메뉴 건너뛰기




Volumn 20, Issue 6, 2010, Pages 189-195

Cardiovascular Biology of Microsomal Prostaglandin E Synthase-1

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 2 RECEPTOR; CYCLOOXYGENASE 2; LIPOPOLYSACCHARIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E SYNTHASE 1;

EID: 83055179062     PISSN: 10501738     EISSN: 18732615     Source Type: Journal    
DOI: 10.1016/j.tcm.2011.04.002     Document Type: Review
Times cited : (33)

References (65)
  • 1
    • 18544400864 scopus 로고    scopus 로고
    • 2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes
    • 2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes. J Biol Chem 2004, 279:21929-21937.
    • (2004) J Biol Chem , vol.279 , pp. 21929-21937
    • Alvarez-Maqueda, M.1    El Bekay, R.2    Alba, G.3
  • 2
    • 56449095449 scopus 로고    scopus 로고
    • Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis
    • Babaev V.R., Chew J.D., Ding L., et al. Macrophage EP4 deficiency increases apoptosis and suppresses early atherosclerosis. Cell Metab 2008, 8:492-501.
    • (2008) Cell Metab , vol.8 , pp. 492-501
    • Babaev, V.R.1    Chew, J.D.2    Ding, L.3
  • 3
    • 78751539135 scopus 로고    scopus 로고
    • Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation
    • Brenneis C., Coste O., Altenrath K., et al. Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation. J Biol Chem 2011, 286:2331-2342.
    • (2011) J Biol Chem , vol.286 , pp. 2331-2342
    • Brenneis, C.1    Coste, O.2    Altenrath, K.3
  • 4
    • 19744380776 scopus 로고    scopus 로고
    • Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
    • Bresalier R.S., Sandler R.S., Quan H., et al. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 2005, 352:1092-1102.
    • (2005) N Engl J Med , vol.352 , pp. 1092-1102
    • Bresalier, R.S.1    Sandler, R.S.2    Quan, H.3
  • 5
    • 73649122841 scopus 로고    scopus 로고
    • Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo?. An updated meta-analysis
    • Chan C.C., Reid C.M., Aw T.J., et al. Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo?. An updated meta-analysis. J Hypertens 2009, 27:2332-2341.
    • (2009) J Hypertens , vol.27 , pp. 2332-2341
    • Chan, C.C.1    Reid, C.M.2    Aw, T.J.3
  • 6
    • 43949108882 scopus 로고    scopus 로고
    • Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis
    • Chen M., Boilard E., Nigrovic P.A., et al. Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis. Arthritis Rheum 2008, 58:1354-1365.
    • (2008) Arthritis Rheum , vol.58 , pp. 1354-1365
    • Chen, M.1    Boilard, E.2    Nigrovic, P.A.3
  • 8
    • 33646415952 scopus 로고    scopus 로고
    • Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function
    • Cheng Y., Wang M., Yu Y., et al. Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. J Clin Invest 2006, 116:1391-1399.
    • (2006) J Clin Invest , vol.116 , pp. 1391-1399
    • Cheng, Y.1    Wang, M.2    Yu, Y.3
  • 9
    • 0242584866 scopus 로고    scopus 로고
    • 2 production in the rat adjuvant-induced arthritis model
    • 2 production in the rat adjuvant-induced arthritis model. J Immunol 2003, 170:4738-4744.
    • (2003) J Immunol , vol.170 , pp. 4738-4744
    • Claveau, D.1    Sirinyan, M.2    Guay, J.3
  • 10
    • 41649119130 scopus 로고    scopus 로고
    • 2 synthase-1 deletion leads to adverse left ventricular remodeling after myocardial infarction
    • 2 synthase-1 deletion leads to adverse left ventricular remodeling after myocardial infarction. Circulation 2008, 117:1701-1710.
    • (2008) Circulation , vol.117 , pp. 1701-1710
    • Degousee, N.1    Fazel, S.2    Angoulvant, D.3
  • 11
    • 0034894058 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo
    • Dowd N.P., Scully M., Adderley S.R., et al. Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. J Clin Invest 2001, 108:585-590.
