-
1
-
-
0035524488
-
Toll-like receptors and innate immunity
-
Medzhitov, R. (2001) Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1, 135-145.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 135-145
-
-
Medzhitov, R.1
-
2
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira, S., Uematsu, S. and Takeuchi, O. (2006) Pathogen recognition and innate immunity. Cell 124, 783-804.
-
(2006)
Cell
, vol.124
, pp. 783-804
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
3
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth, S.C., Colegio, O.R., O'Connor, W. Jr., Sutterwale, F.S. and Flavell, R.A. (2008) Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453, 1122-1126.
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor Jr., W.3
Sutterwale, F.S.4
Flavell, R.A.5
-
4
-
-
27844541797
-
Control of Bcell responses by Toll-like receptors
-
Pasare, C. and Medzhitov, R. (2005) Control of Bcell responses by Toll-like receptors. Nature 438, 364-368.
-
(2005)
Nature
, vol.438
, pp. 364-368
-
-
Pasare, C.1
Medzhitov, R.2
-
6
-
-
0036217975
-
Origins and functions of B-1 cells with notes on the role of CD5
-
Berland, R. and Wortis, H.H. (2002) Origins and functions of B-1 cells with notes on the role of CD5. Annu. Rev. Immunol. 20, 253-300.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 253-300
-
-
Berland, R.1
Wortis, H.H.2
-
7
-
-
38949216060
-
LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1
-
Rastelli, J., Hömig-Hölzel, C., Seagal, J., Müller, W., Hermann, A.C., Rajewsky, K. and Zimber-Strobl, U. (2008) LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1. Blood 111, 1448-1455.
-
(2008)
Blood
, vol.111
, pp. 1448-1455
-
-
Rastelli, J.1
Hömig-Hölzel, C.2
Seagal, J.3
Müller, W.4
Hermann, A.C.5
Rajewsky, K.6
Zimber-Strobl, U.7
-
8
-
-
0008411148
-
Organization of immunoglobulin heavy chain genes and allelic deletion model
-
Honjo, T. and Kataoka, T. (1978) Organization of immunoglobulin heavy chain genes and allelic deletion model. Proc. Natl. Acad. Sci. U.S.A. 75, 2140-2144.
-
(1978)
Proc. Natl. Acad. Sci. U. S. A.
, vol.75
, pp. 2140-2144
-
-
Honjo, T.1
Kataoka, T.2
-
9
-
-
42649123314
-
Mechanism and regulation of class switch recombination
-
Stavnezer, J., Guikema, J.E. and Schrader, C.E. (2008) Mechanism and regulation of class switch recombination. Annu. Rev. Immunol. 26, 261-292.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 261-292
-
-
Stavnezer, J.1
Guikema, J.E.2
Schrader, C.E.3
-
10
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu, M., Kinoshita, K., Fagarasan, S., Yamada, S., Shinkai, Y. and Honjo, T. (2000) Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102, 553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
11
-
-
0034264851
-
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
-
Revy, P., Muto, T., Levy, Y., Geissman, F., Piebani, A., Sanal, O., Catalan, N., Forveille, M., Dufourcq-Labelouse, R., Gennery, A., Tezcan, I., Ersoy, F., Kayserill, H., Uqazio, A.G., Brousse, N., Muramatsu, M., Notaranqelo, L.D., Kinoshita, K., Honjo, T., Fisher, A. and Durandy, A. (2000) Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell 102, 565-575.
-
(2000)
Cell
, vol.102
, pp. 565-575
-
-
Revy, P.1
Muto, T.2
Levy, Y.3
Geissman, F.4
Piebani, A.5
Sanal, O.6
Catalan, N.7
Forveille, M.8
Dufourcq-Labelouse, R.9
Gennery, A.10
Tezcan, I.11
Ersoy, F.12
Kayserill, H.13
Uqazio, A.G.14
Brousse, N.15
Muramatsu, M.16
Notaranqelo, L.D.17
Kinoshita, K.18
Honjo, T.19
Fisher, A.20
Durandy, A.21
more..
-
12
-
-
14944362858
-
Regulation of plasma-cell development
-
Shapiro-Shelef, M. and Calame, K. (2005) Regulation of plasma-cell development. Nat. Rev. Immunol. 5, 230-242.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 230-242
-
-
Shapiro-Shelef, M.1
Calame, K.2
-
13
-
-
15444346834
-
Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function
-
Mittrucker, H.W., Matsuyama, T., Grossman, A., Kundig, T.M., Potter, J., Shahinian, A., Wakeham, A., Patterson, B., Ohashi, P.S. and Mak, T.W. (1997) Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 275, 540-543.
-
(1997)
Science
, vol.275
, pp. 540-543
-
-
Mittrucker, H.W.1
Matsuyama, T.2
Grossman, A.3
Kundig, T.M.4
Potter, J.5
Shahinian, A.6
Wakeham, A.7
Patterson, B.8
Ohashi, P.S.9
Mak, T.W.10
-
14
-
-
0035804276
-
Allergy and allergic diseases. First of two parts
-
Kay, A.B. (2001) Allergy and allergic diseases. First of two parts. N. Engl. J. Med. 344, 30-37.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 30-37
-
-
Kay, A.B.1
-
15
-
-
47949107183
-
The development of allergic inflammation
-
Galli, S.J., Tsai, M. and Piliponsky, A.M. (2008) The development of allergic inflammation. Nature 454, 445-454.
-
(2008)
Nature
, vol.454
, pp. 445-454
-
-
Galli, S.J.1
Tsai, M.2
Piliponsky, A.M.3
-
16
-
-
33947210941
-
Role of cytokines in allergic inflammation
-
Nakajima, H. and Takatsu, K. (2007) Role of cytokines in allergic inflammation. Int. Arch. Allergy Immunol. 142, 265-273.
-
(2007)
Int. Arch. Allergy Immunol.
, vol.142
, pp. 265-273
-
-
Nakajima, H.1
Takatsu, K.2
-
17
-
-
0002670543
-
Is there evidence for a nonantigen specific diffusable chemical mediator from the thymus-derived cell in the initiation of the immune response?
-
Dutton, R.W., Falkoff, R., Hirst, J.A., Hoffman, M., Kappler, J.W., Kettman, J.R., Lesley, J.F. and Van, D. (1971) Is there evidence for a nonantigen specific diffusable chemical mediator from the thymus-derived cell in the initiation of the immune response? Prog. Immunl. 1, 355-368.
-
(1971)
Prog. Immunl.
, vol.1
, pp. 355-368
-
-
Dutton, R.W.1
Falkoff, R.2
Hirst, J.A.3
Hoffman, M.4
Kappler, J.W.5
Kettman, J.R.6
Lesley, J.F.7
Van, D.8
-
18
-
-
0015492733
-
Replacement of T-cell function by a T-cell product
-
Schimpl, A. and Wecker, E. (1972) Replacement of T-cell function by a T-cell product. Nature (New Biol.) 237, 15-17.
-
(1972)
Nature (New Biol.)
, vol.237
, pp. 15-17
-
-
Schimpl, A.1
Wecker, E.2
-
19
-
-
0024155507
-
Molecular regulation of B lymphocyte response
-
Kishimoto, T. and Hirano, T. (1988) Molecular regulation of B lymphocyte response. Annu. Rev. Immunol. 6, 485-512.
-
(1988)
Annu. Rev. Immunol.
, vol.6
, pp. 485-512
-
-
Kishimoto, T.1
Hirano, T.2
-
20
-
-
0023069479
-
B-cell stimulatory factor-1/Interleukin 4
-
Paul, W.E. and Ohara, J. (1987) B-cell stimulatory factor-1/Interleukin 4. Annu. Rev. Immunol. 5, 429-459.
-
(1987)
Annu. Rev. Immunol.
, vol.5
, pp. 429-459
-
-
Paul, W.E.1
Ohara, J.2
-
21
-
-
0015959322
-
Enhancing factor on anti-hapten antibody response released from PPDs-stimulated Tubercle bacilli-sensitized cells
-
Takatsu, K., Haba, S., Aoki, T. and Kitagawa, M. (1974) Enhancing factor on anti-hapten antibody response released from PPDs-stimulated Tubercle bacilli-sensitized cells. Immunochemistry 11, 107-109.
-
(1974)
Immunochemistry
, vol.11
, pp. 107-109
-
-
Takatsu, K.1
Haba, S.2
Aoki, T.3
Kitagawa, M.4
-
22
-
-
0018837746
-
Antigen-induced T cell-replacing factor (TRF). I. Functional characterization of a TRF-producing helper T cell subset and genetic studies on TRF production
-
Takatsu, K., Tominaga, A. and Hamaoka, T. (1980) Antigen-induced T cell-replacing factor (TRF). I. Functional characterization of a TRF-producing helper T cell subset and genetic studies on TRF production. J. Immunol. 124, 2414-2422.
