메뉴 건너뛰기




Volumn 16, Issue 8, 2011, Pages 649-656

Evidence for cytochrome P450 2B1/2B2 isoenzymes in freshly prepared peripheral blood lymphocytes

Author keywords

CYP; Expression; Induction; Liver; Lymphocyte; PB

Indexed keywords

CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 2B1; CYTOCHROME P450 2B2; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; PENTOXYRESORUFIN DEALKYLASE; PHENOBARBITAL; PHENYTOIN;

EID: 81855211110     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.3109/1354750X.2011.622412     Document Type: Article
Times cited : (5)

References (48)
  • 2
    • 33646794068 scopus 로고    scopus 로고
    • Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan)
    • DOI 10.1124/dmd.105.008185
    • Baldwin SJ, Bramhall JL, Ashby CA, Yue L, Murdock PR, Hood SR, Ayrton AD, Clarke SE. (2006). Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan). Drug Metab Dispos 34:1063-1069. (Pubitemid 43763766)
    • (2006) Drug Metabolism and Disposition , vol.34 , Issue.6 , pp. 1063-1069
    • Baldwin, S.J.1    Bramhall, J.L.2    Ashby, C.A.3    Yue, L.4    Murdock, P.R.5    Hood, S.R.6    Ayrton, A.D.7    Clarke, S.E.8
  • 3
    • 0031772143 scopus 로고    scopus 로고
    • Cytochrome P450 1B1: A major P450 isoenzyme in human blood monocytes and macrophage subsets
    • DOI 10.1016/S0006-2952(98)00105-1, PII S0006295298001051
    • Baron JM, Zwadlo-Klarwasser G, Jugert F, Hamann W, Rübben A, Mukhtar H, Merk HF. (1998). Cytochrome P450 1B1: A major P450 isoenzyme in human blood monocytes and macrophage subsets. Biochem Pharmacol 56:1105-1110. (Pubitemid 28511231)
    • (1998) Biochemical Pharmacology , vol.56 , Issue.9 , pp. 1105-1110
    • Baron, J.M.1    Zwadlo-Klarwasser, G.2    Jugert, F.3    Hamann, W.4    Rubben, A.5    Mukhtar, H.6    Merk, H.F.7
  • 5
    • 70349389635 scopus 로고    scopus 로고
    • Nrf2 and antioxidant defense against CYP2E1 toxicity
    • Cederbaum A. (2009). Nrf2 and antioxidant defense against CYP2E1 toxicity. Expert Opin Drug Metab Toxicol 5:1223-1244.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , pp. 1223-1244
    • Cederbaum, A.1
  • 6
    • 0034585128 scopus 로고    scopus 로고
    • Phenobarbital-induced expression of cytochrome P450 genes
    • Czekaj P. (2000). Phenobarbital-induced expression of cytochrome P450 genes. Acta Biochim Pol 47:1093-1105.
    • (2000) Acta Biochim Pol , vol.47 , pp. 1093-1105
    • Czekaj, P.1
  • 7
    • 20644468612 scopus 로고    scopus 로고
    • Evidence for cytochrome P450 2E1 catalytic activity and expression in rat blood lymphocytes
    • DOI 10.1016/j.lfs.2005.01.021, PII S0024320505003310
    • Dey A, Dhawan A, Kishore Seth P, Parmar D. (2005). Evidence for cytochrome P450 2E1 catalytic activity and expression in rat blood lymphocytes. Life Sci 77:1082-1093. (Pubitemid 40835887)
    • (2005) Life Sciences , vol.77 , Issue.10 , pp. 1082-1093
    • Dey, A.1    Dhawan, A.2    Seth, P.K.3    Parmar, D.4
  • 8
    • 0035876315 scopus 로고    scopus 로고
    • Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes: Evidence for catalytic activity and mRNA expression
    • DOI 10.1016/S0024-3205(01)01130-4, PII S0024320501011304
    • Dey A, Parmar D, Dayal M, Dhawan A, Seth PK. (2001). Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes evidence for catalytic activity and mRNA expression. Life Sci 69:383-393. (Pubitemid 32539380)
