Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: A case-control study in an Italian population

BMC Cancer

Volumn 7, Issue , 2007, Pages

  Boccia, Stefania ^a   Sayed Tabatabaei, Fakhredin A ^b   Persiani, Roberto ^a   Gianfagna, Francesco ^a   Rausei, Stefano ^a   Arzani, Dario ^a   La Greca, Antonio ^a   D'Ugo, Domenico ^a   La Torre, Giuseppe ^a   van Duijn, Cornelia M ^c   Ricciardi, Gualtiero ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b MEDICINES EVALUATION BOARD   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; CYTOCHROME P450 1A1; CYTOCHROME P450 2E1; EPOXIDE HYDROLASE; GENE PRODUCT; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; PROTEIN EPHX 1; SULFOTRANSFERASE; SULFOTRANSFERASE 1A1; UNCLASSIFIED DRUG; ARYL SULFOTRANSFERASE; GLUTATHIONE S-TRANSFERASE M1; GLUTATHIONE S-TRANSFERASE T1; GLUTATHIONE TRANSFERASE; NAT2 PROTEIN, HUMAN; SULT1A1 PROTEIN, HUMAN; TUMOR MARKER; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; ATTRIBUTABLE RISK; CANCER RISK; CANCER SUSCEPTIBILITY; CIGARETTE SMOKING; CONTROLLED STUDY; DNA POLYMORPHISM; EXON; FEMALE; GASTRECTOMY; GENE FREQUENCY; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC SUSCEPTIBILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HAPLOTYPE; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; ITALY; MAJOR CLINICAL STUDY; MALE; STOMACH ADENOCARCINOMA; STOMACH CARCINOGENESIS; TUMOR LOCALIZATION; CASE CONTROL STUDY; COMPARATIVE STUDY; DRINKING BEHAVIOR; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; RISK FACTOR; SMOKING; STOMACH TUMOR;

AGED; ALCOHOL DRINKING; ARYLAMINE N-ACETYLTRANSFERASE; ARYLSULFOTRANSFERASE; CASE-CONTROL STUDIES; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2E1; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RISK FACTORS; SMOKING; STOMACH NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 38149069626     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-7-206     Document Type: Article

References (37)

