-
2
-
-
1442301515
-
Cyclooxygenase enzymes: regulation and function
-
Fitzpatrick F.A. Cyclooxygenase enzymes: regulation and function. Curr Pharm Des 10 (2004) 577-588
-
(2004)
Curr Pharm Des
, vol.10
, pp. 577-588
-
-
Fitzpatrick, F.A.1
-
3
-
-
0034707105
-
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group
-
Bombardier C., Laine L., Reicin A., et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group. N Engl J Med 343 (2000) 1520-1528
-
(2000)
N Engl J Med
, vol.343
, pp. 1520-1528
-
-
Bombardier, C.1
Laine, L.2
Reicin, A.3
-
4
-
-
19744380776
-
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
-
Bresalier R.S., Sandler R.S., Quan H., et al. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 352 (2005) 1092-1102
-
(2005)
N Engl J Med
, vol.352
, pp. 1092-1102
-
-
Bresalier, R.S.1
Sandler, R.S.2
Quan, H.3
-
5
-
-
34748817976
-
Membrane prostaglandin e synthase-1: a novel therapeutic target
-
Samuelsson B., Morgenstern R., and Jakobsson P.J. Membrane prostaglandin e synthase-1: a novel therapeutic target. Pharmacol Rev 59 (2007) 207-224
-
(2007)
Pharmacol Rev
, vol.59
, pp. 207-224
-
-
Samuelsson, B.1
Morgenstern, R.2
Jakobsson, P.J.3
-
6
-
-
0242584866
-
Microsomal prostaglandin E synthase-1 is a major terminal synthase that is selectively up-regulated during cyclooxygenase-2-dependent prostaglandin E2 production in the rat adjuvant-induced arthritis model
-
Claveau D., Sirinyan M., Guay J., et al. Microsomal prostaglandin E synthase-1 is a major terminal synthase that is selectively up-regulated during cyclooxygenase-2-dependent prostaglandin E2 production in the rat adjuvant-induced arthritis model. J Immunol 170 (2003) 4738-4744
-
(2003)
J Immunol
, vol.170
, pp. 4738-4744
-
-
Claveau, D.1
Sirinyan, M.2
Guay, J.3
-
7
-
-
4043169152
-
Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1
-
Kamei D., Yamakawa K., Takegoshi Y., et al. Reduced pain hypersensitivity and inflammation in mice lacking microsomal prostaglandin e synthase-1. J Biol Chem 279 (2004) 33684-33695
-
(2004)
J Biol Chem
, vol.279
, pp. 33684-33695
-
-
Kamei, D.1
Yamakawa, K.2
Takegoshi, Y.3
-
8
-
-
33745266737
-
Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases
-
Park J.Y., Pillinger M.H., and Abramson S.B. Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases. Clin Immunol 119 (2006) 229-240
-
(2006)
Clin Immunol
, vol.119
, pp. 229-240
-
-
Park, J.Y.1
Pillinger, M.H.2
Abramson, S.B.3
-
9
-
-
0043261465
-
Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase
-
Trebino C.E., Stock J.L., Gibbons C.P., et al. Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase. Proc Natl Acad Sci USA 100 (2003) 9044-9049
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9044-9049
-
-
Trebino, C.E.1
Stock, J.L.2
Gibbons, C.P.3
-
10
-
-
33646415952
-
Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function
-
Cheng Y., Wang M., Yu Y., Lawson J., Funk C.D., and Fitzgerald G.A. Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. J Clin Invest 116 (2006) 1391-1399
-
(2006)
J Clin Invest
, vol.116
, pp. 1391-1399
-
-
Cheng, Y.1
Wang, M.2
Yu, Y.3
Lawson, J.4
Funk, C.D.5
