메뉴 건너뛰기




Volumn 301, Issue 6, 2011, Pages

Pharmacological AMP-kinase activators have compartment-specific effects on cell physiology

Author keywords

Acetyl CoA carboxylase; Nucleolus; Transcription

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACETYL COENZYME A CARBOXYLASE; ADENYLATE KINASE; PHENFORMIN; RESVERATROL;

EID: 82455192875     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00309.2011     Document Type: Article
Times cited : (16)

References (54)
  • 3
    • 0037025356 scopus 로고    scopus 로고
    • AMP-activated Protein Kinase Suppresses Protein Synthesis in Rat Skeletal Muscle through Down-regulated Mammalian Target of Rapamycin (mTOR) Signaling
    • Bolster DR, Crozier SJ, Kimball SR, Jefferson LS. AMP-activated Protein Kinase Suppresses Protein Synthesis in Rat Skeletal Muscle through Down-regulated Mammalian Target of Rapamycin (mTOR) Signaling. J Biol Chem 277: 23977-23980, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 23977-23980
    • Bolster, D.R.1    Crozier, S.J.2    Kimball, S.R.3    Jefferson, L.S.4
  • 4
    • 1642328617 scopus 로고    scopus 로고
    • Stimulation of the AMP-activated Protein Kinase Leads to Activation of Eukaryotic Elongation Factor 2 Kinase and to Its Phosphorylation at a Novel Site, Serine 398
    • Browne GJ, Finn SG, Proud CG. Stimulation of the AMP-activated Protein Kinase Leads to Activation of Eukaryotic Elongation Factor 2 Kinase and to Its Phosphorylation at a Novel Site, Serine 398. J Biol Chem 279: 12220-12231, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 12220-12231
    • Browne, G.J.1    Finn, S.G.2    Proud, C.G.3
  • 5
    • 77957349477 scopus 로고    scopus 로고
    • AMP-activated protein kinase and its downstream transcriptional pathways
    • Canto C, Auwerx J. AMP-activated protein kinase and its downstream transcriptional pathways. Cell Mol Life Sci 67: 3407-3423, 2010.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 3407-3423
    • Canto, C.1    Auwerx, J.2
  • 6
    • 82455166771 scopus 로고    scopus 로고
    • Targeting therapeutic effects: Subcellular location matters. Focus on Pharmacological AMP-kinase activators have compartmentspecific effects on cell physiology
    • September 28, 10.1152/ajpcell.00358.2011
    • Creighton J. Targeting therapeutic effects: subcellular location matters. Focus on "Pharmacological AMP-kinase activators have compartmentspecific effects on cell physiology." Am J Physiol Cell Physiol (September 28, 2011). doi:10.1152/ajpcell.00358.2011.
    • (2011) Am J Physiol Cell Physiol
    • Creighton, J.1
  • 7
    • 33745183847 scopus 로고    scopus 로고
    • Functions of AMP-activated protein kinase in adipose tissue
    • Daval M, Foufelle F, Ferré P. Functions of AMP-activated protein kinase in adipose tissue. J Physiol 574: 55-62, 2006.
    • (2006) J Physiol , vol.574 , pp. 55-62
    • Daval, M.1    Foufelle, F.2    Ferré, P.3
  • 8
    • 44949122687 scopus 로고    scopus 로고
    • STRADa regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7
    • Dorfman J, Macara IG. STRADa regulates LKB1 localization by blocking access to importin-alpha, and by association with Crm1 and exportin-7. Mol Biol Cell 19: 1614-1626, 2008.
    • (2008) Mol Biol Cell , vol.19 , pp. 1614-1626
    • Dorfman, J.1    Macara, I.G.2
  • 9
    • 33745204925 scopus 로고    scopus 로고
    • AMPK alterations in cardiac physiology and pathology: Enemy or ally?
    • Dyck JRB, Lopaschuk GD. AMPK alterations in cardiac physiology and pathology: enemy or ally? J Physiol 574: 95-112, 2006.
    • (2006) J Physiol , vol.574 , pp. 95-112
    • Dyck, J.R.B.1    Lopaschuk, G.D.2
  • 10
    • 63849193776 scopus 로고    scopus 로고
    • AMPK-dependent hormonal regulation of whole-body energy metabolism
