Competing clocks: Metabolic status moderates signals from the master circadian pacemaker

Neuroscience and Biobehavioral Reviews

Volumn 36, Issue 1, 2012, Pages 254-270

  Blum, I D ^a   Lamont, E Waddington ^a   Abizaid, A ^a  

^a CARLETON UNIVERSITY   (Canada)

Author keywords

Arousal; Circadian pacemaker; Circadian rhythms; Entrainment; Food anticipatory activity (FAA); Food entrainable oscillator (FEO); Light entrainable oscillator (LEO); Light dark cycle (LD); Suprachiasmatic nucleus (SCN)

Indexed keywords

NEUROPEPTIDE Y; PSYCHOTROPIC AGENT;

APPETITE; ASSOCIATION; BEHAVIOR THERAPY; BRAIN CELL; BRAIN DAMAGE; BRAIN METABOLISM; CALORIC INTAKE; CIRCADIAN RHYTHM; CLOCK GENE; DORSOMEDIAL HYPOTHALAMIC NUCLEUS; ENDOCRINOLOGY; FOOD AVAILABILITY; FOOD PREFERENCE; GENE; HOMEOSTASIS; HORMONE RESPONSE; HUMAN; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; LIGHT STRESS; MENTAL DISEASE; MOLECULAR BIOLOGY; MOLECULAR CLOCK; MOLECULAR GENETICS; NEUROANATOMY; NEUROBIOLOGY; NEUROENDOCRINE SYSTEM; NEUROMODULATION; NEUROPHYSIOLOGY; NONHUMAN; NUTRITIONAL STATUS; PHOTOSTIMULATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; RETINA; REVIEW; SIGNAL TRANSDUCTION; SUPRACHIASMATIC NUCLEUS; VISUAL MASKING; VISUAL STIMULATION; WORK SCHEDULE;

ANIMALS; AROUSAL; CIRCADIAN RHYTHM; FEEDING BEHAVIOR; HUMANS; NEURONS; SUPRACHIASMATIC NUCLEUS;

EID: 82855161429     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2011.06.003     Document Type: Review

References (256)

1. Abe H., Kida M., Tsuji K., Mano T. Feeding cycles entrain circadian rhythms of locomotor activity in CS mice but not in C57BL/6J mice. Physiol. Behav. 1989, 45:397-401.
2. Abraham U., Granada A.E., Westermark P.O., Heine M., Kramer A., Herzel H. Coupling governs entrainment range of circadian clocks. Mol. Syst. Biol. 2010, 6.
3. Acosta-Galvan G., Yi C.-X., van der Vliet J., Jhamandas J.H., Panula P., Angeles-Castellanos M., del Carmen Basualdo M., Escobar C., Buijs R.M. Interaction between hypothalamic dorsomedial nucleus and the suprachiasmatic nucleus determines intensity of food anticipatory behavior. Proc. Natl. Acad. Sci. 2011.
4. Acosta-Galvin G., Herrera D., Chao M., Escobar-Briones C., Buijs R.M. Importance of the interaction between the dorsomedial hypothalamic nucleus and the suprachiasmatic nucleus for the expression of the food anticipatory activity. Proc. Soc. Res. Biol. Rhythms 2008, 20:199.
5. Akiyama M., Yuasa T., Hayasaka N., Horikawa K., Sakurai T., Shibata S. Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice. Eur. J. Neurosci. 2004, 20:3054-3062.
6. Amir S., Lamont E.W., Robinson B., Stewart J. A circadian rhythm in the expression of PERIOD2 protein reveals a novel SCN-controlled oscillator in the oval nucleus of the bed nucleus of the stria terminalis. J. Neurosci. 2004, 24:781-790.
7. Andrade J.P., Pereira P.A., Silva S.M., Sa S.I., Lukoyanov N.V. Timed hypocaloric food restriction alters the synthesis and expression of vasopressin and vasoactive intestinal peptide in the suprachiasmatic nucleus. Brain Res. 2004, 1022:226-233.
8. Angeles-Castellanos M., Aguilar-Roblero R., Escobar C. c-Fos expression in hypothalamic nuclei of food-entrained rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2004, 286:R158-R165.
9. Angeles-Castellanos M., Salgado-Delgado R., Rodriguez K., Buijs R.M., Escobar C. The suprachiasmatic nucleus participates in food entrainment: a lesion study. Neuroscience 2010, 165:1115-1126.
10. Antle M., Mistlberger R. Circadian clock resetting by sleep deprivation without exercise in the Syrian hamster. J. Neurosci. 2000, 20:9326-9332.
11. Aschoff J., von Goetz C. Masking of circadian activity rhythms in canaries by light and dark. J. Biol. Rhythms 1989, 4:29-38.
12. Aschoff J., Vongoetz C., Honma K. Restricted feeding in rats-effects of varying feeding cycles. Z. Tierpsychol. 1983, 63:91-111.
13. Barnes S., Whistler H.L., Hughes J., Woodruff G.N., Hunter J.C. Effect of cholecystokinin octapeptide on endogenous amino acid release from the rat ventromedial nucleus of the hypothalamus and striatum. J. Neurochem. 1991, 56:1409-1416.
14. Bartness T.J., Song C.K., Demas G.E. SCN efferents to peripheral tissues: implications for biological rhythms. J. Biol. Rhythms 2001, 16:196-204.
15. Beaule C., Houle L.M., Amir S. Expression profiles of PER2 immunoreactivity within the shell and core regions of the rat suprachiasmatic nucleus: lack of effect of photic entrainment and disruption by constant light. J. Mol. Neurosci. 2003, 21:133-147.
16. Bell-Pedersen D., Cassone V.M., Earnest D.J., Golden S.S., Hardin P.E., Thomas T.L., Zoran M.J. Circadian rhythms from multiple oscillators: lessons from diverse organisms. Nat. Rev. Genet. 2005, 6:544-556.
17. Bell-Pedersen D., Crosthwaite S.K., Lakin-Thomas P.L., Merrow M., Okland M. The neurospora circadian clock: simple or complex?. Philos. Trans. R. Soc. Lond. B Biol. Sci. 2001, 356:1697-1709.
18. Biello S.M., Golombek D.A., Harrington M.E. Neuropeptide Y and glutamate block each other's phase shifts in the suprachiasmatic nucleus in vitro. Neuroscience 1997, 77:1049-1057.
19. Biello S.M., Janik D., Mrosovsky N. Neuropeptide y and behaviorally induced phase shifts. Neuroscience 1994, 62:273-279.
20. Blum I.D., Patterson Z., Khazall R., Lamont E.W., Sleeman M.W., Horvath T.L., Abizaid A. Reduced anticipatory locomotor responses to scheduled meals in ghrelin receptor deficient mice. Neuroscience 2009, 164:351-359.
21. Bolles R.C., Stokes L.W. Rat's anticipation of diurnal and a-diurnal feeding. J. Comp. Physiol. Psychol. 1965, 60:290-294.
22. Boulos Z., Rosenwasser A.M., Terman M. Feeding schedules and the circadian organization of behavior in the rat. Behav. Brain Res. 1980, 1:39-66.