Fitzgerald, G.A.6
-
11
-
-
33751326323
-
Deletion of microsomal prostaglandin E synthase-1 increases sensitivity to salt loading and angiotensin II infusion
-
Jia Z., Zhang A., Zhang H., Dong Z., and Yang T. Deletion of microsomal prostaglandin E synthase-1 increases sensitivity to salt loading and angiotensin II infusion. Circ Res 99 (2006) 1243-1251
-
(2006)
Circ Res
, vol.99
, pp. 1243-1251
-
-
Jia, Z.1
Zhang, A.2
Zhang, H.3
Dong, Z.4
Yang, T.5
-
12
-
-
34547472540
-
Microsomal prostaglandin E synthase-1 and blood pressure regulation
-
Yang T. Microsomal prostaglandin E synthase-1 and blood pressure regulation. Kidney Int 72 (2007) 274-278
-
(2007)
Kidney Int
, vol.72
, pp. 274-278
-
-
Yang, T.1
-
13
-
-
40549145155
-
Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation
-
Wang M., Lee E., Song W., et al. Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation. Circulation 117 (2008) 1302-1309
-
(2008)
Circulation
, vol.117
, pp. 1302-1309
-
-
Wang, M.1
Lee, E.2
Song, W.3
-
14
-
-
33749263692
-
Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis
-
Wang M., Zukas A.M., Hui Y., Ricciotti E., Pure E., and FitzGerald G.A. Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis. Proc Natl Acad Sci USA 103 (2006) 14507-14512
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14507-14512
-
-
Wang, M.1
Zukas, A.M.2
Hui, Y.3
Ricciotti, E.4
Pure, E.5
FitzGerald, G.A.6
-
15
-
-
33746800252
-
Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury
-
Ikeda-Matsuo Y., Ota A., Fukada T., Uematsu S., Akira S., and Sasaki Y. Microsomal prostaglandin E synthase-1 is a critical factor of stroke-reperfusion injury. Proc Natl Acad Sci USA 103 (2006) 11790-11795
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11790-11795
-
-
Ikeda-Matsuo, Y.1
Ota, A.2
Fukada, T.3
Uematsu, S.4
Akira, S.5
Sasaki, Y.6
-
16
-
-
41649119130
-
Microsomal prostaglandin E2 synthase-1 deletion leads to adverse left ventricular remodeling after myocardial infarction
-
Degousee N., Fazel S., Angoulvant D., et al. Microsomal prostaglandin E2 synthase-1 deletion leads to adverse left ventricular remodeling after myocardial infarction. Circulation 117 (2008) 1701-1710
-
(2008)
Circulation
, vol.117
, pp. 1701-1710
-
-
Degousee, N.1
Fazel, S.2
Angoulvant, D.3
-
17
-
-
34548281074
-
Knockout mice lacking cPGES/p23, a constitutively expressed PGE2 synthetic enzyme, are peri-natally lethal
-
Nakatani Y., Hokonohara Y., Kakuta S., Sudo K., Iwakura Y., and Kudo I. Knockout mice lacking cPGES/p23, a constitutively expressed PGE2 synthetic enzyme, are peri-natally lethal. Biochem Biophys Res Commun 362 (2007) 387-392
-
(2007)
Biochem Biophys Res Commun
, vol.362
, pp. 387-392
-
-
Nakatani, Y.1
Hokonohara, Y.2
Kakuta, S.3
Sudo, K.4
Iwakura, Y.5
Kudo, I.6
-
18
-
-
67649435977
-
The effects of microsomal prostaglandin E synthase-1 deletion in acute cardiac ischemia in mice
-
Jun 11, Epub ahead of print
-
Wu D, Mennerich D, Arndt K, et al. The effects of microsomal prostaglandin E synthase-1 deletion in acute cardiac ischemia in mice. Prostaglandins Leukot Essent Fatty Acids. 2009 Jun 11. [Epub ahead of print].
