메뉴 건너뛰기




Volumn 23, Issue 9, 2001, Pages 1355-1390

A review of the chemistry, biological action, and clinical applications of anabolic-androgenic steroids

Author keywords

Anabolic steroids; Anabolic androgenic steroids; Testosterone

Indexed keywords

2,3 DIPHOSPHOGLYCERIC ACID; 5BETA ANDROSTANOLONE; ALKALINE PHOSPHATASE; ANABOLIC AGENT; ANDROSTANOLONE; ANDROSTENEDIONE; ANDROSTERONE; ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; BUTADIENE DIEPOXIDE; COMPLEMENT COMPONENT C1S; CREATINE KINASE; ERYTHROPOIETIN; ESTRADIOL; ETIOCHOLANOLONE; KETOTIFEN; LYMPHOCYTE ANTIBODY; MITOMYCIN C; NANDROLONE; NANDROLONE DECANOATE; OXANDROLONE; OXYMETHOLONE; RECOMBINANT ERYTHROPOIETIN; STANOZOLOL; STEROID 5ALPHA REDUCTASE; TESTOSTERONE; TESTOSTERONE DERIVATIVE; THYMOCYTE ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 0034811303     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/S0149-2918(01)80114-4     Document Type: Article
Times cited : (374)

References (239)
  • 6
  • 7
    • 0021333344 scopus 로고
    • Anabolic steroids in athletics: How well do they work and how dangerous are they?
    • (1984) Am J Sports Med , vol.12 , pp. 31-38
    • Lamb, D.R.1
  • 20
    • 0026603787 scopus 로고
    • Anabolic-androgenic steroids and psychiatric-related effects: A review
    • (1992) Can J Psychiatry , vol.37 , pp. 23-28
    • Uzych, L.1
  • 25
    • 0028578089 scopus 로고
    • Weight training. A potential confounding factor in examining the psychological and behavioural effects of anabolic-androgenic steroids
    • (1994) Sports Med , vol.18 , pp. 309-318
    • Bahrke, M.S.1    Yesalis III, C.E.2
  • 29
    • 0030968670 scopus 로고    scopus 로고
    • Adolescents anabolic steroids: A subject review
    • (1997) Pediatrics , vol.99 , pp. 904-908
  • 32
    • 0020470292 scopus 로고
    • The 5α-reduction of testosterone in the neuroendocrine structures. Biochemical and physiological implications
    • (1982) Endocr Rev , vol.3 , pp. 1-25
    • Martini, L.1
  • 35
    • 0011039106 scopus 로고
    • 4-reductase. Their physiological role and significance
    • Hobkirk R, ed. Boca Raton, Fla: CRC Press
    • (1979) Steroid Biochemistry , vol.1 , pp. 1-27
    • Clark, A.F.1
  • 36
    • 84982341740 scopus 로고
    • Sexualhormone X herstellung des 17-methyltestosteron und anderer androsten und androstanderivate. Zusammenhänge zwischen chemischer konstitution und männlicher hormonwirkung
    • (1935) Helv Chim Acta , vol.18 , pp. 1487-1498
    • Ruzicka, L.1    Goldberg, M.W.2    Rosenberg, H.R.3
  • 45
    • 0026795638 scopus 로고
    • Studies on anabolic steroids. 10. Synthesis and identification of acidic urinary metabolites of oxymetholone in a human
    • (1992) Steroids , vol.57 , pp. 453-459
    • Bi, H.1    Masse, R.2    Just, G.3
  • 50
    • 0001547851 scopus 로고
    • The relationship of synthetic male hormone, androstenedione, to the protein and energy metabolism of castrate dogs and the protein metabolism of a normal dog
    • (1936) Am J Physiol , vol.117 , pp. 642-657
    • Kochakian, C.D.1    Murlin, J.R.2
  • 51
    • 0003412095 scopus 로고
    • Testosterone and testosterone acetate and the protein and energy metabolism of castrate dogs
    • (1937) Endocrinology , vol.21 , pp. 750-755
    • Kochakian, C.D.1
  • 60
    • 0017119763 scopus 로고
