Codonopsis lanceolata extract induces G0/G1 arrest and apoptosis in human colon tumor HT-29 cells - Involvement of ROS generation and polyamine depletion

Food and Chemical Toxicology

Volumn 49, Issue 1, 2011, Pages 149-154

  Wang, Lan ^a   Xu, Ming Lu ^b   Hu, Jian He ^b   Rasmussen, Sren K ^c   Wang, Myeong Hyeon ^a  

^a Kangwon National University   (South Korea)

^b HENAN INSTITUTE OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Apoptosis; Codonopsis lanceolata; Polyamines depletion; ROS generation

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CODONOPSIS LANCEOLATA EXTRACT; PLANT EXTRACT; POLYAMINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SURVIVIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL STRAIN HT29; CODONOPSIS; CODONOPSIS LANCEOLATA; COLON TUMOR; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; POLYAMINE METABOLISM; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CODONOPSIS; G0 PHASE; G1 PHASE; HT29 CELLS; HUMANS; PLANT EXTRACTS; POLYAMINES; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

CODONOPSIS LANCEOLATA;

EID: 78650302190     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.10.010     Document Type: Article

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