-
(1980)
J. Immunol.
, vol.124
, pp. 2414-2422
-
-
Takatsu, K.1
Tominaga, A.2
Hamaoka, T.3
-
23
-
-
0023372379
-
Production of a monoclonal antibody useful in the molecular characterization of murine T-cell-replacing factor/B-cell growth factor II
-
Harada, N., Takahashi, T., Matsumoto, M., Kinashi, T., Kikuchi, Y., Koyama, N., Severinson, E., Yaoita, Y., Honjo, T., Yamaguchi, N., Tominaga, A. and Takatsu, K. (1987) Production of a monoclonal antibody useful in the molecular characterization of murine T-cell-replacing factor/B-cell growth factor II. Proc. Natl. Acad. Sci. U.S.A. 84, 4581-4585.
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 4581-4585
-
-
Harada, N.1
Takahashi, T.2
Matsumoto, M.3
Kinashi, T.4
Kikuchi, Y.5
Koyama, N.6
Severinson, E.7
Yaoita, Y.8
Honjo, T.9
Yamaguchi, N.10
Tominaga, A.11
Takatsu, K.12
-
24
-
-
0022469451
-
Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II
-
Kinashi, T., Harada, N., Severinson, E., Tanabe, T., Sideras, P., Konishi, M., Azuma, C., Tominaga, A., Bergstedt-Lindqvist, S., Takahashi, M., Matsuda, F., Yaoita, Y., Takatsu, K. and Honjo, T. (1986) Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II. Nature 324, 70-73.
-
(1986)
Nature
, vol.324
, pp. 70-73
-
-
Kinashi, T.1
Harada, N.2
Severinson, E.3
Tanabe, T.4
Sideras, P.5
Konishi, M.6
Azuma, C.7
Tominaga, A.8
Bergstedt-Lindqvist, S.9
Takahashi, M.10
Matsuda, F.11
Yaoita, Y.12
Takatsu, K.13
Honjo, T.14
-
25
-
-
0023818705
-
T cell-replacing factor (TRF)/interleukin 5 (IL-5): molecular and functional properties
-
Takatsu, K., Tominaga, A., Harada, N., Mita, S., Matsumoto, M., Takahashi, T., Kikuchi, Y. and Yamaguchi, N. (1988) T cell-replacing factor (TRF)/interleukin 5 (IL-5): molecular and functional properties. Immunol. Rev. 102, 107-135.
-
(1988)
Immunol. Rev.
, vol.102
, pp. 107-135
-
-
Takatsu, K.1
Tominaga, A.2
Harada, N.3
Mita, S.4
Matsumoto, M.5
Takahashi, T.6
Kikuchi, Y.7
Yamaguchi, N.8
-
26
-
-
0026643596
-
Interleukin-5, eosinophils, and disease
-
Sanderson, C.J. (1992) Interleukin-5, eosinophils, and disease. Blood 79, 3101-3109.
-
(1992)
Blood
, vol.79
, pp. 3101-3109
-
-
Sanderson, C.J.1
-
29
-
-
0020081969
-
Identification of a T cell-derived B cell growth factor distinct from interleukin 2
-
Howard, M., Farrar, J., Hilfiker, M., Johnson, B., Takatsu, K., Hamaoka, T. and Paul, W.E. (1982) Identification of a T cell-derived B cell growth factor distinct from interleukin 2. J. Exp. Med. 155, 914-923.
-
(1982)
J. Exp. Med.
, vol.155
, pp. 914-923
-
-
Howard, M.1
Farrar, J.2
Hilfiker, M.3
Johnson, B.4
Takatsu, K.5
Hamaoka, T.6
Paul, W.E.7
-
30
-
-
0020557435
-
Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays
-
Swain, S.L., Howard, M., Kappler, J., Marrack, P., Watson, J., Booth, R., Wetzel, G.D. and Dutton, R.W. (1983) Evidence for two distinct classes of murine B cell growth factors with activities in different functional assays. J. Exp. Med. 158, 822-835.
-
(1983)
J. Exp. Med.
, vol.158
, pp. 822-835
-
-
Swain, S.L.1
Howard, M.2
Kappler, J.3
Marrack, P.4
Watson, J.5
Booth, R.6
Wetzel, G.D.7
Dutton, R.W.8
-
31
-
-
0021244210
-
Establishment of three PPD-reactive helper T cell clones with distinct functions in B cell activation
-
Sano, Y., Yamada, G., Dobashi, K., Mizuochi, T., Hamaoka, T. and Takatsu, K. (1984) Establishment of three PPD-reactive helper T cell clones with distinct functions in B cell activation. J. Immunol. 133, 629-635.
-
(1984)
J. Immunol.
, vol.133
, pp. 629-635
-
-
Sano, Y.1
Yamada, G.2
Dobashi, K.3
Mizuochi, T.4
Hamaoka, T.5
Takatsu, K.6
-
32
-
-
0018871662
-
Antigen-induced T cell-replacing factor (TRF) II. X-linked gene control for the expression of TRFacceptor site(s) on B lymphocytes and preparation of specific antiserum to that acceptor
-
Tominaga, A., Takatsu, K. and Hamaoka, T. (1980) Antigen-induced T cell-replacing factor (TRF) II. X-linked gene control for the expression of TRFacceptor site(s) on B lymphocytes and preparation of specific antiserum to that acceptor. J. Immunol. 124, 2423-2429.
-
(1980)
J. Immunol.
, vol.124
, pp. 2423-2429
-
-
Tominaga, A.1
Takatsu, K.2
Hamaoka, T.3
-
33
-
-
0019417299
-
Antibody against T cellreplacing factor acceptor site(s) augments in vivo primary IgM responses to suboptimal doses of heterologous erythrocytes
-
Takatsu, K., Sano, Y., Tomita, S., Hashimoto, N. and Hamaoka, T. (1981) Antibody against T cellreplacing factor acceptor site(s) augments in vivo primary IgM responses to suboptimal doses of heterologous erythrocytes. Nature 292, 360-362.
-
(1981)
Nature
, vol.292
, pp. 360-362
-
-
Takatsu, K.1
Sano, Y.2
Tomita, S.3
Hashimoto, N.4
Hamaoka, T.5
-
34
-
-
0020020011
-
DBA/2Ha mice as a model of an X-linked immunodeficiency which is defective in the expression of TRFacceptor site(s) on B lymphocytes
-
Takatsu, K. and Hamaoka, T. (1982) DBA/2Ha mice as a model of an X-linked immunodeficiency which is defective in the expression of TRFacceptor site(s) on B lymphocytes. Immunol. Rev. 64, 239-268.
-
(1982)
Immunol. Rev.
, vol.64
, pp. 239-268
-
-
Takatsu, K.1
Hamaoka, T.2
-
35
-
-
0019192873
-
Antigen-induced T cell-replacing factor (TRF). III. Establishment of T cell hybridoma producing TRF and analysis of released TRF
-
Takatsu, K., Tanaka, K., Tominaga, A., Kumahara, Y. and Hamaoka, T. (1980) Antigen-induced T cell-replacing factor (TRF). III. Establishment of T cell hybridoma producing TRF and analysis of released TRF. J. Immunol. 125, 2646-2653.
-
(1980)
J. Immunol.
, vol.125
, pp. 2646-2653
-
-
Takatsu, K.1
Tanaka, K.2
Tominaga, A.3
Kumahara, Y.4
Hamaoka, T.5
-
36
-
-
0021813331
-
BCGFII activity on activated B cells of a purified murine T cellreplacing factor (TRF) from a T cell hybridoma (B151K12)
-
Harada, N., Kikuchi, Y., Tominaga, A., Takaki, S. and Takatsu, K. (1985) BCGFII activity on activated B cells of a purified murine T cellreplacing factor (TRF) from a T cell hybridoma (B151K12). J. Immunol. 134, 3944-3951.
-
(1985)
J. Immunol.
, vol.134
, pp. 3944-3951
-
-
Harada, N.1
Kikuchi, Y.2
Tominaga, A.3
Takaki, S.4
Takatsu, K.5
-
37
-
-
0022005386
-
Purification and physicochemical characterization of murine T cell-replacing factor (TRF)
-
Takatsu, K., Harada, N., Hara, Y., Takahama, Y., Yamada, G., Dobashi, K. and Hamaoka, T. (1985) Purification and physicochemical characterization of murine T cell-replacing factor (TRF). J. Immunol. 134, 382-389.
-
(1985)
J. Immunol.
, vol.134
, pp. 382-389
-
-
Takatsu, K.1
Harada, N.2
Hara, Y.3
Takahama, Y.4
Yamada, G.5
Dobashi, K.6
Hamaoka, T.7
-
38
-
-
0023893708
-
Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors
-
Yamaguchi, Y., Hayashi, Y., Sugama, Y., Miura, Y., Kasahara, T., Torisu, T., Mita, S., Tominaga, A., Takatsu, K. and Suda, T. (1988) Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J. Exp. Med. 167, 1737-1742.
