Anti-cancer activity of human colon cancer (HT-29) cell line from different fraction of Zanthoxylum schnifolium fruits

Korean Journal of Pharmacognosy

Volumn 42, Issue 3, 2011, Pages 282-287

  Han, Woong ^a   Hu, Weicheng ^a   Lee, Young Mee ^a  

^a Kangwon National University   (South Korea)

Author keywords

Anti cancer; HT 29 cells; Human colon cancer cells; ROS; Zanthoxylum schnifolium

Indexed keywords

ACETIC ACID ETHYL ESTER; PLANT EXTRACT; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SURVIVIN; UNCLASSIFIED DRUG; ZANTHOXYLUM SCHNIFOLIUM EXTRACT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL FRACTIONATION; CELL PROLIFERATION; CELL STRAIN HT29; COLON CANCER; DOSE RESPONSE; DOWN REGULATION; HUMAN; HUMAN CELL; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; ZANTHOXYLUM; ZANTHOXYLUM SCHNIFOLIUM;

EID: 81855177266     PISSN: 02533073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Korean source
2. Lee, M. S. and Chung, M. S. (2000) Analysis of volatile flavor components from Zanthoxylum schinifolium and sensory evaluation as natural spice. Korean J. Soc. Food Sci. 16: 216-220.
3. Jang, M. J., Woo, M. H., Kim, Y. H., Jun, D. Y. and Rhee, S. J. (2005) Effects of antioxidative, DPPH radical scavenging activity and antithrombogenic by the extract of Sancho(Zanthoxylum schinifolium). Korea J. Nutrition. 38: 386-394.
4. Kim, J. H. (2003) Variation of the leaf monoterpenes concentration of Zanthoxylum schinifolium at Mt. Muhak. J. Basic Sci. 18: 137-149.
5. Lim, S. J., Han, H. K. and Ko, J. H. (2003) Effects of edible and medicinal plants intake on blood glucose, glycogen and protein levels in streptozotocin induced diabetic rats. Korean J. Nutrition. 36: 981-989.
6. Kim, J. S., Jun, D. Y., Woo, M. H., Rhee, I. K. and Kim, Y. H. (2006) Chemical composition and antitumor apoptogenic activity of methylene chloride extracts from the leaves of Zanthoxylum schinifolium. J. life sci. 16: 546-554.
7. Jang, M., Lee, J. H., Seo, J. and Kim, G. H. (2010) Antibacterial Activities of Essential Oil from Zanthoxylum schinifolium Against Food-Borne Pathogens. Korean J. Food Cookery Sci. 26: 206-213.
8. Jang, H. S., Rhee, S. J. Woo, M. H. and Cho, S. H. (2007) Anti-thrombogenic and anti-inflammention effect of solvent fraction from leaves of Zanthoxylum schinifolium (Sancho Namu) in rat fed high fat diet. Korean J. Nutrition 40: 606-615.
9. Chen, I. S., Lin, Y. Tsai, I. L., Teng, C. M., Ko, F. N., Ishikawa, T. and Ishii, H. (1995) Coumarins and anti-platelet aggregation constituents from Zanthoxylum schinifolium. Phytochemistry 39: 1091-1097.
10. Kim, S. I. and Han, Y. S. (1997) Isolation and identification of antimicrobial compound from sancho (Zanthoxylum schinifolium). Korean J. Food Sci. Technol. 13: 56-63.
11. Kim, J. S., Koo, K. M. and Jung, Y. H. (2004) Antimicrobial activities of Zanthoxylum schinifolium extract against Vibrio parahaemolyticus. Korean J. Food Sci. Nutr. 33: 500-504.
12. Yoon, D. H. and Choi, Y. S. (2008) Influence of red pepper (Capsicum annuum L.) seed oil and sancho (Zanthoxylum schinifolium) seed oil on serum and liver lipids profiles in rats. Korean J. Food Sci. Technol. 40: 96-100.
13. Oh S. M., Han, W. and Wang, M. H. (2010) Antioxidant and α-glucosidase Inhibition Activity from Different Extracts of Zanthoxylum schnifolium Fruits. Kor. J. Pharmacogn. 41: 130-135.
14. Han W. and Wang, M. H. (2010) Radical Scavenging and Anti-inflammation Activities from Different Extracts of Zanthoxylum schnifolium Fruits. Kor. J. Pharmacogn. 41: 250-254.
15. Sauer, H., Wartenberg, M. and Hescheler, J. (2001) Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell. Physiol. Biochem. 11: 173-186.
16. Kuo, P. L., Chen, C. Y. and Hsu, Y. L. (2007) Isoobtusilactone a induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells. Cancer Res. 67: 7406-7420.
17. Korsmeyer, S. J. (1995) Regulators of cell death. Trends Genet. 11: 101-105.
18. Debatin, K. M. (2004) Apoptosis pathways in cancer and cancer therapy. Cancer Immunol. Immunother. 53: 153-159.
19. Paoluzzi, L. and O'Connor, O. A. (2010) Targeting survival pathways in lymphoma. Adv. Exp. Med. Biol. 687: 79-96.
20. Desai, A., Vyas, T. and Amiji, M. (2008) Cytotoxicity and apoptosis enhancement in brain tumor cells upon coadministration of paclitaxel and ceramide in nanoemulsion formulations. J. Pharm. Sci. 97: 2745-275.
21. Yin, Y., Heo, S. I., Roh, K. S. and Wang, M. H. (2009) Biological activities of fractions from methanolic extract of Picrasma quassioides. J. Plant Biol. 52: 325-331.
22. Wang, L., Xu, M. L., Hu, J. H., Rasmussen, S. K. and Wang, M. H. (2011) Codonopsis lanceolata extract induces G0/G1 arrest and apoptosis in human colon tumor HT-29 cells-Involvement of ROS generation and polyamine depletion. Food and Chemical Toxicology 49: 149-154.
23. Ling, Y. H., Liebes, L., Zou, Y. Y. and Perez-Soler, R. (2003) Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novelproteasome inhibitor, in human H460 non-small cell lung cancer cells. J. Biol. Chem. 278: 33714-33723.
24. Zhang, Y. D. and Chen, F. (2004) Reactive oxygen species (ROS), troublemakers between nuclear factor-jB (NF-jB) and c-Jun NH2-terminal kinase (JNK). Cancer Res. 64: 1902-1905.
25. Moungjaroen, J., Nimmannit, U., Callery, P. S., Wang, L. Y., Azad, N., Lipipun, V., Chanvorachote, P. and Rojanasakul, Y. (2006) Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation. J. Pharmacol. Exp. Ther. 319: 1062-1069.