-
1
-
-
3042782819
-
Microsatellites: Simple sequences with complex evolution
-
DOI 10.1038/nrg1348
-
Ellegren H. Microsatellites: simple sequences with complex evolution. Nat Rev Genet 2004;5:435-45. (Pubitemid 38915410)
-
(2004)
Nature Reviews Genetics
, vol.5
, Issue.6
, pp. 435-445
-
-
Ellegren, H.1
-
2
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen LA, Peltomäki P, Leach FS, Sistonen P, Pylkkänen L, Mecklin JP, et al. Clues to the pathogenesis of familial colorectal cancer. Science 1993;260:812-6. (Pubitemid 23167611)
-
(1993)
Science
, vol.260
, Issue.5109
, pp. 812-816
-
-
Aaltonen, L.A.1
Peltomaki, P.2
Leach, F.S.3
Sistonen, P.4
Pylkkanen, L.5
Mecklin, J.-P.6
Jarvinen, H.7
Powell, S.M.8
Jen, J.9
Hamilton, S.R.10
Petersen, G.M.11
Kinzler, K.W.12
Vogelstein, B.13
De La, C.A.14
-
3
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
DOI 10.1038/363558a0
-
Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993;363:558-61. (Pubitemid 23186645)
-
(1993)
Nature
, vol.363
, Issue.6429
, pp. 558-561
-
-
Ionov, Y.1
Peinado, M.A.2
Malkhosyan, S.3
Shibata, D.4
Perucho, M.5
-
4
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993;260:816-9. (Pubitemid 23167612)
-
(1993)
Science
, vol.260
, Issue.5109
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
5
-
-
0036144385
-
Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait
-
Halford S, Sasieni P, Rowan A, Wasan H, Bodmer W, Talbot I, et al. Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait. Cancer Res 2002;62:53-7. (Pubitemid 34073985)
-
(2002)
Cancer Research
, vol.62
, Issue.1
, pp. 53-57
-
-
Halford, S.1
Sasieni, P.2
Rowan, A.3
Wasan, H.4
Bodmer, W.5
Talbot, I.6
Hawkins, N.7
Ward, R.8
Tomlinson, I.9
-
6
-
-
0032534069
-
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
-
Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58: 5248-57.
-
(1998)
Cancer Res
, vol.58
, pp. 5248-5257
-
-
Boland, C.R.1
Thibodeau, S.N.2
Hamilton, S.R.3
Sidransky, D.4
Eshleman, J.R.5
Burt, R.W.6
-
7
-
-
10744233937
-
Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability
-
Umar A, Boland CR, Terdiman JP, Syngal S, de la Chapelle A, Rüschoff J, et al. Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 2004;96:261-8. (Pubitemid 38256271)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.4
, pp. 261-268
-
-
Umar, A.1
Boland, C.R.2
Terdiman, J.P.3
Syngal, S.4
De La, C.A.5
Ruschoff, J.6
Fishel, R.7
Lindor, N.M.8
Burgart, L.J.9
Hamelin, R.10
Hamilton, S.R.11
Hiatt, R.A.12
Jass, J.13
Lindblom, A.14
Lynch, H.T.15
Peltomaki, P.16
Ramsey, S.D.17
Rodriguez-Bigas, M.A.18
Vasen, H.F.A.19
Hawk, E.T.20
Barrett, J.C.21
Freedman, A.N.22
Srivastava, S.23
more..
