-
1
-
-
48749084893
-
Genome-wide association studies: A new window into immune-mediated diseases
-
R.J. Xavier, and J.D. Rioux Genome-wide association studies: a new window into immune-mediated diseases Nat Rev Immunol 8 2008 631 643
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 631-643
-
-
Xavier, R.J.1
Rioux, J.D.2
-
2
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
J.C. Barrett, S. Hansoul, D.L. Nicolae, J.H. Cho, R.H. Duerr, and J.D. Rioux Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease Nat Genet 40 2008 955 962
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
Rioux, J.D.6
-
3
-
-
77950298959
-
Genome-wide association identifies multiple ulcerative colitis susceptibility loci [published erratum in: Nat Genet 2011;43:388]
-
D.P. McGovern, A. Gardet, L. Törkvist, P. Goyette, J. Essers, and K.D. Taylor Genome-wide association identifies multiple ulcerative colitis susceptibility loci [published erratum in: Nat Genet 2011;43:388] Nat Genet 42 2010 332 337
-
(2010)
Nat Genet
, vol.42
, pp. 332-337
-
-
McGovern, D.P.1
Gardet, A.2
Törkvist, L.3
Goyette, P.4
Essers, J.5
Taylor, K.D.6
-
5
-
-
77951926420
-
Etiology of type 1 diabetes
-
J.A. Todd Etiology of type 1 diabetes Immunity 32 2010 457 467
-
(2010)
Immunity
, vol.32
, pp. 457-467
-
-
Todd, J.A.1
-
6
-
-
77951891703
-
Prediction and pathogenesis in type 1 diabetes
-
A.G. Ziegler, and G.T. Nepom Prediction and pathogenesis in type 1 diabetes Immunity 32 2010 468 478
-
(2010)
Immunity
, vol.32
, pp. 468-478
-
-
Ziegler, A.G.1
Nepom, G.T.2
-
7
-
-
70450193472
-
Human genetics illuminates the paths to metabolic disease
-
S. O'Rahilly Human genetics illuminates the paths to metabolic disease Nature 462 2009 307 314
-
(2009)
Nature
, vol.462
, pp. 307-314
-
-
O'Rahilly, S.1
-
8
-
-
78650166819
-
Genome-wide association scan allowing for epistasis in type 2 diabetes
-
J.T. Bell, N.J. Timpson, N.W. Rayner, E. Zeggini, T.M. Frayling, and A.T. Hattersley Genome-wide association scan allowing for epistasis in type 2 diabetes Ann Hum Genet 75 2011 10 19
-
(2011)
Ann Hum Genet
, vol.75
, pp. 10-19
-
-
Bell, J.T.1
Timpson, N.J.2
Rayner, N.W.3
Zeggini, E.4
Frayling, T.M.5
Hattersley, A.T.6
-
9
-
-
78649842241
-
Genomics, type 2 diabetes, and obesity
-
M.I. McCarthy Genomics, type 2 diabetes, and obesity N Engl J Med 363 2010 2339 2350
-
(2010)
N Engl J Med
, vol.363
, pp. 2339-2350
-
-
McCarthy, M.I.1
-
10
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
M.F. Moffatt, I.G. Gut, F. Demenais, D.P. Strachan, E. Bouzigon, and S. Heath A large-scale, consortium-based genomewide association study of asthma N Engl J Med 363 2010 1211 1221
-
(2010)
N Engl J Med
, vol.363
, pp. 1211-1221
-
-
Moffatt, M.F.1
Gut, I.G.2
Demenais, F.3
Strachan, D.P.4
Bouzigon, E.5
Heath, S.6
-
12
-
-
84975804424
-
1000 Genomes Project. Mapping copy number variation by population-scale genome sequencing
-
R.E. Mills, K. Walter, C. Stewart, R.E. Handsaker, K. Chen, and C. Alkan 1000 Genomes Project. Mapping copy number variation by population-scale genome sequencing Nature 470 2011 59 65
-
(2011)
Nature
, vol.470
, pp. 59-65
-
-
Mills, R.E.1
Walter, K.2
Stewart, C.3
Handsaker, R.E.4
Chen, K.5
Alkan, C.6
-
13
-
-
77957970301
-
Epigenetic modifications and human disease
-
A. Portela, and M. Esteller Epigenetic modifications and human disease Nat Biotechnol 28 2010 1057 1068
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1057-1068
-
-
Portela, A.1
Esteller, M.2
-
14
-
-
55949137722
-
Persistent epigenetic differences associated with prenatal exposure to famine in humans
-
B.T. Heijmans, E.W. Tobi, A.D. Stein, H. Putter, G.J. Blauw, and E.S. Susser Persistent epigenetic differences associated with prenatal exposure to famine in humans Proc Natl Acad Sci U S A 105 2008 17046 17049
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 17046-17049
-
-
Heijmans, B.T.1
Tobi, E.W.2
Stein, A.D.3
Putter, H.4
Blauw, G.J.5
Susser, E.S.6
-
15
-
-
58849118836
-
Epigenetic control of FOXP3 expression: The key to a stable regulatory T-cell lineage?