1. Verdecchia A Mariotto A Gatta G Bustamante-Teixeira MT Ajiki W Comparison of stomach cancer incidence and survival in four continents Eur J Cancer 2003, 39:1603-1609 10.1016/S0959-8049(03)00360-5 12855268
2. Correa P Schneider BG Etiology of gastric cancer: What is new? Cancer Epidemiol Biomarkers Prev 2005, 14:1865-1868 10.1158/ 1055-9965.EPI-05-0029 16103427
3. Aoki M Yamamoto K Noshiro H Sakai K Yokota J Kohno T Tokino T Ishida S Ohyama S Ninomiya I Uesaka K Kitajima M Shimada S Matsuno S Yano M Hiratsuka M Sugimura H Itoh F Minamoto T Maehara Y Takenoshita S Aikou T Katai H Yoshimura K Takahashi T Akagi K Sairenji M Yamamura Y Sasazuki T A full genome scan for gastric cancer J Med Genet 2005, 42:83-7 10.1136/ jmg.2004.021782 15635081
4. Gonzalez CA Sala N Capella G Genetic susceptibility and gastric cancer risk Int J Cancer 2002, 100:249-260 10.1002/ijc.10466 12115538
5. Garte S Gaspari L Alexandrie AK Ambrosone C Autrup H Autrup JL Baranova H Bathum L Benhamou S Boffetta P Bouchardy C Breskvar K Brockmoller J Cascorbi I Clapper ML Coutelle C Daly A Dell'Omo M Dolzan V Dresler CM Fryer A Haugen A Hein DW Hildesheim A Hirvonen A Hsieh LL Ingelman-Sundberg M Kalina I Kang D Kihara M Kiyohara C Kremers P Lazarus P Le Marchand L Lechner MC van Lieshout EMM London S Manni JJ Maugard CM Morita S Nazar-Stewart V Noda K Oda Y Parl FF Pastorelli R Persson I Peters WHM Rannug A Rebbeck T Risch A Roelandt L Romkes M Ryberg D Salagovic J Schoket B Seidegard J Shields PG Sim E Sinnet D Strange RC Stücker I Sugimura H To-Figueras J Vineis P Yu MC Taioli E Metabolic gene polymorphism frequencies in control populations Cancer Epidemiol Biomarkers Prev 2001, 10:1239-1248 11751440
6. Boccia S Persiani R La Torre G Rausei S Arzani D Gianfagna F Romano-Spica V D'Ugo D Ricciardi G Sulfotransferase 1A1 polymorphism and gastric cancer risk: A pilot case-control study Cancer Lett 2005, 229:235-243 10.1016/j.canlet.2005.06.035 16137826
7. La Torre G Boccia S Ricciardi G Glutathione S-transferase M1 status and gastric cancer risk: A meta-analysis Cancer Lett 2005, 217:53-60 10.1016/ j.canlet.2004.08.020 15596296
8. Boccia S La Torre G Gianfagna F Mannocci A Ricciardi G Meta-analysis of GSTT1 and gastric cancer Mutagenesis 2006, 3:1432-1435
9. Martinez C Martin F Fernandez JM Garcia-Martin E Sastre J Diaz-Rubio M Agundez JA Ladero JM Glutathione S-transferases mu 1, theta 1, pi 1, alpha 1 and mu 3 genetic polymorphisms and the risk of colorectal and gastric cancers in humans Pharmacogenomics 2006, 7:11-18 10.2217/ 14622416.7.5.711
10. Boccia S La Torre G Gianfagna F Mannocci A Ricciardi G N-Acetyltransferase 2 status and gastric cancer risk: A preliminary meta-analysis Ital J Public Health 2005, 2:53-57
11. Boccia S De Lauretis A Gianfagna F van Dujin CM Ricciardi G Cytochrome p450 2E1 5′-flanking region polymorphism and its interaction with alcohol, tobacco and GSTs in gastric cancer susceptibility: A meta-analysis of the literature Carcinogenesis 2007, 28:101-6 10.1093/ carcin/bgl124 16837478
12. Jourenkova-Mironova N Mitrunen K Bouchardy C Dayer P Benhamou S Hirvonen A High-activity microsomal epoxide hydrolase genotypes and the risk of oral, pharynx, and larynx cancers Cancer Res 2000, 60:534-536 10676631
13. Taningher M Malacarne D Izzotti A Ugolini D Parodi S Drug metabolism polymorphisms as modulators of cancer susceptibility Mutat Res 1999, 436:227-261 10.1016/S1383-5742(99)00005-8 10354524
14. Suzuki S Muroishi Y Nakanishi I Oda Y Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 gene point mutations in Japanese patients with gastric cancer J Gastroenterol 2004, 39:220-230 10.1007/s00535-003-1281-x 15064998
15. Agudo A Sala N Pera G Capella G Berenguer A Garcia N Palli D Boeing H Del Giudice G Saieva C Carneiro F Berrino F Sacerdote C Tumino R Panico S Berglund G Siman H Stenling R Hallmans G Martinez C Amiano P Barricarte A Navarro C Quiros JR Allen N Key T Bingham S Khaw KT Linseisen J Nagel G Overvad K Tjonneland A Olsen A Bueno-de-Mesquita HB Boshuizen HC Peeters PH Numans ME Clavel-Chapelon F Boutron-Ruault MC Trichopoulou A Lund E Blaker H Jenab M Ferrari P Norat T Riboli E Gonzalez CA No association between polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the risk of gastric adenocarcinoma in the European prospective investigation into cancer and nutrition Cancer Epidemiol Biomarkers Prev 2006, 15:1043-1045 10.1158/1055-9965.EPI-06-0073 16702391
