메뉴 건너뛰기




Volumn 35, Issue 9, 2011, Pages 594-607

The androgen receptor and its use in biological assays: Looking toward effect-based testing and its applications

Author keywords

[No Author keywords available]

Indexed keywords

ANABOLIC AGENT; ANDROGEN RECEPTOR; DEXAMETHASONE; GLUCOCORTICOID; HYDROCORTISONE; NUCLEAR RECEPTOR COACTIVATOR; NUCLEAR RECEPTOR COREPRESSOR; SELECTIVE ANDROGEN RECEPTOR MODULATOR; STEROID; STEROID RECEPTOR; TESTOSTERONE;

EID: 82855182139     PISSN: 01464760     EISSN: 19452403     Source Type: Journal    
DOI: 10.1093/anatox/35.9.594     Document Type: Article
Times cited : (20)

References (135)
  • 1
    • 42549137051 scopus 로고    scopus 로고
    • Hormone abuse in sports: the antidoping perspective
    • O. Barroso, I. Mazzoni, and O. Rabin. Hormone abuse in sports: the antidoping perspective. Asian J.Androl. 10: 391-402 (2008).
    • (2008) Asian J. Androl. , vol.10 , pp. 391-402
    • Barroso, O.1    Mazzoni, I.2    Rabin, O.3
  • 2
    • 47749104941 scopus 로고    scopus 로고
    • New and old challenges of sports drug testing
    • F. Botrè. New and old challenges of sports drug testing. J.Mass. Spectrom. 43: 903-907 (2008).
    • (2008) J. Mass. Spectrom. , vol.43 , pp. 903-907
    • Botrè, F.1
  • 3
    • 84855702393 scopus 로고    scopus 로고
    • WADA. The 2009 WADA Prohibited List. (accessed April 2011)
    • WADA. The 2009 WADA Prohibited List. http://www.wadaama.org/rtecontent/document/2008_List_En.pdf (accessed April 2011).
  • 4
    • 84855710335 scopus 로고    scopus 로고
    • WADA. The 2009 WADA Laboratory Statistics. (accessed April 2011)
    • WADA. The 2009 WADA Laboratory Statistics. http://www.wada-ama.org/Documents/Science_Medicine/Anti-Doping_Laboratories/Lab_Statistics/WADA_2009_LaboratoryStatisticsReport_Final.pdf (accessed April 2011).
  • 5
    • 2942541820 scopus 로고    scopus 로고
    • Effects of androgenic-anabolic steroids in athletes
    • F. Hartgens and H. Kuipers. Effects of androgenic-anabolic steroids in athletes. Sports Med. 34: 513-554 (2004).
    • (2004) Sports Med , vol.34 , pp. 513-554
    • Hartgens, F.1    Kuipers, H.2
  • 6
    • 0036374401 scopus 로고    scopus 로고
    • Anabolic steroids
    • C. Kuhn. Anabolic steroids. Recent Prog. Horm. Res. 57: 411-434 (2002).
    • (2002) Recent Prog. Horm. Res. , vol.57 , pp. 411-434
    • Kuhn, C.1
  • 7
    • 13444306435 scopus 로고    scopus 로고
    • Pharmacoepidemiology of anabolic androgenic steroids: a review
    • I. Thiblin and A. Petersson. Pharmacoepidemiology of anabolic androgenic steroids: a review. Fundam. Clin. Pharmacol. 19: 27-44 (2005).
    • (2005) Fundam. Clin. Pharmacol. , vol.19 , pp. 27-44
    • Thiblin, I.1    Petersson, A.2
  • 8
    • 0034811303 scopus 로고    scopus 로고
    • A review of the chemistry, biological action, and clinical applications of anabolic-androgenic steroids
    • N.T. Shahidi. A review of the chemistry, biological action, and clinical applications of anabolic-androgenic steroids. Clin. Ther. 23: 1355-1390 (2001).
    • (2001) Clin. Ther. , vol.23 , pp. 1355-1390
    • Shahidi, N.T.1
  • 10
    • 1842434983 scopus 로고    scopus 로고
    • FDA warning on unapproved performance enhancer
    • FDA warning on unapproved performance enhancer. FDA Consum. 38: 4 (2004).
    • (2004) FDA Consum , vol.38 , pp. 4
  • 11
    • 1442357999 scopus 로고    scopus 로고
    • Doping by design
    • S. Ashley. Doping by design. Sci. Am. 290: 22-23 (2004).
    • (2004) Sci. Am. , vol.290 , pp. 22-23
    • Ashley, S.1
  • 12
    • 0642342092 scopus 로고    scopus 로고
    • Drugs in sport: no dope
    • J. Knight. Drugs in sport: no dope. Nature 426: 114-115 (2003).
    • (2003) Nature , vol.426 , pp. 114-115
    • Knight, J.1
  • 13
    • 3142599890 scopus 로고    scopus 로고
    • Athletes' "designer steroid" leads to widening scandal
    • W. Kondro. Athletes' "designer steroid" leads to widening scandal. Lancet 362: 1466 (2003).
    • (2003) Lancet , vol.362 , pp. 1466
    • Kondro, W.1
  • 16
    • 41149165250 scopus 로고    scopus 로고
    • Efficient approach for the comprehensive detection of unknown anabolic steroids and metabolites in human urine by liquid chromatography-electrospray-tandem mass spectrometry
    • O.J. Pozo, K. Deventer, P.VanEenoo, and F.T. Delbeke. Efficient approach for the comprehensive detection of unknown anabolic steroids and metabolites in human urine by liquid chromatography-electrospray-tandem mass spectrometry. Anal. Chem. 80: 709-720 (2008).
    • (2008) Anal. Chem. , vol.80 , pp. 709-720
    • Pozo, O.J.1    Deventer, K.2    VanEenoo, P.3    Delbeke, F.T.4
  • 17
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/thyroid receptor superfamily members
    • M.J. Tsai and B.W. O'Malley. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem. 63: 451-486 (1994).
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 451-486
    • Tsai, M.J.1    O'Malley, B.W.2
  • 19
    • 0042770258 scopus 로고
    • Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors
    • C.S. Chang, J. Kokontis, and S.T. Liao. Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors. Proc. Natl. Acad. Sci. USA 85: 7211-7215 (1988).
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 7211-7215
    • Chang, C.S.1    Kokontis, J.2    Liao, S.T.3
  • 20
    • 0023929785 scopus 로고
    • Molecular cloning of human and rat complementary DNA encoding androgen receptors
    • C.S. Chang, J. Kokontis, and S.T. Liao. Molecular cloning of human and rat complementary DNA encoding androgen receptors. Science 240: 324-326 (1988).