    • (2001) J Clin Invest , vol.108 , pp. 585-590
    • Dowd, N.P.1    Scully, M.2    Adderley, S.R.3
  • 12
    • 10344267004 scopus 로고    scopus 로고
    • COX-2-derived prostacyclin confers atheroprotection on female mice
    • Egan K.M., Lawson J.A., Fries S., et al. COX-2-derived prostacyclin confers atheroprotection on female mice. Science 2004, 306:1954-1957.
    • (2004) Science , vol.306 , pp. 1954-1957
    • Egan, K.M.1    Lawson, J.A.2    Fries, S.3
  • 13
    • 12844278633 scopus 로고    scopus 로고
    • Cyclooxygenases, thromboxane, and atherosclerosis: Plaque destabilization by cyclooxygenase-2 inhibition combined with thromboxane receptor antagonism
    • Egan K.M., Wang M., Fries S., et al. Cyclooxygenases, thromboxane, and atherosclerosis: Plaque destabilization by cyclooxygenase-2 inhibition combined with thromboxane receptor antagonism. Circulation 2005, 111:334-342.
    • (2005) Circulation , vol.111 , pp. 334-342
    • Egan, K.M.1    Wang, M.2    Fries, S.3
  • 14
    • 0242321826 scopus 로고    scopus 로고
    • Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis
    • Engblom D., Saha S., Engström S., et al. Microsomal prostaglandin E synthase-1 is the central switch during immune-induced pyresis. Net Neurosci 2003, 6:1137-1138.
    • (2003) Net Neurosci , vol.6 , pp. 1137-1138
    • Engblom, D.1    Saha, S.2    Engström, S.3
  • 15
    • 0035098077 scopus 로고    scopus 로고
    • 2 inhibits cAMP production and promotes platelet aggregation
    • 2 inhibits cAMP production and promotes platelet aggregation. J Clin Invest 2001, 107:603-610.
    • (2001) J Clin Invest , vol.107 , pp. 603-610
    • Fabre, J.E.1    Nguyen, M.2    Athirakul, K.3
  • 16
    • 0034616262 scopus 로고    scopus 로고
    • Human glutathione dependent prostaglandin E synthase: Gene structure and regulation
    • Forsberg L., Leeb L., Thoren S., et al. Human glutathione dependent prostaglandin E synthase: Gene structure and regulation. FEBS Lett 2000, 471:78-82.
    • (2000) FEBS Lett , vol.471 , pp. 78-82
    • Forsberg, L.1    Leeb, L.2    Thoren, S.3
  • 17
    • 34248159448 scopus 로고    scopus 로고
    • Role of microsomal prostaglandin E synthase 1 in the kidney
    • Francois H., Facemire C., Kumar A., et al. Role of microsomal prostaglandin E synthase 1 in the kidney. J Am Soc Nephrol 2007, 18:1466-1475.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1466-1475
    • Francois, H.1    Facemire, C.2    Kumar, A.3
  • 18
    • 55049100980 scopus 로고    scopus 로고
    • Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population
    • Garcia Rodriguez L.A., Tacconelli S., Patrignani P. Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population. J Am Coll Cardiol 2008, 52:1628-1636.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1628-1636
    • Garcia Rodriguez, L.A.1    Tacconelli, S.2    Patrignani, P.3
  • 20
    • 31044441042 scopus 로고    scopus 로고
    • Biological basis for the cardiovascular consequences of COX-2 inhibition: Therapeutic challenges and opportunities
    • Grosser T., Fries S., FitzGerald G.A. Biological basis for the cardiovascular consequences of COX-2 inhibition: Therapeutic challenges and opportunities. J Clin Invest 2006, 116:4-15.
    • (2006) J Clin Invest , vol.116 , pp. 4-15
    • Grosser, T.1    Fries, S.2    FitzGerald, G.A.3
  • 21
    • 77951909982 scopus 로고    scopus 로고
    • Emotion recollected in tranquility: Lessons learned from the COX-2 saga
    • Grosser T., Yu Y., FitzGerald G.A. Emotion recollected in tranquility: Lessons learned from the COX-2 saga. Annu Rev Med 2010, 61:17-33.