    • Characterization of the androgen receptors in the skeletal muscle of the rat
    • (1976) Steroids , vol.28 , pp. 261-274
    • Krieg, M.1
  • 63
    • 0021233846 scopus 로고
    • Relative binding affinity of anabolicandrogenic steroids: Comparison of the binding to the androgen receptors in skeletal muscle and prostate as well as to sex hormone-binding globulin
    • (1984) Endocrinology , vol.114 , pp. 2100-2106
    • Saartok, T.1    Dahlberg, E.2    Gustafsson, J.A.3
  • 65
    • 0018945612 scopus 로고
    • In vitro metabolism of 5α-dihydrotestosterone to 5α-androstane-3α, 17β-3-diol in rat heart, diaphragm, skeletal muscle and bulbocavernous/levator ani: Enzyme characterization and quantification
    • (1980) J Steroid Biochem , vol.13 , pp. 917-924
    • Smith, K.1    Krieg, M.2    Schwien, S.3
  • 67
    • 0030851537 scopus 로고    scopus 로고
    • Endocrine aspects of anabolic steroids
    • (1997) Clin Chem , vol.43 , pp. 1289-1292
    • Wu, F.C.1
  • 69
    • 76549242887 scopus 로고
    • Comparison of protein anabolic property of various androgens in the castrated rat
    • (1950) Am J Physiol , vol.160 , pp. 53-67
    • Kochakian, C.D.1
  • 75
    • 0015746560 scopus 로고
    • The effects of an anabolic steroid on the strength, body composition, and endurance of college males when accompanied by a weight training program
    • (1973) Med Sci Sports , vol.5 , pp. 272-276
    • Fahey, T.D.1    Brown, C.H.2
  • 87
    • 0003364641 scopus 로고
    • The effects of castration and cryptorchidization on the blood picture of the golden hamster
    • Abstract
    • (1944) Anat Rec , vol.88 , pp. 459
    • Stein, K.1    Jacobsen, B.2
  • 89
    • 0000142056 scopus 로고
    • Effects of hypophysectomy, castration, and testosterone propionate on hemopoiesis in the adult male rat
    • (1946) Endocrinology , vol.39 , pp. 401-413
    • Crafts, R.C.1
  • 90
    • 0000552980 scopus 로고
    • Influence of age and sex on hemoglobin: A spectrophotometric analysis of nine hundred and nineteen cases
    • (1916) Arch Intern Med , vol.18 , pp. 505-528
    • Williamson, C.S.1
  • 92
    • 0001547654 scopus 로고
    • The cause of the sexual differences in erythrocyte, hemoglobin and serum iron levels in human adults
    • (1950) Blood , vol.5 , pp. 874-875
    • Vahlquist, B.1
  • 103
    • 0013914798 scopus 로고
    • Inhibition of erythropoietic stimulation by testosterone in polycythemic mice receiving anti-erythropoietin
    • (1966) Proc Soc Exp Biol Med , vol.122 , pp. 402-403
    • Schooley, J.C.1
  • 105
    • 0014493270 scopus 로고
    • Erythropoietin and erythropoiesis in anemic man following androgens
    • (1969) Blood , vol.33 , pp. 564-572
    • Alexanian, R.1
  • 109
  • 112
    • 0013902521 scopus 로고
    • Tissue culture of bone marrow. II. Effect of steroid hormones on hematopoiesis in vitro
    • (1966) Blood , vol.27 , pp. 460-469
    • Reisner E.H., Jr.1
  • 113
    • 36949057192 scopus 로고
    • Effect of steroids on the cycling of haemopoietic stem cells
    • (1970) Nature , vol.228 , pp. 1204
    • Byron, J.W.1
  • 116
    • 0014574975 scopus 로고
    • Studies on the control of hemoglobin synthesis: The in vitro stimulating effect of a 5β-H steroid metabolite on heme formation in human bone marrow cells
    • (1969) Blood , vol.34 , pp. 380-384
    • Necheles, T.F.1    Rai, U.S.2
  • 119