23. Buijs R.M., Hou Y.X., Shinn S., Renaud L.P. Ultrastructural evidence for intra- and extranuclear projections of GABAergic neurons of the suprachiasmatic nucleus. J. Comp. Neurol. 1994, 340:381-391.
24. Buijs R.M., Kalsbeek A. Hypothalamic integration of central and peripheral clocks. Nat. Rev. Neurosci. 2001, 2:521-526.
25. Buijs R.M., Wortel J., Van Heerikhuize J.J., Feenstra M.G., Ter Horst G.J., Romijn H.J., Kalsbeek A. Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway. Eur. J. Neurosci. 1999, 11:1535-1544.
26. Canabal D.D., Song Z., Potian J.G., Beuve A., McArdle J.J., Routh V.H. Glucose, insulin, and leptin signaling pathways modulate nitric oxide synthesis in glucose-inhibited neurons in the ventromedial hypothalamus. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 292:R1418-R1428.
27. Canteras N.S., Simerly R.B., Swanson L.W. Organization of projections from the ventromedial nucleus of the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat. J. Comp. Neurol. 1994, 348:41-79.
28. Carneiro B.T.S., Araujo J.F. The Food-entrainable Oscillator: a network of interconnected brain structures entrained by humoral signals?. Chronobiol. Int. 2009, 26:1273-1289.
29. Castillo M.R., Hochstetler K.J., Tavernier R.J., Greene D.M., Bult-Ito A. Entrainment of the master circadian clock by scheduled feeding. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2004, 287:R551-R555.
30. Challet E. Interactions between light, mealtime and calorie restriction to control daily timing in mammals. J. Comp. Physiol. B: Biochem. Syst. Environ. Physiol. 2010, 180:631-644.
31. Challet E., Jacob N., Vuillez P., Pevet P., Malan A. Fos-like immunoreactivity in the circadian timing system of calorie-restricted rats fed at dawn: daily rhythms and light pulse-induced changes. Brain Res. 1997, 770:228-236.
32. Challet E., Le Maho Y., Pevet P., Nobelis P., Malan A. Ventromedial hypothalamic lesions prevent the fasting-induced changes in day-night pattern of locomotor activity. Behav. Brain Res. 1996, 77:155-163.
33. Challet E., Mendoza J., Dardente H., Pevet P. Neurogenetics of food anticipation. Eur. J. Neurosci. 2009, 30:1676-1687.
34. Challet E., Pevet P., Malan A. Intergeniculate leaflet lesion and daily rhythms in food-restricted rats fed during daytime. Neurosci. Lett. 1996, 216:214-218.
35. Chan J.L., Bullen J., Lee J.H., Yiannakouris N., Mantzoros C.S. Ghrelin levels are not regulated by recombinant leptin administration and/or three days of fasting in healthy subjects. J. Clin. Endocrinol. Metab. 2004, 89:335-343.
36. Chen X., Ge Y.L., Jiang Z.Y., Liu C.Q., Depoortere I., Peeters T.L. Effects of ghrelin on hypothalamic glucose responding neurons in rats. Brain Res. 2005, 1055:131-136.
37. Cheng M.Y., Bullock C.M., Li C., Lee A.G., Bermak J.C., Belluzzi J., Weaver D.R., Leslie F.M., Zhou Q.Y. Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus. Nature 2002, 417:405-410.
38. Choi S., Wong L.S., Yamat C., Dallman M.F. Hypothalamic ventromedial nuclei amplify circadian rhythms: do they contain a food-entrained endogenous oscillator?. J. Neurosci. 1998, 18:3843-3852.
39. Chou T.C., Bjorkum A.A., Gaus S.E., Lu J., Scammell T.E., Saper C.B. Afferents to the ventrolateral preoptic nucleus. J. Neurosci. 2002, 22:977-990.
40. Chou T.C., Scammell T.E., Gooley J.J., Gaus S.E., Saper C.B., Lu J. Critical role of dorsomedial hypothalamic nucleus in a wide range of behavioral circadian rhythms. J. Neurosci. 2003, 23:10691-10702.
41. Clifford S., Zeckler R.A., Buckman S., Thompson J., Hart N., Wellman P.J., Smith R.G. Impact of food restriction and cocaine on locomotion in ghrelin- and ghrelin-receptor knockout mice. Add. Biol. 2010.
42. Comperatore C.A., Stephan F.K. Effects of vagotomy on entrainment of activity rhythms to food access. Physiol. Behav. 1990, 47:671-678.
43. Csaki A., Kocsis K., Halasz B., Kiss J. Localization of glutamatergic/aspartatergic neurons projecting to the hypothalamic paraventricular nucleus studied by retrograde transport of [3H]D-aspartate autoradiography. Neuroscience 2000, 101:637-655.
44. Cui L.N., Coderre E., Renaud L.P. Glutamate and GABA mediate suprachiasmatic nucleus inputs to spinal-projecting paraventricular neurons. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2001, 281:R1283-R1289.
45. Cummings D.E., Purnell J.Q., Frayo R.S., Schmidova K., Wisse B.E., Weigle D.S. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001, 50:1714-1719.
46. Damiola F., Le Minh N., Preitner N., Kornmann B.ì.t., Fleury-Olela F., Schibler U. Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev. 2000, 14:2950-2961.
47. Dardente H. Synchronization and genetic redundancy in circadian clocks. Med. Sci. (Paris) 2008, 24:270-276.
48. Davidowa H., Li Y., Plagemann A. Differential response to NPY of PVH and dopamine-responsive VMH neurons in overweight rats. Neuroreport 2002, 13:1523-1527.
49. Davidson A.J. Lesion studies targeting food-anticipatory activity. Eur. J. Neurosci. 2009, 30:1658-1664.
50. Davidson A.J., Cappendijk S.L., Stephan F.K. Feeding-entrained circadian rhythms are attenuated by lesions of the parabrachial region in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000, 278:R1296-R1304.
51. Davidson A.J., Poole A.S., Yamazaki S., Menaker M. Is the food-entrainable circadian oscillator in the digestive system?. Genes Brain Behav. 2003, 2:32-39.
52. Davidson A.J., Stephan F.K. Circadian food anticipation persists in capsaicin deafferented rats. J. Biol. Rhythms 1998, 13:422-429.
53. Davis J.F., Choi D.L., Clegg D.J., Benoit S.C. Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice. Physiol. Behav. 2011, 103:39-43.
54. Deboer T., Vansteensel M.J., Detari L., Meijer J.H. Sleep states alter activity of suprachiasmatic nucleus neurons. Nat. Neurosci. 2003, 6:1086-1090.
55. Dhillon H., Zigman J.M., Ye C., Lee C.E., McGovern R.A., Tang V., Kenny C.D., Christiansen L.M., White R.D., Edelstein E.A., Coppari R., Balthasar N., Cowley M.A., Chua S., Elmquist J.K., Lowell B.B. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 2006, 49:191-203.
56. Dibner C., Schibler U., Albrecht U. The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Ann. Rev. Physiol. 2010, 72:517-549.
