메뉴 건너뛰기




Volumn 107, Issue 11, 1999, Pages 855-860

A yeast screen system for aromatase inhibitors and ligands for androgen receptor: Yeast cells transformed with aromatase and androgen receptor

Author keywords

Androgen receptor; Aromatase; Cytochrome P450; Endocrine disruptors; Yeast screening method

Indexed keywords

AMINOGLUTETHIMIDE; ANDROGEN; ANDROGEN RECEPTOR; ANDROSTENEDIONE; AROMATASE; AROMATASE INHIBITOR; BETA GALACTOSIDASE; CHRYSIN; CYTOCHROME P450; ENVIRONMENTAL CHEMICAL; FLAVONE DERIVATIVE; LIGAND; TESTOSTERONE;

EID: 0345201750     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.99107855     Document Type: Article
Times cited : (27)

References (30)
  • 1
    • 0023520433 scopus 로고
    • Estrogen formation in the mammalian brain: Possible role of aromatase in sexual differentiation of the hippocampus and neocortex
    • MacLusky NJ, Clark AS, Naftolin F, Goldman-Rakic PS. Estrogen formation in the mammalian brain: possible role of aromatase in sexual differentiation of the hippocampus and neocortex. Steroids 50:459-474 (1987).
    • (1987) Steroids , vol.50 , pp. 459-474
    • MacLusky, N.J.1    Clark, A.S.2    Naftolin, F.3    Goldman-Rakic, P.S.4
  • 2
    • 0023519279 scopus 로고
    • The importance of local synthesis of estrogen within the breast
    • Miller WR, O'Neill J. The importance of local synthesis of estrogen within the breast. Steroids 50:537-548 (1987).
    • (1987) Steroids , vol.50 , pp. 537-548
    • Miller, W.R.1    O'Neill, J.2
  • 4
    • 0024419217 scopus 로고
    • In situ oestrone synthesis in normal breast and breast tumor tissues: Effect of treatment with 4-hydroxyandrostenedione
    • Reed MJ, Owen AM, Lai LC, Coldham NG, Ghilchik MW, Shaikh NA, James VHT. In situ oestrone synthesis in normal breast and breast tumor tissues: effect of treatment with 4-hydroxyandrostenedione. Int J Cancer 44:233-237 (1989).
    • (1989) Int J Cancer , vol.44 , pp. 233-237
    • Reed, M.J.1    Owen, A.M.2    Lai, L.C.3    Coldham, N.G.4    Ghilchik, M.W.5    Shaikh, N.A.6    James, V.H.T.7
  • 5
    • 0017755181 scopus 로고
    • The effect of an aromatase inhibitor, 4-hydroxy-4-androstene-3,17-dione, on estrogen dependent processes in reproduction and breast cancer
    • Brodie AMH, Schwarzel WC, Shaikh AA, Brodie H. The effect of an aromatase inhibitor, 4-hydroxy-4-androstene-3,17-dione, on estrogen dependent processes in reproduction and breast cancer. Endocrinology 100:1684-1695 (1977).
    • (1977) Endocrinology , vol.100 , pp. 1684-1695
    • Brodie, A.M.H.1    Schwarzel, W.C.2    Shaikh, A.A.3    Brodie, H.4
  • 6
    • 0020325107 scopus 로고
    • Basic studies on aminoglutethimide
    • Salhanick HA. Basic studies on aminoglutethimide. Cancer Res 42 (suppl):S3315-S3321 (1982).
    • (1982) Cancer Res , vol.42 , Issue.SUPPL.
    • Salhanick, H.A.1
  • 9
    • 0031761935 scopus 로고    scopus 로고
    • Sexual differentiation and environmental endocrine disruptors
    • Toppari J, Skakkebaek NE. Sexual differentiation and environmental endocrine disruptors. Baillieres Clin Endocrinol Metab 12:143-156 (1998).
    • (1998) Baillieres Clin Endocrinol Metab , vol.12 , pp. 143-156
    • Toppari, J.1    Skakkebaek, N.E.2
  • 11
    • 0031878114 scopus 로고    scopus 로고
    • Antiandrogens as environmental endocrine disruptors
    • Kelce WR, Gray LE, Wilson EM. Antiandrogens as environmental endocrine disruptors. Reprod Fertil Dev 10:105-111 (1998).