-
8
-
-
0037381250
-
The clinical importance and prognostic implications of microsatellite instability in sporadic cancer
-
DOI 10.1053/ejso.2002.1399
-
Lawes DA, SenGupta S, Boulos PB. The clinical importance and prognostic implications of microsatellite instability in sporadic cancer. Eur J Surg Oncol 2003;29:201-12. (Pubitemid 36395552)
-
(2003)
European Journal of Surgical Oncology
, vol.29
, Issue.3
, pp. 201-212
-
-
Lawes, D.A.1
SenGupta, S.2
Boulos, P.B.3
-
9
-
-
0032584384
-
Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSbeta
-
DOI 10.1074/jbc.273.31.19895
-
Genschel J, Littman SJ, Drummond JT, Modrich P. Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha. J Biol Chem 1998;273: 19895-901. (Pubitemid 28367056)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.31
, pp. 19895-19901
-
-
Genschel, J.1
Littman, S.J.2
Drummond, J.T.3
Modrich, P.4
-
10
-
-
0029659046
-
hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA
-
DOI 10.1016/S0960-9822(02)70685-4
-
Palombo F, Iaccarino I, Nakajima E, Ikejima M, Shimada T, Jiricny J. hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/ deletion loops in DNA. Curr Biol 1996;6:1181-4. (Pubitemid 26368752)
-
(1996)
Current Biology
, vol.6
, Issue.9
, pp. 1181-1184
-
-
Palombo, F.1
Iaccarino, I.2
Nakajima, E.3
Ikejima, M.4
Shimada, T.5
Jiricny, J.6
-
11
-
-
0033527450
-
Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1
-
Räschle M, Marra G, Nyström-Lahti M, Schär P, Jiricny J. Identification of hMutLbeta, a heterodimer of hMLH1 and hPMS1. J Biol Chem 1999;274:32368-75.
-
(1999)
J Biol Chem
, vol.274
, pp. 32368-32375
-
-
Räschle, M.1
Marra, G.2
Nyström-Lahti, M.3
Schär, P.4
Jiricny, J.5
-
12
-
-
28244472115
-
Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair
-
DOI 10.1158/0008-5472.CAN-05-2528
-
Cannavo E, Marra G, Sabates-Bellver J, Menigatti M, Lipkin SM, Fischer F, et al. Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair. Cancer Res 2005;65: 10759-66. (Pubitemid 41713344)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 10759-10766
-
-
Cannavo, E.1
Marra, G.2
Sabates-Bellver, J.3
Menigatti, M.4
Lipkin, S.M.5
Fischer, F.6
Cejka, P.7
Jiricny, J.8
-
13
-
-
24144463165
-
Lynch syndrome genes
-
DOI 10.1007/s10689-004-7993-0
-
Peltomäki P. Lynch syndrome genes. Fam Cancer 2005;4:227-32. (Pubitemid 41242191)
-
(2005)
Familial Cancer
, vol.4
, Issue.3
, pp. 227-232
-
-
Peltomaki, P.1
-
14
-
-
33746189409
-
Endonucleolytic Function of MutLbeta in Human Mismatch Repair
-
DOI 10.1016/j.cell.2006.05.039, PII S0092867406008129
-
Kadyrov FA, Dzantiev L, Constantin N, Modrich P. Endonucleolytic function of MutLalpha in human mismatch repair. Cell 2006;126: 297-308. (Pubitemid 44092957)
-
(2006)
Cell
, vol.126
, Issue.2
, pp. 297-308
-
-
Kadyrov, F.A.1
Dzantiev, L.2
Constantin, N.3
Modrich, P.4
-
15
-
-
0037066720
-
Humanexonuclease I is required for 5¢ and 3¢ mismatch repair
-
Genschel J, Bazemore LR, Modrich P.Humanexonuclease I is required for 5¢ and 3¢ mismatch repair. J Biol Chem 2002;277:13302-11.
