Study of effect of excipient source variation on rheological behavior of diltiazem HCl-HPMC wet masses using a mixer torque rheometer

International Journal of Pharmaceutics

Volumn 238, Issue 1-2, 2002, Pages 139-151

  Chatlapalli, Ramarao ^a   Rohera, Bhagwan D ^a  

^a ST JOHN'S UNIVERSITY   (United States)

Author keywords

Diltiazem HCl; Excipient source variation; Hydroxypropyl cellulose; Hydroxypropyl methylcellulose; Methocel; Mixer torque rheometer; Pharmacoat; Substrate binder interaction

Indexed keywords

2 PROPANOL; DILTIAZEM HYDROXYPROPYLMETHYLCELLULOSE CONJUGATE; DILTIAZEM METHYLCELLULOSE CONJUGATE; EXCIPIENT; HYDROXYPROPYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; METHYLCELLULOSE; UNCLASSIFIED DRUG;

ARTICLE; DRUG FORMULATION; DRUG MIXTURE; DRUG SOLUBILITY; FLOW KINETICS; FLOW MEASUREMENT; PARTICLE SIZE; POWDER; PRIORITY JOURNAL; SURFACE PROPERTY; THERMOGRAPHY;

CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHYSICAL; DILTIAZEM; DRUG COMPOUNDING; EXCIPIENTS; METHYLCELLULOSE; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POWDERS; RHEOLOGY; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED; X-RAY DIFFRACTION;

EID: 0037093664     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(02)00065-0     Document Type: Article

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