57. Drazen D.L., Vahl T.P., D'Alessio D.A., Seeley R.J., Woods S.C. Effects of a fixed meal pattern on ghrelin secretion: evidence for a learned response independent of nutrient status. Endocrinology 2006, 147:23-30.
58. Durgan D.J., Trexler N.A., Egbejimi O., McElfresh T.A., Suk H.Y., Petterson L.E., Shaw C.A., Hardin P.E., Bray M.S., Chandler M.P., Chow C.W., Young M.E. The circadian clock within the cardiomyocyte is essential for responsiveness of the heart to fatty acids. J. Biol. Chem. 2006, 281:24254-24269.
59. Edelstein K., Amir S. The intergeniculate leaflet does not mediate the disruptive effects of constant light on circadian rhythms in the rat. Neuroscience 1999, 90:1093-1101.
60. Edelstein K., Pfaus J.G., Rusak B., Amir S. Neonatal monosodium glutamate treatment prevents effects of constant light on circadian temperature rhythms of adult rats. Brain Res. 1995, 675:135-142.
61. Elde R., Hokfelt T., Johansson O., Terenius L. Immunohistochemical studies using antibodies to leucine-encephalin-initial observations on nervous-system of rat. Neuroscience 1976, 1. p. 349.
62. Elmquist J.K., Ahima R.S., Elias C.F., Flier J.S., Saper C.B. Leptin activates distinct projections from the dorsomedial and ventromedial hypothalamic nuclei. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:741-746.
63. Elmquist J.K., Elias C.F., Saper C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 1999, 22:221-232.
64. Escobar C., Cailotto C., Angeles-Castellanos M., Delgado R.S., Buijs R.M. Peripheral oscillators: the driving force for food-anticipatory activity. Eur. J. Neurosci. 2009, 30:1665-1675.
65. Escobar C., Martínez-Merlos M.T., Angeles-Castellanos M., Miñana M.D.C., Buijs R.M. Unpredictable feeding schedules unmask a system for daily resetting of behavioural and metabolic food entrainment. Eur. J. Neurosci. 2007, 26:2804-2814.
66. Evans J.A., Leise T.L., Castanon-Cervantes O., Davidson A.J. Intrinsic regulation of spatiotemporal organization within the suprachiasmatic nucleus. PLoS ONE 2011, 6:e15869.
67. Feillet C.A., Ripperger J.A., Magnone M.C., Dulloo A., Albrecht U., Challet E. Lack of food anticipation in Per2 mutant mice. Curr. Biol. 2006, 16:2016-2022.
68. Fite K., Janusonis S., Foote W., Bengston L. Retinal afferents to the dorsal raphe nucleus in rats and Mongolian gerbils. J. Comp. Neurol. 1999, 414:469-484.
69. Foote W.E., Taberpierce E., Edwards L. Evidence for a retinal projection to midbrain raphe of cat. Brain Res. 1978, 156:135-140.
70. Foster R., Provencio I., Hudson D., Fiske S., De Grip W., Menaker M. Circadian photoreception in the retinally degenerate mouse (rd/rd). J. Comp. Physiol. 1991, 169:39-50.
71. Fu L.Y., van den Pol A.N. Agouti-related peptide and MC3/4 receptor agonists both inhibit excitatory hypothalamic ventromedial nucleus neurons. J. Neurosci. 2008, 28:5433-5449.
72. Fuller P.M., Lu J., Saper C.B. Differential rescue of light- and food-entrainable circadian rhythms. Science 2008, 320:1074-1077.
73. Fuller P.M., Lu J., Saper C.B. Standards of evidence in chronobiology: a response. J. Circ. Rhythms 2009, 7:9.
74. Gahete M.D., Cordoba-Chacon J., Salvatori R., Castano J.P., Kineman R.D., Luque R.M. Metabolic regulation of ghrelin O-acyl transferase (GOAT) expression in the mouse hypothalamus, pituitary, and stomach. Mol. Cell. Endocrinol. 2010, 317:154-160.
75. Gamble K.L., Paul K.N., Tosini G., Albers H.E. Paradoxical effects of NPY in the suprachiasmatic nucleus. Eur. J. Neurosci. 2006, 23:2488-2494.
76. Gerkema M.P., Van der Zee E.A., Feitsma L.E. Expression of circadian rhythmicity correlates with the number of arginine-vasopressin-immunoreactive cells in the suprachiasmatic nucleus of common voles Microtus arvalis. Brain Res. 1994, 639:93-101.
77. Ginty D.D., Kornhauser J.M., Thompson M.A., Bading H., Mayo K.E., Takahashi J.S., Greenberg M.E. Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock. Science 1993, 260:238-241.
78. Golombek D.A., Rosenstein R.E. Physiology of circadian entrainment. Physiol. Rev. 2010, 90:1063-1102.
79. Gooley J., Lu J., Chou T., Scammell T., Saper C. Melanopsin in cells of origin of the retinohypothalamic tract. Nat. Neurosci. 2001, 4:1165.
80. Gooley J., Schomer A., Saper C. The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms. Nat. Neurosci. 2006, 9:398-407.
81. Gooley J.J., Saper C.B. Is food-directed behavior an appropriate measure of circadian entrainment to restricted daytime feeding?. J. Biol. Rhythms 2007, 22:479-483.
82. Gooley J.J., Schomer A., Saper C.B. The dorsomedial hypothalamic nucleus is critical for the expression of food-entrainable circadian rhythms. Nat. Neurosci. 2006, 9:398-407.
83. Guan X.M., Yu H., Palyha O.C., McKee K.K., Feighner S.D., Sirinathsinghji D.J., Smith R.G., Van der Ploeg L.H., Howard A.D. Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues. Brain Res. Mol. Brain Res. 1997, 48:23-29.
84. Guillaumond F., Dardente H., Giguere V., Cermakian N. Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors. J. Biol. Rhythms 2005, 20:391-403.
85. Guler A.D., Ecker J.L., Lall G.S., Haq S., Altimus C.M., Liao H.-W., Barnard A.R., Cahill H., Badea T.C., Zhao H., Hankins M.W., Berson D.M., Lucas R.J., Yau K.-W., Hattar S. Melanopsin cells are the principal conduits for rod-cone input to non-image-forming vision. Nature 2008, 453:102-105.
86. Hahn T.M., Breininger J.F., Baskin D.G., Schwartz M.W. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons. Nat. Neurosci. 1998, 1:271-272.
87. Hannibal J., Fahrenkrug J. Target areas innervated by PACAP-immunoreactive retinal ganglion cells. Cell Tissue Res. 2004, 316:99-113.
88. Hannibal J., Hindersson P., Knudsen S.M., Georg B., Fahrenkrug J. The photopigment melanopsin is exclusively present in pituitary adenylate cyclase-activating polypeptide-containing retinal ganglion cells of the retinohypothalamic tract. J. Neurosci. 2002, 22:RC191.
89. Hannibal J., Hindersson P., Ostergaard J., Georg B., Heegaard S., Larsen P.J., Fahrenkrug J. Melanopsin is expressed in PACAP-containing retinal ganglion cells of the human retinohypothalamic tract. Invest. Ophthalmol. Vis. Sci. 2004, 45:4202-4209.