    • (1988) Science , vol.240 , pp. 324-326
    • Chang, C.S.1    Kokontis, J.2    Liao, S.T.3
  • 21
    • 25444496757 scopus 로고    scopus 로고
    • Chemistry and structural biology of androgen receptor
    • W. Gao, C.E. Bohl, and J.T. Dalton. Chemistry and structural biology of androgen receptor. Chem. Rev. 105: 3352-3370 (2005).
    • (2005) Chem. Rev. , vol.105 , pp. 3352-3370
    • Gao, W.1    Bohl, C.E.2    Dalton, J.T.3
  • 22
    • 0034937870 scopus 로고    scopus 로고
    • Lessons to be learned from the androgen receptor
    • A.O. Brinkmann. Lessons to be learned from the androgen receptor. Eur. J. Dermatol. 11: 301-303 (2001).
    • (2001) Eur. J. Dermatol. , vol.11 , pp. 301-303
    • Brinkmann, A.O.1
  • 24
    • 0030925683 scopus 로고    scopus 로고
    • Steroid receptor interactions with heat shock protein and immunophilin chaperones
    • W.B. Pratt and D.O. Toft. Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr. Rev. 18: 306-360 (1997).
    • (1997) Endocr. Rev. , vol.18 , pp. 306-360
    • Pratt, W.B.1    Toft, D.O.2
  • 25
    • 17544382884 scopus 로고    scopus 로고
    • Purification and stabilization of transcriptionally active glucocorticoid receptor
    • B.S.Warren, P. Kusk, R.G.Wolford, and G.L. Hager. Purification and stabilization of transcriptionally active glucocorticoid receptor. J. Biol. Chem. 271: 11434-11440 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 11434-11440
    • Warren, B.S.1    Kusk, P.2    Wolford, R.G.3    Hager, G.L.4
  • 26
    • 67349237917 scopus 로고    scopus 로고
    • Mechanism of androgen receptor action
    • J. Li and F. Al-Azzawi. Mechanism of androgen receptor action. Maturitas 63: 142-148 (2009).
    • (2009) Maturitas , vol.63 , pp. 142-148
    • Li, J.1    Al-Azzawi, F.2
  • 27
    • 0019869344 scopus 로고
    • Molybdate permits resolution of untransformed glucocorticoid receptors from the transformed state
    • M.K. Dahmer, M.W. Quasney, S.T. Bissen, and W.B. Pratt. Molybdate permits resolution of untransformed glucocorticoid receptors from the transformed state. J. Biol. Chem. 256: 9401-9405 (1981).
    • (1981) J. Biol. Chem. , vol.256 , pp. 9401-9405
    • Dahmer, M.K.1    Quasney, M.W.2    Bissen, S.T.3    Pratt, W.B.4
  • 28
    • 33845414955 scopus 로고    scopus 로고
    • Controlling protein compartmentalization to overcome disease
    • J.R. Davis, M. Kakar, and C.S. Lim. Controlling protein compartmentalization to overcome disease. Pharm. Res. 24: 17-27 (2007).
    • (2007) Pharm. Res. , vol.24 , pp. 17-27
    • Davis, J.R.1    Kakar, M.2    Lim, C.S.3
  • 29
    • 0033279841 scopus 로고    scopus 로고
    • Transport between the cell nucleus and the cytoplasm
    • D. Gorlich and U. Kutay. Transport between the cell nucleus and the cytoplasm. Annu. Rev. Cell Dev. Biol. 15: 607-660 (1999).
    • (1999) Annu. Rev. Cell Dev. Biol. , vol.15 , pp. 607-660
    • Gorlich, D.1    Kutay, U.2
  • 31
    • 0036878979 scopus 로고    scopus 로고
    • Anabolic steroids, testosterone-precursors and virilizing androgens induce distinct activation profiles of androgen responsive promoter constructs
    • P.M. Holterhus, S. Piefke, and O. Hiort. Anabolic steroids, testosterone-precursors and virilizing androgens induce distinct activation profiles of androgen responsive promoter constructs. J. Steroid Biochem. Mol. Biol. 82: 269-275 (2002).
    • (2002) J. Steroid Biochem. Mol. Biol. , vol.82 , pp. 269-275
    • Holterhus, P.M.1    Piefke, S.2    Hiort, O.3
  • 33
    • 0027249002 scopus 로고
    • Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors
    • M. Truss and M. Beato. Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors. Endocr. Rev. 14: 459-479 (1993).
    • (1993) Endocr. Rev. , vol.14 , pp. 459-479
    • Truss, M.1    Beato, M.2
  • 34
    • 77953254302 scopus 로고    scopus 로고
    • Effect of anabolicandrogenic steroids and glucocorticoids on the kinetics of hAR and hGR nucleocytoplasmic translocation
    • A.B. Cadwallader, D.E. Rollins, and C.S. Lim. Effect of anabolicandrogenic steroids and glucocorticoids on the kinetics of hAR and hGR nucleocytoplasmic translocation. Mol. Pharm. 7: 689-698 (2010).
    • (2010) Mol. Pharm. , vol.7 , pp. 689-698
    • Cadwallader, A.B.1    Rollins, D.E.2    Lim, C.S.3
  • 39
    • 6344291192 scopus 로고    scopus 로고
    • Androgen receptor in human skeletal muscle and cultured muscle satellite cells: up-regulation by androgen treatment
    • I. Sinha-Hikim,W.E. Taylor, N.F. Gonzalez-Cadavid,W. Zheng, and S. Bhasin. Androgen receptor in human skeletal muscle and cultured muscle satellite cells: up-regulation by androgen treatment. J. Clin. Endocrinol. Metab. 89: 5245-5255 (2004).
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 5245-5255
    • Sinha-Hikim, I.1    Taylor, W.E.2    Gonzalez-Cadavid, N.F.3    Zheng, W.4    Bhasin, S.5
  • 41
    • 29344440814 scopus 로고    scopus 로고
    • Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonicalWnt signaling to down-regulate adipogenic transcription factors
    • R. Singh, J.N. Artaza,W.E. Taylor, M. Braga, X. Yuan, N.F. Gonzalez-Cadavid, and S. Bhasin. Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonicalWnt signaling to down-regulate adipogenic transcription factors. Endocrinology 147: 141-154 (2006).