-
(2002)
J Biol Chem
, vol.277
, pp. 13302-13311
-
-
Genschel, J.1
Bazemore, L.R.2
Modrich, P.3
-
16
-
-
0037364995
-
Inactivation of exonuclease I in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility
-
DOI 10.1101/gad.1060603
-
Wei K, Clark AB, Wong E, Kane MF, Mazur DJ, Parris T, et al. Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. Genes Dev 2003;17:603-14. (Pubitemid 36307545)
-
(2003)
Genes and Development
, vol.17
, Issue.5
, pp. 603-614
-
-
Wei, K.1
Clark, A.B.2
Wong, E.3
Kane, M.F.4
Mazur, D.J.5
Parris, T.6
Kolas, N.K.7
Russell, R.8
Hou Jr., H.9
Kneitz, B.10
Yang, G.11
Kunkel, T.A.12
Kolodner, R.D.13
Cohen, P.E.14
Edelmann, W.15
-
17
-
-
19444379003
-
hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair
-
DOI 10.1038/sj.embor.7400392
-
Vo AT, Zhu F, Wu X, Yuan F, Gao Y, Gu L, et al. hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair. EMBO Rep 2005;6:438-44. (Pubitemid 40767077)
-
(2005)
EMBO Reports
, vol.6
, Issue.5
, pp. 438-444
-
-
Vo, A.T.1
Zhu, F.2
Wu, X.3
Yuan, F.4
Gao, Y.5
Gu, L.6
Li, G.-M.7
Lee, T.-H.8
Her, C.9
-
18
-
-
18344395671
-
Human MRE11 is inactivated in mismatch repair-deficient cancers
-
DOI 10.1093/embo-reports/kvf044
-
Giannini G, Ristori E, Cerignoli F, Rinaldi C, Zani M, Viel A, et al. Human MRE11 is inactivated in mismatch repair-deficient cancers. EMBO Rep 2002;3:248-54. (Pubitemid 34269518)
-
(2002)
EMBO Reports
, vol.3
, Issue.3
, pp. 248-254
-
-
Giannini, G.1
Ristori, E.2
Cerignoli, F.3
Rinaldi, C.4
Zani, M.5
Viel, A.6
Ottini, L.7
Crescenzi, M.8
Martinotti, S.9
Bignami, M.10
Frati, L.11
Screpanti, I.12
Gulino, A.13
-
19
-
-
10344225054
-
MRE11 expression is impaired in gastric cancer with microsatellite instability
-
DOI 10.1093/carcin/bgh257
-
Ottini L, Falchetti M, Saieva C, De Marco M, Masala G, Zanna I, et al. MRE11 expression is impaired in gastric cancer with microsatellite instability. Carcinogenesis 2004;25:2337-43. (Pubitemid 39625173)
-
(2004)
Carcinogenesis
, vol.25
, Issue.12
, pp. 2337-2343
-
-
Ottini, L.1
Falchetti, M.2
Saieva, C.3
De Marco, M.4
Masala, G.5
Zanna, I.6
Paglierani, M.7
Giannini, G.8
Gulino, A.9
Nesi, G.10
Costantini, R.M.11
Palli, D.12
-
20
-
-
3142658762
-
Hypersensitivity of tumor cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin
-
DOI 10.1158/0008-5472.CAN-04-0975
-
Li HR, Shagisultanova EI, Yamashita K, Piao Z, Perucho M, Malkhosyan SR. Hypersensitivity of tumor cell lines with microsatellite instability to DNA double strand break producing chemotherapeutic agent bleomycin. Cancer Res 2004;64:4760-7. (Pubitemid 38924519)
-
(2004)
Cancer Research
, vol.64
, Issue.14
, pp. 4760-4767
-
-
Li, H.-R.1
Shagisultanova, E.I.2
Yamashita, K.3
Piao, Z.4
Perucho, M.5
Malkhosyan, S.R.6
-
21
-
-
2342467382
-
Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability
-
DOI 10.1038/sj.onc.1207409
-
Giannini G, Rinaldi C, Ristori E, Ambrosini MI, Cerignoli F, Viel A, et al. Mutations of an intronic repeat induce impaired MRE11 expression in primary human cancer with microsatellite instability. Oncogene 2004;23:2640-7. (Pubitemid 38586317)
-
(2004)
Oncogene
, vol.23
, Issue.15
, pp. 2640-2647
-
-
Giannini, G.1
Rinaldi, C.2
Ristori, E.3
Ambrosini, M.I.4
Cerignoli, F.5
Viel, A.6
Bidoli, E.7
Berni, S.8
D'Amati, G.9
Scambia, G.10
Frati, L.11
Screpanti, I.12
Gulino, A.13
-
22
-
-
33645510806
-
Microsatellite instability and mutation analysis of candidate genes in urothelial cell carcinomas of upper urinary tract
-
Mongiat-Artus P, Miquel C, Van der Aa M, Buhard O, Hamelin R, Soliman H, et al. Microsatellite instability and mutation analysis of candidate genes in urothelial cell carcinomas of upper urinary tract. Oncogene 2006;25:2113-8.