-
(1988)
J. Exp. Med.
, vol.167
, pp. 1737-1742
-
-
Yamaguchi, Y.1
Hayashi, Y.2
Sugama, Y.3
Miura, Y.4
Kasahara, T.5
Torisu, T.6
Mita, S.7
Tominaga, A.8
Takatsu, K.9
Suda, T.10
-
39
-
-
0023875104
-
Purified interleukin-5 supports the terminal differentiation and proliferation of murine eosinophilic precursors
-
Yamaguchi, Y., Suda, T., Suda, J., Eguchi, M., Miura, Y., Harada, N., Tominaga, A. and Takatsu, K. (1988) Purified interleukin-5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J. Exp. Med. 167, 43-56.
-
(1988)
J. Exp. Med.
, vol.167
, pp. 43-56
-
-
Yamaguchi, Y.1
Suda, T.2
Suda, J.3
Eguchi, M.4
Miura, Y.5
Harada, N.6
Tominaga, A.7
Takatsu, K.8
-
40
-
-
0344019003
-
Interleukin 5, a T-cellderived B-cell differentiation factor also induces cytotoxic T lymphocytes
-
Takatsu, K., Kikuchi, Y., Takahashi, T., Honjo, T., Matsumoto, M., Harada, N., Yamaguchi, N. and Tominaga, A. (1987) Interleukin 5, a T-cellderived B-cell differentiation factor also induces cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 84, 4234-4238.
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 4234-4238
-
-
Takatsu, K.1
Kikuchi, Y.2
Takahashi, T.3
Honjo, T.4
Matsumoto, M.5
Harada, N.6
Yamaguchi, N.7
Tominaga, A.8
-
41
-
-
0028673423
-
Interleukin-5 and its receptor system in the immune system and inflammation
-
Takatsu, K., Takaki, S. and Hitoshi, Y. (1994) Interleukin-5 and its receptor system in the immune system and inflammation. Adv. Immunol. 57, 145-190.
-
(1994)
Adv. Immunol.
, vol.57
, pp. 145-190
-
-
Takatsu, K.1
Takaki, S.2
Hitoshi, Y.3
-
42
-
-
82355161358
-
Interleukin-5
-
(eds. Sporn, M.B. and Roberts, A.B.). Springer-Verlag, New York
-
Honjo, T. and Takatsu, K. (1990) Interleukin-5. In Peptide Growth Factors and Their Receptor I (eds. Sporn, M.B. and Roberts, A.B.). Springer-Verlag, New York, pp. 609-632.
-
(1990)
Peptide Growth Factors and Their Receptor I
, pp. 609-632
-
-
Honjo, T.1
Takatsu, K.2
-
43
-
-
0023057192
-
Cloning of cDNA encoding human T-cell replacing factor (Interleukin-5) and comparison with the murine homologue
-
Azuma, C., Tanabe, T., Konishi, M., Kinashi, T., Noma, T., Matsuda, R., Yaoita, Y., Takatsu, K., Hammarstrom, L., Smith, L.I.E., Severinson, E. and Honjo, T. (1986) Cloning of cDNA encoding human T-cell replacing factor (Interleukin-5) and comparison with the murine homologue. Nucleic Acids Res. 14, 9149-9158.
-
(1986)
Nucleic Acids Res
, vol.14
, pp. 9149-9158
-
-
Azuma, C.1
Tanabe, T.2
Konishi, M.3
Kinashi, T.4
Noma, T.5
Matsuda, R.6
Yaoita, Y.7
Takatsu, K.8
Hammarstrom, L.9
Smith, L.I.E.10
Severinson, E.11
Honjo, T.12
-
44
-
-
0023433306
-
Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin-5)
-
Campbell, H.D., Tucker, W.Q.J., Hort, Y., Martinson, M.E., Mayo, G., Clutterbuck, E.J., Sanderson, C.J. and Young, I. (1987) Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin-5). Proc. Natl. Acad. Sci. U.S.A. 84, 6629-6633.
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 6629-6633
-
-
Campbell, H.D.1
Tucker, W.Q.J.2
Hort, Y.3
Martinson, M.E.4
Mayo, G.5
Clutterbuck, E.J.6
Sanderson, C.J.7
Young, I.8
-
45
-
-
0029153441
-
Definition of cis-regulatory elements of the interleukin-5 gene promoter, Involvement of nuclear factor of activated T cellrelated factors in interleukin-5 expression
-
Lee, H.J., Masuda, E.S., Arai, N., Arai, K. and Yokota, T. (1995) Definition of cis-regulatory elements of the interleukin-5 gene promoter. Involvement of nuclear factor of activated T cellrelated factors in interleukin-5 expression. J. Biol. Chem. 270, 17541-17550.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17541-17550
-
-
Lee, H.J.1
Masuda, E.S.2
Arai, N.3
Arai, K.4
Yokota, T.5
-
46
-
-
0024563995
-
IL-4 and IL-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemia with a del(5q)
-
Le Beau, M.M., Lemons, E.R.S., Espinosa, R. III, Larson, R.A., Arai, N. and Rowley, J.D. (1988) IL-4 and IL-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemia with a del(5q). Blood 73, 647-650.
-
(1988)
Blood
, vol.73
, pp. 647-650
-
-
Le Beau, M.M.1
Lemons, E.R.S.2
Espinosa III, R.3
Larson, R.A.4
Arai, N.5
Rowley, J.D.6
-
47
-
-
0032531605
-
Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3
-
Zhang, D.-H., Yang, L. and Ray, A. (1998) Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3. J. Immunol. 161, 3817-3821.
-
(1998)
J. Immunol.
, vol.161
, pp. 3817-3821
-
-
Zhang, D.-H.1
Yang, L.2
Ray, A.3
-
48
-
-
3042598052
-
Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci
-
Yamashita, M., Ukai-Tadenuma, M., Miyamoto, T., Sugaya, K., Hosokawa, H., Hasegawa, A., Kimura, M., Taniguchi, M., DeGregali, J. and Nakayama, T. (2004) Essential role of GATA3 for the maintenance of type 2 helper T (Th2) cytokine production and chromatin remodeling at the Th2 cytokine gene loci. J. Biol. Chem. 279, 26983-26990.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 26983-26990
-
-
Yamashita, M.1
Ukai-Tadenuma, M.2
Miyamoto, T.3
Sugaya, K.4
Hosokawa, H.5
Hasegawa, A.6
Kimura, M.7
Taniguchi, M.8
DeGregali, J.9
Nakayama, T.10
-
49
-
-
0023874179
-
Molecular properties and regulation of mRNA expression for murine T cell-replacing factor/IL-5
-
Tominaga, A., Matsumoto, M., Harada, N., Takahashi, T., Kikuchi, Y. and Takatsu, K. (1988) Molecular properties and regulation of mRNA expression for murine T cell-replacing factor/IL-5. J. Immunol. 140, 1175-1181.
-
(1988)
J. Immunol.
, vol.140
, pp. 1175-1181
-
-
Tominaga, A.1
Matsumoto, M.2
Harada, N.3
Takahashi, T.4
Kikuchi, Y.5
Takatsu, K.6
-
50
-
-
0025055641
-
Role of carbohydrate moiety of IL-5. Effect of tunicamycin on the glycosylation of IL-5 and the biologic activity of deglycosylated IL-5
-
Tominaga, A., Takahashi, T., Kikuchi, Y., Mita, S., Naomi, S., Harada, N., Yamaguchi, N. and Takatsu, K. (1990) Role of carbohydrate moiety of IL-5. Effect of tunicamycin on the glycosylation of IL-5 and the biologic activity of deglycosylated IL-5. J. Immunol. 144, 1345-1352.
-
(1990)
J. Immunol.
, vol.144
, pp. 1345-1352
-
-
Tominaga, A.1
Takahashi, T.2
Kikuchi, Y.3
Mita, S.4
Naomi, S.5
Harada, N.6
Yamaguchi, N.7
Takatsu, K.8
-
51
-
-
0027155448
-
A novel dimer configuration revealed by the crystal structure at 2.4Å resolution of human interleukin-5
-
Milburn, M.V., Hassell, A.M., Lambert, M.H., Jordan, S.R., Proudfoot, A.E.I., Graber, P. and Wells, T.N.C. (1993) A novel dimer configuration revealed by the crystal structure at 2.4Å resolution of human interleukin-5. Nature 363, 172-176.
-
(1993)
Nature
, vol.363
, pp. 172-176
-
-
Milburn, M.V.1
Hassell, A.M.2
Lambert, M.H.3
Jordan, S.R.4
Proudfoot, A.E.I.5
Graber, P.6
Wells, T.N.C.7
-
52
-
-
0030062246
-
Creation of a biologically active interleukin-5 monomer
-
Dickason, R.R. and Huston, D.P. (1996) Creation of a biologically active interleukin-5 monomer. Nature 379, 652-655.
-
(1996)
Nature
, vol.379
, pp. 652-655
-
-
Dickason, R.R.1
Huston, D.P.2
-
53
-
-
0024353079
-
TH1 and TH2: different patterns of lympholine secretion lead to different functional properties
-
Mosmann, T.R. and Coffman, R.L. (1989) TH1 and TH2: different patterns of lympholine secretion lead to different functional properties. Annu. Rev. Immunol. 7, 145-173.
