Modulation of cell-adhesive activity of fibronectin by the alternatively spliced EDA segment

Journal of Cell Biology

Volumn 139, Issue 1, 1997, Pages 295-307

  Manabe, Ri Ichiroh ^a   Oh E, Naoko ^a   Maeda, Toshinaga ^a   Fukuda, Tomohiko ^a   Sekiguchi, Kiyotoshi ^a  

^a RESEARCH INSTITUTE FOR MATERNAL AND CHILD HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; INTEGRIN; MESSENGER RNA;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CELL SPREADING; CHO CELL; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; RAT;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL ADHESION; CELL MEMBRANE; CELL MOVEMENT; CHO CELLS; CRICETINAE; FIBROBLASTS; FIBRONECTINS; FIBROSARCOMA; GENETIC VECTORS; HEPARITIN SULFATE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RATS; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED;

EID: 0030753274     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.139.1.295     Document Type: Article

References (69)

1. Aguirre, K.M., R.J. McCormick, and J.E. Schwarzbauer. 1994. Fibronectin self-association is mediated by complementary sites within the amino-terminal one-third of the molecule. J. Biol. Chem. 269:27863-27868.
2. Akamatsu, H., K. Ichihara-Tanaka, K. Ozono, W. Kamiike, H. Matsuda, and K. Sekiguchi. 1996. Suppression of transformed phenotypes of human fibrosarcoma cells by overexpression of recombinant fibronectin. Cancer Res. 56: 4541-4546.
3. Akiyama, S.K., E. Hasegawa, T. Hasegawa, and K.M. Yamada. 1985. The interaction of fibronectin fragments with fibroblastic cells. J. Biol. Chem. 260: 13256-13260.
4. Aota, S., T. Nagai, and K.M. Yamada. 1991. Characterization of regions of fibronectin besides the arginine-glycine-aspartic acid sequence required for adhesive function of the cell-binding domain using site-directed mutagenesis. J. Biol. Chem. 266:15938-15943.
5. Aota, S., M. Nomizu, and K.M. Yamada. 1994. The short amino acid sequence Pro-His-Ser-Arg-Asn in human fibronectin enhances cell-adhesive function J. Biol. Chem. 269:24756-24761.
6. Benecky, M.J., C.G. Kolvenbach, R.W. Wine, J.P. DiOrio, and M.W. Mosesson. 1990. Human plasma fibronectin structure probed by steady-state fluorescence polarization: evidence for a rigid oblate structure. Biochemistry. 29: 3082-3091.
7. Borsi, L., B. Carnemolla, P. Catellani, C. Rosellini, D. Vecchio, G. Allemanni, S.E. Chang, J. Taylor-Papadimitriou, H. Pande, and L. Zardi. 1987. Monoclonal antibodies in the analysis of fibronectin isoforms generated by alternative splicing of mRNA precursors in normal and transformed cells. J. Cell Biol. 104:595-600.
8. Bowditch, R.D., M. Hariharan, E.F. Tominna, J.W. Smith, K.M. Yamada, E.D. Getzoff, and M.H. Ginsberg. 1994. Identification of a novel binding site in fibronectin: differential utilization by β3 integrins. J. Biol. Chem. 269:10856-10863.
9. Carnemolla, B., E. Balza, A. Siri, L. Zardi, M.R. Nicotra. A. Bigotti, and P.G. Natali. 1989. A tumor-associated fibronectin isoform generated by alternative splicing of messenger RNA precursors. J. Cell Biol. 108:1139-1148.
10. Chen, C., and H. Okayama. 1987. High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7:2745-2752.
11. Chen, J., T. Maeda, K. Sekiguchi, and D. Sheppard. 1996. Distinct structural requirements for interaction of the integrins α5β1, αvβ5, and αvβ6 with the central cell binding domain in fibronectin. Cell Adhes. Commun. 4:237-250.