-
J. Huehn, J.K. Polansky, and A. Hamann Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage? Nat Rev Immunol 9 2009 83 89
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 83-89
-
-
Huehn, J.1
Polansky, J.K.2
Hamann, A.3
-
16
-
-
58849092225
-
Epigenetic control of T-helper-cell differentiation
-
C.B. Wilson, E. Rowell, and M. Sekimata Epigenetic control of T-helper-cell differentiation Nat Rev Immunol 9 2009 91 105
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 91-105
-
-
Wilson, C.B.1
Rowell, E.2
Sekimata, M.3
-
17
-
-
69749111973
-
Asthma and pregnancy: Emerging evidence of epigenetic interactions in utero
-
S.L. Prescott, and V. Clifton Asthma and pregnancy: emerging evidence of epigenetic interactions in utero Curr Opin Allergy Clin Immunol 9 2009 417 426
-
(2009)
Curr Opin Allergy Clin Immunol
, vol.9
, pp. 417-426
-
-
Prescott, S.L.1
Clifton, V.2
-
18
-
-
77957037314
-
MicroRNA as a new immune-regulatory agent in breast milk
-
N. Kosaka, H. Izumi, K. Sekine, and T. Ochiya microRNA as a new immune-regulatory agent in breast milk Silence 1 2010 7
-
(2010)
Silence
, vol.1
, pp. 7
-
-
Kosaka, N.1
Izumi, H.2
Sekine, K.3
Ochiya, T.4
-
19
-
-
77950365906
-
Nonresolving inflammation
-
C. Nathan, and A. Ding Nonresolving inflammation Cell 140 2010 871 882
-
(2010)
Cell
, vol.140
, pp. 871-882
-
-
Nathan, C.1
Ding, A.2
-
20
-
-
47949099098
-
Origin and physiological roles of inflammation
-
R. Medzhitov Origin and physiological roles of inflammation Nature 454 2008 428 435
-
(2008)
Nature
, vol.454
, pp. 428-435
-
-
Medzhitov, R.1
-
21
-
-
50249116184
-
The endoplasmic reticulum stress response in immunity and autoimmunity
-
D.J. Todd, A.H. Lee, and L.H. Glimcher The endoplasmic reticulum stress response in immunity and autoimmunity Nat Rev Immunol 8 2008 663 674
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 663-674
-
-
Todd, D.J.1
Lee, A.H.2
Glimcher, L.H.3
-
22
-
-
75649093343
-
Toll-like receptor signalling in the intestinal epithelium: How bacterial recognition shapes intestinal function [published erratum in: Nat Rev Immunol 2010;10:215]
-
M.T. Abreu Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function [published erratum in: Nat Rev Immunol 2010;10:215] Nat Rev Immunol 10 2010 131 144
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 131-144
-
-
Abreu, M.T.1
-
23
-
-
70350513270
-
Regulation of tissue homeostasis by NF-kappaB signalling: Implications for inflammatory diseases
-
M. Pasparakis Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases Nat Rev Immunol 9 2009 778 788
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 778-788
-
-
Pasparakis, M.1
-
24
-
-
34047173496
-
Epithelial NEMO links innate immunity to chronic intestinal inflammation
-
DOI 10.1038/nature05698, PII NATURE05698
-
A. Nenci, C. Becker, A. Wullaert, R. Gareus, G. van Loo, and S. Danese Epithelial NEMO links innate immunity to chronic intestinal inflammation Nature 446 2007 557 561 (Pubitemid 46514732)
-
(2007)
Nature
, vol.446
, Issue.7135
, pp. 557-561
-
-
Nenci, A.1
Becker, C.2
Wullaert, A.3
Gareus, R.4
Van Loo, G.5
Danese, S.6
Huth, M.7
Nikolaev, A.8
Neufert, C.9
Madison, B.10
Gumucio, D.11
Neurath, M.F.12
Pasparakis, M.13
-
25
-
-
27144520307
-