    • 0016733331 scopus 로고
    • Effects of testosterone and erythropoietin on erythroid colony formation in human bone marrow cultures
    • (1975) Blood , vol.45 , pp. 665-670
    • Moriyama, Y.1    Fisher, J.W.2
  • 129
    • 0023008195 scopus 로고
    • Osteoporosis in hypogonadal men: Role of decreased plasma 1,25-dihydroxyvitamin D, calcium malabsorption, and low bone formation
    • (1986) Bone , vol.7 , pp. 261-268
    • Francis, R.M.1    Peacock, M.2    Aaron, J.E.3
  • 131
    • 0025881025 scopus 로고
    • High-affinity androgen binding and androgenic regulation of α1(I)-procollagen and transforming growth factor-β steady state messenger ribonucleic acid levels in human osteoblast-like osteosarcoma cells
    • (1991) Endocrinology , vol.128 , pp. 2723-2730
    • Benz, D.J.1    Haussler, M.R.2    Thomas, M.A.3
  • 132
    • 0025147679 scopus 로고
    • Effects of androgens on parathyroid hormone and interleukin-1-stimulated prostaglandin production in cultured neonatal mouse calvariae
    • (1990) J Bone Miner Res , vol.5 , pp. 1183-1188
    • Pilbeam, C.C.1    Raisz, L.G.2
  • 141
    • 0024448387 scopus 로고
    • Direct modulation by androgens of the response of human bone cells (SaOS-2) to human parathyroid hormone (PTH) and PTH-related protein
    • (1989) Endocrinology , vol.125 , pp. 1789-1794
    • Fukayama, S.1    Tashjian A.H., Jr.2
  • 145
    • 0029899784 scopus 로고    scopus 로고
    • Safety and efficacy of nandrolone decanoate for treatment of wasting in patients with HIV infection
    • (1996) AIDS , vol.10 , pp. 745-752
    • Gold, J.1    High, H.A.2    Li, Y.3
  • 146
    • 0033553201 scopus 로고    scopus 로고
    • Resistance exercise and supraphysiologic androgen therapy in eugonadal men with HIV-related weight loss: A randomized controlled trial
    • (1999) JAMA , vol.281 , pp. 1282-1290
    • Strawford, A.1    Barbieri, T.2    Van Loan, M.3
  • 154
    • 0032948205 scopus 로고    scopus 로고
    • Effect of oxymetholone on left ventricular dimensions in heart failure secondary to idiopathic dilated cardiomyopathy or to mitral or aortic regurgitation
    • (1999) Am J Cardiol , vol.83 , pp. 123-125
    • Tomoda, H.1
  • 155
    • 0032939334 scopus 로고    scopus 로고
    • Comparison of the anabolic effects and complications of human growth hormone and the testosterone analog, oxandrolone, after severe burn injury
    • (1999) Burns , vol.25 , pp. 215-221
    • Demling, R.H.1
  • 156
  • 157
    • 0027513259 scopus 로고
    • A study of oral nutritional support with oxandrolone in malnourished patients with alcoholic hepatitis: Results of a Department of Veterans Affairs cooperative study
    • (1993) Hepatology , vol.17 , pp. 564-576
    • Mendenhall, C.L.1    Moritz, T.E.2    Roselle, G.A.3
  • 159
    • 0028787913 scopus 로고
    • Growth promotion by oxandrolone in a girl with short stature and early pubertal development treated with growth hormone and gonadotropin-releasing hormone-analogue. A case study
    • (1995) Acta Paediatr , vol.84 , pp. 1207-1210
    • Hermanussen, M.1
  • 161
    • 0031051026 scopus 로고    scopus 로고
    • Growth promotion and Turner-specific bone age after therapy with growth hormone and in combination with oxandrolone: When should therapy be started in Turner syndrome?
    • (1997) Horm Res , vol.47 , pp. 102-109
