Mutation of R116C results in highly oligomerized αA-Crystallin with modified structure and defective chaperone-like function

Biochemistry

Volumn 39, Issue 6, 2000, Pages 1420-1426

  Shroff, Nilufer P ^a   Cherian Shaw, Mary ^a   Bera, Sibes ^a   Abraham, Edathara C ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLIN;

ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CONFORMATIONAL TRANSITION; CONGENITAL CATARACT; GENE MUTATION; GENETIC LINKAGE; HUMAN; MOLECULAR CLONING; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS; THERMOSTABILITY;

ANIMALS; ARGININE; BIOPOLYMERS; CHROMATOGRAPHY, GEL; CLONING, MOLECULAR; CRYSTALLINS; CYSTEINE; HEAT; MOLECULAR CHAPERONES; MOLECULAR WEIGHT; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; SERINE; SPECTROMETRY, FLUORESCENCE;

EID: 0034673151     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991656b     Document Type: Article

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