    • (1998) Reprod Fertil Dev , vol.10 , pp. 105-111
    • Kelce, W.R.1    Gray, L.E.2    Wilson, E.M.3
  • 12
    • 0032052810 scopus 로고    scopus 로고
    • An updated review of environmental estrogen and androgen mimics and antagonists
    • Sonnenschein C, Soto AM. An updated review of environmental estrogen and androgen mimics and antagonists. J Steroid Biochem Mol Biol 65:143-150 (1998).
    • (1998) J Steroid Biochem Mol Biol , vol.65 , pp. 143-150
    • Sonnenschein, C.1    Soto, A.M.2
  • 13
    • 0031915796 scopus 로고    scopus 로고
    • Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study
    • Kao YC, Zhou C, Sherman M, Laughton CA, Chen S. Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: a site-directed mutagenesis study. Environ Health Perspect 106:85-92 (1998).
    • (1998) Environ Health Perspect , vol.106 , pp. 85-92
    • Kao, Y.C.1    Zhou, C.2    Sherman, M.3    Laughton, C.A.4    Chen, S.5
  • 14
    • 0021271612 scopus 로고
    • Inhibition of estrogen systhetase (aromatase) by flavones
    • Kellis JT, Vickery LE. Inhibition of estrogen systhetase (aromatase) by flavones. Science 225:1032-1034 (1984).
    • (1984) Science , vol.225 , pp. 1032-1034
    • Kellis, J.T.1    Vickery, L.E.2
  • 16
    • 0025089197 scopus 로고
    • Stable expression of human aromatase complementary DNA in mammalian cells: A useful system for aromatase inhibitor screening
    • Zhou D, Pompon D, Chen S. Stable expression of human aromatase complementary DNA in mammalian cells: a useful system for aromatase inhibitor screening. Cancer Res 50:6949-6954 (1990).
    • (1990) Cancer Res , vol.50 , pp. 6949-6954
    • Zhou, D.1    Pompon, D.2    Chen, S.3
  • 17
    • 0023091482 scopus 로고
    • Protease B of Saccharomyces cerevisiae: Isolation and regulation of the PRBI structural gene
    • Moehle CM, Ayanardi MW, Kolodny MR, Park FJ, Jones EW. Protease B of Saccharomyces cerevisiae: isolation and regulation of the PRBI structural gene. Genetics 115:255-263 (1987).
    • (1987) Genetics , vol.115 , pp. 255-263
    • Moehle, C.M.1    Ayanardi, M.W.2    Kolodny, M.R.3    Park, F.J.4    Jones, E.W.5
  • 18
    • 0024840348 scopus 로고
    • Expression of functional chicken progesterone receptor in yeast (Saccharomyces cerevisiae)
    • Mak P, McDonnell DP, Weigel NL, Schrader WT, O'Malley BW. Expression of functional chicken progesterone receptor in yeast (Saccharomyces cerevisiae). J Biol Chem 264:21613-21618 (1989).
    • (1989) J Biol Chem , vol.264 , pp. 21613-21618
    • Mak, P.1    McDonnell, D.P.2    Weigel, N.L.3    Schrader, W.T.4    O'Malley, B.W.5
  • 20
    • 0028120261 scopus 로고
    • A novel yeast expression system to study androgen action
    • Mak P, Young CYF, Tindall DJ. A novel yeast expression system to study androgen action. Recent Prog Horm Res 49:347-452 (1994).
    • (1994) Recent Prog Horm Res , vol.49 , pp. 347-452
    • Mak, P.1    Young, C.Y.F.2    Tindall, D.J.3
  • 21
    • 0024267319 scopus 로고
    • Steroid hormone-dependent interaction of human progesterone receptor with its target enhancer element
    • Bagchi MK, Elliston JF, Tsai SY, Edwards DP, Tsai MJ, O'Malley BW. Steroid hormone-dependent interaction of human progesterone receptor with its target enhancer element. Mol Endocrinol 2:1221-1229 (1988).
    • (1988) Mol Endocrinol , vol.2 , pp. 1221-1229
    • Bagchi, M.K.1    Elliston, J.F.2    Tsai, S.Y.3    Edwards, D.P.4    Tsai, M.J.5    O'Malley, B.W.6
