Acetylation of αA-crystallin in the human lens: Effects on structure and chaperone function

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1822, Issue 2, 2012, Pages 120-129

  Nagaraj, Ram H ^a   Nahomi, Rooban B ^a   Shanthakumar, Shilpa ^a   Linetsky, Mikhail ^a   Padmanabha, Smitha ^a   Pasupuleti, Nagarekha ^a   Wang, Benlian ^a   Santhoshkumar, Puttur ^b   Panda, Alok Kumar ^c   Biswas, Ashis ^c  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Missouri   (United States)

^c INDIAN INSTITUTE OF TECHNOLOGY BHUBANESWAR   (India)

Author keywords

Crystallin; Acetylation; Aging; Chaperone; Human lens; Lysine

Indexed keywords

ACETIC ANHYDRIDE; ALPHA CRYSTALLIN; CHAPERONE; GLUTAMINE; LYSINE; TRYPTOPHAN;

ACETYLATION; AMINO ACID SEQUENCE; ARTICLE; CIRCULAR DICHROISM; HUMAN; HUMAN TISSUE; HYDROPHOBICITY; IMMUNOREACTIVITY; LENS; LIGHT SCATTERING; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS; THERMOSTABILITY;

ACETIC ANHYDRIDES; ACETYLATION; ALPHA-CRYSTALLIN A CHAIN; ALPHA-CRYSTALLIN B CHAIN; CRYSTALLINS; GLUTAMINE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LENS, CRYSTALLINE; LYSINE; MIDDLE AGED; MOLECULAR CHAPERONES; MUTANT PROTEINS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS; TRYPTOPHAN;

EID: 83055187894     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2011.11.011     Document Type: Article

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