    • (2001) Life Sciences , vol.69 , Issue.4 , pp. 383-393
    • Dey, A.1    Parmar, D.2    Dayal, M.3    Dhawan, A.4    Seth, P.K.5
  • 9
    • 0037063719 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 dependent catalytic activity and lipid peroxidation in rat blood lymphocytes
    • DOI 10.1016/S0024-3205(02)02084-2, PII S0024320502020842
    • Dey A, Parmar D, Dhawan A, Dash D, Seth PK. (2002). Cytochrome P450 2E1 dependent catalytic activity and lipid peroxidation in rat blood lymphocytes. Life Sci 71:2509-2519. (Pubitemid 35247959)
    • (2002) Life Sciences , vol.71 , Issue.21 , pp. 2509-2519
    • Dey, A.1    Parmar, D.2    Dhawan, A.3    Dash, D.4    Seth, P.K.5
  • 10
    • 33748681783 scopus 로고    scopus 로고
    • Evidence for cytochrome P450 3A expression and catalytic activity in rat blood lymphocytes
    • DOI 10.1016/j.lfs.2006.06.006, PII S0024320506004498
    • Dey A, Yadav S, Dhawan A, Seth PK, Parmar D. (2006). Evidence for cytochrome P450 3A expression and catalytic activity in rat blood lymphocytes. Life Sci 79:1729-1735. (Pubitemid 44389855)
    • (2006) Life Sciences , vol.79 , Issue.18 , pp. 1729-1735
    • Dey, A.1    Yadav, S.2    Dhawan, A.3    Seth, P.K.4    Parmar, D.5
  • 11
    • 0035431686 scopus 로고    scopus 로고
    • 450 gene expression in liver and blood in patients with suspected liver disease
    • DOI 10.1007/s002280100318
    • Finnström N, Törn M, Lööf L, Rane A. (2001). Independent patterns of cytochrome P450 gene expression in liver and blood in patients with suspected liver disease. Eur J Clin Pharmacol 57:403-409. (Pubitemid 33787191)
    • (2001) European Journal of Clinical Pharmacology , vol.57 , Issue.5 , pp. 403-409
    • Finnstrom, N.1    Thorn, M.2    Loof, L.3    Rane, A.4
  • 13
    • 0346942394 scopus 로고    scopus 로고
    • Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays
    • Gerhold D, Lu M, Xu J, Austin C, Caskey CT, Rushmore T. (2001). Monitoring expression of genes involved in drug metabolism and toxicology using DNA microarrays. Physiol Genomics 5:161-170. (Pubitemid 33675213)
    • (2001) Physiological Genomics , vol.2001 , Issue.5 , pp. 161-170
    • Gerhold, D.1    Lu, M.2    Xu, J.3    Austin, C.4    Caskey, C.T.5    Rushmore, T.6
  • 16
    • 0034177265 scopus 로고    scopus 로고
    • Expression of human cytochrome P450 2B6 in Escherichia coli: Characterization of catalytic activity and expression levels in human liver
    • DOI 10.1006/abbi.2000.1708
    • Hanna IH, Reed JR, Guengerich FP, Hollenberg PF. (2000). Expression of human cytochrome P450 2B6 in Escherichia coli: Characterization of catalytic activity and expression levels in human liver. Arch Biochem Biophys 376:206-216. (Pubitemid 30205131)
    • (2000) Archives of Biochemistry and Biophysics , vol.376 , Issue.1 , pp. 206-216
    • Hanna, I.H.1    Reed, J.R.2    Guengerich, F.P.3    Hollenberg, P.F.4
  • 17
    • 41749098287 scopus 로고    scopus 로고
    • Lymphocyte cytochrome P450 expression: Inducibility studies in male Wistar rats
    • Hannon-Fletcher MP, Barnett YA. (2008). Lymphocyte cytochrome P450 expression: inducibility studies in male Wistar rats. Br J Biomed Sci 65:1-6. (Pubitemid 351488828)
