Fibronectin protects from excessive liver fibrosis by modulating the availability of and responsiveness of stellate cells to active TGF-β

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Kawelke, Nina ^a,b   Vasel, Matthaeus ^a,b   Sens, Carla ^a,b   von Au, Anja ^a,b   Dooley, Steven ^b   Nakchbandi, Inaam A ^a,b  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; DIMETHYLNITROSAMINE; FIBRONECTIN; INTEGRIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; GENE DELETION; IN VITRO STUDY; LIVER CELL; LIVER FIBROSIS; LIVER PROTECTION; MOUSE; NONHUMAN; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STELLATE CELL;

ANIMALS; APOPTOSIS; COLLAGEN; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; FIBRONECTINS; GENE DELETION; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; HEPATIC STELLATE CELLS; HEPATOCYTES; KUPFFER CELLS; LIVER CIRRHOSIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 82155188913     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028181     Document Type: Article

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