Silver nanoparticles induce apoptosis and G2/M arrest via PKCζ-dependent signaling in A549 lung cells

Archives of Toxicology

Volumn 85, Issue 12, 2011, Pages 1529-1540

  Lee, Young Sook ^a   Kim, Dong Woon ^a   Lee, Young Ho ^a   Oh, Jung Hwa ^b   Yoon, Seokjoo ^b   Choi, Mi Sun ^b   Lee, Sung Kyu ^b   Kim, Ji Won ^b   Lee, Kyuhong ^c   Song, Chang Woo ^c  

^a Chungnam National University   (South Korea)

^b Korea Institute of Toxicology   (South Korea)

^c Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Apoptosis; G2 M arrest; Protein kinase C (PKC) ; Silver nanoparticles (Ag NPs)

Indexed keywords

FORMAZAN; LACTATE DEHYDROGENASE; MESSENGER RNA; PROTEIN KINASE C ZETA; SILVER NANOPARTICLE;

APOPTOSIS; ARTICLE; BAX GENE; BID GENE; BIOACCUMULATION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY TEST; DOWN REGULATION; ENZYME ASSAY; ENZYME RELEASE; FLOW CYTOMETRY; GENE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; PROTO ONCOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

APOPTOSIS; CELL DIVISION; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; G2 PHASE; HUMANS; LUNG; NANOPARTICLES; PROTEIN KINASE C; RNA, MESSENGER; SIGNAL TRANSDUCTION; SILVER;

EID: 82355168780     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0714-1     Document Type: Article

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