    • Joss, E.E.1    Mullis, P.E.2    Werder, E.A.3
  • 164
    • 0000566055 scopus 로고
    • Testosterone-induced remission in aplastic anemia of both acquired and congenital types - Further observations in 24 cases
    • (1961) N Engl J Med , vol.264 , pp. 953-967
    • Shahidi, N.T.1    Diamond, L.K.2
  • 165
    • 0003416442 scopus 로고
    • Anemias caused by infection and toxins, idiopathic aplastic anemia and anemia caused by renal disease
    • (1957) Pediatr Clin North Am , pp. 469-480
    • Wolff, J.A.1
  • 170
    • 0021842458 scopus 로고
    • Do androgens enhance the response to antithymocyte globulin in patients with aplastic anemia? A prospective randomized trial
    • (1985) Blood , vol.66 , pp. 184-188
    • Champlin, R.E.1    Ho, W.G.2    Feig, S.A.3
  • 172
    • 0027396820 scopus 로고
    • Treatment of aplastic anemia (AA) with antilymphocyte globulin (ALG) and methylprednisolone (MPred) with or without androgens: A randomized trial from the EBMT SAA Working Party
    • (1993) Br J Haematol , vol.83 , pp. 145-151
    • Bacigalupo, A.1    Chaple, M.2    Hows, J.3
  • 181
    • 0022217573 scopus 로고
    • Hairy cell leukemia. Durability of response to splenectomy in 26 patients and treatment of relapse with androgens in six patients
    • (1985) Cancer , vol.56 , pp. 2557-2562
    • Magee, M.J.1    McKenzie, S.2    Filippa, D.A.3
  • 187
    • 85031488995 scopus 로고    scopus 로고
    • An eleven-year response of trisomy 8 myelodysplastic syndrome (MDS) to oxymetholone (OXYM)
    • Abstract 4497
    • (1999) Blood , vol.94 , pp. 2866
    • Perrotta, A.L.1    Abuel, C.2
  • 188
    • 0030843550 scopus 로고    scopus 로고
    • A 6-month study of low-dose recombinant human erythropoietin alone and in combination with androgens for the treatment of anemia in chronic hemodialysis patients
    • (1997) Am J Kidney Dis , vol.30 , pp. 495-500
    • Gaughan, W.J.1    Liss, K.A.2    Dunn, S.R.3
  • 190
    • 0026051481 scopus 로고
    • A randomized, controlled trial of treatment of alcoholic hepatitis with parenteral nutrition and oxandrolone. II. Short-term effects on nitrogen metabolism, metabolic balance, and nutrition
    • (1991) Am J Gastroenterol , vol.86 , pp. 1209-1218
    • Bonkovsky, H.L.1    Singh, R.H.2    Jafri, I.H.3
  • 192
    • 50549190821 scopus 로고
    • A biochemical abnormality in hereditary angioneurotic edema: Absence of serum inhibitor of C 1-esterase
    • (1963) Am J Med , vol.35 , pp. 37-44
    • Donaldson, V.H.1    Evans, R.R.2
  • 193
    • 0026645882 scopus 로고
    • Hereditary and acquired C 1-inhibitor deficiency: Biological and clinical characteristics in 235 patients
    • (1992) Medicine , vol.71 , pp. 206-215
    • Agostoni, A.1    Cicardi, M.2
  • 225
    • 0026473103 scopus 로고
    • Exuberant local tissue reaction to intramuscular injection of nandrolone decanoate (Deca-Durabolin) - A steroid compound in a sesame seed oil base - Mimicking soft tissue malignant tumors: A case report and review of the literature
    • (1992) Mil Med , vol.157 , pp. 670-674
    • Khankhanian, N.K.1    Hammers, Y.A.2    Kowalski, P.3
  • 228
    • 0025947444 scopus 로고
    • Atherogenic effect of anabolic steroids on serum lipid levels. A literature review
    • (1991) Arch Intern Med , vol.151 , pp. 1925-1933
    • Glazer, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.