-
(2009)
Prostaglandins Leukot Essent Fatty Acids
-
-
Wu, D.1
Mennerich, D.2
Arndt, K.3
-
19
-
-
0036604215
-
Lipopolysaccharide-dependent prostaglandin E(2) production is regulated by the glutathione-dependent prostaglandin E(2) synthase gene induced by the Toll-like receptor 4/MyD88/NF-IL6 pathway
-
Uematsu S., Matsumoto M., Takeda K., and Akira S. Lipopolysaccharide-dependent prostaglandin E(2) production is regulated by the glutathione-dependent prostaglandin E(2) synthase gene induced by the Toll-like receptor 4/MyD88/NF-IL6 pathway. J Immunol 168 (2002) 5811-5816
-
(2002)
J Immunol
, vol.168
, pp. 5811-5816
-
-
Uematsu, S.1
Matsumoto, M.2
Takeda, K.3
Akira, S.4
-
20
-
-
42449093389
-
Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis
-
Solomon S.D., Wittes J., Finn P.V., et al. Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis. Circulation 117 (2008) 2104-2113
-
(2008)
Circulation
, vol.117
, pp. 2104-2113
-
-
Solomon, S.D.1
Wittes, J.2
Finn, P.V.3
-
21
-
-
0026761179
-
Prostanoid biosynthesis and mechanisms of action
-
Smith W.L. Prostanoid biosynthesis and mechanisms of action. Am J Physiol 263 (1992) F181-191
-
(1992)
Am J Physiol
, vol.263
-
-
Smith, W.L.1
-
22
-
-
0030270063
-
Physiological and pathophysiological roles of eicosanoids in the microcirculation
-
Gerritsen M.E. Physiological and pathophysiological roles of eicosanoids in the microcirculation. Cardiovasc Res 32 (1996) 720-732
-
(1996)
Cardiovasc Res
, vol.32
, pp. 720-732
-
-
Gerritsen, M.E.1
-
23
-
-
0028807498
-
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
-
Morham S.G., Langenbach R., Loftin C.D., et al. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 83 (1995) 473-482
-
(1995)
Cell
, vol.83
, pp. 473-482
-
-
Morham, S.G.1
Langenbach, R.2
Loftin, C.D.3
-
24
-
-
0035856556
-
Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury but are protected by acute preconditioning
-
Camitta M.G., Gabel S.A., Chulada P., et al. Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury but are protected by acute preconditioning. Circulation 104 (2001) 2453-2458
-
(2001)
Circulation
, vol.104
, pp. 2453-2458
-
-
Camitta, M.G.1
Gabel, S.A.2
Chulada, P.3
-
25
-
-
0035934070
-
Risk of cardiovascular events associated with selective COX-2 inhibitors
-
Mukherjee D., Nissen S.E., and Topol E.J. Risk of cardiovascular events associated with selective COX-2 inhibitors. JAMA 286 (2001) 954-959
-
(2001)
JAMA
, vol.286
, pp. 954-959
-
-
Mukherjee, D.1
Nissen, S.E.2
Topol, E.J.3
-
26
-
-
13444263619
-
Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study
-
Graham D.J., Campen D., Hui R., et al. Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study. Lancet 365 (2005) 475-481
-
(2005)
Lancet
, vol.365
, pp. 475-481
-
-
Graham, D.J.1
Campen, D.2
Hui, R.3
-
27
-
-
42349105565
-
Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice
-
Brenneis C., Coste O., Schmidt R., et al. Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice. J Cell Mol Med 12 (2008) 639-648
-
(2008)
J Cell Mol Med
, vol.12
, pp. 639-648
-
-
Brenneis, C.1
Coste, O.2
Schmidt, R.3
-
28
-
-
2142684003
-
New developments on thromboxane and prostacyclin modulators part II: prostacyclin modulators
-
de Leval X., Hanson J., David J.L., et al. New developments on thromboxane and prostacyclin modulators part II: prostacyclin modulators. Curr Med Chem 11 (2004) 1243-1252
-
(2004)
Curr Med Chem
, vol.11
, pp. 1243-1252
-
-
de Leval, X.1
Hanson, J.2
David, J.L.3
-
29
-
-
0035975983
-
Roles of prostaglandin I(2) and thromboxane A(2) in cardiac ischemia-reperfusion injury: a study using mice lacking their respective receptors
-
Xiao C.Y., Hara A., Yuhki K., et al. Roles of prostaglandin I(2) and thromboxane A(2) in cardiac ischemia-reperfusion injury: a study using mice lacking their respective receptors. Circulation 104 (2001) 2210-2215