12. Danen, E.H.J., S. Aota, A.A. van Kraats, K.M. Yamada, D.J. Ruiter, and G.N.P. van Muijen. 1995. Requirement for the synergy site for cell adhesion to fibronectin depends on the activation state of integrin α5β1. J. Biol. Chem. 270:21612-21618.
13. Erickson, H.P. 1994. Reversible unfolding of fibronectin type III and immunoglobulin domains provides the structural basis for stretch and elasticity of titin and fibronectin. Proc. Natl. Acad. Sci. USA. 91:10114-10118.
14. Erickson, H.P., and N.A. Carrell. 1983. Fibronectin in extended and compact conformations: electron microscopy and sedimentation analysis. J. Biol. Chem. 258:14539-14544.
15. Esko, J.D., K.S. Rostand, J.L. Weinke. 1988. Tumor formation dependent on proteoglycan biosynthesis. Science (Wash. DC). 241:1092-1096.
16. ffrench-Constant, C. 1995. Alternative splicing of fibronectin: many different proteins but few different functions. Exp. Cell Res. 221:261-271.
17. ffrench-Constant, C., and R.O. Hynes. 1989. Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo. Development. 106:375-388.
18. ffrench-Constant, C., L. Van De Water, H.F. Dvorak, and R.O. Hynes. 1989. Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat. J. Cell Biol. 109:903-914.
19. Fukuda, M., S.B. Levery, and S. Hakomori. 1982. Carbohydrate structure of hamster plasma fibronectin: evidence for chemical diversity between cellular and plasma fibronectins. J. Biol. Chem. 257:6856-6860.
20. George, E.L., E.N. Georges-Labouesse, R.S. Patel-King, H. Rayburn, and R.O. Hynes. 1993. Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development. 119:1079-1091.
21. Giancotti, F.G., and E. Ruoslahti. 1990. Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells. Cell. 60:849-859.
22. Guan, J.-L., J.E. Trevithick, and R.O. Hynes. 1990. Retroviral expression of alternatively spliced forms of rat fibronectin. J. Cell Biol. 110:833-847.
23. Hayashi, M., and K.M. Yamada. 1983. Domain structure of the carboxyl-terminal half of human plasma fibronectin. J. Biol. Chem. 258:3332-3340.
24. Hino, K., T. Maeda, K. Sekiguchi, K. Shiozawa, H. Hirano, E. Sakashita, and S. Shiozawa. 1996. Adherence of synovial cells on EDA-containing fibronectin. Arthritis Rheum. 39:1685-1692.
25. Hirano, H., T. Tachikawa, K. Hino, E. Sakashita, and K. Sekiguchi. 1992. Development of enzyme-linked immunosorbent assasy (ELISA) for the detection of cellular type fibronectin by EDA-region specific monoclonal antibody. J. Clin. Lab. Inst. Reag. 15:179-184.
26. Hocking, D.C., R.K. Smith, and P.J. McKeown-Longo. 1996. A novel role for the integrin-binding III-10 module in fibronectin matrix assembly. J. Cell Biol. 133:431-444.
27. Huber, A.H., Y.E. Wang, A.J. Bieber, and P.J. Bjorkman. 1994. Crystal structure of tandem type III fibronectin domains from Drosophila neuroglian at 2.0 Å. Neuron. 12:717-731.
28. Hynes, R.O. 1990. Fibronectins. Springer-Verlag, New York. 546 pp.
29. Hynes, R.O. 1992. Integrins: versatility, modulation, and signaling in cell adhesion. Cell. 69:11-25.
30. Ichihara-Tanaka, K., K. Titani, and K. Sekiguchi. 1990. Recombinant carboxyl-terminal fibrin-binding domain of human fibronectin expressed in mouse L cells. J. Biol. Chem. 265:401-107.
31. Ingham, K.C., S.A. Brew, S. Huff, and S.V. Litvinovich. 1997. Cryptic self-association sites in type HI modules of fibronectin. J. Biol. Chem. 272:1718-1724.