Mechanisms of disease: Defensins in gastrointestinal diseases
-
DOI 10.1038/ncpgasthep0265, PII N0265
-
J. Wehkamp, K. Fellermann, K.R. Herrlinger, C.L. Bevins, and E.F. Stange Mechanisms of disease: defensins in gastrointestinal diseases Nat Clin Pract Gastroenterol Hepatol 2 2005 406 415 (Pubitemid 41486093)
-
(2005)
Nature Clinical Practice Gastroenterology and Hepatology
, vol.2
, Issue.9
, pp. 406-415
-
-
Wehkamp, J.1
Fellermann, K.2
Herrlinger, K.R.3
Bevins, C.L.4
Stange, E.F.5
-
26
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
K. Cadwell, J.Y. Liu, S.L. Brown, H. Miyoshi, J. Loh, and J.K. Lennerz A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells Nature 456 2008 259 263
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
Miyoshi, H.4
Loh, J.5
Lennerz, J.K.6
-
27
-
-
77953904042
-
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
-
K. Cadwell, K.K. Patel, N.S. Maloney, T.C. Liu, A.C. Ng, and C.E. Storer Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine Cell 141 2010 1135 1145
-
(2010)
Cell
, vol.141
, pp. 1135-1145
-
-
Cadwell, K.1
Patel, K.K.2
Maloney, N.S.3
Liu, T.C.4
Ng, A.C.5
Storer, C.E.6
-
28
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
A. Kaser, A.H. Lee, A. Franke, J.N. Glickman, S. Zeissig, and H. Tilg XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease Cell 134 2008 743 756
-
(2008)
Cell
, vol.134
, pp. 743-756
-
-
Kaser, A.1
Lee, A.H.2
Franke, A.3
Glickman, J.N.4
Zeissig, S.5
Tilg, H.6
-
29
-
-
77950353786
-
Homeostasis and inflammation in the intestine
-
W.S. Garrett, J.I. Gordon, and L.H. Glimcher Homeostasis and inflammation in the intestine Cell 140 2010 859 870
-
(2010)
Cell
, vol.140
, pp. 859-870
-
-
Garrett, W.S.1
Gordon, J.I.2
Glimcher, L.H.3
-
30
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
L.H. Travassos, L.A. Carneiro, M. Ramjeet, S. Hussey, Y.G. Kim, and J.G. Magalhães Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry Nat Immunol 11 2010 55 62
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
Hussey, S.4
Kim, Y.G.5
Magalhães, J.G.6
-
33
-
-
77954943215
-
Epithelial decision makers: In search of the "epimmunome
-
M. Swamy, C. Jamora, W. Havran, and A. Hayday Epithelial decision makers: in search of the "epimmunome." Nat Immunol 11 2010 656 665
-
(2010)
Nat Immunol
, vol.11
, pp. 656-665
-
-
Swamy, M.1
Jamora, C.2
Havran, W.3
Hayday, A.4
-
34
-
-
79959201412
-
Human nutrition, the gut microbiome and the immune system
-
A.L. Kau, P.P. Ahern, N.W. Griffin, A.L. Goodman, and J.I. Gordon Human nutrition, the gut microbiome and the immune system Nature 474 2011 327 336
-
(2011)
Nature
, vol.474
, pp. 327-336
-
-
Kau, A.L.1
Ahern, P.P.2
Griffin, N.W.3
Goodman, A.L.4
Gordon, J.I.5
-
35
-
-
79952748287
-
Unravelling the effects of the environment and host genotype on the gut microbiome
-
A. Spor, O. Koren, and R. Ley Unravelling the effects of the environment and host genotype on the gut microbiome Nat Rev Microbiol 9 2011 279 290
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 279-290
-
-
Spor, A.1
Koren, O.2
Ley, R.3
-
36
-
-
77953482525
-
Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF kappaB inactivation
-