16. Boccia S Gianfagna F Persiani R La Greca A Arzani D Rausei S D'Ugo D Magistrelli P Villari P van Duijn CM Ricciardi G Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population Biomarkers 2007, 12:635-644 10.1080/13547500701546766 17972183
17. Lauren P The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification Acta Pathol Microbiol Scand 1965, 64:31-49 14320675
18. Sobin LH Wittekind C TNM classification of malignant tumors, UICC New York: Wiley-Liss 2002
19. Arand M Muhlbauer R Hengstler J Jager E Fuchs J Winkler L Oesch F A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms Anal Biochem 1996, 236:184-186 10.1006/abio.1996.0153 8619490
20. Coughtrie MW Gilissen RA Shek B Strange RC Fryer AA Jones PW Bamber DE Phenol sulphotransferase SULT1A1 polymorphism: Molecular diagnosis and allele frequencies in Caucasian and African populations Biochem J 1999, 337:45-49 1219934 9854023 10.1042/0264-6021:3370045
21. Sarmanova J Tynkova L Susova S Gut I Soucek P Geneticpolymorphisms of biotransformation enzymes: Allele frequencies in thepopulation of the Czech Republic Pharmacogenetics 2000, 10:781-788 10.1097/ 00008571-200012000-00003 11191882
22. Peluso M Airoldi L Armelle M Martone T Coda R Malaveille C Giacomelli G Terrone C Casetta G Vineis P White blood cell DNA adducts, smoking, and NAT2 and GSTM1 genotypes in bladder cancer: A case-control study Cancer Epidemiol Biomarkers Prev 1998, 7:341-346 9568791
23. Hung RJ Boffetta P Brennan P Malaveille C Hautefeuille A Donato F Gelatti U Spaliviero M Placidi D Carta A Scotto di Carlo A Porru S GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high-risk population Int J Cancer 2004, 110:598-604 10.1002/ijc.20157 15122594
24. Smith CA Harrison DJ Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema Lancet 1997, 350:630-633 10.1016/S0140-6736(96)08061-0 9288046
25. Rothman KJ Measuring interactions Epidemiology: An introduction New York: Oxford University press Rothman KJ 2002:168-90
26. Andersson T Alfredsson L Kallberg H Zdravkovic S Ahlbom A Calculating measures of biological interaction Eur J Epidemiol 2005, 20:575-579 10.1007/s10654-005-7835-x 16119429
27. Bagnardi V Blangiardo M La Vecchia C Corrao G A meta-analysis of alcohol drinking and cancer risk Br J Cancer 2001, 85:1700-1705 10.1054/ bjoc.2001.2140 11742491
28. Lynch HT Grady W Suriano G Huntsman D Gastric cancer: New genetic developments J Surg Oncol 2005, 90:114-33 10.1002/jso.20214 15895459
29. Ioannidis JPA Meta-analysis in public health: Potential and problems Ital J Public Health 2006, 3:9-14
30. Agudo A Sala N Pera G Capella G Berenguer A Garcia N Palli D Boeing H Del Giudice G Saieva C Carneiro F Berrino F Sacerdote C Tumino R Panico S Berglund G Siman H Stenling R Hallmans G Marti nez C Bilbao R Barricarte A Navarro C Quiros JR Allen N Key T Bingham S Khaw KT Linseisen J Nagel G Overvad K Tjonneland A Olsen A Bueno-de-Mesquita HB Boshuizen HC Peeters PH Numans ME Clavel-Chapelon F Boutron-Ruault MC Trichopoulou A Lund E Offerhaus J Jenab M Ferrari P Norat T Riboli E Gonzalez CA Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition Cancer Epidemiol Biomarkers Prev 2006, 15:2427-34 10.1158/1055-9965.EPI-06-0072 17164366
31. Cordell HJ Clayton DG Genetic association studies Lancet 2005, 366:1121-1131 10.1016/S0140-6736(05)67424-7 16182901
32. Wu MS Chen CJ Lin MT Wang HP Shun CT Sheu JC Lin JT Genetic polymorphisms of cytochrome p450 2E1, glutathione S-transferase M1 and T1, and susceptibility to gastric carcinoma in Taiwan Int J Colorectal Dis 2002, 17:338-343 10.1007/s00384-001-0383-2 12172927
33. Park GT Lee OY Kwon SY Lee CG Yoon BC Hahm JS Lee MH Hoo Lee D Kee CS Sun HS Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans J Gastroenterol Hepatol 2003, 18:1257-1263 10.1046/j.1440-1746.2003.03167.x 14535982
34. Li D Dandara C Parker MI Association of cytochrome P450 2E1 genetic polymorphisms with squamous cell carcinoma of the oesophagus Clin Chem Lab Med 2005, 43(4):370-375 10.1515/CCLM.2005.067 15899651
35. Cederbaum AI CYP2E1: Biochemical and toxicological aspects and role in alcohol-induced liver injury Mt Sinai J Med 2006, 73(4):657-672 16878272
36. Uematsu F Ikawa S Kikuchi H Sagami I Kanamaru R Abe T Satoh K Motomiya M Watanabe M Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: Possible relevance to low smoking exposure Pharmacogenetics 1994, 4(2):58-63 10.1097/00008571-199404000-00002 7915935
37. Rothman KJ Greenland S Causation and causal inference in epidemiology Am J Public Health 2005, 95:S144-150 10.2105/AJPH.2004.059204 16030331