90. Hara R., Wan K., Wakamatsu H., Aida R., Moriya T., Akiyama M., Shibata S. Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus. Genes Cells 2001, 6:269-278.
91. Harrington M.E., Nance D.M., Rusak B. Double-labeling of neuropeptide Y-immunoreactive neurons which project from the geniculate to the suprachiasmatic nuclei. Brain Res. 1987, 410:275-282.
92. Hastings M.H., Reddy A.B., Maywood E.S. A clockwork web: circadian timing in brain and periphery, in health and disease. Nat. Rev. Neurosci. 2003, 4:649-661.
93. Hattar S., Liao H.-W., Takao M., Berson D.M., Yau K.-W. Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity. Science 2002, 295:1065-1070.
94. Hattar S., Lucas R., Mrosovsky N., Thompson S., Douglas R., Hankins M., Lem J., Biel M., Hofmann F., Foster R., Yau K. Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice. Nature 2003, 424:76-81.
95. Hendrickson A.E., Wagoner N., Cowan W.M. An autoradiographic and electron microscopic study of retino-hypothalamic connections. Z. Zellforsch. Mikrosk Anat. 1972, 135:1-26.
96. Hermes M.L., Buijs R.M., Renaud L.P. Electrophysiology of suprachiasmatic nucleus projections to hypothalamic paraventricular nucleus neurons. Prog. Brain Res. 1996, 111:241-252.
97. Hermes M.L., Coderre E.M., Buijs R.M., Renaud L.P. GABA and glutamate mediate rapid neurotransmission from suprachiasmatic nucleus to hypothalamic paraventricular nucleus in rat. J. Physiol. 1996, 496(Pt 3):749-757.
98. Hermes M.L., Ruijter J.M., Klop A., Buijs R.M., Renaud L.P. Vasopressin increases GABAergic inhibition of rat hypothalamic paraventricular nucleus neurons in vitro. J. Neurophysiol. 2000, 83:705-711.
99. Hiler D.J., Bhattacherjee A., Yamazaki S., Tei H., Geusz M.E. Circadian mPer1 gene expression in mesencephalic trigeminal nucleus cultures. Brain Res. 2008, 1214:84-93.
100. Hokfelt T., Elde R., Johansson O., Terenius L., Stein L. Distribution of encephalin-immunoreactive cell bodies in rat central nervous-system. Neurosci. Lett. 1977, 5:25-31.
101. Honma K.I., Vongoetz C., Aschoff J. Effects of restricted daily feeding on freerunning circadian-rhythms in rats. Physiol. Behav. 1983, 30:905-913.
102. Honma S., Nakamura W., Shirakawa T., Honma K. Diversity in the circadian periods of single neurons of the rat suprachiasmatic nucleus depends on nuclear structure and intrinsic period. Neurosci. Lett. 2004, 358:173-176.
103. Huang X.F., Yu Y., Li Y., Tim S., Deng C., Wang Q. Ventromedial hypothalamic NPY Y2 receptor in the maintenance of body weight in diet-induced obesity in mice. Neurochem. Res. 2008, 33:1881-1888.
104. Ida T., Mori K., Miyazato M., Egi Y., Abe S., Nakahara K., Nishihara M., Kangawa K., Murakami N. Neuromedin s is a novel anorexigenic hormone. Endocrinology 2005, 146:4217-4223.
105. Ingram C.D., Snowball R.K., Mihai R. Circadian rhythm of neuronal activity in suprachiasmatic nucleus slices from the vasopressin-deficient Brattleboro rat. Neuroscience 1996, 75:635-641.
106. Inhoff T., Wiedenmann B., Klapp B.F., Mönnikes H., Kobelt P. Is desacyl ghrelin a modulator of food intake?. Peptides 2009, 30:991-994.
107. Inouye S.T. Restricted daily feeding does not entrain circadian rhythms of the suprachiasmatic nucleus in the rat. Brain Res. 1982, 232:194-199.
108. Inouye S.T. Ventromedial hypothalamic lesions eliminate anticipatory activities of restricted daily feeding schedules in the rat. Brain Res. 1982, 250:183-187.
109. Inouye S.T., Kawamura H. Persistence of circadian rhythmicity in a mammalian hypothalamic " island" containing the suprachiasmatic nucleus. Proc. Natl. Acad. Sci. U.S.A. 1979, 76:5962-5966.
110. Isobe Y., Nishino H. AVP rhythm in the suprachiasmatic nucleus in relation to locomotor activity under constant light. Peptides 1998, 19:827-832.
111. Janusonis S., Fite K.V., Bengston L. Subdivisions of the dorsal raphe nucleus projecting to the lateral geniculate nucleus and primary visual cortex in the Mongolian gerbil. Neuroreport 2003, 14:459-462.
112. Kakui N., Kitamura K. Direct evidence that stimulation of neuropeptide Y Y5 receptor activates hypothalamo-pituitary-adrenal axis in conscious rats via both corticotropin-releasing factor- and arginine vasopressin-dependent pathway. Endocrinology 2007, 148:2854-2862.
113. Kallingal G.J., Mintz E.M. Gastrin releasing peptide and neuropeptide Y exert opposing actions on circadian phase. Neurosci. Lett. 2007, 422:59-63.
114. Kalsbeek A., Buijs R.M., van Heerikhuize J.J., Arts M., van der Woude T.P. Vasopressin-containing neurons of the suprachiasmatic nuclei inhibit corticosterone release. Brain Res. 1992, 580:62-67.
115. Kalsbeek A., Fliers E., Franke A.N., Wortel J., Buijs R.M. Functional connections between the suprachiasmatic nucleus and the thyroid gland as revealed by lesioning and viral tracing techniques in the rat. Endocrinology 2000, 141:3832-3841.
116. Kalsbeek A., Fliers E., Hofman M.A., Swaab D.F., Buijs R.M. Vasopressin and the output of the hypothalamic biological clock. J. Neuroendocrinol. 2010, 22:362-372.
117. Kalsbeek A., Palm I.F., La Fleur S.E., Scheer F.A., Perreau-Lenz S., Ruiter M., Kreier F., Cailotto C., Buijs R.M. SCN outputs and the hypothalamic balance of life. J. Biol. Rhythms 2006, 21:458-469.
118. Kalsbeek A., van der Vliet J., Buijs R.M. Decrease of endogenous vasopressin release necessary for expression of the circadian rise in plasma corticosterone: a reverse microdialysis study. J. Neuroendocrinol. 1996, 8:299-307.
119. Kalsbeek A., van Heerikhuize J.J., Wortel J., Buijs R.M. A diurnal rhythm of stimulatory input to the hypothalamo-pituitary-adrenal system as revealed by timed intrahypothalamic administration of the vasopressin V1 antagonist. J. Neurosci. 1996, 16:5555-5565.
120. Kalsbeek A., van Heerikhuize J.J., Wortel J., Buijs R.M. Restricted daytime feeding modifies suprachiasmatic nucleus vasopressin release in rats. J. Biol. Rhythms 1998, 13:18-29.
