Paradoxical effects of substitution and deletion mutation of Arg56 on the structure and chaperone function of human αB-crystallin

Biochemistry

Volumn 46, Issue 5, 2007, Pages 1117-1127

  Biswas, Ashis ^a   Goshe, Jeffery ^a   Miller, Antonia ^a   Santhoshkumar, Puttur ^d   Luckey, Carol ^b   Bhat, Manjunatha B ^c   Nagaraj, Ram H ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE FUNCTIONS; MUTANTS; PARADOXICAL EFFECTS; ULTRAVIOLET CIRCULAR DICHROISM (UVCD);

BIOASSAY; ENZYMES; LIGHT SCATTERING; MUTAGENESIS; OLIGOMERS; POLYPEPTIDES; SPECTRUM ANALYSIS;

AMINO ACIDS;

ALPHA CRYSTALLIN; AMINO ACID; ARGININE; CHAPERONE; CITRATE SYNTHASE; INSULIN; MUTANT PROTEIN; PEPTIDE; PHENYLALANYLLEUCYLARGINYLALANYLPROLYLSERYLTRYPTOPHYLPHENYLALANINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DELETION MUTANT; HUMAN; HYDROPHOBICITY; LIGHT SCATTERING; MOLECULAR WEIGHT; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE;

ALPHA-CRYSTALLIN B CHAIN; AMINO ACID SUBSTITUTION; ARGININE; CITRATE (SI)-SYNTHASE; DIMERIZATION; FRAMESHIFT MUTATION; HUMANS; HYDROPHOBICITY; INSULIN; MOLECULAR CHAPERONES; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 33846809269     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061323w     Document Type: Article

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