    • (2010) Annu Rev Med , vol.61 , pp. 17-33
    • Grosser, T.1    Yu, Y.2    FitzGerald, G.A.3
  • 22
    • 73249123772 scopus 로고    scopus 로고
    • Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells
    • Hanaka H., Pawelzik S.C., Johnsen J.I., et al. Microsomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells. Proc Natl Acad Sci USA 2009, 106:18757-18762.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 18757-18762
    • Hanaka, H.1    Pawelzik, S.C.2    Johnsen, J.I.3
  • 23
    • 79955053753 scopus 로고    scopus 로고
    • Lack of microsomal prostaglandin E synthase-1 reduces cardiac function following angiotensin II infusion
    • Harding P., Yang X.P., He Q., Lapointe M.C. Lack of microsomal prostaglandin E synthase-1 reduces cardiac function following angiotensin II infusion. Am J Physiol Heart Circ Physiol 2011, 300:H1053-H1056.
    • (2011) Am J Physiol Heart Circ Physiol , vol.300
    • Harding, P.1    Yang, X.P.2    He, Q.3    Lapointe, M.C.4
  • 24
    • 0033594963 scopus 로고    scopus 로고
    • Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target
    • Jakobsson P.J., Thoren S., Morgenstern R., Samuelsson B. Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci USA 1999, 96:7220-7225.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7220-7225
    • Jakobsson, P.J.1    Thoren, S.2    Morgenstern, R.3    Samuelsson, B.4
  • 26
    • 33751326323 scopus 로고    scopus 로고
    • Deletion of microsomal prostaglandin E synthase-1 increases sensitivity to salt loading and angiotensin II infusion
    • Jia Z., Zhang A., Zhang H., et al. Deletion of microsomal prostaglandin E synthase-1 increases sensitivity to salt loading and angiotensin II infusion. Circ Res 2006, 99:1243-1251.
    • (2006) Circ Res , vol.99 , pp. 1243-1251
    • Jia, Z.1    Zhang, A.2    Zhang, H.3
  • 27
    • 4043169152 scopus 로고    scopus 로고
    • Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin E synthase-1
    • Kamei D., Yamakawa K., Takegoshi Y., et al. Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin E synthase-1. J Biol Chem 2004, 279:33684-33695.
    • (2004) J Biol Chem , vol.279 , pp. 33684-33695
    • Kamei, D.1    Yamakawa, K.2    Takegoshi, Y.3
  • 30
    • 33646462753 scopus 로고    scopus 로고
    • Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice
    • King V.L., Trivedi D.B., Gitlin J.M., Loftin C.D. Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice. Arterioscler Thromb Vasc Biol 2006, 26:1137-1143.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1137-1143
    • King, V.L.1    Trivedi, D.B.2    Gitlin, J.M.3    Loftin, C.D.4
  • 31
    • 9644272529 scopus 로고    scopus 로고
    • Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice
    • Kobayashi T., Tahara Y., Matsumoto M., et al. Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice. J Clin Invest 2004, 114:784-794.
    • (2004) J Clin Invest , vol.114 , pp. 784-794
    • Kobayashi, T.1    Tahara, Y.2    Matsumoto, M.3
  • 32
    • 34547846004 scopus 로고    scopus 로고
    • Effect of celecoxib on restenosis after coronary angioplasty with a Taxus stent (COREA-TAXUS trial): An open-label randomised controlled study
    • Koo B.K., Kim Y.S., Park K.W., et al. Effect of celecoxib on restenosis after coronary angioplasty with a Taxus stent (COREA-TAXUS trial): An open-label randomised controlled study. Lancet 2007, 370:567-574.
    • (2007) Lancet , vol.370 , pp. 567-574
    • Koo, B.K.1    Kim, Y.S.2    Park, K.W.3
  • 33
    • 1842453964 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and inflammation in atherosclerosis
    • Linton M.F., Fazio S. Cyclooxygenase-2 and inflammation in atherosclerosis. Curr Opin Pharmacol 2004, 4:116-123.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 116-123
    • Linton, M.F.1    Fazio, S.2
  • 34
    • 33645968137 scopus 로고    scopus 로고
    • Prostaglandin E synthase: A novel drug target for inflammation and cancer
    • Murakami M., Kudo I. Prostaglandin E synthase: A novel drug target for inflammation and cancer. Curr Pharm Des 2006, 12:943-954.
