Mutations in Fbx4 Inhibit Dimerization of the SCFFbx4 Ligase and Contribute to Cyclin D1 Overexpression in Human Cancer

Cancer Cell

Volumn 14, Issue 1, 2008, Pages 68-78

  Barbash, Olena ^a,b   Zamfirova, Petia ^a   Lin, Douglas I ^a,b   Chen, Xiangmei ^d   Yang, Ke ^d   Nakagawa, Hiroshi ^c   Lu, Fengmin ^d   Rustgi, Anil K ^c   Diehl, J Alan ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Peking University Health Science Center ^*  (United States)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

CELLCYCLE; PROTEINS

Indexed keywords

CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN KINASE B; RAS PROTEIN; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3;

AMINO TERMINAL SEQUENCE; ARTICLE; CARCINOGENESIS; CELL CYCLE S PHASE; CELL GROWTH; CELL TRANSFORMATION; DIMERIZATION; ENZYME ACTIVITY; ENZYME INACTIVATION; ESOPHAGUS CARCINOMA; GENE DISRUPTION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

EID: 45849131324     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccr.2008.05.017     Document Type: Article

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