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 145-173
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
54
-
-
2442452544
-
The role of IL-5 for mature B-1 cells in homeostatic proliferation, cell survival, and Ig production
-
Moon, B.G., Takaki, S., Miyake, K. and Takatsu, K. (2004) The role of IL-5 for mature B-1 cells in homeostatic proliferation, cell survival, and Ig production. J. Immunol. 172, 6020-6029.
-
(2004)
J. Immunol.
, vol.172
, pp. 6020-6029
-
-
Moon, B.G.1
Takaki, S.2
Miyake, K.3
Takatsu, K.4
-
55
-
-
3442898788
-
+ Peyer's patch cells are a novel cell subset which secrete IL-5 in response to IL-2: implications for their role in IgA production
-
+ Peyer's patch cells are a novel cell subset which secrete IL-5 in response to IL-2: implications for their role in IgA production. Eur. J. Immunol. 34, 1920-1929.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1920-1929
-
-
Kuraoka, M.1
Hashiguchi, M.2
Hachimura, S.3
Kaminogawa, S.4
-
56
-
-
75749122181
-
+ lymphoid cells
-
+ lymphoid cells. Nature 463, 540-545.
-
(2010)
Nature
, vol.463
, pp. 540-545
-
-
Moro, K.1
Yamada, T.2
Tanabe, M.3
Takeuchi, T.4
Ikawa, T.5
Kawamoto, H.6
Furusawa, J.7
Ohtani, M.8
Fujii, H.9
Koyasu, S.10
-
57
-
-
82355183283
-
Interleuikn 5 and the interleukin 5 receptor
-
(eds. Lee, J.J. and Rosenberg, H.F.). Wiley, New York (in press)
-
Takatsu, K. (2011) Interleuikn 5 and the interleukin 5 receptor. In Eosinophils in Health and Diseases (eds. Lee, J.J. and Rosenberg, H.F.). Wiley, New York (in press).
-
(2011)
Eosinophils in Health and Diseases
-
-
Takatsu, K.1
-
58
-
-
0034885812
-
Strain dependence of airway hyperresponsiveness reflects differences in eosinophil localization in the lung
-
Takeda, K., Haczku, A., Lee, J.J., Irvin, C.G. and Gelfand, E.W. (2001) Strain dependence of airway hyperresponsiveness reflects differences in eosinophil localization in the lung. Am. J. Physiol. Lung Cell. Mol. Physiol. 281, L394-L402.
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.281
-
-
Takeda, K.1
Haczku, A.2
Lee, J.J.3
Irvin, C.G.4
Gelfand, E.W.5
-
59
-
-
34249653510
-
Strain-dependent resistance to allergen-induced lung pathophysiology in mice correlates with rate of apoptosis of lungderived eosinophils
-
Tumes, D.J., Cormie, J., Calvert, M.G., Stewart, K., Nassenstein, C., Armin Braun, A., Foster, P.S. and Dent, L.A. (2007) Strain-dependent resistance to allergen-induced lung pathophysiology in mice correlates with rate of apoptosis of lungderived eosinophils. J. Leukoc. Biol. 81, 1362-1373.
-
(2007)
J. Leukoc. Biol.
, vol.81
, pp. 1362-1373
-
-
Tumes, D.J.1
Cormie, J.2
Calvert, M.G.3
Stewart, K.4
Nassenstein, C.5
Armin Braun, A.6
Foster, P.S.7
Dent, L.A.8
-
60
-
-
0025021864
-
Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophilia
-
Samoszuk, M. and Nansen, L. (1990) Detection of interleukin-5 messenger RNA in Reed-Sternberg cells of Hodgkin's disease with eosinophilia. Blood 75, 13-16.
-
(1990)
Blood
, vol.75
, pp. 13-16
-
-
Samoszuk, M.1
Nansen, L.2
-
61
-
-
77957024366
-
Interleukin-5
-
(eds. LeRoith, D. and Bondy, C.). JAI Press, London
-
Takatsu, K., Dickason, R. and Huston, D. (1997) Interleukin-5. In Growth Factors and Cytokines in Health and Disease (eds. LeRoith, D. and Bondy, C.). JAI Press, London, pp. 143-200.
-
(1997)
Growth Factors and Cytokines in Health and Disease
, pp. 143-200
-
-
Takatsu, K.1
Dickason, R.2
Huston, D.3
-
62
-
-
0023676232
-
Receptors for T cell-replacing factor/interleukin 5. Specificity, quantitation, and its implication
-
Mita, S., Harada, N., Naomi, N., Hitoshi, Y., Sakamoto, K., Akagi, M., Tominaga, A. and Takatsu, K. (1988) Receptors for T cell-replacing factor/interleukin 5. Specificity, quantitation, and its implication. J. Exp. Med. 168, 863-878.
-
(1988)
J. Exp. Med.
, vol.168
, pp. 863-878
-
-
Mita, S.1
Harada, N.2
Naomi, N.3
Hitoshi, Y.4
Sakamoto, K.5
Akagi, M.6
Tominaga, A.7
Takatsu, K.8
-
63
-
-
0024558339
-
Characterization of highaffinity receptors for interleukin 5 on interleukin 5-dependent cell lines
-
Mita, S., Tominaga, A., Hitoshi, Y., Sakamoto, K., Honjo, T., Akagi, M., Kikuchi, Y., Yamaguchi, Y. and Takatsu, K. (1989) Characterization of highaffinity receptors for interleukin 5 on interleukin 5-dependent cell lines. Proc. Natl. Acad. Sci. U.S.A. 86, 2311-2315.
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 2311-2315
-
-
Mita, S.1
Tominaga, A.2
Hitoshi, Y.3
Sakamoto, K.4
Honjo, T.5
Akagi, M.6
Kikuchi, Y.7
Yamaguchi, Y.8
Takatsu, K.9
-
64
-
-
0025186581
-
Characterization of the murine interleukin 5 receptor by using a monoclonal antibody
-
Yamaguchi, N., Hitoshi, Y., Mita, S., Hosoya, Y., Kikuchi, Y., Tominaga, A. and Takatsu, K. (1990) Characterization of the murine interleukin 5 receptor by using a monoclonal antibody. Int. Immunol. 2, 181-187.
-
(1990)
Int. Immunol.
, vol.2
, pp. 181-187
-
-
Yamaguchi, N.1
Hitoshi, Y.2
Mita, S.3
Hosoya, Y.4
Kikuchi, Y.5
Tominaga, A.6
Takatsu, K.7
-
66
-
-
0024551061
-
Monoclonal antibodies reactive with the mouse interleukin 5 receptor
-
Rolink, A.G., Melchers, F. and Palacios, R. (1989) Monoclonal antibodies reactive with the mouse interleukin 5 receptor. J. Exp. Med. 169, 1693-1701.
-
(1989)
J. Exp. Med.
, vol.169
, pp. 1693-1701
-
-
Rolink, A.G.1
Melchers, F.2
Palacios, R.3
-
67
-
-
0025785246
-
Molecular characterization of the β chain of the murine interleukin-5 receptor
-
Mita, S., Takaki, S., Hitoshi, Y., Rolink, A.G., Tominaga, A., Yamaguchi, N. and Takatsu, K. (1991) Molecular characterization of the β chain of the murine interleukin-5 receptor. Int. Immunol. 3, 665-672.
-
(1991)
Int. Immunol.
, vol.3
, pp. 665-672
-
-
Mita, S.1
Takaki, S.2
Hitoshi, Y.3
Rolink, A.G.4
Tominaga, A.5
Yamaguchi, N.6
Takatsu, K.7
-
68
-
-
0025604276
-
Molecular cloning and expression of the murine interleukin-5 receptor
-
Takaki, S., Tominaga, A., Hitoshi, Y., Mita, S., Sonoda, E., Yamaguchi, N. and Takatsu, K. (1990) Molecular cloning and expression of the murine interleukin-5 receptor. EMBO J. 9, 4367-4374.
-
(1990)
EMBO J
, vol.9
, pp. 4367-4374
-
-
Takaki, S.1
Tominaga, A.2
Hitoshi, Y.3
Mita, S.4
Sonoda, E.5
Yamaguchi, N.6
Takatsu, K.7
-
69
-
-
0028117163
-
Cytokine signal transduction
-
Kishimoto, T., Taga, T. and Akira, S. (1994) Cytokine signal transduction. Cell 76, 253-262.
-
(1994)
Cell
, vol.76
, pp. 253-262
-
-
Kishimoto, T.1
Taga, T.2
Akira, S.3
-
70
-
-
0035066746
-
Functional dissection of the cytoplasmic subregions of the interleukin-5 receptor alpha chain in growth and immunoglobulin G1 switch recombination of B cells
-
Moon, B.G., Yoshida, T., Shiiba, M., Nakao, K., Katsuki, M., Takaki, S. and Takatsu, K. (2001) Functional dissection of the cytoplasmic subregions of the interleukin-5 receptor alpha chain in growth and immunoglobulin G1 switch recombination of B cells. Immunology 102, 289-300.