    • Dzamko NL, Steinberg GR. AMPK-dependent hormonal regulation of whole-body energy metabolism. Acta Physiol (Oxf) 196: 115-127, 2009.
    • (2009) Acta Physiol (Oxf) , vol.196 , pp. 115-127
    • Dzamko, N.L.1    Steinberg, G.R.2
  • 14
    • 50049091255 scopus 로고    scopus 로고
    • AMPK: A key regulator of energy balance in the single cell and the whole organism
    • Hardie DG. AMPK: a key regulator of energy balance in the single cell and the whole organism. Int J Obesity 32, Suppl 4: S7-S12, 2008.
    • (2008) Int J Obesity , vol.32 , Issue.SUPPL. 4
    • Hardie, D.G.1
  • 15
    • 33745225026 scopus 로고    scopus 로고
    • AMP-activated protein kinase - development of the energy sensor concept
    • Hardie DG, Hawley SA, Scott JW. AMP-activated protein kinase - development of the energy sensor concept. J Physiol 574: 7-15, 2006.
    • (2006) J Physiol , vol.574 , pp. 7-15
    • Hardie, D.G.1    Hawley, S.A.2    Scott, J.W.3
  • 18
    • 77949882555 scopus 로고    scopus 로고
    • Mechanisms linking obesity, chronic kidney disease, and fatty liver disease: The roles of fetuin-A, adiponectin, and AMPK
    • Ix JH, Sharma K. Mechanisms linking obesity, chronic kidney disease, and fatty liver disease: the roles of fetuin-A, adiponectin, and AMPK. J Am Soc Nephrol 21: 406-412, 2010.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 406-412
    • Ix, J.H.1    Sharma, K.2
  • 19
    • 77956772446 scopus 로고    scopus 로고
    • Sensing the fuels: Glucose and lipid signaling in the CNS controlling energy homeostasis
    • Jordan SD, Konner AC, Bruning JC. Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis. Cell Mol Life Sci 67: 3255-3273, 2010.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 3255-3273
    • Jordan, S.D.1    Konner, A.C.2    Bruning, J.C.3
  • 20
    • 77958066938 scopus 로고    scopus 로고
    • Identification of a nuclear export signal in the catalytic subunit of AMP-activated protein kinase
    • Kazgan N, Williams T, Forsberg LJ, Brenman JE. Identification of a nuclear export signal in the catalytic subunit of AMP-activated protein kinase. Mol Biol Cell 21: 3433-3442, 2010.
    • (2010) Mol Biol Cell , vol.21 , pp. 3433-3442
    • Kazgan, N.1    Williams, T.2    Forsberg, L.J.3    Brenman, J.E.4
  • 21
    • 63849162173 scopus 로고    scopus 로고
    • AMP-activated protein kinase: A core signalling pathway in the heart
    • Kim AS, Miller EJ, Young LH. AMP-activated protein kinase: a core signalling pathway in the heart. Acta Physiol (Oxf) 196: 37-53, 2009.
    • (2009) Acta Physiol (Oxf) , vol.196 , pp. 37-53
    • Kim, A.S.1    Miller, E.J.2    Young, L.H.3
  • 22
    • 79551601710 scopus 로고    scopus 로고
    • Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway
    • Kitada M, Kume S, Imaizumi N, Koya D. Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway. Diabetes 60: 634-643, 2011.
    • (2011) Diabetes , vol.60 , pp. 634-643
    • Kitada, M.1    Kume, S.2    Imaizumi, N.3    Koya, D.4
  • 23
    • 79957870187 scopus 로고    scopus 로고
    • Computer-based fluorescence quantification: A novel approach to study nucleolar biology
    • Kodiha M, Banski P, Stochaj U. Computer-based fluorescence quantification: a novel approach to study nucleolar biology. BMC Cell Biol 12: 25, 2011.
    • (2011) BMC Cell Biol , vol.12 , pp. 25
    • Kodiha, M.1    Banski, P.2    Stochaj, U.3
  • 24
    • 55649105063 scopus 로고    scopus 로고
    • Analysis of signaling events by combining high-throughput screening technology with computer-based image analysis
    • Kodiha M, Brown CM, Stochaj U. Analysis of signaling events by combining high-throughput screening technology with computer-based image analysis. Sci Signal 1: pl2, 2008.