    • (2006) Endocrinology , vol.147 , pp. 141-154
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Braga, M.4    Yuan, X.5    Gonzalez-Cadavid, N.F.6    Bhasin, S.7
  • 42
    • 0242468434 scopus 로고    scopus 로고
    • Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway
    • R. Singh, J.N. Artaza, W.E. Taylor, N.F. Gonzalez-Cadavid, and S. Bhasin. Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Endocrinology 144: 5081-5088 (2003).
    • (2003) Endocrinology , vol.144 , pp. 5081-5088
    • Singh, R.1    Artaza, J.N.2    Taylor, W.E.3    Gonzalez-Cadavid, N.F.4    Bhasin, S.5
  • 43
    • 42549164768 scopus 로고    scopus 로고
    • The physiological and pharmacological basis for the ergogenic effects of androgens in elite sports
    • K. Choong, K.M. Lakshman, and S. Bhasin. The physiological and pharmacological basis for the ergogenic effects of androgens in elite sports. Asian J. Androl. 10: 351-363 (2008).
    • (2008) Asian J. Androl. , vol.10 , pp. 351-363
    • Choong, K.1    Lakshman, K.M.2    Bhasin, S.3
  • 44
    • 22544451284 scopus 로고    scopus 로고
    • Androgen regulation of satellite cell function
    • Y. Chen, J.D. Zajac, and H.E. MacLean. Androgen regulation of satellite cell function. J. Endocrinol. 186: 21-31 (2005).
    • (2005) J. Endocrinol. , vol.186 , pp. 21-31
    • Chen, Y.1    Zajac, J.D.2    MacLean, H.E.3
  • 45
    • 0024595381 scopus 로고
    • Satellite cell proliferation and increase in the number ofmyonuclei induced by testosterone in the levator ani muscle of the adult female rat
    • Y. Joubert and C. Tobin. Satellite cell proliferation and increase in the number ofmyonuclei induced by testosterone in the levator ani muscle of the adult female rat. Dev. Biol. 131: 550-557 (1989).
    • (1989) Dev. Biol. , vol.131 , pp. 550-557
    • Joubert, Y.1    Tobin, C.2
  • 46
    • 0038678058 scopus 로고    scopus 로고
    • Testosteroneinduced muscle hypertrophy is associated with an increase in satellite cell number in healthy, young men
    • I. Sinha-Hikim, S.M. Roth, M.I. Lee, and S. Bhasin. Testosteroneinduced muscle hypertrophy is associated with an increase in satellite cell number in healthy, young men. Am. J. Physiol. Endocrinol. Metab. 285: E197-E205 (2003).
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.285
    • Sinha-Hikim, I.1    Roth, S.M.2    Lee, M.I.3    Bhasin, S.4
  • 47
    • 0030008005 scopus 로고    scopus 로고
    • Testosterone up-regulates androgen receptors and decreases differentiation of porcine myogenic satellite cells in vitro
    • M. Doumit, D.R. Cook, and R.A. Merkel. Testosterone up-regulates androgen receptors and decreases differentiation of porcine myogenic satellite cells in vitro. Endocrinology 137: 1385-1394 (1996).
    • (1996) Endocrinology , vol.137 , pp. 1385-1394
    • Doumit, M.1    Cook, D.R.2    Merkel, R.A.3
  • 48
    • 37349118115 scopus 로고    scopus 로고
    • Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex
    • H.V. Heemers and D.J. Tindall. Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. Endocr. Rev. 28: 778-808 (2007).
    • (2007) Endocr. Rev. , vol.28 , pp. 778-808
    • Heemers, H.V.1    Tindall, D.J.2
  • 49
    • 15544371000 scopus 로고    scopus 로고
    • Ligand control of coregulator recruitment to nuclear receptors
    • K.W. Nettles and G.L. Greene. Ligand control of coregulator recruitment to nuclear receptors. Annu. Rev. Physiol. 67: 309-333 (2005).
    • (2005) Annu. Rev. Physiol. , vol.67 , pp. 309-333
    • Nettles, K.W.1    Greene, G.L.2
  • 50
    • 0345859565 scopus 로고    scopus 로고
    • The roles of sex steroid receptor coregulators in cancer
    • X. Gao, B.W. Loggie, and Z. Nawaz. The roles of sex steroid receptor coregulators in cancer. Mol. Cancer 1: 1-7 (2002).
    • (2002) Mol. Cancer , vol.1 , pp. 1-7
    • Gao, X.1    Loggie, B.W.2    Nawaz, Z.3
  • 51
    • 33646138016 scopus 로고    scopus 로고
    • Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity
    • K. Pereira de Jesus-Tran, P.L. Cote, L. Cantin, J. Blanchet, F. Labrie, and R. Breton. Comparison of crystal structures of human androgen receptor ligand-binding domain complexed with various agonists reveals molecular determinants responsible for binding affinity. Protein Sci. 15: 987-999 (2006).
    • (2006) Protein Sci , vol.15 , pp. 987-999
    • Pereira de Jesus-Tran, K.1    Cote, P.L.2    Cantin, L.3    Blanchet, J.4    Labrie, F.5    Breton, R.6
  • 52
    • 0037621919 scopus 로고    scopus 로고
    • Dissociation of steroid receptor coactivator 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification of the ligand-receptor interface: the role of tyrosine 735
    • A. Stevens, H. Garside, A. Berry, C. Waters, A. White, and D. Ray. Dissociation of steroid receptor coactivator 1 and nuclear receptor corepressor recruitment to the human glucocorticoid receptor by modification of the ligand-receptor interface: the role of tyrosine 735. Mol. Endocrinol. 17: 845-859 (2003).
    • (2003) Mol. Endocrinol. , vol.17 , pp. 845-859
    • Stevens, A.1    Garside, H.2    Berry, A.3    Waters, C.4    White, A.5    Ray, D.6
  • 55
    • 19344376991 scopus 로고    scopus 로고
    • Recognition and accommodation at the androgen receptor coactivator binding interface
    • E. Hur, S.J. Pfaff, E.S. Payne, H. Grøn, B.M. Buehrer, and R.J. Fletterick. Recognition and accommodation at the androgen receptor coactivator binding interface. PLoS Biol. 2: E274 (2004).
    • (2004) PLoS Biol , vol.2
    • Hur, E.1    Pfaff, S.J.2    Payne, E.S.3    Grøn, H.4    Buehrer, B.M.5    Fletterick, R.J.6
  • 56
    • 0036219918 scopus 로고    scopus 로고
    • Androgen receptor (AR) coregulators: an overview
    • C.A. Heinlein and C. Chang. Androgen receptor (AR) coregulators: an overview. Endocr. Rev. 23: 175-200 (2002).
