M ^b  

^a ECOLE DES MINES D ALBI CARMAUX   (France)

^b LABORATOIRE DE GÉNIE CHIMIQUE   (France)

Author keywords

High shear mixer granulator; Scale up; Torque curves; Viscosity; Work of adhesion

Indexed keywords

BINDER PROPERTIES; CONSISTENCY MEASUREMENT; GRANULE SIZE; GRANULE SIZE DISTRIBUTION; HIGH SHEAR MIXER GRANULATOR; HIGH SHEAR MIXERS; HIGH VISCOSITIES; IMPELLER TIP SPEED; INCREASING VISCOSITY; LABORATORY SCALE; LOW VISCOSITY; MECHANICAL TESTING MACHINES; MICROCRYSTALLINE CELLULOSE POWDER; SCALE-UP; TORQUE CURVES; TORQUE RHEOMETER; ULTRA-PURE WATER; UNIAXIAL COMPRESSION TESTS; WET GRANULATION; WET GRANULES; WORK OF ADHESION;

ADHESION; BINDERS; COMPRESSION TESTING; GRANULATORS; GROWTH KINETICS; MIXERS (MACHINERY); MIXING; TORQUE; VISCOSITY;

GRANULATION;

HYDROXYPROPYLMETHYLCELLULOSE; MICROCRYSTALLINE CELLULOSE; POVIDONE; WATER;

ADHESION; AQUEOUS SOLUTION; ARTICLE; CHEMICAL REACTION KINETICS; COMPRESSION; DRY POWDER; MECHANICAL STRESS; MIXER; PARTICLE SIZE; PROCESSING; SCALE UP; STRENGTH; TORQUE; VISCOSITY; WET GRANULATION;

EID: 78649827950     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2010.07.012     Document Type: Article

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