32. Jarnagin, W.R., D.C. Rockey, V.E. Koteliansky, S. Wang, and D.M. Bissell. 1994. Expression of variant fibronectins in wound healing: cellular source and biological activity of the EIIIA segment in rat hepatic fibrogenesis. J. Cell Biol. 127:2037-2048.
33. Kaufman, R.J. 1989. Selection and coamplification. Methods Enzymol. 185: 537-566,
34. Kornblihtt, A.R., K. Vibe-Pedersen, and F.E. Baralle. 1984. Human fibronectin: cell specific alternative mRNA splicing generates polypeptide chains differing in the number of internal repeats. Nucleic Acids Res. 12:5853-5868.
35. Kornblihtt, A.R., K. Umezawa, K. Vibe-Pedersen, and F.E. Baralle. 1985. Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene. EMBO (Eur. Mol. Biol. Organ.) J. 4:1755-1759.
36. Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature (Lond.). 227:680-685.
37. Leahy, D.J., I. Aukhil, and H.P. Erickson. 1996. 2.0 Å crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region. Cell. 84:155-164.
38. Magnuson, V.L., M. Young, D.G. Schattenberg, M.A. Maricini, D. Chen, B. Steffensen, and R.J. Klebe. 1991. The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors. J. Biol. Chem. 266:14654-14662.
39. Matsuyama, S., K. Ichihara-Tanaka, and K. Sekiguchi. 1994. Targeting of the immunoglobulin-binding domain of protein A to the extracellular matrix using a minifibronectin expression vector. J. Biochem. 116:898-904.
40. Meredith, J.E., Jr., B. Fazeli, and M.A. Schwartz. 1993. The extracellular matrix as a cell survival factor. Mol. Biol. Cell. 4:953-961.
41. Miyake, K., Y. Hasunuma, H. Yagita, and M. Kimoto. 1992. Requirement for VLA-4 and VLA-5 integrins in lymphoma cells binding to and migration beneath stromal cells in culture. J. Cell Biol. 119:653-662.
42. Mosher, D.F. 1993. Assembly of fibronectin into extracellular matrix. Curr. Opin. Struct. Biol. 3:214-222.
43. Müller, U., B. Bossy, K. Venstrom, and L.F. Reichardt. 1995. Integrin α8β1 promotes attachment, cell spreading and neurite outgrowth on fibronectin. Mol. Biol. Cell. 6:433-448.
44. Oyama, F., S. Hirohashi, Y. Shimosato, K. Titani, and K. Sekiguchi. 1989a. Deregulation of alternative splicing of fibronectin pre-mRNA in malignant human liver tumors. J. Biol. Chem. 264:10331-10334.
45. Oyama, F., Y. Murata, N. Suganuma, T. Kimura, K. Titani, and K. Sekiguchi. 1989b. Patterns of alternative splicing of fibronectin pre-mRNA in human adult and fetal tissues. Biochemistry. 28:1428-1434.
46. Oyama, F., S. Hirohashi, M. Sakamoto, K. Titani, and K. Sekiguchi. 1993. Coordinate oncodevelopmental modulation of alternative splicing of fibronectin pre-messenger RNA at ED-A, ED-B, and CS1 regions in human liver tumors. Cancer Res. 53:2005-2011.
47. Paul, J.I., and R.O. Hynes. 1984. Multiple fibronectin subunits and their post-translational modifications. J. Biol. Chem. 259:13477-13487.
48. Petersen, T.E., H.C. Thøgersen, K. Skorstengaard, K. Vibe-Pedersen, P. Sahl, L. Sottrup-Jenesen, and S. Magnusson. 1983. Partial primary structure of bovine plasma fibronectin: three types of internal homology. Proc. Natl. Acad. Sci. USA. 80:137-141.
49. Petersen, T.F., K. Skorstengaard, and K. Vibe-Pedersen. 1989. Primary structure of fibronectin. In Fibronectin. D.F. Mosher, editor. Academic Press, San Diego, CA. 1-24.
50. Pytela, R., M.D. Pierschbacher, S. Argraves, S. Suzuki, and E. Ruoslahti. 1987. Arginine-glycine-aspartic acid adhesion receptors. Methods Enzymol. 144: 475-489.
51. Ruoslahli, E., and M.D. Pierschbacher. 1987. New perspectives in cell adhesion: RGD and integrins. Science (Wash. DC). 238:491-497.