    • (2002) Endocr. Rev. , vol.23 , pp. 175-200
    • Heinlein, C.A.1    Chang, C.2
  • 58
    • 0346496776 scopus 로고    scopus 로고
    • Androgens
    • 10th ed., J.G. Hardman, L.E. Limbird, and A.G. Gilman, Eds. McGraw-Hill, New York, NY
    • P. Snyder. Androgens. In Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10th ed., J.G. Hardman, L.E. Limbird, and A.G. Gilman, Eds. McGraw-Hill, New York, NY, 2001, pp 1635-1648.
    • (2001) Goodman and Gilman's The Pharmacological Basis of Therapeutics , pp. 1635-1648
    • Snyder, P.1
  • 59
    • 0029987681 scopus 로고    scopus 로고
    • Metabolism of anabolic androgenic steroids
    • W. Schanzer. Metabolism of anabolic androgenic steroids. Clin. Chem. 42: 1001-1020 (1996).
    • (1996) Clin. Chem. , vol.42 , pp. 1001-1020
    • Schanzer, W.1
  • 60
    • 0025296967 scopus 로고
    • Glucocorticoid antagonism by exercise and androgenic-anabolic steroids
    • R. Hickson, S. Czerwinski, M. Falduto, and A. Young. Glucocorticoid antagonism by exercise and androgenic-anabolic steroids. Med. Sci. Sports Exerc. 22: 331-340 (1990).
    • (1990) Med. Sci. Sports Exerc. , vol.22 , pp. 331-340
    • Hickson, R.1    Czerwinski, S.2    Falduto, M.3    Young, A.4
  • 61
    • 0027346409 scopus 로고
    • Exercise and inhibition of glucocorticoid-induced muscle atrophy
    • R.C. Hickson and J.R. Marone. Exercise and inhibition of glucocorticoid-induced muscle atrophy. Exerc. Sport Sci. Rev. 21: 135-167 (1993).
    • (1993) Exerc. Sport Sci. Rev. , vol.21 , pp. 135-167
    • Hickson, R.C.1    Marone, J.R.2
  • 62
    • 0016622562 scopus 로고
    • Interaction of anabolic steroids with glucocorticoid receptor sites in rat muscle cytosol
    • M. Mayer and F. Rosen. Interaction of anabolic steroids with glucocorticoid receptor sites in rat muscle cytosol. Am. J. Physiol. 229: 1381-1386 (1975).
    • (1975) Am. J. Physiol. , vol.229 , pp. 1381-1386
    • Mayer, M.1    Rosen, F.2
  • 66
    • 84855664859 scopus 로고    scopus 로고
    • (accessed June 2010)
    • http://anabolicminds.com/forum/steroids/9989-vida-textandrogens. html (accessed June 2010).
  • 67
    • 84855664860 scopus 로고    scopus 로고
    • (accessed June 2010)
    • http://www.demonoid.com/files/details/1643294/008522825736/(accessed June 2010).
  • 68
    • 44349157577 scopus 로고    scopus 로고
    • Pharmacology of anabolic steroids
    • A.T. Kicman. Pharmacology of anabolic steroids. Br. J. Pharmacol. 154: 502-521 (2008).
    • (2008) Br. J. Pharmacol. , vol.154 , pp. 502-521
    • Kicman, A.T.1
  • 69
    • 67549142234 scopus 로고    scopus 로고
    • Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit
    • M.L. Mohler, C.E. Bohl, A. Jones, C.C. Coss, R. Narayanan, Y. He, D.J. Hwang, J.T. Dalton, and D.D. Miller. Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit. J. Med. Chem. 52: 3597-3617 (2009).
    • (2009) J. Med. Chem. , vol.52 , pp. 3597-3617
    • Mohler, M.L.1    Bohl, C.E.2    Jones, A.3    Coss, C.C.4    Narayanan, R.5    He, Y.6    Hwang, D.J.7    Dalton, J.T.8    Miller, D.D.9
  • 72
    • 1842627842 scopus 로고    scopus 로고
    • Pharmacokinetics of S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide in rats, a non-steroidal selective androgen receptor modulator
    • J.D. Kearbey, D.Wu,W. Gao, D.D. Miller, and J.T. Dalton. Pharmacokinetics of S-3-(4-acetylamino-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide in rats, a non-steroidal selective androgen receptor modulator. Xenobiotica 34: 273-280 (2004).
    • (2004) Xenobiotica , vol.34 , pp. 273-280
    • Kearbey, J.D.1    Wu, D.2    Gao, W.3    Miller, D.D.4    Dalton, J.T.5
  • 73
    • 22544467523 scopus 로고    scopus 로고
    • Discovery and therapeutic promise of selective androgen receptor modulators
    • J. Chen, J. Kim, and J.T. Dalton. Discovery and therapeutic promise of selective androgen receptor modulators. Mol. Interv. 5: 173-188 (2005).
    • (2005) Mol. Interv. , vol.5 , pp. 173-188
    • Chen, J.1    Kim, J.2    Dalton, J.T.3
  • 74
    • 77449160132 scopus 로고    scopus 로고
    • Synthetic anabolic agents: steroids and nonsteroidal selective androgen receptor modulators
    • M. Thevis and W. Schänzer. Synthetic anabolic agents: steroids and nonsteroidal selective androgen receptor modulators. Handb. Exp. Pharmacol. 195: 99-126 (2010).
    • (2010) Handb. Exp. Pharmacol. , vol.195 , pp. 99-126
    • Thevis, M.1    Schänzer, W.2
  • 75
    • 18044371228 scopus 로고    scopus 로고
    • Androgen receptor-cofactor interactions as targets for new drug discovery
    • C.Y. Chang and D.P. McDonnell. Androgen receptor-cofactor interactions as targets for new drug discovery. Trends Pharmacol. Sci. 26: 225-228 (2005).
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 225-228
    • Chang, C.Y.1    McDonnell, D.P.2
  • 76
    • 82855178424 scopus 로고    scopus 로고
    • WADA. The 2010 Prohibited List. International Standard.WADA, Montreal, QC, Canada
    • WADA. TheWorld Anti-Doping Code. The 2010 Prohibited List. International Standard.WADA, Montreal, QC, Canada, 2010.
    • (2010) TheWorld Anti-Doping Code
  • 77
    • 47749101721 scopus 로고    scopus 로고
    • Mass spectrometry of selective androgen receptor modulators
    • M. Thevis and W. Schanzer. Mass spectrometry of selective androgen receptor modulators. J. Mass Spectrom. 43: 865-876 (2008).