    • (2006) Curr Pharm Des , vol.12 , pp. 943-954
    • Murakami, M.1    Kudo, I.2
  • 35
    • 44849085464 scopus 로고    scopus 로고
    • Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis
    • Nakanishi M., Montrose D.C., Clark P., et al. Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis. Cancer Res 2008, 68:3251-3259.
    • (2008) Cancer Res , vol.68 , pp. 3251-3259
    • Nakanishi, M.1    Montrose, D.C.2    Clark, P.3
  • 36
    • 77956523191 scopus 로고    scopus 로고
    • Identification of key residues determining species differences in inhibitor binding of microsomal prostaglandin E synthase-1
    • Pawelzik S.C., Uda N.R., Spahiu L., et al. Identification of key residues determining species differences in inhibitor binding of microsomal prostaglandin E synthase-1. J Biol Chem 2010, 285:29254-29261.
    • (2010) J Biol Chem , vol.285 , pp. 29254-29261
    • Pawelzik, S.C.1    Uda, N.R.2    Spahiu, L.3
  • 38
    • 0036308753 scopus 로고    scopus 로고
    • Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
    • Qi Z., Hao C.M., Langenbach R.I., et al. Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II. J Clin Invest 2002, 110:61-69.
    • (2002) J Clin Invest , vol.110 , pp. 61-69
    • Qi, Z.1    Hao, C.M.2    Langenbach, R.I.3
  • 39
    • 77953526527 scopus 로고    scopus 로고
    • Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: Potential drug targets in cancer
    • Radmark O., Samuelsson B. Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: Potential drug targets in cancer. J Intern Med 2010, 268:5-14.
    • (2010) J Intern Med , vol.268 , pp. 5-14
    • Radmark, O.1    Samuelsson, B.2
  • 40
    • 21844451360 scopus 로고    scopus 로고
    • COX-2-derived prostacyclin modulates vascular remodeling
    • Rudic R.D., Brinster D., Cheng Y., et al. COX-2-derived prostacyclin modulates vascular remodeling. Circ Res 2005, 96:1240-1247.
    • (2005) Circ Res , vol.96 , pp. 1240-1247
    • Rudic, R.D.1    Brinster, D.2    Cheng, Y.3
  • 41
    • 0029666024 scopus 로고    scopus 로고
    • Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms
    • Sakalihasan N., Delvenne P., Nusgens B.V., et al. Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms. J Vasc Surg 1996, 24:127-133.
    • (1996) J Vasc Surg , vol.24 , pp. 127-133
    • Sakalihasan, N.1    Delvenne, P.2    Nusgens, B.V.3
  • 43
    • 34748817976 scopus 로고    scopus 로고
    • Membrane prostaglandin E synthase-1: A novel therapeutic target
    • Samuelsson B., Morgenstern R., Jakobsson P.J. Membrane prostaglandin E synthase-1: A novel therapeutic target. Pharmacol Rev 2007, 59:207-224.
    • (2007) Pharmacol Rev , vol.59 , pp. 207-224
    • Samuelsson, B.1    Morgenstern, R.2    Jakobsson, P.J.3
  • 44
    • 12144285707 scopus 로고    scopus 로고
    • Membrane-associated PGE synthase-1 (mPGES-1) is coexpressed with both COX-1 and COX-2 in the kidney
    • Schneider A., Zhang Y., Zhang M., et al. Membrane-associated PGE synthase-1 (mPGES-1) is coexpressed with both COX-1 and COX-2 in the kidney. Kidney Int 2004, 65:1205-1213.
    • (2004) Kidney Int , vol.65 , pp. 1205-1213
    • Schneider, A.1    Zhang, Y.2    Zhang, M.3
  • 45
    • 33746068237 scopus 로고    scopus 로고
    • Is mPGES-1 a promising target for pain therapy?