    • (2008) British Journal of Biomedical Science , vol.65 , Issue.1 , pp. 1-6
    • Hannon-Fletcher, M.P.1    Barnett, Y.A.2
  • 18
    • 0024423728 scopus 로고
    • Interindividual variation among humans in carcinogen metabolism, DNA adduct formation and DNA repair
    • Harris CC. (1989). Interindividual variation among humans in carcinogen metabolism, DNA adduct formation and DNA repair. Carcinogenesis 10:1563-1566. (Pubitemid 19222251)
    • (1989) Carcinogenesis , vol.10 , Issue.9 , pp. 1563-1566
    • Harris, C.C.1
  • 19
    • 1942531624 scopus 로고    scopus 로고
    • Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes
    • DOI 10.1097/00008571-200404000-00002
    • Hesse LM, He P, Krishnaswamy S, Hao Q, Hogan K, von Moltke LL, Greenblatt DJ, Court MH. (2004). Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes. Pharmacogenetics 14:225-238. (Pubitemid 38530514)
    • (2004) Pharmacogenetics , vol.14 , Issue.4 , pp. 225-238
    • Hesse, L.M.1    He, P.2    Krishnaswamy, S.3    Hao, Q.4    Hogan, K.5    Von Moltke, L.L.6    Greenblatt, D.J.7    Court, M.H.8
  • 20
    • 0030694259 scopus 로고    scopus 로고
    • Detection of mRNA encoding xenobiotic-metabolizing cytochrome P450s in human bronchoalveolar macrophages and peripheral blood lymphocytes
    • DOI 10.1002/(SICI)1098-2744(199710)20:2<224::AID-MC9>3.0.CO;2-M
    • Hukkanen J, Hakkola J, Anttila S, Piipari R, Karjalainen A, Pelkonen O, Raunio H. (1997). Detection of mRNA encoding xenobiotic-metabolizing cytochrome P450s in human bronchoalveolar macrophages and peripheral blood lymphocytes. Mol Carcinog 20:224-230. (Pubitemid 27508886)
    • (1997) Molecular Carcinogenesis , vol.20 , Issue.2 , pp. 224-230
    • Hukkanen, J.1    Hakkola, J.2    Anttila, S.3    Piipari, R.4    Karjalainen, A.5    Pelkonen, O.6    Raunio, H.7
  • 21
    • 0037184794 scopus 로고    scopus 로고
    • Polymorphism of cytochrome P450 and xenobiotic toxicity
    • DOI 10.1016/S0300-483X(02)00492-4, PII S0300483X02004924
    • Ingelman-Sundberg M. (2002). Polymorphism of cytochrome P450 and xenobiotic toxicity. Toxicology 181-182:447-452. (Pubitemid 36015735)
    • (2002) Toxicology , vol.181-182 , pp. 447-452
    • Ingelman-Sundberg, M.1
  • 22
    • 78650582973 scopus 로고    scopus 로고
    • Induction of blood lymphocyte cytochrome P450 2E1 in early stage alcoholic liver cirrhosis
    • Khan AJ, Sharma A, Choudhuri G, Parmar D. (2011). Induction of blood lymphocyte cytochrome P450 2E1 in early stage alcoholic liver cirrhosis. Alcohol 45:81-87.
    • (2011) Alcohol , vol.45 , pp. 81-87
    • Khan, A.J.1    Sharma, A.2    Choudhuri, G.3    Parmar, D.4
  • 23
    • 0034040714 scopus 로고    scopus 로고
    • Fingerprinting of cytochrome P450 and microsomal epoxide hydrolase gene expression in human blood cells
    • Krovat BC, Tracy JH, Omiecinski CJ. (2000). Fingerprinting of cytochrome P450 and microsomal epoxide hydrolase gene expression in human blood cells. Toxicol Sci 55:352-360. (Pubitemid 30353243)
    • (2000) Toxicological Sciences , vol.55 , Issue.2 , pp. 352-360
    • Krovat, B.C.1    Tracy, J.H.2    Omiecinski, C.J.3
  • 27
    • 0023598578 scopus 로고
    • Issues in biochemical applications to risk assessment: When can lymphocytes be used as surrogate markers?