    • (2008) J. Mass Spectrom. , vol.43 , pp. 865-876
    • Thevis, M.1    Schanzer, W.2
  • 78
    • 40849120748 scopus 로고    scopus 로고
    • Aryl-propionamide-derived selective androgen receptor modulators: liquid chromatography-tandem mass spectrometry characterization of the in vitro synthesized metabolites for doping control purposes
    • T. Kuuranne, A. Leinonen, W. Schanzer, M. Kamber, R. Kostiainen, and M. Thevis. Aryl-propionamide-derived selective androgen receptor modulators: liquid chromatography-tandem mass spectrometry characterization of the in vitro synthesized metabolites for doping control purposes. Drug Metab. Dispos. 36: 571-581 (2008).
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 571-581
    • Kuuranne, T.1    Leinonen, A.2    Schanzer, W.3    Kamber, M.4    Kostiainen, R.5    Thevis, M.6
  • 79
    • 42449084465 scopus 로고    scopus 로고
    • Determination of benzimidazoleand bicyclic hydantoin-derived selective androgen receptor antagonists and agonists in human urine using LC-MS/MS
    • M. Thevis, M. Kohler, A. Thomas, J. Maurer, N. Schlorer, M. Kamber, and W. Schanzer. Determination of benzimidazoleand bicyclic hydantoin-derived selective androgen receptor antagonists and agonists in human urine using LC-MS/MS. Anal. Bioanal. Chem. 391: 251-261 (2008).
    • (2008) Anal. Bioanal. Chem. , vol.391 , pp. 251-261
    • Thevis, M.1    Kohler, M.2    Thomas, A.3    Maurer, J.4    Schlorer, N.5    Kamber, M.6    Schanzer, W.7
  • 80
    • 65749089277 scopus 로고    scopus 로고
    • Emerging drugs: mechanism of action, mass spectrometry and doping control analysis
    • M. Thevis, A. Thomas, M. Kohler, S. Beuck, and W. Schanzer. Emerging drugs: mechanism of action, mass spectrometry and doping control analysis. J.Mass Spectrom. 44: 442-460 (2009).
    • (2009) J. Mass Spectrom. , vol.44 , pp. 442-460
    • Thevis, M.1    Thomas, A.2    Kohler, M.3    Beuck, S.4    Schanzer, W.5
  • 81
    • 57349182202 scopus 로고    scopus 로고
    • Illicit organogenesis: methods and substances of doping and manipulation
    • M. Thevis and W. Schanzer. Illicit organogenesis: methods and substances of doping and manipulation. Organogenesis 4: 264-271 (2008).
    • (2008) Organogenesis , vol.4 , pp. 264-271
    • Thevis, M.1    Schanzer, W.2
  • 82
    • 37649023920 scopus 로고    scopus 로고
    • New drugs and methods of doping and manipulation
    • M. Thevis, M. Kohler, and W. Schanzer. New drugs and methods of doping and manipulation. Drug Discov. Today 13: 59-66 (2008).
    • (2008) Drug Discov. Today , vol.13 , pp. 59-66
    • Thevis, M.1    Kohler, M.2    Schanzer, W.3
  • 84
    • 33846624349 scopus 로고    scopus 로고
    • A general screening method for doping agents in human urine by solid phase extraction and liquid chromatography/time-of-flight mass spectrometry
    • M. Kolmonen, A. Leinonen, A. Pelander, and I. Ojanperä. A general screening method for doping agents in human urine by solid phase extraction and liquid chromatography/time-of-flight mass spectrometry. Anal. Chim. Acta 585: 94-102 (2007).
    • (2007) Anal. Chim. Acta , vol.585 , pp. 94-102
    • Kolmonen, M.1    Leinonen, A.2    Pelander, A.3    Ojanperä, I.4
  • 85
    • 37649013598 scopus 로고    scopus 로고
    • Application of fast gas chromatography/mass spectrometry for the rapid screening of synthetic anabolic steroids and other drugs in anti-doping analysis
    • M. Mazzarino, M. Orengia, and F. Botre. Application of fast gas chromatography/mass spectrometry for the rapid screening of synthetic anabolic steroids and other drugs in anti-doping analysis. Rapid Commun. Mass Spectrom. 21: 4117-4124 (2007).
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , pp. 4117-4124
    • Mazzarino, M.1    Orengia, M.2    Botre, F.3
  • 86
    • 34748883693 scopus 로고    scopus 로고
    • Development and validation of a qualitative screening method for the detection of exogenous anabolic steroids in urine by liquid chromatography-tandem mass spectrometry
    • O.J. Pozo, P. Van Eenoo, K. Deventer, and F.T. Delbeke. Development and validation of a qualitative screening method for the detection of exogenous anabolic steroids in urine by liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem. 389: 1209-1224 (2007).
    • (2007) Anal. Bioanal. Chem. , vol.389 , pp. 1209-1224
    • Pozo, O.J.1    Van Eenoo, P.2    Deventer, K.3    Delbeke, F.T.4
  • 87
    • 37549025787 scopus 로고    scopus 로고
    • In vitro bioassays for androgens and their diagnostic applications
    • P. Roy, M. Alevizaki, and I. Huhtaniemi. In vitro bioassays for androgens and their diagnostic applications. Hum. Reprod.Update 14: 73-82 (2008).
    • (2008) Hum. Reprod. Update , vol.14 , pp. 73-82
    • Roy, P.1    Alevizaki, M.2    Huhtaniemi, I.3
  • 88
    • 61849096693 scopus 로고    scopus 로고
    • Validation and application of a yeast bioassay for screening androgenic activity in calf urine and feed
    • T.F. Bovee, G. Bor, H.H. Heskamp, J.J. Lasaroms, M.B. Sanders, and M.W. Nielen. Validation and application of a yeast bioassay for screening androgenic activity in calf urine and feed. Anal. Chim. Acta 637: 225-234 (2009).
    • (2009) Anal. Chim. Acta , vol.637 , pp. 225-234
    • Bovee, T.F.1    Bor, G.2    Heskamp, H.H.3    Lasaroms, J.J.4    Sanders, M.B.5    Nielen, M.W.6
  • 91
    • 0031105822 scopus 로고    scopus 로고
    • Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay
    • K.W. Gaido, L.S. Leonard, S. Lovell, J.C. Gould, D. Babai, C.J. Portier, and D.P. McDonnell. Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. Toxicol. Appl. Pharmacol. 143: 205-212 (1997).