  • 23
    • 0016293443 scopus 로고
    • Utilization of oxygen and reduced nicotinamide adenine dinucleotide phosphate by human placental microsomes during aromatization of androstenedione
    • Thompson EA Jr, Siiteri PK. Utilization of oxygen and reduced nicotinamide adenine dinucleotide phosphate by human placental microsomes during aromatization of androstenedione. J Biol Chem 249:5364-5372 (1974).
    • (1974) J Biol Chem , vol.249 , pp. 5364-5372
    • Thompson E.A., Jr.1    Siiteri, P.K.2
  • 24
    • 0028356656 scopus 로고
    • RXRα homodimers function as transcriptional activators in yeast
    • Mak P, Fuernkranz HA, Ge R, Karathanasis SK. RXRα homodimers function as transcriptional activators in yeast. Gene 145:129-133 (1994).
    • (1994) Gene , vol.145 , pp. 129-133
    • Mak, P.1    Fuernkranz, H.A.2    Ge, R.3    Karathanasis, S.K.4
  • 25
    • 0030003679 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the apoAI gene by retinoic acid receptor homo- and heterodimers in yeast
    • Salerno AJ, He Z, Goos-Nilsson A, Ahola H, Mak P. Differential transcriptional regulation of the apoAI gene by retinoic acid receptor homo- and heterodimers in yeast. Nucleic Acid Res 24:566-572 (1996).
    • (1996) Nucleic Acid Res , vol.24 , pp. 566-572
    • Salerno, A.J.1    He, Z.2    Goos-Nilsson, A.3    Ahola, H.4    Mak, P.5
  • 26
    • 0032803002 scopus 로고    scopus 로고
    • Functional characterization of 102-amino acid-deleted form of human aromatase
    • Kao YC, Higashiyama T, Yarborough C, Osawa Y, Chen S. Functional characterization of 102-amino acid-deleted form of human aromatase. Steroids 64:422-429 (1999).
    • (1999) Steroids , vol.64 , pp. 422-429
    • Kao, Y.C.1    Higashiyama, T.2    Yarborough, C.3    Osawa, Y.4    Chen, S.5
  • 27
    • 0025651532 scopus 로고
    • Clinical development of aromatase inhibitors for the treatment of breast and prostate cancer
    • Dowsett M. Clinical development of aromatase inhibitors for the treatment of breast and prostate cancer. J Steroid Biochem Mol Biol 37:1037-1041 (1990).
    • (1990) J Steroid Biochem Mol Biol , vol.37 , pp. 1037-1041
    • Dowsett, M.1
  • 28
    • 0026044429 scopus 로고
    • Aromatase and its inhibitors - An overview
    • Brodie A. Aromatase and its inhibitors - an overview. J Steroid Biochem Mol Biol 40:255-261 (1991).
    • (1991) J Steroid Biochem Mol Biol , vol.40 , pp. 255-261
    • Brodie, A.1
  • 29
    • 0028003744 scopus 로고
    • Second generation aromatase inhibitor - 4-hydroxyandrostenedione
    • Dowsett M, Coombes RC. Second generation aromatase inhibitor - 4-hydroxyandrostenedione. Breast Cancer Res Treat 30:81-87 (1994).
    • (1994) Breast Cancer Res Treat , vol.30 , pp. 81-87
    • Dowsett, M.1    Coombes, R.C.2
  • 30
    • 0026761588 scopus 로고
    • Effects of 4-hydroxyandrost-4-ene-3,17-dione and its metabolites on 5 alpha-reductase activity and androgen receptor
    • Davies JH, Shearer RJ, Rowlands MG, Poon GK, Houghton J, Jarman M, Dowsett M. Effects of 4-hydroxyandrost-4-ene-3,17-dione and its metabolites on 5 alpha-reductase activity and androgen receptor. J Enzyme Inhib 6:141-147 (1992).
    • (1992) J Enzyme Inhib , vol.6 , pp. 141-147
    • Davies, J.H.1    Shearer, R.J.2    Rowlands, M.G.3    Poon, G.K.4    Houghton, J.5    Jarman, M.6    Dowsett, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.