Tibial geometry is associated with failure load ex vivo: A MRI, pQCT and DXA study

Osteoporosis International

Volumn 18, Issue 7, 2007, Pages 991-997

  Liu, D ^a   Manske, S L ^a,b   Kontulainen, S A ^a,c   Tang, C ^a   Guy, P ^a   Oxland, T R ^a   McKay, H A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Bone strength; Fracture; Magnetic resonance imaging; Peripheral quantitative computed tomography; Tibia diaphysis

Indexed keywords

AGED; ARTICLE; BONE DENSITY; CADAVER; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORRELATION COEFFICIENT; CORTICAL BONE; DUAL ENERGY X RAY ABSORPTIOMETRY; EX VIVO STUDY; FEMALE; GEOMETRY; HUMAN; HUMAN TISSUE; LOADING TEST; MALE; MECHANICAL STRESS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TIBIA;

ABSORPTIOMETRY, PHOTON; AGED; AGED, 80 AND OVER; CADAVER; DIAPHYSES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MODELS, BIOLOGICAL; PREDICTIVE VALUE OF TESTS; TIBIA; TIBIAL FRACTURES; WEIGHT-BEARING;

EID: 34249998971     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-007-0325-0     Document Type: Article

References (34)

1. Hudelmaier M, Kuhn V, Lochmüller EM, Well H, Priemel M, Link TM, Eckstein F (2004) Can geometry-based parameters from pQCT and material parameters from quantitative ultrasound (QUS) improve the prediction of radial bone strength over that by bone mass (DXA)? Osteoporos Int 15:375-381
2. Lochmüller EM, Zeller JB, Kaiser D, Eckstein F, Landgraf J, Putz R, Steldinger R (1998) Correlation of femoral and lumbar DXA and calcaneal ultrasound, measured in situ with intact soft tissues, with the in vitro failure loads of the proximal femur. Osteoporos Int 8:591-598
3. Bouxsein ML, Coan BS, Lee SC (1999) Prediction of the strength of the elderly proximal femur by bone mineral density and quantitative ultrasound measurements of the heel and tibia. Bone 25:49-54
4. Sievanen H (2000) A physical model for dual-energy X-ray absorptiometry-derived bone mineral density. Invest Radiol 35:325-330
5. Bolotin HH, Sievanen H, Grashuis JL (2003) Patient-specific DXA bone mineral density inaccuracies: quantitative effects of nonuniform extraosseous fat distributions. J Bone Miner Res 18:1020-1027
6. Delmas PD, Seeman E (2004) Changes in bone mineral density explain little of the reduction in vertebral or nonvertebral fracture risk with anti-resorptive therapy. Bone 34:599-604
7. Bolotin HH (2001) Inaccuracies inherent in dual-energy X-ray absorptiometry in vivo bone mineral densitometry may flaw osteopenic/ osteoporotic interpretations and mislead assessment of antiresorptive therapy effectiveness. Bone 28:548-555
8. Gomberg BR, Wehrli FW, Vasilic B, Weening RH, Saha PK, Song HK, Wright AC (2004) Reproducibility and error sources of micro-MRI-based trabecular bone structural parameters of the distal radius and tibia. Bone 35:266-276
9. Wehrli FW, Hilaire L, Fernandez-Seara M, Gomberg BR, Song HK, Zemel B, Loh L, Snyder PJ (2002) Quantitative magnetic resonance imaging in the calcaneus and femur of women with varying degrees of osteopenia and vertebral deformity status. J Bone Miner Res 17:2265-2273
10. Wehrli FW, Leonard MB, Saha PK, Gomberg BR (2004) Quantitative high-resolution magnetic resonance imaging reveals structural implications of renal osteodystrophy on trabecular and cortical bone. J Magn Reson Imaging 20:83-89
11. Gomberg BR, Saha PK, Wehrli FW (2005) Method for cortical bone structural analysis from magnetic resonance images. Acad Radiol 12:1320-1332
12. Heinonen A, McKay HA, Whittall KP, Forster BB, Khan KM (2001) Muscle cross-sectional area is associated with specific site of bone in prepubertal girls: a quantitative magnetic resonance imaging study. Bone 29:388-392
13. Hogler W, Blimkie CJ, Cowell CT, Kemp AF, Briody J, Wiebe P, Farpour-Lambert N, Duncan CS, Woodhead HJ (2003) A comparison of bone geometry and cortical density at the mid-femur between prepuberty and young adulthood using magnetic resonance imaging. Bone 33:771-778