121. Kamegai J., Tamura H., Shimizu T., Ishii S., Sugihara H., Wakabayashi I. Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in rats. Diabetes 2001, 50:2438-2443.
122. Kita H., Shibata S., Oomura Y., Ohki K. Excitatory effects of the suprachiasmatic nucleus on the ventromedial nucleus in the rat hypothalamic slice. Brain Res. 1982, 235:137-141.
123. Ko C.H., Takahashi J.S. Molecular components of the mammalian circadian clock. Hum. Mol. Genet. 2006, 15(Spec No. 2):R271-R277.
124. Kornmann B., Schaad O., Reinke H., Saini C., Schibler U. Regulation of circadian gene expression in liver by systemic signals and hepatocyte oscillators. Cold Spring Harbor Symposia on Quantitative Biology, vol. 72 2007, 319-330.
125. Kramer A., Yang F.C., Snodgrass P., Li X., Scammell T.E., Davis F.C., Weitz C.J. Regulation of daily locomotor activity and sleep by hypothalamic EGF receptor signaling. Science 2001, 294:2511-2515.
126. Kraves S., Weitz C.J. A role for cardiotrophin-like cytokine in the circadian control of mammalian locomotor activity. Nat. Neurosci. 2006, 9:212-219.
127. Krieger D.T. Ventromedial hypothalamic lesions abolish food-shifted circadian adrenal and temperature rhythmicity. Endocrinology 1980, 106:649-654.
128. Krout K.E., Kawano J., Mettenleiter T.C., Loewy A.D. CNS inputs to the suprachiasmatic nucleus of the rat. Neuroscience 2002, 110:73-92.
129. Kubota A., Inouye S.-I.T., Kawamura H. Reversal of multiunit activity within and outside the suprachiasmatic nucleus in the rat. Neurosci. Lett. 1981, 27:303-308.
130. Lamia K.A., Storch K.F., Weitz C.J. Physiological significance of a peripheral tissue circadian clock. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:15172-15177.
131. Landry G.J., Mear R.J., Mistlberger R.E. Surprisingly weak effect of sex as a zeitgeber in male rats. Society for Research on Biological Rhythms Biennial Meeting 2008.
132. Landry G.J., Patton D.F., Jaholkowski M., Kent B.A., Mistlberger R.E. A role for the dorsomedial hypothalamic nucleus in food anticipatory rhythms in rats 2010, Society for Research on Biological Rhythms, Florida, p. 46.
133. Landry G.J., Simon M.M., Webb I.C., Mistlberger R.E. Persistence of a behavioral food-anticipatory circadian rhythm following dorsomedial hypothalamic ablation in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006, 290:R1527-R1534.
134. Landry G.J., Yamakawa G.R., Webb I.C., Mear R.J., Mistlberger R.E. The dorsomedial hypothalamic nucleus is not necessary for the expression of circadian food-anticipatory activity in rats. J. Biol. Rhythms 2007, 22:467-478.
135. Lax P., Zamora S., Madrid J.A. Food-entrained feeding and locomotor circadian rhythms in rats under different lighting conditions. Chronobiol. Int. 1999, 16:281-291.
136. Lee J.G., Choi I.S., Park E.J., Cho J.H., Lee M.G., Choi B.J., Jang I.S. beta(2)-Adrenoceptor-mediated facilitation of glutamatergic transmission in rat ventromedial hypothalamic neurons. Neuroscience 2007, 144:1255-1265.
137. Lesauter J., Hoque N., Weintraub M., Pfaff D.W., Silver R. Stomach ghrelin-secreting cells as food-entrainable circadian clocks. Proc. Natl. Acad. Sci. U.S.A. 2009.
138. Liu J., Prudom C.E., Nass R., Pezzoli S.S., Oliveri M.C., Johnson M.L., Veldhuis P., Gordon D.A., Howard A.D., Witcher D.R., Geysen H.M., Gaylinn B.D., Thorner M.O. Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men. J. Clin. Endocrinol. Metab. 2008, 93:1980-1987.
139. Marchant E.G., Mistlberger R.E. Anticipation and entrainment to feeding time in intact and SCN-ablated C57BL/6j mice. Brain Res. 1997, 765:273-282.
140. Meijer J. Photic entrainment of mammals. Handbook of Behavioral Neurobiology. Circadian Clocks 2001, 183-222. Kluver Academic/Plenum. J.S. Takahashi, F.W. Turek, R.Y. Moore (Eds.).
141. Mendoza J., Albrecht U., Challet E. Behavioural food anticipation in clock genes deficient mice: confirming old phenotypes, describing new phenotypes. Genes Brain Behav. 2010.
142. Mendoza J., Angeles-Castellanos M., Escobar C. A daily palatable meal without food deprivation entrains the suprachiasmatic nucleus of rats. Euro. J. Neurosci. 2005, 22:2855-2862.
143. Mendoza J., Clesse D., Pévet P., Challet E. Food-reward signalling in the suprachiasmatic clock. J. Neurochem. 2010, 9999.
144. Mendoza J., Drevet K., Pevet P., Challet E. Daily meal timing is not necessary for resetting the main circadian clock by calorie restriction. J. Neuroendocrinol. 2008, 20:251-260.
145. Mendoza J., Pevet P., Challet E. High-fat feeding alters the clock synchronization to light. J. Physiol. 2008, 586:5901-5910.
146. Mieda M., Williams S.C., Richardson J.A., Tanaka K., Yanagisawa M. The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:12150-12155.
147. Mihai R., Coculescu M., Wakerley J.B., Ingram C.D. The effects of [Arg8]vasopressin and [Arg8]vasotocin on the firing rate of suprachiasmatic neurons in vitro. Neuroscience 1994, 62:783-792.
148. Mikkelsen J., Larsen P., Mick G., Vrang N., Ebling F., Maywood E., Hastings M., Moller M. Gating of retinal inputs through the suprachiasmatic nucleus: role of excitatory neurotransmission. Neurochem. Int. 1992, 27:263-272.
149. Mikkelsen J., Vrang N., Mrosovsky N. Expression of Fos in the circadian system following nonphotic stimulation. Brain Res. Bull. 1998, 47:367-376.
150. Mikkelsen J.D., Moller M. A direct neural projection from the intergeniculate leaflet of the lateral geniculate nucleus to the deep pineal gland of the rat, demonstrated with Phaseolus vulgaris leucoagglutinin. Brain Res. 1990, 520:342-346.
151. Mistlberger R.E. Effects of scheduled food and water access on circadian rhythms of hamsters in constant light, dark, and light:dark. Physiol. Behav. 1993, 53:509-516.
152. Mistlberger R.E. Circadian food-anticipatory activity: formal models and physiological mechanisms. Neurosci. Biobehav. Rev. 1994, 18:171-195.
153. Mistlberger R.E. Circadian rhythms: PERturbing a food-entrained clock. Curr. Biol. 2006, 16:R968-R969.
154. Mistlberger R.E. Food-anticipatory circadian rhythms: concepts and methods. Eur. J. Neurosci. 2009, 30:1718-1729.
155. Mistlberger R.E., Buijs R., Challet E., Escobar C., Landry G., Kalsbeek A., Pevet P., Shibata S. Food anticipation in Bmal1-/- and AAV-Bmal1 rescued mice: a reply to Fuller et al. J. Circ. Rhythms 2009, 7:11.