-
(2001)
Immunology
, vol.102
, pp. 289-300
-
-
Moon, B.G.1
Yoshida, T.2
Shiiba, M.3
Nakao, K.4
Katsuki, M.5
Takaki, S.6
Takatsu, K.7
-
71
-
-
0026505476
-
Molecular cloning and expression of the human interleukin-5 receptor
-
Murata, Y., Takaki, S., Migita, M., Kikuchi, Y., Tominaga, A. and Takatsu, K. (1992) Molecular cloning and expression of the human interleukin-5 receptor. J. Exp. Med. 175, 341-351.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 341-351
-
-
Murata, Y.1
Takaki, S.2
Migita, M.3
Kikuchi, Y.4
Tominaga, A.5
Takatsu, K.6
-
72
-
-
0025770219
-
A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF
-
Tavernier, J., Devos, R., Cornelis, S., Tuypens, T., Van der Heyden, J., Fiers, W. and Plaetinck, G. (1991) A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF. Cell 66, 1175-1184.
-
(1991)
Cell
, vol.66
, pp. 1175-1184
-
-
Tavernier, J.1
Devos, R.2
Cornelis, S.3
Tuypens, T.4
Van der Heyden, J.5
Fiers, W.6
Plaetinck, G.7
-
73
-
-
0029000927
-
Identication of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist
-
Tavernier, J., Tuypens, T., Verhee, A., Plaetinck, G., Devos, R., Van der Heyden, J., Guisez, Y. and Oefner, C. (1995) Identication of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist. Proc. Natl. Acad. Sci. U.S.A. 92, 5194-5198.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 5194-5198
-
-
Tavernier, J.1
Tuypens, T.2
Verhee, A.3
Plaetinck, G.4
Devos, R.5
Van der Heyden, J.6
Guisez, Y.7
Oefner, C.8
-
74
-
-
0026689408
-
Cytokine receptors and signal transduction
-
Miyajima, A., Kitamura, T., Harada, N., Yokota, T. and Arai, K. (1992) Cytokine receptors and signal transduction. Annu. Rev. Immunol. 10, 295-331.
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 295-331
-
-
Miyajima, A.1
Kitamura, T.2
Harada, N.3
Yokota, T.4
Arai, K.5
-
75
-
-
0025818263
-
Identification of the second subunit of the murine interleukin-5 receptor: interleukin-3 receptor-like protein. AIC2B is a component of the high affinity interleukin-5 receptor
-
Takaki, S., Mita, S., Kitamura, T., Yonehara, S., Yamaguchi, N., Tominaga, A., Miyajima, A. and Takatsu, K. (1991) Identification of the second subunit of the murine interleukin-5 receptor: interleukin-3 receptor-like protein, AIC2B is a component of the high affinity interleukin-5 receptor. EMBO J. 10, 2833-2838.
-
(1991)
EMBO J
, vol.10
, pp. 2833-2838
-
-
Takaki, S.1
Mita, S.2
Kitamura, T.3
Yonehara, S.4
Yamaguchi, N.5
Tominaga, A.6
Miyajima, A.7
Takatsu, K.8
-
76
-
-
0032055856
-
JAK2 and JAK1 constitutively associate with an interleukin 5 (IL-5) receptor and βc subunit, respectively and are activated upon IL-5 stimulation
-
Ogata, N., Kouro, T., Yamada, A., Koike, M., Hanai, N., Ishikawa, T. and Takatsu, K. (1998) JAK2 and JAK1 constitutively associate with an interleukin 5 (IL-5) receptor and βc subunit, respectively and are activated upon IL-5 stimulation. Blood 91, 2264-2271.
-
(1998)
Blood
, vol.91
, pp. 2264-2271
-
-
Ogata, N.1
Kouro, T.2
Yamada, A.3
Koike, M.4
Hanai, N.5
Ishikawa, T.6
Takatsu, K.7
-
77
-
-
0028113506
-
A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor α chain and its function in IL-5-mediated growth signal transduction
-
Takaki, S., Kanazawa, H., Shiiba, M. and Takatsu, K. (1994) A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor α chain and its function in IL-5-mediated growth signal transduction. Mol. Cell. Biol. 14, 7404-7413.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 7404-7413
-
-
Takaki, S.1
Kanazawa, H.2
Shiiba, M.3
Takatsu, K.4
-
78
-
-
0030048771
-
Critical proline residues of the cytoplasmic domain of the IL-5 receptor alpha chain and its function in IL-5-mediated activation of JAK kinase and STAT5
-
Kouro, T., Kikuchi, Y., Kanazawa, H., Hirokawa, K., Harada, N., Shiiba, M., Wakao, H., Takaki, S. and Takatsu, K. (1996) Critical proline residues of the cytoplasmic domain of the IL-5 receptor alpha chain and its function in IL-5-mediated activation of JAK kinase and STAT5. Int. Immunol. 8, 237-245.
-
(1996)
Int. Immunol.
, vol.8
, pp. 237-245
-
-
Kouro, T.1
Kikuchi, Y.2
Kanazawa, H.3
Hirokawa, K.4
Harada, N.5
Shiiba, M.6
Wakao, H.7
Takaki, S.8
Takatsu, K.9
-
79
-
-
0027155237
-
Reconstitution of the functional receptors for murine and human interleukin 5
-
Takaki, S., Murata, Y., Kitamura, T., Miyajima, A., Tominaga, A. and Takatsu, K. (1993) Reconstitution of the functional receptors for murine and human interleukin 5. J. Exp. Med. 177, 1523-1529.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1523-1529
-
-
Takaki, S.1
Murata, Y.2
Kitamura, T.3
Miyajima, A.4
Tominaga, A.5
Takatsu, K.6
-
80
-
-
77954597135
-
Two modes of beta-receptor recognition are mediated by distinct epitopes on mouse and human interleukin-3
-
Mirza, S., Chen, J., Wen, B., Ewens, C.L., Dai, J., Murphy, J.M. and Young, I.G. (2010) Two modes of beta-receptor recognition are mediated by distinct epitopes on mouse and human interleukin-3. J. Biol. Chem. 285, 22370-22381.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 22370-22381
-
-
Mirza, S.1
Chen, J.2
Wen, B.3
Ewens, C.L.4
Dai, J.5
Murphy, J.M.6
Young, I.G.7
-
81
-
-
45149114572
-
Interleukin-5 receptor subunit oligomerization and rearrangement revealed by fluorescence resonance energy transfer imaging
-
Zaks-Zilberman, M., Hamington, A.E., Ishino, T. and Chaikaen, I.M. (2008) Interleukin-5 receptor subunit oligomerization and rearrangement revealed by fluorescence resonance energy transfer imaging. J. Biol. Chem. 283, 13398-13406.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13398-13406
-
-
Zaks-Zilberman, M.1
Hamington, A.E.2
Ishino, T.3
Chaikaen, I.M.4
-
82
-
-
0035542919
-
Proteasome regulation of βc signaling reveals a novel mechanism for heterotypic desensitization
-
Martinez-Moczygemba, M. and Huston, D.P. (2001) Proteasome regulation of βc signaling reveals a novel mechanism for heterotypic desensitization. J. Clin. Invest. 108, 1797-1806.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1797-1806
-
-
Martinez-Moczygemba, M.1
Huston, D.P.2
-
83
-
-
0027329865
-
Interleukin-5 receptor positive B cells, but not eosinophils are functionally and numerically influenced in the mice carried with X-linked immunodeficiency
-
Hitoshi, Y., Sonoda, E., Kikuchi, Y., Yonehara, S., Nakauchi, H., Tominaga, A. and Takatsu, K. (1993) Interleukin-5 receptor positive B cells, but not eosinophils are functionally and numerically influenced in the mice carried with X-linked immunodeficiency. Int. Immunol. 5, 1183-1190.
-
(1993)
Int. Immunol.
, vol.5
, pp. 1183-1190
-
-
Hitoshi, Y.1
Sonoda, E.2
Kikuchi, Y.3
Yonehara, S.4
Nakauchi, H.5
Tominaga, A.6
Takatsu, K.7
-
84
-
-
0026016424
-
Transgenic mice expressing a B cell growth and differentiation factor gene (interleukin 5) develop eosinophilia and autoantibody production
-
Tominaga, A., Takaki, S., Koyama, N., Katoh, S., Matsumoto, R., Migita, M., Hitoshi, Y., Hosoya, Y., Yamauchi, S., Kanai, Y., Miyazaki, J.-I., Usuku, G., Yamamura, K.-I. and Takatsu, K. (1991) Transgenic mice expressing a B cell growth and differentiation factor gene (interleukin 5) develop eosinophilia and autoantibody production. J. Exp. Med. 173, 429-437.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 429-437
-
-
Tominaga, A.1
Takaki, S.2
Koyama, N.3
Katoh, S.4
Matsumoto, R.5
Migita, M.6
Hitoshi, Y.7
Hosoya, Y.8
Yamauchi, S.9
Kanai, Y.10
Miyazaki, J.-I.11
Usuku, G.12
Yamamura, K.-I.13
Takatsu, K.14
-
85
-
-
16044375187
-
Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R, -deficient mice
-
Yoshida, T., Ikuta, K., Sugaya, H., Maki, K., Takagi, M., Kanazawa, H., Sunaga, S., Kinashi, T., Yoshimura, K., Miyazaki, J., Takaki, S. and Takatsu, K. (1996) Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R,-deficient mice. Immunity 4, 483-494.