    • Scholich K., Geisslinger G. Is mPGES-1 a promising target for pain therapy?. Trends Pharmacol Sci 2006, 27:399-401.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 399-401
    • Scholich, K.1    Geisslinger, G.2
  • 47
    • 20144365496 scopus 로고    scopus 로고
    • Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
    • Solomon S.D., McMurray J.J., Pfeffer M.A., et al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 2005, 352:1071-1080.
    • (2005) N Engl J Med , vol.352 , pp. 1071-1080
    • Solomon, S.D.1    McMurray, J.J.2    Pfeffer, M.A.3
  • 48
    • 42449093389 scopus 로고    scopus 로고
    • Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: The cross trial safety analysis
    • Solomon S.D., Wittes J., Finn P.V., et al. Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: The cross trial safety analysis. Circulation 2008, 117:2104-2113.
    • (2008) Circulation , vol.117 , pp. 2104-2113
    • Solomon, S.D.1    Wittes, J.2    Finn, P.V.3
  • 49
    • 78650449351 scopus 로고    scopus 로고
    • Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions
    • Tang E.H., Shimizu K., Christen T., et al. Lack of EP4 receptors on bone marrow-derived cells enhances inflammation in atherosclerotic lesions. Cardiovasc Res 2011, 89:234-243.
    • (2011) Cardiovasc Res , vol.89 , pp. 234-243
    • Tang, E.H.1    Shimizu, K.2    Christen, T.3
  • 51
    • 33747119962 scopus 로고    scopus 로고
    • Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice
    • Thomas M., Gavrila D., McCormick M.L., et al. Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. Circulation 2006, 114:404-413.
    • (2006) Circulation , vol.114 , pp. 404-413
    • Thomas, M.1    Gavrila, D.2    McCormick, M.L.3
  • 52
    • 0038266571 scopus 로고    scopus 로고
    • Human microsomal prostaglandin E synthase-1: Purification, functional characterization, and projection structure determination
    • Thoren S., Weinander R., Saha S., et al. Human microsomal prostaglandin E synthase-1: Purification, functional characterization, and projection structure determination. J Biol Chem 2003, 278:22199-22209.
    • (2003) J Biol Chem , vol.278 , pp. 22199-22209
    • Thoren, S.1    Weinander, R.2    Saha, S.3
  • 53
    • 0043261465 scopus 로고    scopus 로고
    • Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase
    • Trebino C.E., Stock J.L., Gibbons C.P., et al. Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase. Proc Natl Acad Sci USA 2003, 100:9044-9049.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9044-9049
    • Trebino, C.E.1    Stock, J.L.2    Gibbons, C.P.3
  • 54
    • 0033529170 scopus 로고    scopus 로고
    • 2 synthesis in abdominal aortic aneurysms: Implications for smooth muscle cell viability, inflammatory processes, and the expansion of abdominal aortic aneurysms
    • 2 synthesis in abdominal aortic aneurysms: Implications for smooth muscle cell viability, inflammatory processes, and the expansion of abdominal aortic aneurysms. Circulation 1999, 100:48-54.
    • (1999) Circulation , vol.100 , pp. 48-54
    • Walton, L.J.1    Franklin, I.J.2    Bayston, T.3
  • 55
    • 66149138017 scopus 로고    scopus 로고
    • Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function
    • Wang D., Patel V.V., Ricciotti E., et al. Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function. Proc Natl Acad Sci USA 2009, 106:7548-7552.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 7548-7552
    • Wang, D.1    Patel, V.V.2    Ricciotti, E.3
  • 56
    • 19944386895 scopus 로고    scopus 로고
    • Celecoxib, a selective cyclooxygenase-2 inhibitor, decreases monocyte chemoattractant protein-1 expression and neointimal hyperplasia in the rabbit atherosclerotic balloon injury model
    • Wang K., Tarakji K., Zhou Z., et al. Celecoxib, a selective cyclooxygenase-2 inhibitor, decreases monocyte chemoattractant protein-1 expression and neointimal hyperplasia in the rabbit atherosclerotic balloon injury model. J Cardiovasc Pharmacol 2005, 45:61-67.