    • (1997) Toxicol. Appl. Pharmacol. , vol.143 , pp. 205-212
    • Gaido, K.W.1    Leonard, L.S.2    Lovell, S.3    Gould, J.C.4    Babai, D.5    Portier, C.J.6    McDonnell, D.P.7
  • 92
    • 0037377230 scopus 로고    scopus 로고
    • Novel yeast bioassay system for detection of androgenic and antiandrogenic compounds
    • H.J. Lee, Y.S. Lee, H.B. Kwon, and K. Lee. Novel yeast bioassay system for detection of androgenic and antiandrogenic compounds. Toxicol. In Vitro 17: 237-244 (2003).
    • (2003) Toxicol. In Vitro , vol.17 , pp. 237-244
    • Lee, H.J.1    Lee, Y.S.2    Kwon, H.B.3    Lee, K.4
  • 93
    • 23744463526 scopus 로고    scopus 로고
    • Bioluminescent yeast assays for detecting estrogenic and androgenic activity in different matrices
    • P. Leskinen, E. Michelini, D. Picard, M. Karp, and M.Virta. Bioluminescent yeast assays for detecting estrogenic and androgenic activity in different matrices. Chemosphere 61: 259-266 (2005).
    • (2005) Chemosphere , vol.61 , pp. 259-266
    • Leskinen, P.1    Michelini, E.2    Picard, D.3    Karp, M.4    Virta, M.5
  • 94
    • 0345201750 scopus 로고    scopus 로고
    • A yeast screen system for aromatase inhibitors and ligands for androgen receptor: yeast cells transformed with aromatase and androgen receptor
    • P. Mak, F.D. Cruz, and S. Chen. A yeast screen system for aromatase inhibitors and ligands for androgen receptor: yeast cells transformed with aromatase and androgen receptor. Environ. Health Perspect. 107: 855-860 (1999).
    • (1999) Environ. Health Perspect. , vol.107 , pp. 855-860
    • Mak, P.1    Cruz, F.D.2    Chen, S.3
  • 95
    • 15944402750 scopus 로고    scopus 로고
    • A new recombinant cell-based bioluminescent assay for sensitive androgen-like compound detection
    • E. Michelini, P. Leskinen, M.Virta, M. Karp, and A. Roda. A new recombinant cell-based bioluminescent assay for sensitive androgen-like compound detection. Biosens. Bioelectron. 20: 2261-2267 (2005).
    • (2005) Biosens. Bioelectron. , vol.20 , pp. 2261-2267
    • Michelini, E.1    Leskinen, P.2    Virta, M.3    Karp, M.4    Roda, A.5
  • 96
    • 25444452108 scopus 로고    scopus 로고
    • Recombinant cell-based bioluminescence assay for androgen bioactivity determination in clinical samples
    • E. Michelini, M. Magliulo, P. Leskinen, M. Virta, M. Karp, and A. Roda. Recombinant cell-based bioluminescence assay for androgen bioactivity determination in clinical samples. Clin. Chem. 51: 1995-1998 (2005).
    • (2005) Clin. Chem. , vol.51 , pp. 1995-1998
    • Michelini, E.1    Magliulo, M.2    Leskinen, P.3    Virta, M.4    Karp, M.5    Roda, A.6
  • 98
    • 0031656115 scopus 로고    scopus 로고
    • Several environmental oestrogens are also anti-androgens
    • P. Sohoni and J.P. Sumpter. Several environmental oestrogens are also anti-androgens. J. Endocrinol. 158: 327-339 (1998).
    • (1998) J. Endocrinol. , vol.158 , pp. 327-339
    • Sohoni, P.1    Sumpter, J.P.2
  • 99
    • 46749138616 scopus 로고    scopus 로고
    • Detection of anabolic steroid abuse using a yeast transactivation system
    • O. Zierau, S. Lehmann, G. Vollmer, W. Schanzer, and P. Diel. Detection of anabolic steroid abuse using a yeast transactivation system. Steroids 73: 1143-1147 (2008).
    • (2008) Steroids , vol.73 , pp. 1143-1147
    • Zierau, O.1    Lehmann, S.2    Vollmer, G.3    Schanzer, W.4    Diel, P.5
  • 100
    • 37549066675 scopus 로고    scopus 로고
    • Androgen receptor transactivation assay using green fluorescent protein as a reporter
    • V. Beck, E. Reiter, and A. Jungbauer. Androgen receptor transactivation assay using green fluorescent protein as a reporter. Anal. Biochem. 373: 263-271 (2008).
    • (2008) Anal. Biochem. , vol.373 , pp. 263-271
    • Beck, V.1    Reiter, E.2    Jungbauer, A.3
  • 101
    • 0035499955 scopus 로고    scopus 로고
    • Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor
    • B.M. Blankvoort, E.M. de Groene, A.P. van Meeteren-Kreikamp, R.F.Witkamp, R.J. Rodenburg, and J.M. Aarts. Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor. Anal. Biochem. 298: 93-102 (2001).
    • (2001) Anal. Biochem. , vol.298 , pp. 93-102
    • Blankvoort, B.M.1    de Groene, E.M.2    van Meeteren-Kreikamp, A.P.3    Witkamp, R.F.4    Rodenburg, R.J.5    Aarts, J.M.6
  • 103
    • 0037333156 scopus 로고    scopus 로고
    • Tibolone is not converted by human aromatase to 7alpha-methyl-17alpha-ethynylestradiol (7alpha-MEE): analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS
    • M.E. de Gooyer, H.M. Oppers-Tiemissen, D. Leysen, H.A. Verheul, and H.J. Kloosterboer. Tibolone is not converted by human aromatase to 7alpha-methyl-17alpha-ethynylestradiol (7alpha-MEE): analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS. Steroids 68: 235-243 (2003).
    • (2003) Steroids , vol.68 , pp. 235-243
    • de Gooyer, M.E.1    Oppers-Tiemissen, H.M.2    Leysen, D.3    Verheul, H.A.4    Kloosterboer, H.J.5
  • 106
    • 34248593017 scopus 로고    scopus 로고
    • Antiandrogenic activity of norgestimate in a human androgen-dependent stable-transfected cell line
    • F. Paris, F. Rabeolina, P. Balaguer, A. Bacquet, and C. Sultan. Antiandrogenic activity of norgestimate in a human androgen-dependent stable-transfected cell line. Gynecol. Endocrinol. 23: 193-197 (2007).
    • (2007) Gynecol. Endocrinol. , vol.23 , pp. 193-197
    • Paris, F.1    Rabeolina, F.2    Balaguer, P.3    Bacquet, A.4    Sultan, C.5
  • 107
    • 0036174089 scopus 로고    scopus 로고
    • A new recombinant cell bioassay for ultrasensitive determination of serum estrogenic bioactivity in children
    • F. Paris, N. Servant, B. Terouanne, P. Balaguer, J.C. Nicolas, and C. Sultan. A new recombinant cell bioassay for ultrasensitive determination of serum estrogenic bioactivity in children. J. Clin. Endocrinol. Metab. 87: 791-797 (2002).