14. Woodhead HJ, Kemp AF, Blimkie CJR, Briody JN, Duncan CS, Thompson M, Lam A, Howman-Giles R, Cowell CT (2001) Measurement of midfemoral shaft geometry: repeatability and accuracy using magnetic resonance imaging and dual-energy X-ray absorptiometry. J Bone Miner Res 16:2251-2259
15. Rauch F, Schoenau E (2001) Changes in bone density during childhood and adolescence: an approach based on bone's biological organization. J Bone Miner Res 16:597-604
16. Russo CR, Lauretani F, Bandinelli S, Bartali B, Di Iorio A, Volpato S, Guralnik JM, Harris T, Ferrucci L (2003) Aging bone in men and women: beyond changes in bone mineral density. Osteoporos Int 14:531-538
17. Kontulainen SA, Macdonald HM, Khan KM, McKay HA (2005) Examining bone surfaces across puberty: a 20-month pQCT trial. J Bone Miner Res 20:1202-1207
18. Moyer-Mileur LJ, Xie B, Ball SD, Pratt T (2003) Bone mass and density response to a 12-month trial of calcium and vitamin D supplement in preadolescent girls. J Musculoskelet Neuronal Interact 3:63-70
19. Chan K, Qin L, Lau M, Woo J, Au S, Choy W, Lee K, Lee S (2004) A randomized, prospective study of the effects of Tai Chi Chun exercise on bone mineral density in postmenopausal women. Arch Phys Med Rehabil 85:717-722
20. Liu-Ambrose TY, Khan KM, Eng JJ, Heinonen A, McKay HA (2004) Both resistance and agility training increase cortical bone density in 75- to 85-year-old women with low bone mass: a 6-month randomized controlled trial. J Clin Densitom 7:390-398
21. Manske SL, Kontulainen S, Liu D, McKay HA (Submitted) Are MRI-derived measures of cortical bone geometry reliable and accurate?: Comparison with bone histomorphometry in the human distal tibia
22. Kontulainen S, Liu D, Manske SL, Jamieson M, Sievanen H, McKay HA (2007) Analysing cortical bone cross-sectional geometry by peripheral QCT: Comparison with bone histomorphometry. J Clin Densitom (in press)
23. Hologic (1996) Hologic Model QDR-4500 Users guide. MA, Waltham
24. American Society for Testing and Materials (1989) Standard test methods for flexural properties of un-reinforced and reinforced plastics and electrical insulating materials
25. Cristofolini L, Viceconti M (2000) Mechanical validation of whole bone composite tibia models. J Biomech 33:279-288
26. Heiner AD, Brown TD (2001) Structural properties of a new design of composite replicate femurs and tibias. J Biomech 34:773-781
27. An YH, Draughn RA (1999) Mechanical testing of bone and the bone-implant interface. CRC Press LLC, Boca Raton, Florida, USA
28. Lochmüller EM, Lill CA, Kuhn V, Schneider E, Eckstein F (2002) Radius bone strength in bending, compression, and falling and its correlation with clinical densitometry at multiple sites. J Bone Miner Res 17:1629-1638
29. Manske SL, Liu-Ambrose T, de Bakker PM, Liu D, Kontulainen S, Guy P, Oxland TR, McKay HA (2006) Femoral neck cortical geometry measured with magnetic resonance imaging is associated with proximal femur strength. Osteoporos Int 17:1539-1545
30. Levenston ME, Beaupre GS, van der Meulen MC (1994) Improved method for analysis of whole bone torsion tests. J Bone Miner Res 9:1459-1465
31. Bousson V, Bergot C, Meunier A, Barbot F, Parlier-Cuau C, Laval-Jeantet AM, Laredo JD (2000) CT of the middiaphyseal femur: cortical bone mineral density and relation to porosity. Radiology 217:179-187
32. Currey JD (1999) What determines the bending strength of compact bone? The Journal of experimental biology 202:2495-2503
33. Lochmüller EM, Groll O, Kuhn V, Eckstein F (2002) Mechanical strength of the proximal femur as predicted from geometric and densitometric bone properties at the lower limb versus the distal radius. Bone 30:207-216
34. Eckstein F, Kuhn V, Lochmüller EM (2004) Strength prediction of the distal radius by bone densitometry-evaluation using biomechanical tests. Ann Biomed Eng 32:487-503