Biological constraints that limit compensation of a common skeletal trait variant lead to inequivalence of tibial function among healthy young adults

Journal of Bone and Mineral Research

Volumn 26, Issue 12, 2011, Pages 2872-2885

  Jepsen, Karl J ^a   Centi, Amanda ^b   Duarte, G Felipe ^a   Galloway, Kathleen ^c   Goldman, Haviva ^d   Hampson, Naomi ^d   Lappe, Joan M ^e   Cullen, Diane M ^e   Greeves, Julie ^f   Izard, Rachel ^f   Nindl, Bradley C ^b   Kraemer, William J ^g   Negus, Charles H ^h   Evans, Rachel K ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b U S ARMY RESEARCH INSTITUTE OF ENVIRONMENTAL MEDICINE   (United States)

^c BELMONT UNIVERSITY   (United States)

^d DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^e CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f HQ Army Recruiting and Training Division   (United Kingdom)

^g UNIVERSITY OF CONNECTICUT   (United States)

^h TITAN CORPORATION   (United States)

Author keywords

complex systems; functional inequivalence; robustness; strength; tibia

Indexed keywords

ADULT; ARTICLE; BODY SIZE; BONE BOWING; BONE CELL; BONE CHARACTERISTICS AND FUNCTIONS; BONE DENSITY; BONE MINERALIZATION; BONE REMODELING; BONE STIFFNESS; BONE STRENGTH; BONE WIDTH; COMPUTER ASSISTED TOMOGRAPHY; DIAPHYSIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATH ANALYSIS; POROSITY; QUANTITATIVE ANALYSIS; SEX DIFFERENCE; TIBIA; YOUNG MODULUS;

BONE DENSITY; FEMALE; HEALTH; HUMANS; MALE; MODELS, BIOLOGICAL; PHENOTYPE; POROSITY; QUANTITATIVE TRAIT, HERITABLE; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; TIBIA; TOMOGRAPHY, X-RAY COMPUTED; YOUNG ADULT;

EID: 81855184651     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.497     Document Type: Article

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