156. Mistlberger R.E., Buijs R.M., Challet E., Escobar C., Landry G.J., Kalsbeek A., Pevet P., Shibata S. Standards of evidence in chronobiology: Critical review of a report that restoration of Bmal1 expression in the dorsomedial hypothalamus is sufficient to restore circadian food anticipatory rhythms in Bmal1-/- mice. J. Circ. Rhythms 2009, 7:3.
157. Mistlberger R.E., Houpt T.A., Moore-Ede M.C. Characteristics of food-entrained orcadian rhythms in rats during long-term exposure to constant light. Chronobiol. Int. 1990, 7:383-391.
158. Mistlberger R.E., Marchant E.G. Computational and entrainment models of circadian food-anticipatory activity - evidence from non-24-Hr feeding schedules. Behav. Neurosci. 1995, 109:790-798.
159. Mistlberger R.E., Rechtschaffen A. Recovery of anticipatory activity to restricted feeding in rats with ventromedial hypothalamic lesions. Physiol. Behav. 1984, 33:227-235.
160. Mistlberger R.E., Skene D.J. Social influences on mammalian circadian rhythms: animal and human studies. Biol. Rev. 2004, 79:533-556.
161. Mistlberger R.E., Yamazaki S., Pendergast J.S., Landry G.J., Takumi T., Nakamura W. Comment on " Differential rescue of light- and food-entrainable circadian rhythms" Science 2008, 322:675.
162. Mitchell V., Bouret S., Beauvillain J.C., Schilling A., Perret M., Kordon C., Epelbaum J. Comparative distribution of mRNA encoding the growth hormone secretagogue-receptor (GHS-R) in Microcebus murinus (Primate, lemurian) and rat forebrain and pituitary. J. Comp. Neurol. 2001, 429:469-489.
163. Mobbs C.V., Kow L.M., Yang X.J. Brain glucose-sensing mechanisms: ubiquitous silencing by aglycemia vs. hypothalamic neuroendocrine responses. Am. J. Physiol. Endocrinol. Metab. 2001, 281:E649-E654.
164. Moga M.M., Moore R.Y. Organization of neural inputs to the suprachiasmatic nucleus in the rat. J. Comp. Neurol. 1997, 389:508-534.
165. Moore R.Y., Card J.P. Intergeniculate leaflet: an anatomically and functionally distinct subdivision of the lateral geniculate complex. J. Comp. Neurol. 1994, 344:403-430.
166. Moore R.Y., Lenn N.J. A retinohypothalamic projection in the rat. J. Comp. Neurol. 1972, 146:1-14.
167. Moore R.Y., Weis R., Moga M.M. Efferent projections of the intergeniculate leaflet and the ventral lateral geniculate nucleus in the rat. J. Comp. Neurol. 2000, 420:398-418.
168. Mori K., Miyazato M., Ida T., Murakami N., Serino R., Ueta Y., Kojima M., Kangawa K. Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J. 2005, 24:325-335.
169. Morin L.P., Allen C.N. The circadian visual system, 2005. Brain Res. Rev. 2006, 51:1-60.
170. Moriya T. The dorsomedial hypothalamic nucleus is not necessary for food-anticipatory circadian rhythms of behavior, temperature or clock gene expression in mice. Euro. J. Neurosci. 2009, 27:1447-1460.
171. Moriya T., Aida R., Kudo T., Akiyama M., Doi M., Hayasaka N., Nakahata N., Mistlberger R.E., Okamura H., Shibata S. The dorsomedial hypothalamic nucleus is not necessary for food-anticipatory circadian rhythms of behavior, temperature or clock gene expression in mice. Eur. J. Neurosci. 2009, 29:1447-1460.
172. Mrosovsky N. A non -photic gateway to the circadian clcok of hamsters. Circ. Clocks Adjust. 1995, 154-174.
173. Mrosovsky N. Locomotor activity and non-photic influences on circadian clocks. Biol. Rev. 1996, 71:343-372.
174. Mrosovsky N. Masking: History, definitions, and measurement. Chronobiol. Int. J. Biol. Med. Rhythm Res. 1999, 16:415-429.
175. Mrosovsky N., Foster R.G., Salmon P.A. Thresholds for masking responses to light in three strains of retinally degenerate mice. J. Comp. Physiol. A 1999, 184:423-428.
176. Mrosovsky N., Hattar S. Impaired masking responses to light in melanopsin-knockout mice. Chronobiol. Int. 2003, 20:989-999.
177. Muroya S., Funahashi H., Yamanaka A., Kohno D., Uramura K., Nambu T., Shibahara M., Kuramochi M., Takigawa M., Yanagisawa M., Sakurai T., Shioda S., Yada T. Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus. Eur. J. Neurosci. 2004, 19:1524-1534.
178. Murphy H.M., Wideman C.H., Nadzam G.R. The interaction of vasopressin and the photic oscillator in circadian rhythms. Peptides 1996, 17:467-475.
179. Murphy H.M., Wideman C.H., Nadzam G.R. The role of vasopressin in modulating circadian rhythm responses to phase shifts. Peptides 1998, 19:1191-1208.
180. Nakahata Y., Sahar S., Astarita G., Kaluzova M., Sassone-Corsi P. Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science 2009, 324:654-657.
181. Nakamura W., Yamazaki S., Nakamura T.J., Shirakawa T., Block G.D., Takumi T. In vivo monitoring of circadian timing in freely moving mice. Curr. Biol. 2008, 18:381-385.
182. Nixon J.P., Smale L. Orexin fibers form appositions with Fos expressing neuropeptide-Y cells in the grass rat intergeniculate leaflet. Brain Res. 2005, 1053:33-37.
183. Norgren R. Gustatory system. The Rat Nervous System 1995, 751-771. Academic Press, San Diego. G. Paxinos (Ed.).
184. O'Reilly H., Armstrong S.M., Coleman G.J. Restricted feeding and circadian activity rhythms of a predatory marsupial Dasyuroides byrnei. Physiol. Behav. 1986, 38:471-476.
185. Oster H., Damerow S., Kiessling S., Jakubcakova V., Abraham D., Tian J., Hoffmann M.W., Eichele G. The circadian rhythm of glucocorticoids is regulated by a gating mechanism residing in the adrenal cortical clock. Cell Metab. 2006, 4:163-173.
186. Panda S., Sato T., Castrucci A., Rollag M., DeGrip W., Hogenesch J., Provencio I., Kay S. Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting. Science 2002, 298:2213-2216.
187. Pendergast J.S., Nakamura W., Friday R.C., Hatanaka F., Takumi T., Yamazaki S. Robust food anticipatory activity in BMAL1-deficient mice. PLoS One 2009, 4:e4860.
188. Pitts S., Perone E., Silver R. Food-entrained circadian rhythms are sustained in arrhythmic Clk/Clk mutant mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003, 285:R57-R67.