-
(2006)
Oncogene
, vol.25
, pp. 2113-2118
-
-
Mongiat-Artus, P.1
Miquel, C.2
Van Der Aa, M.3
Buhard, O.4
Hamelin, R.5
Soliman, H.6
-
23
-
-
33646009986
-
Impairment of double-strand breaks repair and aberrant splicing of ATM and MRE11 in leukemia-lymphoma cell lines with microsatellite instability
-
Ham MF, Takakuwa T, Luo WJ, Liu A, Horii A, Aozasa K. Impairment of double-strand breaks repair and aberrant splicing of ATM and MRE11 in leukemia-lymphoma cell lines with microsatellite instability. Cancer Sci 2006;97:226-34.
-
(2006)
Cancer Sci
, vol.97
, pp. 226-234
-
-
Ham, M.F.1
Takakuwa, T.2
Luo, W.J.3
Liu, A.4
Horii, A.5
Aozasa, K.6
-
24
-
-
34548155765
-
The MRE11/RAD50/NBS1 complex destabilization in Lynch-syndrome patients
-
DOI 10.1038/sj.ejhg.5201858, PII 5201858
-
Alemayehu A, Fridrichova I. The MRE11/RAD50/NBS1 complex destabilization in Lynch-syndrome patients. Eur J Hum Genet 2007;15:922-9. (Pubitemid 47308467)
-
(2007)
European Journal of Human Genetics
, vol.15
, Issue.9
, pp. 922-929
-
-
Alemayehu, A.1
Fridrichova, I.2
-
25
-
-
35148887112
-
Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability
-
Miquel C, Jacob S, Grandjouan S, Aimé A, Viguier J, Sabourin JC, et al. Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability. Oncogene 2007;26:5919-26.
-
(2007)
Oncogene
, vol.26
, pp. 5919-5926
-
-
Miquel, C.1
Jacob, S.2
Grandjouan, S.3
Aimé, A.4
Viguier, J.5
Sabourin, J.C.6
-
26
-
-
49349113150
-
Differential cancer predisposition in Lynch syndrome: Insights from molecular analysis of brain and urinary tract tumors
-
Gylling AH, Nieminen TT, Abdel-Rahman WM, Nuorva K, Juhola M, Joensuu EI, et al. Differential cancer predisposition in Lynch syndrome: insights from molecular analysis of brain and urinary tract tumors. Carcinogenesis 2008;29:1351-9.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1351-1359
-
-
Gylling, A.H.1
Nieminen, T.T.2
Abdel-Rahman, W.M.3
Nuorva, K.4
Juhola, M.5
Joensuu, E.I.6
-
27
-
-
59149095034
-
Genome-wide expression profile of sporadic gastric cancers with microsatellite instability
-
D'Errico M, de Rinaldis E, Blasi MF, Viti V, Falchetti M, Calcagnile A, et al. Genome-wide expression profile of sporadic gastric cancers with microsatellite instability. Eur J Cancer 2009;45:461-9.
-
(2009)
Eur J Cancer
, vol.45
, pp. 461-469
-
-
D'Errico, M.1
De Rinaldis, E.2
Blasi, M.F.3
Viti, V.4
Falchetti, M.5
Calcagnile, A.6
-
28
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J. BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 2000;14:927-39. (Pubitemid 30253002)
-
(2000)
Genes and Development
, vol.14
, Issue.8
, pp. 927-939
-
-
Wang, Y.1
Cortez, D.2
Yazdi, P.3
Neff, N.4
Elledge, S.J.5
Qin, J.6
-
29
-
-
0037019607
-
Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1
-
Her C, Vo AT, Wu X. Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1. DNA Repair (Amst) 2002;1:719-29.
-
(2002)
DNA Repair (Amst)
, vol.1
, pp. 719-729
-
-
Her, C.1
Vo, A.T.2
Wu, X.3
-
30
-
-
33845214070
-
2 arrest and cytotoxicity
-
DOI 10.1158/1535-7163.MCT-06-0183
-
Mirzoeva OK, Kawaguchi T, Pieper RO. The Mre11/Rad50/Nbs1 complex interacts with the mismatch repair system and contributes to temozolomide-induced G2 arrest and cytotoxicity. Mol Cancer Ther 2006;5:2757-66. (Pubitemid 44849002)
-
(2006)
Molecular Cancer Therapeutics
, vol.5
, Issue.11
, pp. 2757-2766
-
-
Mirzoeva, O.K.1
Kawaguchi, T.2
Pieper, R.O.3
-
31
-
-
42249086268
-
The interplay between hMLH1 and hMRE11: Role in MMR and the effect of hMLH1 mutations
-
Zhao N, Zhu F, Yuan F, Haick AK, Fukushige S, Gu L, et al. The interplay between hMLH1 and hMRE11: role in MMR and the effect of hMLH1 mutations. Biochem Biophys Res Commun 2008;370: 338-43.