    • (2005) J Cardiovasc Pharmacol , vol.45 , pp. 61-67
    • Wang, K.1    Tarakji, K.2    Zhou, Z.3
  • 57
    • 77953770999 scopus 로고    scopus 로고
    • Deletion of microsomal prostaglandin E synthase-1 does not alter ozone-induced airway hyper-responsiveness
    • Wang M., Cooper P.R., Jiang M., et al. Deletion of microsomal prostaglandin E synthase-1 does not alter ozone-induced airway hyper-responsiveness. J Pharmacol Exp Ther 2010, 334:63-68.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 63-68
    • Wang, M.1    Cooper, P.R.2    Jiang, M.3
  • 59
    • 40549145155 scopus 로고    scopus 로고
    • Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation
    • Wang M., Lee E., Song W., et al. Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation. Circulation 2008, 117:1302-1309.
    • (2008) Circulation , vol.117 , pp. 1302-1309
    • Wang, M.1    Lee, E.2    Song, W.3
  • 60
    • 70350011904 scopus 로고    scopus 로고
    • Comparison of microsomal prostaglandin E synthase-1 deletion and COX-2 inhibition in acute cardiac ischemia in mice
    • Wu D., Mennerich D., Arndt K., et al. Comparison of microsomal prostaglandin E synthase-1 deletion and COX-2 inhibition in acute cardiac ischemia in mice. Prostaglandins Other Lipid Mediat 2009, 90:21-25.
    • (2009) Prostaglandins Other Lipid Mediat , vol.90 , pp. 21-25
    • Wu, D.1    Mennerich, D.2    Arndt, K.3
  • 61
    • 67649435977 scopus 로고    scopus 로고
    • The effects of microsomal prostaglandin E synthase-1 deletion in acute cardiac ischemia in mice
    • Wu D., Mennerich D., Arndt K., et al. The effects of microsomal prostaglandin E synthase-1 deletion in acute cardiac ischemia in mice. Prostaglandins Leukot Essent Fatty Acids 2009, 81:31-33.
    • (2009) Prostaglandins Leukot Essent Fatty Acids , vol.81 , pp. 31-33
    • Wu, D.1    Mennerich, D.2    Arndt, K.3
  • 62
    • 58049218996 scopus 로고    scopus 로고
    • Homo-timeric structural model of human microsomal prostaglandin E synthase-1 and characterization of its substrate/inhibitor binding interactions
    • Xing L., Kurumbail R.G., Frazier R.B., et al. Homo-timeric structural model of human microsomal prostaglandin E synthase-1 and characterization of its substrate/inhibitor binding interactions. J Comput Aided Mol Des 2009, 23:13-24.
    • (2009) J Comput Aided Mol Des , vol.23 , pp. 13-24
    • Xing, L.1    Kurumbail, R.G.2    Frazier, R.B.3
  • 63
    • 53849098967 scopus 로고    scopus 로고
    • 1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation
    • 1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation. J Pharmacol Exp Ther 2008, 326:754-763.
    • (2008) J Pharmacol Exp Ther , vol.326 , pp. 754-763
    • Xu, D.1    Rowland, S.E.2    Clark, P.3
  • 64
    • 3242738304 scopus 로고    scopus 로고
    • Celecoxib, a cyclooxygenase-2 inhibitor, reduces neointimal hyperplasia through inhibition of Akt signaling
    • Yang H.M., Kim H.S., Park K.W., et al. Celecoxib, a cyclooxygenase-2 inhibitor, reduces neointimal hyperplasia through inhibition of Akt signaling. Circulation 2004, 110:301-308.
    • (2004) Circulation , vol.110 , pp. 301-308
    • Yang, H.M.1    Kim, H.S.2    Park, K.W.3
  • 65
    • 18744395794 scopus 로고    scopus 로고
    • Influence of genetic background and gender on hypertension and renal failure in COX-2-deficient mice
    • Yang T., Huang Y.G., Ye W., et al. Influence of genetic background and gender on hypertension and renal failure in COX-2-deficient mice. Am J Physiol Renal Physiol 2005, 288:F1125-F1132.
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Yang, T.1    Huang, Y.G.2    Ye, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.