-
(2001)
Circulation
, vol.104
, pp. 2210-2215
-
-
Xiao, C.Y.1
Hara, A.2
Yuhki, K.3
-
30
-
-
21844453647
-
Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor
-
Hara A., Yuhki K., Fujino T., et al. Augmented cardiac hypertrophy in response to pressure overload in mice lacking the prostaglandin I2 receptor. Circulation 112 (2005) 84-92
-
(2005)
Circulation
, vol.112
, pp. 84-92
-
-
Hara, A.1
Yuhki, K.2
Fujino, T.3
-
31
-
-
1642289000
-
Inhibition of cyclooxygenase-2 improves cardiac function after myocardial infarction in the mouse
-
LaPointe M.C., Mendez M., Leung A., Tao Z., and Yang X.P. Inhibition of cyclooxygenase-2 improves cardiac function after myocardial infarction in the mouse. Am J Physiol Heart Circ Physiol 286 (2004) H1416-H1424
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.286
-
-
LaPointe, M.C.1
Mendez, M.2
Leung, A.3
Tao, Z.4
Yang, X.P.5
-
32
-
-
34848876319
-
Regulation of prostaglandin E synthases: effects of siRNA-mediated inhibition of microsomal prostaglandin E synthase-1
-
Båge T., Modéer T., Kawakami T., Quezada H.C., and Yucel-Lindberg T. Regulation of prostaglandin E synthases: effects of siRNA-mediated inhibition of microsomal prostaglandin E synthase-1. Biochim Biophys Acta 1773 (2007) 1589-1598
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1589-1598
-
-
Båge, T.1
Modéer, T.2
Kawakami, T.3
Quezada, H.C.4
Yucel-Lindberg, T.5
-
33
-
-
11144271384
-
Regulation of the membrane-localized prostaglandin E synthases mPGES-1 and mPGES-2 in cardiac myocytes and fibroblasts
-
Giannico G., Mendez M., and LaPointe M.C. Regulation of the membrane-localized prostaglandin E synthases mPGES-1 and mPGES-2 in cardiac myocytes and fibroblasts. Am J Physiol Heart Circ Physiol 288 (2005) H165-174
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
-
-
Giannico, G.1
Mendez, M.2
LaPointe, M.C.3
-
34
-
-
44649137303
-
Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice
-
Elander N., Ungerbäck J., Olsson H., Uematsu S., Akira S., and Söderkvist P. Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice. Biochem Biophys Res Commun 18 372 (2008) 249-253
-
(2008)
Biochem Biophys Res Commun
, vol.18
, Issue.372
, pp. 249-253
-
-
Elander, N.1
Ungerbäck, J.2
Olsson, H.3
Uematsu, S.4
Akira, S.5
Söderkvist, P.6
-
35
-
-
0034693050
-
Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis
-
Tanioka T., Nakatani Y., Semmyo N., Murakami M., and Kudo I. Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis. J Biol Chem 275 (2000) 32775-32782
-
(2000)
J Biol Chem
, vol.275
, pp. 32775-32782
-
-
Tanioka, T.1
Nakatani, Y.2
Semmyo, N.3
Murakami, M.4
Kudo, I.5
-
36
-
-
0036179570
-
Trophic effects of the cyclooxygenase-2 product prostaglandin E(2) in cardiac myocytes
-
Mendez M., and LaPointe M.C. Trophic effects of the cyclooxygenase-2 product prostaglandin E(2) in cardiac myocytes. Hypertension 39 (2002) 382-388
-
(2002)
Hypertension
, vol.39
, pp. 382-388
-
-
Mendez, M.1
LaPointe, M.C.2
-
37
-
-
0141733073
-
Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2
-
Murakami M., Nakashima K., Kamei D., et al. Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2. J Biol Chem 278 (2003) 37937-37947
-
(2003)
J Biol Chem
, vol.278
, pp. 37937-37947
-
-
Murakami, M.1
Nakashima, K.2
Kamei, D.3
-
38
-
-
0028818913
-
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
-
Dinchuk J.E., Car B.D., Focht R.J., et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 378 (1995) 406-409
-
(1995)
Nature
, vol.378
, pp. 406-409
-
-
Dinchuk, J.E.1
Car, B.D.2
Focht, R.J.3
-
39
-
-
0037195056
-
Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction
-
Yokoyama C., Yabuki T., Shimonishi M., et al. Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. Circulation 106 (2002) 2397-2403
-
(2002)
Circulation
, vol.106
, pp. 2397-2403
-
-
Yokoyama, C.1
Yabuki, T.2
Shimonishi, M.3
|