L.E. Smythies, R. Shen, D. Bimczok, L. Novak, R.H. Clements, and D.E. Eckhoff Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF kappaB inactivation J Biol Chem 285 2010 19593 19604
-
(2010)
J Biol Chem
, vol.285
, pp. 19593-19604
-
-
Smythies, L.E.1
Shen, R.2
Bimczok, D.3
Novak, L.4
Clements, R.H.5
Eckhoff, D.E.6
-
38
-
-
56349139080
-
Interactions among dendritic cells, macrophages, and epithelial cells in the gut: Implications for immune tolerance
-
M. Rescigno, U. Lopatin, and M. Chieppa Interactions among dendritic cells, macrophages, and epithelial cells in the gut: implications for immune tolerance Curr Opin Immunol 20 2008 669 675
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 669-675
-
-
Rescigno, M.1
Lopatin, U.2
Chieppa, M.3
-
39
-
-
78049253032
-
The hygiene hypothesis revisited: Role of materno-fetal interactions
-
C.A. Thornton, T.V. Macfarlane, and P.G. Holt The hygiene hypothesis revisited: role of materno-fetal interactions Curr Allergy Asthma Rep 10 2010 444 452
-
(2010)
Curr Allergy Asthma Rep
, vol.10
, pp. 444-452
-
-
Thornton, C.A.1
MacFarlane, T.V.2
Holt, P.G.3
-
42
-
-
77958469091
-
Update on mucosal immunoglobulin A in gastrointestinal disease
-
P. Brandtzaeg Update on mucosal immunoglobulin A in gastrointestinal disease Curr Opin Gastroenterol 26 2010 554 563
-
(2010)
Curr Opin Gastroenterol
, vol.26
, pp. 554-563
-
-
Brandtzaeg, P.1
-
43
-
-
78649893491
-
Prevention measures and exploratory pharmacological treatments of celiac disease [published erratum in: Am J Gastroenterol 2011;106:375]
-
M. Pinier, G. Fuhrmann, E.F. Verdu, and J.C. Leroux Prevention measures and exploratory pharmacological treatments of celiac disease [published erratum in: Am J Gastroenterol 2011;106:375] Am J Gastroenterol 105 2010 2551 2562
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 2551-2562
-
-
Pinier, M.1
Fuhrmann, G.2
Verdu, E.F.3
Leroux, J.C.4
-
44
-
-
79551694651
-
The microbiome-gut-brain axis: From bowel to behavior
-
J.F. Cryan, and S.M. O'Mahony The microbiome-gut-brain axis: from bowel to behavior Neurogastroenterol Motil 23 2011 187 192
-
(2011)
Neurogastroenterol Motil
, vol.23
, pp. 187-192
-
-
Cryan, J.F.1
O'Mahony, S.M.2
-
46
-
-
0037136537
-
The effect of infections on susceptibility to autoimmune and allergic diseases
-
J.F. Bach The effect of infections on susceptibility to autoimmune and allergic diseases N Engl J Med 347 2002 911 920
-
(2002)
N Engl J Med
, vol.347
, pp. 911-920
-
-
Bach, J.F.1
-
48
-
-
79959201412
-
Human nutrition, the gut microbiome and the immune system
-
A.L. Kau, P.P. Ahern, N.W. Griffin, A.L. Goodman, and J.I. Gordon Human nutrition, the gut microbiome and the immune system Nature 474 2011 327 336
-
(2011)
Nature
, vol.474
, pp. 327-336
-
-
Kau, A.L.1
Ahern, P.P.2
Griffin, N.W.3
Goodman, A.L.4
Gordon, J.I.5
-
49
-
-
77950251400
-
A human gut microbial gene catalogue established by metagenomic sequencing
-
J. Qin, R. Li, J. Raes, M. Arumugam, K.S. Burgdorf, and C. Manichanh A human gut microbial gene catalogue established by metagenomic sequencing Nature 464 2010 59 65
-
(2010)
Nature
, vol.464
, pp. 59-65
-
-
Qin, J.1
Li, R.2
Raes, J.3
Arumugam, M.4
Burgdorf, K.S.5
Manichanh, C.6
-
50
-
-
79955935457
-
Intestinal microbiota in inflammatory bowel disease: Friend of foe?