    • Lucier GW, Tompson CL. (1987). Issues in biochemical applications to risk assessment: When can lymphocytes be used as surrogate markers? Environ Health Perspect 76:187-191. (Pubitemid 18075941)
    • (1987) Environmental Health Perspectives , vol.76 , pp. 187-191
    • Lucier, G.W.1    Thompson, C.L.2
  • 29
    • 0035977901 scopus 로고    scopus 로고
    • Genetic variability in susceptibility and response to toxicants
    • DOI 10.1016/S0378-4274(01)00279-X, PII S037842740100279X
    • rd, Mohrenweiser HW, Bell DA. 2001 Genetic variability in susceptibility and response to toxicants. Toxicol Lett; 120: 269-280. (Pubitemid 32375093)
    • (2001) Toxicology Letters , vol.120 , Issue.1-3 , pp. 269-280
    • Miller III, M.C.1    Mohrenweiser, H.W.2    Bell, D.A.3
  • 32
    • 0032911542 scopus 로고    scopus 로고
    • Concise review of the cytochrome P450s and their roles in toxicology
    • DOI 10.1093/toxsci/48.2.151
    • Omiecinski CJ, Remmel RP, Hosagrahara VP. (1999). Concise review of the cytochrome P450s and their roles in toxicology. Toxicol Sci 48:151-156. (Pubitemid 29226691)
    • (1999) Toxicological Sciences , vol.48 , Issue.2 , pp. 151-156
    • Omiecinski, C.J.1    Remmel, R.P.2    Hosagrahara, V.P.3
  • 33
    • 0031735477 scopus 로고    scopus 로고
    • Immunochemical and biochemical evidence for expression of phenobarbital- and 3-methylcholanthrene-inducible isoenzymes of cytochrome P450 in rat brain
    • DOI 10.1080/109158198225883
    • Parmar D, Dhawan A, Dayal M, Seth PK. (1998). Immunochemical and biochemical evidence for expression of Phenobarbital and 3-Methylcholanthrene- inducible isoenzymes of Cytochrome P450 in rat brain. Int J Toxicol 17:619-630. (Pubitemid 28487350)
    • (1998) International Journal of Toxicology , vol.17 , Issue.6 , pp. 619-630
    • Parmar, D.1    Dhawan, A.2    Dayal, M.3    Seth, P.K.4
  • 34
    • 33646104655 scopus 로고    scopus 로고
    • Te expressions of protooncogenes and CYP1A in lungs of rats exposed to sulfur dioxide and benzo(a)pyrene
    • Qin G, Meng Z. (2006). Te expressions of protooncogenes and CYP1A in lungs of rats exposed to sulfur dioxide and benzo(a)pyrene. Regul Toxicol Pharmacol 45:36-43.
    • (2006) Regul Toxicol Pharmacol , vol.45 , pp. 36-43
    • Qin, G.1    Meng, Z.2
  • 37
    • 0030036412 scopus 로고    scopus 로고
    • Detection of CYP1A1 mRNA levels and CYP1A1 Msp 1 polymorphisms as possible biomarkers of exposure and susceptibility in smokers and non-smokers
    • DOI 10.1002/(SICI)1520-6866(1996)16:1<65::AID-TCM7>3.0.CO;2-E
    • Rumsby PC, Yardley-Jones A, Anderson D, Phillimore HE, Davies MJ. (1996). Detection of CYP1A1 mRNA levels and CYP1A1 Msp polymorphisms as possible biomarkers of exposure and susceptibility in smokers and non-smokers. Teratog Carcinog Mutagen 16:65-74. (Pubitemid 26232883)
    • (1996) Teratogenesis Carcinogenesis and Mutagenesis , vol.16 , Issue.1 , pp. 65-74
    • Rumsby, P.C.1    Yardley-Jones, A.2    Anderson, D.3    Phillimore, H.E.4    Davies, M.J.5
  • 38
    • 77249097285 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbon metabolizing cytochrome P450s in freshly prepared uncultured rat blood lymphocytes
    • Saurabh K, Sharma A, Yadav S, Parmar D. (2010). Polycyclic aromatic hydrocarbon metabolizing cytochrome P450s in freshly prepared uncultured rat blood lymphocytes. Biochem Pharmacol 79:1182-1188.
    • (2010) Biochem Pharmacol , vol.79 , pp. 1182-1188
    • Saurabh, K.1    Sharma, A.2    Yadav, S.3    Parmar, D.4
  • 39
    • 70350031110 scopus 로고    scopus 로고
    • Evidence for increased cytochrome P450 1A1 expression in blood lymphocytes of lung cancer patients
    • Shah PP, Saurabh K, Pant MC, Mathur N, Parmar D. (2009). Evidence for increased cytochrome P450 1A1 expression in blood lymphocytes of lung cancer patients. Mutat Res 670:74-78.