-
(1996)
Immunity
, vol.4
, pp. 483-494
-
-
Yoshida, T.1
Ikuta, K.2
Sugaya, H.3
Maki, K.4
Takagi, M.5
Kanazawa, H.6
Sunaga, S.7
Kinashi, T.8
Yoshimura, K.9
Miyazaki, J.10
Takaki, S.11
Takatsu, K.12
-
86
-
-
0033556253
-
Deficiency of IL-5 receptor, -chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues
-
Hiroi, T., Yanagita, M., Iijima, H., Iwatani, K., Yoshida, T., Takatsu, K. and Kiyono, H. (1999) Deficiency of IL-5 receptor,-chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues. J. Immunol. 162, 821-828.
-
(1999)
J. Immunol.
, vol.162
, pp. 821-828
-
-
Hiroi, T.1
Yanagita, M.2
Iijima, H.3
Iwatani, K.4
Yoshida, T.5
Takatsu, K.6
Kiyono, H.7
-
87
-
-
67349122298
-
Expression of IL-5R, on B-1 cell progenitors in mouse fetal liver and involvement of Bruton's tyrosine kinase in their development
-
Kouro, T., Ikutani, M., Kariyone, A. and Takatsu, K. (2009) Expression of IL-5R, on B-1 cell progenitors in mouse fetal liver and involvement of Bruton's tyrosine kinase in their development. Immunol. Lett. 123, 169-178.
-
(2009)
Immunol. Lett.
, vol.123
, pp. 169-178
-
-
Kouro, T.1
Ikutani, M.2
Kariyone, A.3
Takatsu, K.4
-
88
-
-
39549120410
-
Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells
-
Emslie, D., D'Costa, K., Hasbold, J., Metcalf, D., Takatsu, K., Hodgkin, P.O. and Corcoran, L.M. (2008) Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells. J. Exp. Med. 205, 409-421.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 409-421
-
-
Emslie, D.1
D'Costa, K.2
Hasbold, J.3
Metcalf, D.4
Takatsu, K.5
Hodgkin, P.O.6
Corcoran, L.M.7
-
89
-
-
0028673423
-
Interleukin-5 and its receptor system in the immune system and inflammation
-
Takatsu, K., Kouro, T. and Nagai, Y. (2009) Interleukin-5 and its receptor system in the immune system and inflammation. Adv. Immunol. 57, 145-190.
-
(2009)
Adv. Immunol.
, vol.57
, pp. 145-190
-
-
Takatsu, K.1
Kouro, T.2
Nagai, Y.3
-
91
-
-
22344443951
-
Identification of eosinophil lineage-committed progenitors in the murine bone marrow
-
Iwasaki, H., Mizuno, S., Mayfield, R., Shigematsu, H., Arinobu, Y., Seed, B., Gurish, M.F., Takatsu, K. and Akashi, K. (2005) Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J. Exp. Med. 201, 1891-1897.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1891-1897
-
-
Iwasaki, H.1
Mizuno, S.2
Mayfield, R.3
Shigematsu, H.4
Arinobu, Y.5
Seed, B.6
Gurish, M.F.7
Takatsu, K.8
Akashi, K.9
-
92
-
-
0028809201
-
Identification and characterization of a functional promoter region in the human eosinophil IL-5 receptor alpha subunit gene
-
Sun, Z., Yergeau, D.A., Tuypens, T., Tavernier, J., Paul, C.C., Baumann, M.A., Tenen, D.G. and Ackerman, S.J. (1995) Identification and characterization of a functional promoter region in the human eosinophil IL-5 receptor alpha subunit gene. J. Biol. Chem. 270, 1462-1471.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 1462-1471
-
-
Sun, Z.1
Yergeau, D.A.2
Tuypens, T.3
Tavernier, J.4
Paul, C.C.5
Baumann, M.A.6
Tenen, D.G.7
Ackerman, S.J.8
-
93
-
-
0033049420
-
Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains
-
Iwama, A., Pan, J., Zhang, P., Reith, W., Mach, B., Tenen, D.G. and Sun, Z. (1999) Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains. Mol. Cell. Biol. 19, 3940-3950.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3940-3950
-
-
Iwama, A.1
Pan, J.2
Zhang, P.3
Reith, W.4
Mach, B.5
Tenen, D.G.6
Sun, Z.7
-
94
-
-
0028114191
-
IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus-2 kinases
-
Satoh, S., Katagiri, T., Takaki, S., Kikuchi, Y., Hitoshi, Y., Yonehara, S., Tsukada, S., Kitamura, D., Watanabe, T., Witte, O.N. and Takatsu, K. (1995) IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus-2 kinases. J. Exp. Med. 180, 2101-2111.
-
(1995)
J. Exp. Med.
, vol.180
, pp. 2101-2111
-
-
Satoh, S.1
Katagiri, T.2
Takaki, S.3
Kikuchi, Y.4
Hitoshi, Y.5
Yonehara, S.6
Tsukada, S.7
Kitamura, D.8
Watanabe, T.9
Witte, O.N.10
Takatsu, K.11
-
95
-
-
0032029609
-
Interleukin 5 and B cell differentiation
-
Takatsu, K. (1998) Interleukin 5 and B cell differentiation. Cytokine Growth Factor Rev. 9, 25-35.
-
(1998)
Cytokine Growth Factor Rev.
, vol.9
, pp. 25-35
-
-
Takatsu, K.1
-
96
-
-
0033802576
-
IL-5-Induced JAB-JAK2 interaction
-
Zahn, S., Godillot, P., Yoshimura, A. and Chaiken, I. (2000) IL-5-Induced JAB-JAK2 interaction. Cytokine 12, 299-306.
-
(2000)
Cytokine
, vol.12
, pp. 299-306
-
-
Zahn, S.1
Godillot, P.2
Yoshimura, A.3
Chaiken, I.4
-
97
-
-
0035500292
-
Essential role of Stat5 for IL-5-dependent IgH switch recombination in mouse B cells
-
Horikawa, K., Kaku, H., Nakajima, H., Davey, H.W., Hennighausen, L., Iwamoto, I., Yasue, T., Kariyone, A. and Takatsu, K. (2001) Essential role of Stat5 for IL-5-dependent IgH switch recombination in mouse B cells. J. Immunol. 167, 5018-5026.
-
(2001)
J. Immunol.
, vol.167
, pp. 5018-5026
-
-
Horikawa, K.1
Kaku, H.2
Nakajima, H.3
Davey, H.W.4
Hennighausen, L.5
Iwamoto, I.6
Yasue, T.7
Kariyone, A.8
Takatsu, K.9
-
98
-
-
33750561324
-
JAK1 N-terminus binds to conserved Box 1 and Box 2 motifs of cytokine receptor common beta subunit but signal activation requires JAK1 Cterminus
-
Huang, H.M., Lee, Y.L. and Chang, T.W. (2006) JAK1 N-terminus binds to conserved Box 1 and Box 2 motifs of cytokine receptor common beta subunit but signal activation requires JAK1 Cterminus. J. Cell. Biochem. 99, 1078-1084.
-
(2006)
J. Cell. Biochem.
, vol.99
, pp. 1078-1084
-
-
Huang, H.M.1
Lee, Y.L.2
Chang, T.W.3
-
99
-
-
0034651636
-
Both Stat5a and Stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue
-
Kagami, S., Nakajima, H., Kumano, K., Suzuki, K., Suto, A., Imada, K., Davey, H.W., Saito, Y., Takatsu, K., Leonard, W.J. and Iwamoto, I. (2000) Both Stat5a and Stat5b are required for antigen-induced eosinophil and T-cell recruitment into the tissue. Blood 95, 1370-1377.
-
(2000)
Blood
, vol.95
, pp. 1370-1377
-
-
Kagami, S.1
Nakajima, H.2
Kumano, K.3
Suzuki, K.4
Suto, A.5
Imada, K.6
Davey, H.W.7
Saito, Y.8
Takatsu, K.9
Leonard, W.J.10
Iwamoto, I.11
-
100
-
-
77956410301
-
A novel TNF receptor-associated factor 6 binding domain mediates NF-5B signaling by the common cytokine receptor beta subunit
-
Meads, M.B., Li, Z.W. and Dalton, W.S. (2010) A novel TNF receptor-associated factor 6 binding domain mediates NF-5B signaling by the common cytokine receptor beta subunit. J. Immunol. 185, 1606-1615.
-
(2010)
J. Immunol.
, vol.185
, pp. 1606-1615
-
-
Meads, M.B.1
Li, Z.W.2
Dalton, W.S.3
-
101
-
-
33947635579
-
JAK kinases control IL-5 receptor ubiquitination, degradation and internalization
-
Martinez-Moczygemba, M., Huston, D.P. and Lei, J.T. (2007) JAK kinases control IL-5 receptor ubiquitination, degradation and internalization. J. Leukoc. Biol. 81, 1137-1148.