-
F. Fava, and S. Danese Intestinal microbiota in inflammatory bowel disease: friend of foe? World J Gastroenterol 17 2011 557 566
-
(2011)
World J Gastroenterol
, vol.17
, pp. 557-566
-
-
Fava, F.1
Danese, S.2
-
51
-
-
72949091232
-
Bacterial community variation in human body habitats across space and time
-
E.K. Costello, C.L. Lauber, M. Hamady, N. Fierer, J.I. Gordon, and R. Knight Bacterial community variation in human body habitats across space and time Science 326 2009 1694 1697
-
(2009)
Science
, vol.326
, pp. 1694-1697
-
-
Costello, E.K.1
Lauber, C.L.2
Hamady, M.3
Fierer, N.4
Gordon, J.I.5
Knight, R.6
-
52
-
-
77649119443
-
Disordered microbial communities in asthmatic airways
-
M. Hilty, C. Burke, H. Pedro, P. Cardenas, A. Bush, and C. Bossley Disordered microbial communities in asthmatic airways PLoS One 5 2010 e8578
-
(2010)
PLoS One
, vol.5
, pp. 8578
-
-
Hilty, M.1
Burke, C.2
Pedro, H.3
Cardenas, P.4
Bush, A.5
Bossley, C.6
-
53
-
-
77955386857
-
Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
-
M.G. Dominguez-Bello, E.K. Costello, M. Contreras, M. Magris, G. Hidalgo, and N. Fierer Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns Proc Natl Acad Sci U S A 107 2010 11971 11974
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 11971-11974
-
-
Dominguez-Bello, M.G.1
Costello, E.K.2
Contreras, M.3
Magris, M.4
Hidalgo, G.5
Fierer, N.6
-
54
-
-
56649089777
-
Is caesarean delivery associated with sensitization to food allergens and IgE-mediated food allergy: A systematic review
-
J. Koplin, K. Allen, L. Gurrin, N. Osborne, M.L. Tang, and S. Dharmage Is caesarean delivery associated with sensitization to food allergens and IgE-mediated food allergy: a systematic review Pediatr Allergy Immunol 19 2008 682 687
-
(2008)
Pediatr Allergy Immunol
, vol.19
, pp. 682-687
-
-
Koplin, J.1
Allen, K.2
Gurrin, L.3
Osborne, N.4
Tang, M.L.5
Dharmage, S.6
-
55
-
-
38649115342
-
Microbial Influences in Inflammatory Bowel Diseases
-
DOI 10.1053/j.gastro.2007.11.059, PII S0016508507021579
-
R.B. Sartor Microbial influences in inflammatory bowel diseases Gastroenterology 134 2008 577 594 (Pubitemid 351173057)
-
(2008)
Gastroenterology
, vol.134
, Issue.2
, pp. 577-594
-
-
Sartor, R.B.1
-
56
-
-
78649512314
-
Farm living: Effects on childhood asthma and allergy
-
E. von Mutius, and D. Vercelli Farm living: effects on childhood asthma and allergy Nat Rev Immunol 10 2010 861 868
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 861-868
-
-
Von Mutius, E.1
Vercelli, D.2
-
57
-
-
79951972586
-
Exposure to environmental microorganisms and childhood asthma
-
M.J. Ege, M. Mayer, A.C. Normand, J. Genuneit, W.O. Cookson, and C. Braun-Fahrlander Exposure to environmental microorganisms and childhood asthma N Engl J Med 364 2011 701 709
-
(2011)
N Engl J Med
, vol.364
, pp. 701-709
-
-
Ege, M.J.1
Mayer, M.2
Normand, A.C.3
Genuneit, J.4
Cookson, W.O.5
Braun-Fahrlander, C.6
-
58
-
-
35248851540
-
Childhood asthma after bacterial colonization of the airway in neonates
-
DOI 10.1056/NEJMoa052632
-
H. Bisgaard, M.N. Hermansen, F. Buchvald, L. Loland, L.B. Halkjaer, and K. Bonnelykke Childhood asthma after bacterial colonization of the airway in neonates N Engl J Med 357 2007 1487 1495 (Pubitemid 47572634)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.15