    • (2008) Sci Signal , vol.1 , Issue.pl2
    • Kodiha, M.1    Brown, C.M.2    Stochaj, U.3
  • 26
    • 80755148806 scopus 로고    scopus 로고
    • AMP kinase -the missing link between type 2 diabetes and neurodegenerative diseases?
    • In press
    • Kodiha M, Stochaj U. AMP kinase -the missing link between type 2 diabetes and neurodegenerative diseases? Trends Mol Med. In press.
    • Trends Mol Med
    • Kodiha, M.1    Stochaj, U.2
  • 27
    • 84856515044 scopus 로고    scopus 로고
    • Targeting AMPK For Therapeutic Intervention In Type 2 Diabetes. In: Medical Complications of Type 2 Diabetes
    • edited by Croniger C. ISBN: 978-953-307-363-7. Rijeka, Croatia: InTech, Available from
    • Kodiha M, Stochaj U. Targeting AMPK for therapeutic intervention in type 2 diabetes. In: Medical Complications of Type 2 Diabetes, edited by Croniger C. ISBN: 978-953-307-363-7. Rijeka, Croatia: InTech, 2011. [Available from http://www.intechopen.com/articles/show/title/targetingampk-for-therapeutic-intervention-in-type-2-diabetes].
    • (2011)
    • Kodiha, M.1    Stochaj, U.2
  • 28
    • 77949523576 scopus 로고    scopus 로고
    • Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors
    • Kodiha M, Tran D, Morogan A, Qian C, Stochaj U. Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors. PLos One 4: e8420, 2009.
    • (2009) PLos One , vol.e8420 , pp. 4
    • Kodiha, M.1    Tran, D.2    Morogan, A.3    Qian, C.4    Stochaj, U.5
  • 30
    • 77649271004 scopus 로고    scopus 로고
    • Effects of AMP-activated protein kinase in cerebral ischemia
    • Li J, McCullough LD. Effects of AMP-activated protein kinase in cerebral ischemia. J Cereb Blood Flow Metab 30: 480-492, 2010.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 480-492
    • Li, J.1    McCullough, L.D.2
  • 31
    • 70349627818 scopus 로고    scopus 로고
    • UCF-101 mitigates streptozotocin-induced cardiomyocyte dysfunction: Role of AMPK
    • Li Q, Li J, Ren J. UCF-101 mitigates streptozotocin-induced cardiomyocyte dysfunction: role of AMPK. Am J Physiol Endocrinol Metab 297: E965-E973, 2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Li, Q.1    Li, J.2    Ren, J.3
  • 32
    • 33745815985 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling in metabolic regulation
    • Long YC, Zierath JR. AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest 116: 1776-1783, 2006.
    • (2006) J Clin Invest , vol.116 , pp. 1776-1783
    • Long, Y.C.1    Zierath, J.R.2
  • 33
    • 50049086740 scopus 로고    scopus 로고
    • AMP-activated protein kinase control of energy metabolism in the ischemic heart
    • Lopaschuk GD. AMP-activated protein kinase control of energy metabolism in the ischemic heart. Int J Obes 32: S29-S35, 2008.
    • (2008) Int J Obes , vol.32
    • Lopaschuk, G.D.1
  • 36
    • 74349090643 scopus 로고    scopus 로고
    • The role of AMP-activated protein kinase in the cardiovascular system
    • Nagata D, Hirata Y. The role of AMP-activated protein kinase in the cardiovascular system. Hypertens Res 33: 22-28, 2010.
    • (2010) Hypertens Res , vol.33 , pp. 22-28
    • Nagata, D.1    Hirata, Y.2
  • 38
    • 34250165409 scopus 로고    scopus 로고
    • The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress
    • Quan X, Yu J, Bussey H, Stochaj U. The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress. Biochim Biophys Acta 1773: 1052-1061, 2007.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1052-1061
    • Quan, X.1    Yu, J.2    Bussey, H.3    Stochaj, U.4
  • 42
    • 34147152841 scopus 로고    scopus 로고
    • Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade
    • Sanders MJ, Grondin PO, Hegarty BD, Snowden MA, Carling D. Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade. Biochem J 403: 139-148, 2007.