-
(2007)
J. Leukoc. Biol.
, vol.81
, pp. 1137-1148
-
-
Martinez-Moczygemba, M.1
Huston, D.P.2
Lei, J.T.3
-
102
-
-
0027399081
-
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
-
Tsukada, S., Saffran, D.C., Rawling, D.J., Parolini, O., Allen, R.C., Klisak, I., Sparkes, R.S., Kubagawa, H., Mohandas, T., Quan, S., Belmont, J.W., Cooper, M.D., Conley, M.E. and Witte, N. (1993) Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell 72, 279-290.
-
(1993)
Cell
, vol.72
, pp. 279-290
-
-
Tsukada, S.1
Saffran, D.C.2
Rawling, D.J.3
Parolini, O.4
Allen, R.C.5
Klisak, I.6
Sparkes, R.S.7
Kubagawa, H.8
Mohandas, T.9
Quan, S.10
Belmont, J.W.11
Cooper, M.D.12
Conley, M.E.13
Witte, N.14
-
103
-
-
0030985414
-
A critical role of Lyn and Fyn for B cell responses to CD38 ligation and interleukin 5
-
Yasue, T., Nishizumi, H., Aizawa, S., Yamamoto, T., Miyake, K., Mizoguchi, C., Uehara, S., Kikuchi, Y. and Takatsu, K. (1997) A critical role of Lyn and Fyn for B cell responses to CD38 ligation and interleukin 5. Proc. Natl. Acad. Sci. U.S.A. 94, 10307-10312.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 10307-10312
-
-
Yasue, T.1
Nishizumi, H.2
Aizawa, S.3
Yamamoto, T.4
Miyake, K.5
Mizoguchi, C.6
Uehara, S.7
Kikuchi, Y.8
Takatsu, K.9
-
104
-
-
0033819990
-
Identification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse Btk
-
Kikuchi, Y., Hirano, M., Seto, M. and Takatsu, K. (2000) Identification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse Btk. Int. Immunol. 12, 1397-1408.
-
(2000)
Int. Immunol.
, vol.12
, pp. 1397-1408
-
-
Kikuchi, Y.1
Hirano, M.2
Seto, M.3
Takatsu, K.4
-
105
-
-
2442548829
-
Bruton's tyrosine kinase (Btk) enhances transcriptional co-activation activity of BAM11, a Btk-associated molecule of a subunit of SWI/SNF complexes
-
Hirano, M., Kikuchi, Y., Nisitani, S., Yamaguchi, A., Sato, A., Ito, T., Iba, H. and Takatsu, K. (2004) Bruton's tyrosine kinase (Btk) enhances transcriptional co-activation activity of BAM11, a Btk-associated molecule of a subunit of SWI/SNF complexes. Int. Immunol. 16, 747-757.
-
(2004)
Int. Immunol.
, vol.16
, pp. 747-757
-
-
Hirano, M.1
Kikuchi, Y.2
Nisitani, S.3
Yamaguchi, A.4
Sato, A.5
Ito, T.6
Iba, H.7
Takatsu, K.8
-
106
-
-
0028956998
-
The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathway
-
Pazdrak, K., Schreiber, D., Forsythe, P., Justement, L. and Alam, R. (1995) The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathway. J. Exp. Med. 181, 1827-1834.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 1827-1834
-
-
Pazdrak, K.1
Schreiber, D.2
Forsythe, P.3
Justement, L.4
Alam, R.5
-
107
-
-
19944433253
-
Spred-1 negatively regulates allergen-induced airway eosinophilia and hyperresponsiveness
-
Inoue, H., Kato, R., Fukuyama, S., Nonami, A., Taniguchi, K., Matsumoto, K., Nakano, T., Tsuda, M., Matsumura, M., Kubo, M., Ishikawa, F., Moon, B.-G., Takatsu, K., Nakanishi, Y. and Yoshimura, A. (2005) Spred-1 negatively regulates allergen-induced airway eosinophilia and hyperresponsiveness. J. Exp. Med. 201, 73-82.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 73-82
-
-
Inoue, H.1
Kato, R.2
Fukuyama, S.3
Nonami, A.4
Taniguchi, K.5
Matsumoto, K.6
Nakano, T.7
Tsuda, M.8
Matsumura, M.9
Kubo, M.10
Ishikawa, F.11
Moon, B.-G.12
Takatsu, K.13
Nakanishi, Y.14
Yoshimura, A.15
-
108
-
-
2542442633
-
Transcriptional control of early B cell development
-
Busslinger, M. (2004) Transcriptional control of early B cell development. Annu. Rev. Immunol. 22, 55-79.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 55-79
-
-
Busslinger, M.1
-
109
-
-
0024445451
-
Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production
-
Sonoda, E., Matsumoto, R., Hitoshi, Y., Mita, S., Ishii, N., Sugimoto, M., Araki, S., Tominaga, A., Yamaguchi, N. and Takatsu, K. (1989) Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production. J. Exp. Med. 170, 1415-1420.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 1415-1420
-
-
Sonoda, E.1
Matsumoto, R.2
Hitoshi, Y.3
Mita, S.4
Ishii, N.5
Sugimoto, M.6
Araki, S.7
Tominaga, A.8
Yamaguchi, N.9
Takatsu, K.10
-
110
-
-
40949133684
-
A memoir of AID, which engraves antibody memory on DNA
-
Honjo, T. (2008) A memoir of AID, which engraves antibody memory on DNA. Nat. Immunol. 9, 335-337.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 335-337
-
-
Honjo, T.1
-
111
-
-
0037108463
-
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
-
Rada, C., Williams, G.T., Nilsen, H., Barnes, D.E., Lindahl, T. and Neuberger, M.S. (2002) Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr. Biol. 12, 1748-1755.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1748-1755
-
-
Rada, C.1
Williams, G.T.2
Nilsen, H.3
Barnes, D.E.4
Lindahl, T.5
Neuberger, M.S.6
-
112
-
-
0033105843
-
IL-5 induces IgG1 isotype switch recombination in mouse CD38-activated sIgDpositive B lymphocytes
-
Mizoguchi, C., Uehara, S., Akira, S. and Takatsu, K. (1999) IL-5 induces IgG1 isotype switch recombination in mouse CD38-activated sIgDpositive B lymphocytes. J. Immunol. 162, 2812-2819.
-
(1999)
J. Immunol.
, vol.162
, pp. 2812-2819
-
-
Mizoguchi, C.1
Uehara, S.2
Akira, S.3
Takatsu, K.4
-
113
-
-
0036708597
-
NF-5B is required for CD38-mediated induction of C.1 germline transcripts in murine B lymphocytes
-
Kaku, H., Horikawa, K., Obata, Y., Kato, I., Okamoto, H., Sakaguchi, N., Gerondakis, S. and Takatsu, K. (2002) NF-5B is required for CD38-mediated induction of C.1 germline transcripts in murine B lymphocytes. Int. Immunol. 14, 1055-1064.
-
(2002)
Int. Immunol.
, vol.14
, pp. 1055-1064
-
-
Kaku, H.1
Horikawa, K.2
Obata, Y.3
Kato, I.4
Okamoto, H.5
Sakaguchi, N.6
Gerondakis, S.7
Takatsu, K.8
-
114
-
-
33746054494
-
Interleukin-5 regulates genes involved in B cell terminal maturation
-
Horikawa, K. and Takatsu, K. (2006) Interleukin-5 regulates genes involved in B cell terminal maturation. Immunology 118, 497-508.
-
(2006)
Immunology
, vol.118
, pp. 497-508
-
-
Horikawa, K.1
Takatsu, K.2
-
115
-
-
24644522929
-
Requirement of 8-mercaptoguanosine as a costimulus for IL-4-dependent 7 to .1 class switch recombination in CD38-activated B cells
-
Tsukamoto, Y., Uehara, S., Mizoguchi, C., Sato, A., Horikawa, K. and Takatsu, K. (2005) Requirement of 8-mercaptoguanosine as a costimulus for IL-4-dependent 7 to .1 class switch recombination in CD38-activated B cells. Biochem. Biophys. Res. Commun. 336, 625-633.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.336
, pp. 625-633
-
-
Tsukamoto, Y.1
Uehara, S.2
Mizoguchi, C.3
Sato, A.4
Horikawa, K.5
Takatsu, K.6
-
116
-
-
82355183278
-
Toll-like receptor 7 cooperates with antigen receptors and CD38 for induction of class switch recombination and terminal B cell maturation
-
Tsukamoto, Y., Nagai, Y., Kaisho, T., Akira, S., Miyake, K. and Takatsu, K. (2009) Toll-like receptor 7 cooperates with antigen receptors and CD38 for induction of class switch recombination and terminal B cell maturation. Mol. Immunol. 46, 1276-1288.
-
(2009)
Mol. Immunol.