, pp. 1487-1495
-
-
Bisgaard, H.1
Hermansen, M.N.2
Buchvald, F.3
Loland, L.4
Halkjaer, L.B.5
Bonnelykke, K.6
Brasholt, M.7
Heltberg, A.8
Vissing, N.H.9
Thorsen, S.V.10
Stage, M.11
Pipper, C.B.12
-
59
-
-
77949355221
-
99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Immune therapies of type 1 diabetes: New opportunities based on the hygiene hypothesis
-
L. Chatenoud, S. You, H. Okada, C. Kuhn, B. Michaud, and J.F. Bach 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: immune therapies of type 1 diabetes: new opportunities based on the hygiene hypothesis Clin Exp Immunol 160 2010 106 112
-
(2010)
Clin Exp Immunol
, vol.160
, pp. 106-112
-
-
Chatenoud, L.1
You, S.2
Okada, H.3
Kuhn, C.4
Michaud, B.5
Bach, J.F.6
-
60
-
-
68149091349
-
Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism
-
E. Slack, S. Hapfelmeier, B. Stecher, Y. Velykoredko, M. Stoel, and M.A. Lawson Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism Science 325 2009 617 620
-
(2009)
Science
, vol.325
, pp. 617-620
-
-
Slack, E.1
Hapfelmeier, S.2
Stecher, B.3
Velykoredko, Y.4
Stoel, M.5
Lawson, M.A.6
-
61
-
-
77950857047
-
Emerging biologics in the treatment of inflammatory bowel disease: What is around the corner?
-
G. Fiorino, S. Rovida, C. Correale, A. Malesci, and S. Danese Emerging biologics in the treatment of inflammatory bowel disease: what is around the corner? Curr Drug Targets 11 2010 249 260
-
(2010)
Curr Drug Targets
, vol.11
, pp. 249-260
-
-
Fiorino, G.1
Rovida, S.2
Correale, C.3
Malesci, A.4
Danese, S.5
-
62
-
-
79955552936
-
Interactions between the host innate immune system and microbes in inflammatory bowel disease
-
C. Abraham, and R. Medzhitov Interactions between the host innate immune system and microbes in inflammatory bowel disease Gastroenterology 140 2011 1729 1737
-
(2011)
Gastroenterology
, vol.140
, pp. 1729-1737
-
-
Abraham, C.1
Medzhitov, R.2
-
63
-
-
77953039047
-
A randomized, controlled, phase 2 study of AMG 317, an IL-4 Ralpha antagonist, in patients with asthma
-
J. Corren, W. Busse, E.O. Meltzer, L. Mansfield, G. Bensch, and J. Fahrenholz A randomized, controlled, phase 2 study of AMG 317, an IL-4 Ralpha antagonist, in patients with asthma Am J Respir Crit Care Med 181 2010 788 796
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 788-796
-
-
Corren, J.1
Busse, W.2
Meltzer, E.O.3
Mansfield, L.4
Bensch, G.5
Fahrenholz, J.6
-
64
-
-
77951672627
-
Accumulation of intraepithelial mast cells with a unique protease phenotype in TH2-high asthma
-
e8
-
R.H. Dougherty, S.S. Sidhu, K. Raman, M. Solon, O.D. Solberg, and G.H. Caughey Accumulation of intraepithelial mast cells with a unique protease phenotype in TH2-high asthma J Allergy Clin Immunol 125 2010 1046 1053 e8
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 1046-1053
-
-
Dougherty, R.H.1
Sidhu, S.S.2
Raman, K.3
Solon, M.4
Solberg, O.D.5
Caughey, G.H.6
-
65
-
-
69249150516
-
T-helper type 2-driven inflammation defines major subphenotypes of asthma
-