    • (2007) Biochem J , vol.403 , pp. 139-148
    • Sanders, M.J.1    Grondin, P.O.2    Hegarty, B.D.3    Snowden, M.A.4    Carling, D.5
  • 43
    • 67749111502 scopus 로고    scopus 로고
    • The LKB1-AMPK pathway: Metabolism and growth control in tumour suppression
    • Shackelford DB, Shaw RJ. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer 9: 563-575, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 563-575
    • Shackelford, D.B.1    Shaw, R.J.2
  • 44
    • 67650914230 scopus 로고    scopus 로고
    • AMPK in Health and Disease
    • Steinberg GR, Kemp BE. AMPK in Health and Disease. Physiol Rev 89: 1025-1078, 2009.
    • (2009) Physiol Rev , vol.89 , pp. 1025-1078
    • Steinberg, G.R.1    Kemp, B.E.2
  • 45
    • 4844224721 scopus 로고    scopus 로고
    • Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor B
    • Storz P, Doppler H, Toker A. Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor B. Mol Pharmacol 66: 870-879, 2004.
    • (2004) Mol Pharmacol , vol.66 , pp. 870-879
    • Storz, P.1    Doppler, H.2    Toker, A.3
  • 46
    • 34250182374 scopus 로고    scopus 로고
    • Leptin stimulates fatty acid oxidation and peroxisome proliferator-activated receptor alpha gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the α2 form of AMP-activated protein kinase
    • Suzuki A, Okamoto S, Lee S, Saito K, Shiuchi T, Minokoshi Y. Leptin stimulates fatty acid oxidation and peroxisome proliferator-activated receptor alpha gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the α2 form of AMP-activated protein kinase. Mol Cell Biol 27: 4317-4327, 2007.
    • (2007) Mol Cell Biol , vol.27 , pp. 4317-4327
    • Suzuki, A.1    Okamoto, S.2    Lee, S.3    Saito, K.4    Shiuchi, T.5    Minokoshi, Y.6
  • 47
    • 78851469053 scopus 로고    scopus 로고
    • Anti-diabetic effects of resveratrol
    • Szkudelski T, Szkudelska K. Anti-diabetic effects of resveratrol. Ann NY Acad Sci 1215: 34-39, 2011.
    • (2011) Ann NY Acad Sci , vol.1215 , pp. 34-39
    • Szkudelski, T.1    Szkudelska, K.2
  • 49
    • 78049438321 scopus 로고    scopus 로고
    • AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction
    • Turdi S, Fan X, Li J, Zhao J, Huff AF, Du M, Ren J. AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction. Aging Cell 9: 592-606, 2010.
    • (2010) Aging Cell , vol.9 , pp. 592-606
    • Turdi, S.1    Fan, X.2    Li, J.3    Zhao, J.4    Huff, A.F.5    Du, M.6    Ren, J.7
  • 52
    • 78049253547 scopus 로고    scopus 로고
    • PP2A mediated AMPK inhibition promotes HSP70 expression in heat shock response
    • Wang T, Yu Q, Chen J, Deng B, Qian L, Le Y. PP2A mediated AMPK inhibition promotes HSP70 expression in heat shock response. PLos One 5: e13096, 2010.
    • (2010) PLos One , vol.e13096 , pp. 5
    • Wang, T.1    Yu, Q.2    Chen, J.3    Deng, B.4    Qian, L.5    Le, Y.6
  • 53
    • 57349094302 scopus 로고    scopus 로고
    • AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism
    • Witczak C, Sharoff C, Goodyear L. AMP-activated protein kinase in skeletal muscle: from structure and localization to its role as a master regulator of cellular metabolism. Cell Mol Life Sci 65: 3737-3755, 2008.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3737-3755
    • Witczak, C.1    Sharoff, C.2    Goodyear, L.3
  • 54
    • 65349177200 scopus 로고    scopus 로고
    • AMPK: An emerging drug target for diabetes and the metabolic syndrome
    • Zhang BB, Zhou G, Li C. AMPK: an emerging drug target for diabetes and the metabolic syndrome. Cell Metab 9: 407-416, 2009.
    • (2009) Cell Metab , vol.9 , pp. 407-416
    • Zhang, B.B.1    Zhou, G.2    Li, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.