52. Schwarzbauer, J.E., J.W. Tamkun, I.R. Lemischka, and R.O. Hynes. 1983. Three different fibronectin mRNA arise by alternative splicing within the coding region. Cell. 35:421-431.
53. Schwarzbauer, J.E., R.S. Patel, D. Fonda, and R.O. Hynes. 1987. Multiple sites of alternative splicing of the rat fibronectin gene transcript. EMBO (Eur. Mol. Biol. Organ.) J. 6:2573-2580.
54. Schwarzbauer, J.E., C.S. Spencer, and C.L. Wilson. 1989. Selective secretion of alternatively spliced fibronectin variants. J. Cell Biol. 109:3445-3453.
55. Sechler, J.L., Y. Takada, and J.E. Schwarzbauer. 1996. Altered rate of fibronectin matrix assembly by deletion of the first type III repeats. J. Cell Biol. 134: 573-583.
56. Sekiguchi, K., and K. Titani. 1989. Probing molecular polymorphism of fibronectins with antibodies directed to the alternatively spliced peptide segments. Biochemistry. 28:3293-3298.
57. Sekiguchi, K., A. Siri, L. Zardi, and S. Hakomori. 1985. Differences in domain structure between human fibronectins isolated from plasma and from culture supernatants of normal and transformed fibroblasts: studies with domain-specific antibodies. J. Biol. Chem. 260:5105-5114.
58. Sekiguchi, K., A.M. Klos, K. Kurachi, S. Yoshitake, and S. Hakomori. 1986. Human liver fibronectin complementary DNAs: identification of two different messenger RNAs possibly encoding the α and β subunits of plasma fibronectin. Biochemistry. 25:4936-4941.
59. Vartio, T., L. Laitinen, O. Närvänen, M. Cutolo, L.-E. Thornell, L. Zardi, and I. Virtanen. 1987. Differential expression of the ED sequence-containing form of cellular fibronectin in embryonic and adult human tissues. J. Cell Sci. 88: 419-430.
60. Williams, E.C., P.A. Janmey, J.D. Ferry, and D.F. Mosher. 1982. Conformational states of fibronectin: effects of pH , ionic strength, and collagen binding. J. Biol. Chem. 257:14973-14978.
61. Woods, A., J.R. Couchman, S. Johansson, and M. Höök. 1986. Adhesion and cytoskeletal organization of fibroblasts in response to fibronectin fragments. EMBO (Eur. Mol. Biol. Organ.) J. 5:665-670.
62. Xia, P., and L.A. Culp. 1994. Adhesion activity in fibronectin's alternatively spliced domain EDa. 213:253-265.
63. Xia, P., and L.A. Culp. 1995. Adhesion activity in fibronectin's alternatively spliced domain EDa (EIIIA): complementarity to plasma fibronectin functions. Exp. Cell Res. 217:517-527.
64. Yamada, K.M. 1991. Fibronectin and other cell interactive glycoproteins. In Cell Biology of Extracellular Matrix. E. Hay, editor. Plenum Press, New York. 111-146.
65. Yamada, K.M., and D.W. Kennedy. 1979. Fibroblast cellular and plasma fibronectins are similar but not identical. J. Cell Biol. 80:492-498.
66. Yamada, K.M., D.H. Schlesinger, D.W. Kennedy, and I. Pastan. 1977. Characterization of a major fibroblast cell surface glycoprotein. Biochemistry. 16: 5552-5559.
67. Yamada, K.M., D.W. Kennedy, S.S. Yamada, H. Gralnick, W. Chen, and S.K. Akiyama. 1990. Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration. Cancer Res. 50:4485-4496.
68. Yang, J.T., H. Rayburn, and R.O. Hynes. 1993. Embryonic mesodermal defects in α5 integrin-deficient mice. Development. 119:1093-1105.
69. Zardi. L., B. Carnemolla, A. Siri, T.E. Petersen, G. Paolella, G. Sebastio, and F.E. Baralle. 1987. Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon. EMBO (Eur. Mol. Biol. Organ.) J. 6:2337-2342.