P.G. Woodruff, B. Modrek, D.F. Choy, G. Jia, A.R. Abbas, and A. Ellwanger T-helper type 2-driven inflammation defines major subphenotypes of asthma Am J Respir Crit Care Med 180 2009 388 395
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 388-395
-
-
Woodruff, P.G.1
Modrek, B.2
Choy, D.F.3
Jia, G.4
Abbas, A.R.5
Ellwanger, A.6
-
66
-
-
80053084755
-
Lebrikizumab treatment in adults with asthma
-
[Epub ahead of print]
-
J. Corren, R.F. Lemanske, N.A. Hanania, P.E. Korenblat, M.V. Parsey, and J.R. Arron Lebrikizumab treatment in adults with asthma N Engl J Med 2011 [Epub ahead of print]
-
(2011)
N Engl J Med
-
-
Corren, J.1
Lemanske, R.F.2
Hanania, N.A.3
Korenblat, P.E.4
Parsey, M.V.5
Arron, J.R.6
-
67
-
-
55049138055
-
Inhaled sodium cromoglycate for asthma in children
-
J.C. van der Wouden, J.H. Uijen, R.M. Bernsen, M.J. Tasche, J.C. de Jongste, and F. Durcharme Inhaled sodium cromoglycate for asthma in children Cochrane Database Syst Rev 4 2008 CD002173
-
(2008)
Cochrane Database Syst Rev
, Issue.4
, pp. 002173
-
-
Van Der Wouden, J.C.1
Uijen, J.H.2
Bernsen, R.M.3
Tasche, M.J.4
De Jongste, J.C.5
Durcharme, F.6
-
68
-
-
77950271175
-
A review of treatment with mepolizumab, an anti-IL-5 mAb, in hypereosinophilic syndromes and asthma
-
W.W. Busse, J. Rin, J. Huss-Marp, and J.E. Kahn A review of treatment with mepolizumab, an anti-IL-5 mAb, in hypereosinophilic syndromes and asthma J Allergy Clin Immunol 125 2010 803 813
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 803-813
-
-
Busse, W.W.1
Rin, J.2
Huss-Marp, J.3
Kahn, J.E.4
-
69
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
P. Nair, M. Pizzichini, M. Kjarsgaard, M.D. Inman, A. Efthimiadis, and M. Pizz Mepolizumab for prednisone-dependent asthma with sputum eosinophilia N Engl J Med 360 2009 985 993
-
(2009)
N Engl J Med
, vol.360
, pp. 985-993
-
-
Nair, P.1
Pizzichini, M.2
Kjarsgaard, M.3
Inman, M.D.4
Efthimiadis, A.5
Pizz, M.6
-
70
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
P. Haldar, C.E. Brightling, B. Hargadon, S. Gupta, M. Monteiro, and M. Sousa Mepolizumab and exacerbations of refractory eosinophilic asthma N Engl J Med 360 2009 973 984
-
(2009)
N Engl J Med
, vol.360
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
Gupta, S.4
Monteiro, M.5
Sousa, M.6
-
73
-
-
77953359952
-
AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis
-
S. Caluwaerts, K. Vandenbroucke, L. Steidler, S. Neirynchk, P. Vanhoenacker, and S. Corveleyn AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis Oral Oncol 46 2010 564 570
-
(2010)
Oral Oncol
, vol.46
, pp. 564-570
-
-
Caluwaerts, S.1
Vandenbroucke, K.2
Steidler, L.3
Neirynchk, S.4
Vanhoenacker, P.5
Corveleyn, S.6
-
74
-
-
33749022511
-
Therapeutic drug delivery by genetically modified Lactococcus lactis
-
DOI 10.1196/annals.1326.031, Inflammatory Bowel Disease: Genetics, Barrier Function, Immunologic Mechanisms, and Microbial Pathways
-
L. Steidler, and P. Rottiers Therapeutic drug delivery by genetically modified Lactococcus lactis Ann N Y Acad Sci 1072 2006 176 186 (Pubitemid 44448451)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1072
, pp. 176-186
-
-
Steidler, L.1
Rottiers, P.2
-
75
-
-
72449193576
-
Practical prebiotics, probiotics and synbiotics for allergists: How useful are they?