189. Provencio I., Jiang G., De Grip W.J., Hayes W.P., Rollag M.D. Melanopsin: An opsin in melanophores, brain, and eye. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:340-345.
190. Redlin U. Neural basis and biological function of masking by light in mammals: Suppression of melatonin and locomotor activity. Chronobiol. Int. J. Biol. Med. Rhythm Res. 2001, 18:737-758.
191. Redlin U., Hattar S., Mrosovsky N. The circadian Clock mutant mouse: impaired masking response to light. J. Comp. Physiol. Neuroethol. Sens. Neural Behav Physiol 2005, 191:51-59.
192. Redlin U., Mrosovsky N. Masking by light in hamsters with SCN lesions. J. Comp. Physiol. A 1999, 184:439-448.
193. Reebs S.G., Mrosovsky N. Effects of induced wheel running on the circadian activity rhythms of syrian hamsters: entrainment and phase response curve. J. Biol. Rhythms 1989, 4:39-48.
194. Reghunandanan V., Reghunandanan R. Neurotransmitters of the suprachiasmatic nuclei. J. Circ. Rhythms 2006, 4:2.
195. Reid L.S., Finger F.W. The rat's adjustment to 23-hour food-deprivation cycles. J. Comp. Physiol. Psychol. 1955, 48:110-113.
196. Reppert S.M., Weaver D.R. Coordination of circadian timing in mammals. Nature 2002, 418:935-941.
197. Ribeiro A.C., LeSauter J., Dupre C., Pfaff D.W. Relationship of arousal to circadian anticipatory behavior: ventromedial hypothalamus: one node in a hunger-arousal network. Eur. J. Neurosci. 2009, 30:1730-1738.
198. Ricardo J.A., Koh E.T. Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat. Brain Res. 1978, 153:1-26.
199. Richter C.P. A behavioristic study of the activity of the rat. Comp. Psychol. Monogr. 1922, 1:1-54.
200. Rietveld W.J., Minors D.S., Waterhouse J.M. Circadian rhythms and masking: an overview. Chronobiol. Int. 1993, 10:306-312.
201. Rosenwasser A.M., Pelchat R.J., Adler N.T. Memory for feeding time: possible dependence on coupled circadian oscillators. Physiol. Behav. 1984, 32:25-30.
202. Rosenwasser A.M., Schulkin J., Adler N.T. Anticipatory appetitive behavior of adrenalectomized rats under circadian salt-access schedules. Anim. Learn Behav. 1988, 16:324-329.
203. Rusak B., Boulos Z. Pathways for photic entrainment of mammalian circadian rhythms. Photochem. Photobiol. 1981, 34:267-273.
204. Rusak B., Meijer J.H., Harrington M.E. Hamster circadian rhythms are phase-shifted by electrical stimulation of the geniculo-hypothalamic tract. Brain Res. 1989, 493:283-291.
205. Saper C.B., Loewy A.D. Efferent connections of the parabrachial nucleus in the rat. Brain Res. 1980, 197:291-317.
206. Saper C.B., Lu J., Chou T.C., Gooley J. The hypothalamic integrator for circadian rhythms. Trends Neurosci. 2005, 28:152-157.
207. Schaap J., Meijer J.H. Opposing effects of behavioural activity and light on neurons of the suprachiasmatic nucleus. Eur. J. Neurosci. 2001, 13:1955-1962.
208. Scott M.M., Lachey J.L., Sternson S.M., Lee C.E., Elias C.F., Friedman J.M., Elmquist J.K. Leptin targets in the mouse brain. J. Comp. Neurol. 2009, 514:518-532.
209. Selim M., Glass J.D., Hauser U.E., Rea M.A. Serotonergic inhibition of light-induced fos protein expression and extracellular glutamate in the suprachiasmatic nuclei. Brain Res. 1993, 621:181-188.
210. Sharma V.K., Chidambaram R., Subbaraj R., Chandrashekaran M.K. Effects of restricted feeding cycle on the locomotor activity rhythm in the mouse Mus booduga. Physiol. Behav. 2000, 70:81-87.
211. Shearman L.P., Sriram S., Weaver D.R., Maywood E.S., Chaves I., Zheng B., Kume K., Lee C.C., van der Horst G.T., Hastings M.H., Reppert S.M. Interacting molecular loops in the mammalian circadian clock. Science 2000, 288:1013-1019.
212. Shen H., Semba K. A direct retinal projection to the dorsal raphe nucleus in the rat. Brain Res. 1994, 635:159-168.
213. Silver R., LeSauter J., Tresco P.A., Lehman M.N. A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms. Nature 1996, 382:810-813.
214. Sim L.J., Joseph S.A. Arcuate nucleus projections to brainstem regions which modulate nociception. J. Chem. Neuroanat. 1991, 4:97-109.
215. Simerly R.B., Swanson L.W. The organization of neural inputs to the medial preoptic nucleus of the rat. J. Comp. Neurol. 1986, 246:312-342.
216. Skibicka K.P., Egecioglu E., Dickson S.L. Parabrachial nucleus is a new target of orexigenic action of ghrelin. Endocrine J. 2010, 57:S518-S1518.
217. Song Z., Routh V.H. Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus. Diabetes 2005, 54:15-22.
218. Stephan F.K. Phase shifts of circadian rhythms in activity entrained to food access. Physiol. Behav. 1984, 32:663-671.
219. Stephan F.K. Coupling between feeding- and light-entrainable circadian pacemakers in the rat. Physiol. Behav. 1986, 38:537-544.
220. Stephan F.K. The " other" circadian system: food as a Zeitgeber. J. Biol. Rhythms 2002, 17:284-292.
221. Stephan F.K., Swann J.M., Sisk C.L. Anticipation of 24-hr feeding schedules in rats with lesions of the suprachiasmatic nucleus. Behav. Neural. Biol. 1979, 25:346-363.
222. Stephan F.K., Swann J.M., Sisk C.L. Entrainment of circadian rhythms by feeding schedules in rats with suprachiasmatic lesions. Behav. Neural. Biol. 1979, 25:545-554.
223. Stokkan K.-A., Yamazaki S., Tei H., Sakaki Y., Menaker M. Entrainment of the Circadian Clock in the Liver by Feeding. Science 2001, 291:490-493.
224. Storch K.F., Paz C., Signorovitch J., Raviola E., Pawlyk B., Li T., Weitz C.J. Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information. Cell 2007, 130:730-741.
225. Storch K.F., Weitz C.J. Daily rhythms of food-anticipatory behavioral activity do not require the known circadian clock. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:6808-6813.
226. Sudo M., Sasahara K., Moriya T., Akiyama M., Hamada T., Shibata S. Constant light housing attenuates circadian rhythms of mPer2 mRNA and mPER2 protein expression in the suprachiasmatic nucleus of mice. Neuroscience 2003, 121:493-499.
227. Sutton G.M., Perez-Tilve D., Nogueiras R., Fang J., Kim J.K., Cone R.D., Gimble J.M., Tschop M.H., Butler A.A. The melanocortin-3 receptor is required for entrainment to meal intake. J. Neurosci. 2008, 28:12946-12955.
