The relationship between polymorphisms of xenobiotic metabolizing enzymes and susceptibility to cancer

Toxicology

Volumn 181-182, Issue , 2002, Pages 457-462

  Vineis, Paolo ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Enzyme; Polymorphisms; Susceptibility

Indexed keywords

CYTOCHROME P450 1A1;

ARTICLE; BLADDER CANCER; CANCER RISK; CANCER SUSCEPTIBILITY; CARCINOGENESIS; ENVIRONMENTAL EXPOSURE; ETHNIC GROUP; EXON; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; LUNG CANCER; PRIORITY JOURNAL; RISK FACTOR; SMOKING; XENOBIOTIC METABOLISM;

CARCINOGENS; ENVIRONMENT; HUMANS; MODELS, BIOLOGICAL; NEOPLASMS; PENETRANCE; POLYMORPHISM, GENETIC; XENOBIOTICS;

EID: 18144441941     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(02)00450-X     Document Type: Article

References (9)

1. Vineis, P., Malats, N., Lang, M., d'Errico, A., Caporaso, N., Cuzick, J., Boffetta, P. 1999. Metabolic polymorphisms and susceptibility to cancer. IARC Scie. Publ. No. 148, International Agency for Research on Cancer, Lyon.
2. Vogelstein B., Kinzler K.W. The Genetic Basis of Human Cancer. 1998;McGraw-Hill, New York.
3. Garte, S., Taioli, E. 2000. Ethnic and geographic distribution of metabolic gene polymorphisms in a large sample of healthy controls: Results from the GSEC study. AACR Proceedings, vol 41, San Francisco.
4. Matullo G., Palli D., Peluso M., Guarrera S., Carturan S., Celentano E., Krogh V., Munnia A., Tumino R., Polidoro S., Piazza A., Vineis P. XRCC1, XRCC3, XPD gene polymorphisms. smoking and (32)P-DNA adducts in a sample of health subjects. Carcinogenesis. 22:2001;1437-1445.
5. Nakachi K., Imai K., Hayashi S., Kawajiri K. Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population. Cancer Res. 53:(13):1993;2994-2999.
6. Ishibe N., Wiencke J.K., Zuo Z.F., et al. Susceptibility to lung cancer in light smokers associated with CYP1A1 polymorphisms in Mexican- and African-Americans. Cancer Epidemiol. Biomarkers Prev. 6:1997;1075.
7. Hamada G.S., Sugimura H., Suzuki I., et al. The heme-binding region polymorphism of cytochrome P450IA1 (CypIA1), rather than the RsaI polymorphism of IIE1 (CypIIE1), is associated with lung cancer in Rio de Janeiro. Cancer Epidemiol. Biomarkers Prev. 4:1995;63.
8. Burnet N.G., Johansen J., Turesson I., Nyman J., Peacock J.H. Describing patients' normal tissue reactions concerning the possibility of individualising radiotherapy dose prescriptions based on potential predictive assays of normal tissue radiosensitivity. Int. J. Cancer. 79:1998;606-613.
9. Pott F, Heinrich U. 1990. Relative significance of different hydrocarbons for the carcinogenic potency of emissions from various incomplete combustion processes." In: H. Vainio, M. Sorsa, A.J. McMichael (Eds.), Complex mixtures and cancer risk. IARC Scie. Publ. No. 104, IARC, Lyon.