, vol.46
, pp. 1276-1288
-
-
Tsukamoto, Y.1
Nagai, Y.2
Kaisho, T.3
Akira, S.4
Miyake, K.5
Takatsu, K.6
-
118
-
-
0034041358
-
Allergeninduced airway inflammation and bronchial responsiveness in interleukin-5 receptor α chaindeficient mice
-
Tanaka, H., Kawada, N., Yamada, T., Kawada, K., Takatsu, K. and Nagai, H. (2000) Allergeninduced airway inflammation and bronchial responsiveness in interleukin-5 receptor α chaindeficient mice. Clin. Exp. Allergy 30, 874-881.
-
(2000)
Clin. Exp. Allergy
, vol.30
, pp. 874-881
-
-
Tanaka, H.1
Kawada, N.2
Yamada, T.3
Kawada, K.4
Takatsu, K.5
Nagai, H.6
-
119
-
-
13344277358
-
+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses
-
+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 4, 15-24.
-
(1996)
Immunity
, vol.4
, pp. 15-24
-
-
Kopf, M.1
Brombacher, F.2
Hodgkin, P.D.3
Rumsay, A.J.4
Milbourne, E.A.5
Dai, W.J.6
Ovington, K.S.7
Behm, C.A.8
Kohler, G.9
Young, I.G.10
Matthaei, K.I.11
-
120
-
-
0026683014
-
+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea
-
+ T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea. Am. Rev. Respir. Dis. 146, 374-377.
-
(1992)
Am. Rev. Respir. Dis.
, vol.146
, pp. 374-377
-
-
Nakajima, H.1
Iwamoto, I.2
Tomoe, S.3
Matsumura, R.4
Tomioka, H.5
Takatsu, K.6
Yoshida, S.7
-
121
-
-
0028987403
-
Antibody against interleukin-5 prevents antigen-induced eosinophil infiltration and bronchial hyper- reactivity in the guinea pig airways
-
Akutsu, I., Kojima, T., Kariyone, A., Fukuda, T., Makino, S. and Takatsu, K. (1995) Antibody against interleukin-5 prevents antigen-induced eosinophil infiltration and bronchial hyper- reactivity in the guinea pig airways. Immunol. Lett. 45, 109-116.
-
(1995)
Immunol. Lett.
, vol.45
, pp. 109-116
-
-
Akutsu, I.1
Kojima, T.2
Kariyone, A.3
Fukuda, T.4
Makino, S.5
Takatsu, K.6
-
122
-
-
0029146701
-
Effects of an antibody to IL-5 in a monkey model of asthma
-
Mauser, P.J., Pitman, A.M., Fernandez, X., Foran, S.K., Adams, G.K. III, Kreutner, W. and Chapman, R.W. (1995) Effects of an antibody to IL-5 in a monkey model of asthma. Am. J. Respir. Crit. Care Med. 152, 467-472.
-
(1995)
Am. J. Respir. Crit. Care Med.
, vol.152
, pp. 467-472
-
-
Mauser, P.J.1
Pitman, A.M.2
Fernandez, X.3
Foran, S.K.4
Adams III, G.K.5
Kreutner, W.6
Chapman, R.W.7
-
123
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
Leckie, M.J., ten Brinke, A., Khan, J., Diamant, Z., O'Connor, B.J., Walls, C.M., Mathur, A.K., Cowley, H.C., Chung, K.F., Djukanovic, R., Hansel, T.T., Holgate, S.T., Sterk, P.J. and Barnes, P.J. (2000) Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 356, 2144-2148.
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
ten Brinke, A.2
Khan, J.3
Diamant, Z.4
O'Connor, B.J.5
Walls, C.M.6
Mathur, A.K.7
Cowley, H.C.8
Chung, K.F.9
Djukanovic, R.10
Hansel, T.T.11
Holgate, S.T.12
Sterk, P.J.13
Barnes, P.J.14
-
124
-
-
36749065556
-
International Mepolizumab Study Group: A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma
-
Flood-Page, P., Swenson, C., Faiferman, I., Matthews, J., Williams, M., Brannick, L., Robinson, D., Wenzel, S., Busse, W., Hansel, T.T. and Barnes, N.C. (2007) International Mepolizumab Study Group: A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma. Am. J. Respir. Crit. Care Med. 176, 1062-1071.
-
(2007)
Am. J. Respir. Crit. Care Med.
, vol.176
, pp. 1062-1071
-
-
Flood-Page, P.1
Swenson, C.2
Faiferman, I.3
Matthews, J.4
Williams, M.5
Brannick, L.6
Robinson, D.7
Wenzel, S.8
Busse, W.9
Hansel, T.T.10
Barnes, N.C.11
-
126
-
-
40949146020
-
Treatment of patients with the hypereosinophilic syndrome with mepolizumab
-
and Mepolizumab HES Study Group
-
Rothenberg, M.E., Klion, A.D., Roufosse, F.E., Kahn, E.J., Weller, P.F., Simon, H-U., Schwartz, L.B., Rosenwasser, L.J., Ring, J., Griffin, E.F., Haig, A.E., Frewer, P.I.H., Parkin, J.M., Gleich, G.J. and Mepolizumab HES Study Group (2008) Treatment of patients with the hypereosinophilic syndrome with mepolizumab. N. Engl. J. Med. 358, 1215-1228.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1215-1228
-
-
Rothenberg, M.E.1
Klion, A.D.2
Roufosse, F.E.3
Kahn, E.J.4
Weller, P.F.5
Simon, H.-U.6
Schwartz, L.B.7
Rosenwasser, L.J.8
Ring, J.9
Griffin, E.F.10
Haig, A.E.11
Frewer, P.I.H.12
Parkin, J.M.13
Gleich, G.J.14
-
127
-
-
67249158818
-
Establishment of humanized anti-interleukin-5 receptor alpha chain monoclonal antibodies having a potent neutralizing activity
-
Koike, M., Nakamura, K., Furuya, A., Iida, A., Anazawa, H., Takatsu, K. and Hanai, N. (2009) Establishment of humanized anti-interleukin-5 receptor alpha chain monoclonal antibodies having a potent neutralizing activity. Hum. Antibodies 18, 17-27.
-
(2009)
Hum. Antibodies
, vol.18
, pp. 17-27
-
-
Koike, M.1
Nakamura, K.2
Furuya, A.3
Iida, A.4
Anazawa, H.5
Takatsu, K.6
Hanai, N.7
-
128
-
-
0037474276
-
The absence of fucose but not the presence of galactose or bisecting Nacetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity
-
Shinkawa, T., Nakamura, K., Yamane, N., Shoji-Hosaka, E., Kanda, Y., Sakurada, M., Uchida, K., Anazawa, H., Satoh, M., Yamasaki, M., Hanai, N. and Shitara, K. (2003) The absence of fucose but not the presence of galactose or bisecting Nacetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicity. J. Biol. Chem. 278, 3466-3473.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 3466-3473
-
-
Shinkawa, T.1
Nakamura, K.2
Yamane, N.3
Shoji-Hosaka, E.4
Kanda, Y.5
Sakurada, M.6
Uchida, K.7
Anazawa, H.8
Satoh, M.9
Yamasaki, M.10
Hanai, N.11
Shitara, K.12
-
129
-
-
77952733788
-
MEDI-563, a humanized anti-IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function
-
Kolbeck, R., Alexander Kozhich, A., Koike, M., Peng, L., Andersson, C.K., Damschroder, M.M., Reed, J.L., Woods, R., Dall'Acqua, W.W., Stephens, G.L., Erjefalt, J.S., Bjermer, L., Humbles, A.A., Gossage, D., Wu, H., Kiener, P.A., Spitalny, G.L., Mackay, C.R., Molfino, N.A. and Coyle, A.J. (2010) MEDI-563, a humanized anti-IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function. J. Allergy Clin. Immunol. 125, 1344-1353.
-
(2010)
J. Allergy Clin. Immunol.
, vol.125
, pp. 1344-1353
-
-
Kolbeck, R.1
Alexander Kozhich, A.2
Koike, M.3
Peng, L.4
Andersson, C.K.5
Damschroder, M.M.6
Reed, J.L.7
Woods, R.8
Dall'Acqua, W.W.9
Stephens, G.L.10
Erjefalt, J.S.11
Bjermer, L.12
Humbles, A.A.13
Gossage, D.14
Wu, H.15
Kiener, P.A.16
Spitalny, G.L.17
Mackay, C.R.18
Molfino, N.A.19
Coyle, A.J.20
more..
-
130
-
-
77952683218
-
Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor α antibody, in a phase I study of subjects with mild asthma
-
Busse, W.W., Katial, R., Gossage, D., Sari, S., Wang, B., Kolbeck, R., Coyle, A.J., Koike, M., Spitalny, G.L., Kiener, P.A., Geba, G.P. and Molfino, N.A. (2010) Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor α antibody, in a phase I study of subjects with mild asthma. J. Allergy Clin. Immunol. 125, 1237-1244.
-
(2010)
J. Allergy Clin. Immunol.
, vol.125
, pp. 1237-1244
-
-
Busse, W.W.1
Katial, R.2
Gossage, D.3
Sari, S.4
Wang, B.5
Kolbeck, R.6
Coyle, A.J.7
Koike, M.8
Spitalny, G.L.9
Kiener, P.A.10
Geba, G.P.11
Molfino, N.A.12
|