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 791-797
    • Paris, F.1    Servant, N.2    Terouanne, B.3    Balaguer, P.4    Nicolas, J.C.5    Sultan, C.6
  • 108
    • 0037203496 scopus 로고    scopus 로고
    • Evaluation of androgenic bioactivity in human serum by recombinant cell line: preliminary results
    • F. Paris, N. Servant, B. Terouanne, and C. Sultan. Evaluation of androgenic bioactivity in human serum by recombinant cell line: preliminary results. Mol. Cell Endocrinol. 198: 123-129 (2002).
    • (2002) Mol. Cell Endocrinol. , vol.198 , pp. 123-129
    • Paris, F.1    Servant, N.2    Terouanne, B.3    Sultan, C.4
  • 110
    • 33748064349 scopus 로고    scopus 로고
    • Determination of androgen bioactivity in human serum samples using a recombinant cell based in vitro bioassay
    • P. Roy, S. Franks, M. Read, and I.T. Huhtaniemi. Determination of androgen bioactivity in human serum samples using a recombinant cell based in vitro bioassay. J. Steroid Biochem.Mol. Biol. 101: 68-77 (2006).
    • (2006) J. Steroid Biochem. Mol. Biol. , vol.101 , pp. 68-77
    • Roy, P.1    Franks, S.2    Read, M.3    Huhtaniemi, I.T.4
  • 112
    • 12344265705 scopus 로고    scopus 로고
    • Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays
    • E. Sonneveld, H.J. Jansen, J.A. Riteco, A. Brouwer and B. van der Burg. Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays. Toxicol. Sci. 83: 136-148 (2005).
    • (2005) Toxicol. Sci. , vol.83 , pp. 136-148
    • Sonneveld, E.1    Jansen, H.J.2    Riteco, J.A.3    Brouwer, A.4    van der Burg, B.5
  • 114
    • 0037379703 scopus 로고    scopus 로고
    • Mutation of the androgen receptor at amino acid 708 (Gly-->Ala) abolishes partial agonist activity of steroidal antiandrogens
    • B. Terouanne, P. Nirdé, F. Rabenoelina,W. Bourguet, C. Sultan, and G. Auzou. Mutation of the androgen receptor at amino acid 708 (Gly-->Ala) abolishes partial agonist activity of steroidal antiandrogens. Mol. Pharmacol. 63: 791-798 (2003).
    • (2003) Mol. Pharmacol. , vol.63 , pp. 791-798
    • Terouanne, B.1    Nirdé, P.2    Rabenoelina, F.3    Bourguet, W.4    Sultan, C.5    Auzou, G.6
  • 115
    • 56249084597 scopus 로고    scopus 로고
    • Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects
    • A.T. Szafran, M. Szwarc, M. Marcelli, and M.A. Mancini. Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects. PLoS One 3: e3605 (2008).
    • (2008) PLoS One , vol.3
    • Szafran, A.T.1    Szwarc, M.2    Marcelli, M.3    Mancini, M.A.4
  • 116
    • 31444441045 scopus 로고    scopus 로고
    • Transfection with steroid-responsive reporter constructs shows glucocorticoid rather than androgen responsiveness in cultured Sertoli cells
    • E. Denolet, K.D. Gendt, J.V. Swinnen, G. Verrijdt, L. Deboel, T. Roskams, and G. Verhoeven. Transfection with steroid-responsive reporter constructs shows glucocorticoid rather than androgen responsiveness in cultured Sertoli cells. J. Steroid Biochem. Mol. Biol. 98: 164-173 (2006).
    • (2006) J. Steroid Biochem. Mol. Biol. , vol.98 , pp. 164-173
    • Denolet, E.1    Gendt, K.D.2    Swinnen, J.V.3    Verrijdt, G.4    Deboel, L.5    Roskams, T.6    Verhoeven, G.7
  • 117
    • 0036192083 scopus 로고    scopus 로고
    • A novel cell line, MDA-kb2, that stably expresses an androgenand glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists
    • V.S. Wilson, K. Bobseine, C.R. Lambright, and L.E. Gray, Jr. A novel cell line, MDA-kb2, that stably expresses an androgenand glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists. Toxicol. Sci. 66: 69-81 (2002).
    • (2002) Toxicol. Sci. , vol.66 , pp. 69-81
    • Wilson, V.S.1    Bobseine, K.2    Lambright, C.R.3    Gray Jr., L.E.4
  • 119
    • 0029778413 scopus 로고    scopus 로고
    • The androgen-specific probasin response element 2 interacts differentially with androgen and glucocorticoid receptors
    • F. Claessens, P. Alen, A. Devos, B. Peeters, G. Verhoeven, and W. Rombauts. The androgen-specific probasin response element 2 interacts differentially with androgen and glucocorticoid receptors. J. Biol. Chem. 271: 19013-19016 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 19013-19016
    • Claessens, F.1    Alen, P.2    Devos, A.3    Peeters, B.4    Verhoeven, G.5    Rombauts, W.6
  • 121
    • 0034697122 scopus 로고    scopus 로고
    • Differences in DNA binding characteristics of the androgen and glucocorticoid receptors can determine hormone-specific responses
    • E. Schoenmakers, G. Verrijdt, B. Peeters, G. Verhoeven, W. Rombauts, and F. Claessens. Differences in DNA binding characteristics of the androgen and glucocorticoid receptors can determine hormone-specific responses. J. Biol. Chem. 275: 12290-12297 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 12290-12297
    • Schoenmakers, E.1    Verrijdt, G.2    Peeters, B.3    Verhoeven, G.4    Rombauts, W.5    Claessens, F.6
  • 122
    • 0033305722 scopus 로고    scopus 로고
    • Androgen specificity of a response unit upstream of the human secretory component gene is mediated by differential receptor binding to an essential androgen response element
    • G. Verrijdt, E. Schoenmakers, P. Alen, A. Haelens, B. Peeters, W. Rombauts, and F. Claessens. Androgen specificity of a response unit upstream of the human secretory component gene is mediated by differential receptor binding to an essential androgen response element. Mol. Endocrinol. 13: 1558-1570 (1999).
