The Fbx4 tumor suppressor regulates cyclin D1 accumulation and prevents neoplastic transformation

Molecular and Cellular Biology

Volumn 31, Issue 22, 2011, Pages 4513-4523

  Vaites, Laura Pontano ^a,b   Lee, Eric K ^a,b   Lian, Zhaorui ^a,b   Barbash, Olena ^a,b   Roy, Darshan ^b   Wasik, Mariusz ^b   Klein Szanto, Andres J P ^c   Rustgi, Anil K ^a,b   Diehl, J Alan ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CASPASE 3; CELL CYCLE PROTEIN; CYCLIN D1; HISTONE H2AX; PROTEASOME; PROTEIN FBX4; PROTEIN P16; PROTEIN P19; PROTEIN P21; PROTEIN P53; PROTEIN SKP1; RAS PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BREAST CARCINOMA; CARCINOGENESIS; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIVISION; CELL NUCLEUS; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; FIBROBLAST; GENOMIC INSTABILITY; HISTIOCYTIC SARCOMA; IN VITRO STUDY; LIVER CELL CARCINOMA; LYMPHOMA; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PHENOTYPE; PRECANCER; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; REGULATORY MECHANISM;

ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; CELL NUCLEUS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYCLIN D1; DNA DAMAGE; F-BOX PROTEINS; FIBROBLASTS; GENE KNOCKOUT TECHNIQUES; MICE; MICE, TRANSGENIC; NEOPLASMS; PROTO-ONCOGENE PROTEINS P21(RAS); SKP CULLIN F-BOX PROTEIN LIGASES;

EID: 83255192193     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.05733-11     Document Type: Article

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