-
H. Johannsen, and S.L. Prescott Practical prebiotics, probiotics and synbiotics for allergists: how useful are they? Clin Exp Allergy 39 2009 1801 1814
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 1801-1814
-
-
Johannsen, H.1
Prescott, S.L.2
-
76
-
-
66849138606
-
Lower protein in infant formula is associated with lower weight up to age 2 y: A randomized clinical trial
-
B. Koletzko, R. von Kries, R. Closa, J. Escribano, S. Scaglioni, and M. Giovannini Lower protein in infant formula is associated with lower weight up to age 2 y: a randomized clinical trial Am J Clin Nutr 89 2009 1836 1845
-
(2009)
Am J Clin Nutr
, vol.89
, pp. 1836-1845
-
-
Koletzko, B.1
Von Kries, R.2
Closa, R.3
Escribano, J.4
Scaglioni, S.5
Giovannini, M.6
-
77
-
-
55849150592
-
In utero supplementation with methyl donors enhances allergic airway disease in mice
-
J.W. Hollingsworth, S. Maruka, K. Boon, S. Garantziotis, Z. Li, and J. Tomfohr In utero supplementation with methyl donors enhances allergic airway disease in mice J Clin Invest 118 2008 3462 3469
-
(2008)
J Clin Invest
, vol.118
, pp. 3462-3469
-
-
Hollingsworth, J.W.1
Maruka, S.2
Boon, K.3
Garantziotis, S.4
Li, Z.5
Tomfohr, J.6
-
78
-
-
2342660790
-
Functional food science and gastrointestinal physiology and function
-
S. Salminen, C. Bouley, M.C. Boutron-Ruault, J.H. Cummings, A. Franck, and G.R. Gibson Functional food science and gastrointestinal physiology and function Br J Nutr 80 suppl 1 1998 S147 S171
-
(1998)
Br J Nutr
, vol.80
, Issue.SUPPL. 1
-
-
Salminen, S.1
Bouley, C.2
Boutron-Ruault, M.C.3
Cummings, J.H.4
Franck, A.5
Gibson, G.R.6
-
79
-
-
77955810123
-
Food allergy: Separating the science from the mythology
-
P. Brandtzaeg Food allergy: separating the science from the mythology Nat Rev Gastroenterol Hepatol 7 2010 380 400
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 380-400
-
-
Brandtzaeg, P.1
-
80
-
-
79951613680
-
Specific oral tolerance induction in food allergic children: Is oral desensitisation more effective than allergen avoidance?: A meta-analysis of published RCTs
-
H.R. Fisher, G. Du Toit, and G. Lack Specific oral tolerance induction in food allergic children: is oral desensitisation more effective than allergen avoidance?: a meta-analysis of published RCTs Arch Dis Child 96 2011 259 264
-
(2011)
Arch Dis Child
, vol.96
, pp. 259-264
-
-
Fisher, H.R.1
Du Toit, G.2
Lack, G.3
-
81
-
-
79952929840
-
Gene-environment interactions in chronic inflammatory disease
-
H. Renz, E. von Mutius, P. Brandtzaeg, W.O. Cookson, I.B. Autenrieth, and D. Haller Gene-environment interactions in chronic inflammatory disease Nat Immunol 12 2011 273 277
-
(2011)
Nat Immunol
, vol.12
, pp. 273-277
-
-
Renz, H.1
Von Mutius, E.2
Brandtzaeg, P.3
Cookson, W.O.4
Autenrieth, I.B.5
Haller, D.6
|