    • (1999) Mol. Endocrinol. , vol.13 , pp. 1558-1570
    • Verrijdt, G.1    Schoenmakers, E.2    Alen, P.3    Haelens, A.4    Peeters, B.5    Rombauts, W.6    Claessens, F.7
  • 123
    • 0034697359 scopus 로고    scopus 로고
    • Change of specificity mutations in androgen-selective enhancers. Evidence for a role of differential DNA binding by the androgen receptor
    • G. Verrijdt, E. Schoenmakers, A. Haelens, B. Peeters, G. Verhoeven, W. Rombauts, and F. Claessens. Change of specificity mutations in androgen-selective enhancers. Evidence for a role of differential DNA binding by the androgen receptor. J. Biol. Chem. 275: 12298-12305 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 12298-12305
    • Verrijdt, G.1    Schoenmakers, E.2    Haelens, A.3    Peeters, B.4    Verhoeven, G.5    Rombauts, W.6    Claessens, F.7
  • 124
    • 0037809279 scopus 로고    scopus 로고
    • Dynamic shuttling and intranuclear mobility of nuclear hormone receptors
    • P. Maruvada, C.T. Baumann, G.L. Hager, and P.M. Yen. Dynamic shuttling and intranuclear mobility of nuclear hormone receptors. J. Biol. Chem. 278: 12425-12432 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 12425-12432
    • Maruvada, P.1    Baumann, C.T.2    Hager, G.L.3    Yen, P.M.4
  • 125
    • 0037372002 scopus 로고    scopus 로고
    • Molecular determinants of glucocorticoid receptor mobility in living cells: the importance of ligand affinity
    • M.J. Schaaf and J.A. Cidlowski. Molecular determinants of glucocorticoid receptor mobility in living cells: the importance of ligand affinity. Mol. Cell Biol. 23: 1922-1934 (2003).
    • (2003) Mol. Cell Biol. , vol.23 , pp. 1922-1934
    • Schaaf, M.J.1    Cidlowski, J.A.2
  • 126
    • 7244247363 scopus 로고    scopus 로고
    • Estrogen response element-dependent regulation of transcriptional activation of estrogen receptors alpha and beta by coactivators and corepressors
    • C.M. Klinge, S.C. Jernigan, K.A. Mattingly, K.E. Risinger, and J. Zhang. Estrogen response element-dependent regulation of transcriptional activation of estrogen receptors alpha and beta by coactivators and corepressors. J. Mol. Endocrinol. 33: 387-410 (2004).
    • (2004) J. Mol. Endocrinol. , vol.33 , pp. 387-410
    • Klinge, C.M.1    Jernigan, S.C.2    Mattingly, K.A.3    Risinger, K.E.4    Zhang, J.5
  • 128
    • 0032807750 scopus 로고    scopus 로고
    • A novel role for helix 12 of retinoid X receptor in regulating repression
    • J. Zhang, X. Hu, and M.A. Lazar. A novel role for helix 12 of retinoid X receptor in regulating repression. Mol. Cell Biol. 19: 6448-6457 (1999).
    • (1999) Mol. Cell Biol. , vol.19 , pp. 6448-6457
    • Zhang, J.1    Hu, X.2    Lazar, M.A.3
  • 129
    • 70350602531 scopus 로고    scopus 로고
    • Comparison of in vitro hormone activities of selected phthalates using reporter gene assays
    • O. Shen, G. Du, H. Sun,W.Wu, Y. Jiang, L. Song, and X.Wang. Comparison of in vitro hormone activities of selected phthalates using reporter gene assays. Toxicol. Lett. 191: 9-14 (2009).
    • (2009) Toxicol. Lett. , vol.191 , pp. 9-14
    • Shen, O.1    Du, G.2    Sun, H.3    Wu, W.4    Jiang, Y.5    Song, L.6    Wang, X.7
  • 130
    • 0142211276 scopus 로고    scopus 로고
    • Identification and characterization of a ligand-regulated nuclear export signal in androgen receptor
    • A.J. Saporita, Q. Zhang, N. Navai, Z. Dincer, J. Hahn, X. Cai, and Z.Wang. Identification and characterization of a ligand-regulated nuclear export signal in androgen receptor. J. Biol. Chem. 278: 41998-42005 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 41998-42005
    • Saporita, A.J.1    Zhang, Q.2    Navai, N.3    Dincer, Z.4    Hahn, J.5    Cai, X.6    Wang, Z.7
  • 131
    • 0034663560 scopus 로고    scopus 로고
    • A natural sequence consisting of overlapping glucocorticoid-responsive elements mediates glucocorticoid, but not androgen, regulation of gene expression
    • C. Massaad, M. Garlatti, E.M. Wilson, F. Cadepond, and R. Barouki. A natural sequence consisting of overlapping glucocorticoid-responsive elements mediates glucocorticoid, but not androgen, regulation of gene expression. Biochem. J. 350 Pt 1: 123-129 (2000).
    • (2000) Biochem. J. , vol.350 , Issue.PART 1 , pp. 123-129
    • Massaad, C.1    Garlatti, M.2    Wilson, E.M.3    Cadepond, F.4    Barouki, R.5
  • 133
    • 0242351903 scopus 로고    scopus 로고
    • Antiandrogenic activity of the phytoestrogens naringenin, 6-(1,1-dimethylallyl)naringenin and 8-prenylnaringenin
    • O. Zierau, C. Morrissey, R.W. Watson, P. Schwab, S. Kolba, P. Metz, and G. Vollmer. Antiandrogenic activity of the phytoestrogens naringenin, 6-(1,1-dimethylallyl)naringenin and 8-prenylnaringenin. Planta Med. 69: 856-858 (2003).
    • (2003) Planta Med , vol.69 , pp. 856-858
    • Zierau, O.1    Morrissey, C.2    Watson, R.W.3    Schwab, P.4    Kolba, S.5    Metz, P.6    Vollmer, G.7
  • 135
    • 0002302132 scopus 로고    scopus 로고
    • Adrenocorticotropic hormone; adrenocortical steroids and their synthetic analogs; inhibitors of the synthesis and actions of adrenocortical hormones
    • 10th ed., J.G. Hardman, L.E. Limbird, and A.G. Gilman, Eds. McGraw-Hill, New York, NY
    • B.P. Schimmer and K.L. Parker. Adrenocorticotropic hormone; adrenocortical steroids and their synthetic analogs; inhibitors of the synthesis and actions of adrenocortical hormones. In Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10th ed., J.G. Hardman, L.E. Limbird, and A.G. Gilman, Eds. McGraw-Hill, New York, NY, 2001, pp 1649-1677.
    • (2001) Goodman and Gilman's The Pharmacological Basis of Therapeutics , pp. 1649-1677
    • Schimmer, B.P.1    Parker, K.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.