228. Tavakoli-Nezhad M., Schwartz W.J. c-Fos expression in the brains of behaviorally " split" hamsters in constant light: calling attention to a dorsolateral region of the suprachiasmatic nucleus and the medial division of the lateral habenula. J. Biol. Rhythms 2005, 20:419-429.
229. Teclemariam-Mesbah R., Ter Horst G.J., Postema F., Wortel J., Buijs R.M. Anatomical demonstration of the suprachiasmatic nucleus-pineal pathway. J. Comp. Neurol. 1999, 406:171-182.
230. Thompson R.H., Canteras N.S., Swanson L.W. Organization of projections from the dorsomedial nucleus of the hypothalamus: a PHA-L study in the rat. J. Comp. Neurol. 1996, 376:143-173.
231. Thompson R.H., Swanson L.W. Organization of inputs to the dorsomedial nucleus of the hypothalamus: a reexamination with Fluorogold and PHAL in the rat. Brain Res. Brain Res. Rev. 1998, 27:89-118.
232. Toshinai K., Yamaguchi H., Sun Y., Smith R.G., Yamanaka A., Sakurai T., Date Y., Mondal M.S., Shimbara T., Kawagoe T., Murakami N., Miyazato M., Kangawa K., Nakazato M. Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor. Endocrinology 2006, 147:2306-2314.
233. Tsuyoshi H., Naohiro K., Takashi I., Naosuke H., Toshiyuki O., Yoshitaka F. Transcriptional repressor TIEG1 regulates Bmal1 gene through GC box and controls circadian clockwork. Genes Cells 2010, 15:111-121.
234. Tups A., Helwig M., Khorooshi R.M., Archer Z.A., Klingenspor M., Mercer J.G. Circulating ghrelin levels and central ghrelin receptor expression are elevated in response to food deprivation in a seasonal mammal (Phodopus sungorus). J. Neuroendocrinol. 2004, 16:922-928.
235. Turek F.W. Circadian neural rhythms in mammals. Annu. Rev. Physiol. 1985, 47:49-64.
236. Uhl G.R., Goodman R.R., Snyder S.H. Neurotensin-containing cell-bodies, fibers and nerve-terminals in the brain-stem of the rat - immunohistochemical mapping. Brain Res. 1979, 167:77-91.
237. Verwey M., Khoja Z., Stewart J., Amir S. Differential regulation of the expression of Period2 protein in the limbic forebrain and dorsomedial hypothalamus by daily limited access to highly palatable food in food-deprived and free-fed rats. Neuroscience 2007, 147:277-285.
238. Verwey M., Lam G., Amir S. Circadian rhythms of PERIOD1 expression in the dorsomedial hypothalamic nucleus in the absence of entrained food-anticipatory activity rhythms in rats. Eur. J. Neurosci. 2009, 29:2217-2222.
239. Verwey M., Lam G.Y., Amir S. Circadian rhythms of PERIOD1 expression in the dorsomedial hypothalamic nucleus in the absence of entrained food-anticipatory activity rhythms in rats. Eur. J. Neurosci. 2009, 29:2217-2222.
240. Vrang N., Mrosovsky N., Mikkelsen J.D. Afferent projections to the hamster intergeniculate leaflet demonstrated by retrograde and anterograde tracing. Brain Res. Bull. 2003, 59:267-288.
241. Waddington Lamont E., Diaz L.R., Barry-Shaw J., Stewart J., Amir S. Daily restricted feeding rescues a rhythm of period2 expression in the arrhythmic suprachiasmatic nucleus. Neuroscience 2005, 132:245-248.
242. Wakamatsu H., Yoshinobu Y., Aida R., Moriya T., Akiyama M., Shibata S. Restricted-feeding-induced anticipatory activity rhythm is associated with a phase-shift of the expression of mPer1 and mPer2 mRNA in the cerebral cortex and hippocampus but not in the suprachiasmatic nucleus of mice. Eur. J. Neurosci. 2001, 13:1190-1196.
243. Watson S.J., Barchas J.D., Li C.H. Beta-lipotropin - localization of cells and axons in rat-brain by immunocytochemistry. Proc. Natl. Acad. Sci. U.S.A. 1977, 74:5155-5158.
244. Watts A.G., Swanson L.W. Efferent projections of the suprachiasmatic nucleus: II. Studies using retrograde transport of fluorescent dyes and simultaneous peptide immunohistochemistry in the rat. J. Comp. Neurol. 1987, 258:230-252.
245. Watts A.G., Swanson L.W., Sanchez-Watts G. Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat. J. Comp. Neurol. 1987, 258:204-229.
246. Webb I.C., Baltazar R.M., Lehman M.N., Coolen L.M. Bidirectional interactions between the circadian and reward systems: is restricted food access a unique zeitgeber?. Euro. J. Neurosci. 2009, 30:1739-1748.
247. Wijnen H., Young M.W. Interplay of circadian clocks and metabolic rhythms. Ann. Rev. Genet. 2006, 40:409-448.
248. Wu T., Ni Y., Dong Y., Xu J., Song X., Kato H., Fu Z. Regulation of circadian gene expression in the kidney by light and food cues in rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2010, 298:R635-R641.
249. Yan L., Foley N.C., Bobula J.M., Kriegsfeld L.J., Silver R. Two antiphase oscillations occur in each suprachiasmatic nucleus of behaviorally split hamsters. J. Neurosci. 2005, 25:9017-9026.
250. Yanagida H., Morita T., Kim J., Yoshida K., Nakajima K., Oomura Y., Wayner M.J., Sasaki K. Effects of ghrelin on neuronal activity in the ventromedial nucleus of the hypothalamus in infantile rats: an in vitro study. Peptides 2008, 29:912-918.
251. Yannielli P.C., Molyneux P.C., Harrington M.E., Golombek D.A. Ghrelin effects on the circadian system of mice. J. Neurosci. 2007, 27:2890-2895.
252. Yi C.X., van der Vliet J., Dai J., Yin G., Ru L., Buijs R.M. Ventromedial arcuate nucleus communicates peripheral metabolic information to the suprachiasmatic nucleus. Endocrinology 2006, 147:283-294.
253. Zhang D.X., Rusak B. Photic sensitivity of geniculate neurons that project to the suprachiasmatic nuclei or the contralateral geniculate. Brain Res. 1989, 504:161-164.
254. Zheng B., Larkin D., Albrecht U., Sun Z., Sage M., Eichele G., Lee C., Bradley A. The mPer2 gene encodes a functional component of the mammalian circadian clock. Nature 1999, 400:169-173.
255. Zheng H., Corkern M., Stoyanova I., Patterson L.M., Tian R., Berthoud H.R. Peptides that regulate food intake: appetite-inducing accumbens manipulation activates hypothalamic orexin neurons and inhibits POMC neurons. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2003, 284:R1436-R1444.
256. Zigman J.M., Jones J.E., Lee C.E., Saper C.B., Elmquist J.K. Expression of ghrelin receptor mRNA in the rat and the mouse brain. J. Comp. Neurol. 2006, 494:528-548.