    • (2009) Mutat Res , vol.670 , pp. 74-78
    • Shah, P.P.1    Saurabh, K.2    Pant, M.C.3    Mathur, N.4    Parmar, D.5
  • 40
    • 34047243800 scopus 로고    scopus 로고
    • Xenobiotic-metabolizing enzymes involved in activation and detoxifcation of carcinogenic polycyclic aromatic hydrocarbons
    • Shimada T. (2006). Xenobiotic-metabolizing enzymes involved in activation and detoxifcation of carcinogenic polycyclic aromatic hydrocarbons. Drug Metab Pharmacokinet 21:257-276.
    • (2006) Drug Metab Pharmacokinet , vol.21 , pp. 257-276
    • Shimada, T.1
  • 43
    • 0027439096 scopus 로고
    • CYP1A1 mRNA levels as a human exposure biomarker: Use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes
    • Vanden Heuvel JP, Clark GC, Tompson CL, McCoy Z, Miller CR, Lucier GW, Bell DA. (1993). CYP1A1 mRNA levels as a human exposure biomarker: Use of quantitative polymerase chain reaction to measure CYP1A1 expression in human peripheral blood lymphocytes. Carcinogenesis 14:2003-2006. (Pubitemid 23311423)
    • (1993) Carcinogenesis , vol.14 , Issue.10 , pp. 2003-2006
    • Vanden Heuvel, J.P.1    Clark, G.C.2    Thompson, C.L.3    McCoy, Z.4    Miller, C.R.5    Lucier, G.W.6    Bell, D.A.7
  • 44
    • 18144441941 scopus 로고    scopus 로고
    • The relationship between polymorphisms of xenobiotic metabolizing enzymes and susceptibility to cancer
    • DOI 10.1016/S0300-483X(02)00450-X, PII S0300483X0200450X
    • Vineis P. (2002). Te relationship between polymorphisms of xenobiotic metabolizing enzymes and susceptibility to cancer. Toxicology 181-182:457-462. (Pubitemid 36015737)
    • (2002) Toxicology , vol.181-182 , pp. 457-462
    • Vineis, P.1
  • 45
    • 3142764845 scopus 로고    scopus 로고
    • Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin
    • DOI 10.1074/jbc.M400580200
    • Wang H, Faucette S, Moore R, Sueyoshi T, Negishi M, LeCluyse E. (2004). Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin. J Biol Chem 279:29295-29301. (Pubitemid 38915806)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.28 , pp. 29295-29301
    • Wang, H.1    Faucette, S.2    Moore, R.3    Sueyoshi, T.4    Negishi, M.5    LeCluyse, E.6
  • 46
    • 0026512675 scopus 로고
    • Phenobarbital induction of cytochrome P-450 gene expression
    • Waxman DJ, Azarof L. (1992). Phenobarbital induction of cytochrome P-450 gene expression. Biochem J 281 (Pt 3):577-592.
    • (1992) Biochem J , vol.281 , Issue.PART 3 , pp. 577-592
    • Waxman, D.J.1    Azarof, L.2
  • 47
    • 24644494404 scopus 로고    scopus 로고
    • Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1
    • Wu D, Cederbaum AI. (2005). Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1. Toxicol Appl Pharmacol 207:70-76.
    • (2005) Toxicol Appl Pharmacol , vol.207 , pp. 70-76
    • Wu, D.1    Cederbaum, A.I.2
  • 48
    • 23944487083 scopus 로고    scopus 로고
    • Di-n-butyl phthalate activates constitutive androstane receptor and pregnane X receptor and enhances the expression of steroid-metabolizing enzymes in the liver of rat fetuses
    • DOI 10.1093/toxsci/kfi204
    • Wyde ME, Kirwan SE, Zhang F, Laughter A, Hofman HB, Bartolucci-Page E, Gaido KW, Yan B, You L. (2005). Di-n-butyl phthalate activates constitutive androstane receptor and pregnane X receptor and enhances the expression of steroid-metabolizing enzymes in the liver of rat fetuses. Toxicol Sci 86:281-290. (Pubitemid 41418641)
    • (2005) Toxicological Sciences , vol.86 , Issue.2 , pp. 281-290
    • Wyde, M.E.1    Kirwan, S.E.2    Zhang, F.3    Laughter, A.4    Hoffman, H.B.5    Bartolucci-Page, E.6    Gaido, K.W.7    Yan, B.8    You, L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.