-
(2008)
Biochem Biophys Res Commun
, vol.370
, pp. 338-343
-
-
Zhao, N.1
Zhu, F.2
Yuan, F.3
Haick, A.K.4
Fukushige, S.5
Gu, L.6
-
32
-
-
0142136826
-
Requirement of the MRN complex for ATM activation by DNA damage
-
DOI 10.1093/emboj/cdg541
-
Uziel T, Lerenthal Y, Moyal L, Andegeko Y, Mittelman L, Shiloh Y. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J 2003;22:5612-21. (Pubitemid 37279970)
-
(2003)
EMBO Journal
, vol.22
, Issue.20
, pp. 5612-5621
-
-
Uziel, T.1
Lerenthal, Y.2
Moyal, L.3
Andegeko, Y.4
Mittelman, L.5
Shiloh, Y.6
-
33
-
-
0037881803
-
2/M arrest requires a full complement of the mismatch repair protein hMLH1
-
DOI 10.1093/emboj/cdg216
-
Cejka P, Stojic L, Mojas N, Russell AM, Heinimann K, Cannavó E, et al. Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1. EMBO J 2003;22:2245-54. (Pubitemid 36565547)
-
(2003)
EMBO Journal
, vol.22
, Issue.9
, pp. 2245-2254
-
-
Cejka, P.1
Stojic, L.2
Mojas, N.3
Russell, A.M.4
Heinimann, K.5
Cannavo, E.6
Di, P.M.7
Marra, G.8
Jiricny, J.9
-
34
-
-
68249138694
-
Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells
-
Rass E, Grabarz A, Plo I, Gautier J, Bertrand P, Lopez BS. Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells. Nat Struct Mol Biol 2009;16:819-24.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 819-824
-
-
Rass, E.1
Grabarz, A.2
Plo, I.3
Gautier, J.4
Bertrand, P.5
Lopez, B.S.6
-
35
-
-
68249146431
-
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
-
Xie A, Kwok A, Scully R. Role of mammalian Mre11 in classical and alternative nonhomologous end joining. Nat Struct Mol Biol 2009;16: 814-8.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 814-818
-
-
Xie, A.1
Kwok, A.2
Scully, R.3
-
36
-
-
58149145579
-
Human MutL-complexes monitor homologous recombination independently of mismatch repair
-
Siehler SY, Schrauder M, Gerischer U, Cantor S, Marra G, Wiesmüller L. Human MutL-complexes monitor homologous recombination independently of mismatch repair. DNA Repair (Amst) 2009;8: 242-52.
-
(2009)
DNA Repair (Amst)
, vol.8
, pp. 242-252
-
-
Siehler, S.Y.1
Schrauder, M.2
Gerischer, U.3
Cantor, S.4
Marra, G.5
Wiesmüller, L.6
-
38
-
-
46449117172
-
The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: From bench to bedside
-
Boland CR, Koi M, Chang DK, Carethers JM. The biochemical basis of microsatellite instability and abnormal immunohistochemistry and clinical behavior in Lynch syndrome: from bench to bedside. Fam Cancer 2008;7:41-52.
-
(2008)
Fam Cancer
, vol.7
, pp. 41-52
-
-
Boland, C.R.1
Koi, M.2
Chang, D.K.3
Carethers, J.M.4
-
39
-
-
33644601309
-
Does tumorigenesis select for or against mutations of the DNA repair-associated genes BRCA2 and MRE11?: Considerations from somatic mutations in microsatellite unstable (MSI) gastrointestinal cancers
-
van der Heijden MS, Brody JR, Elghalbzouri-Maghrani E, Zdzienicka MZ, Kern SE. Does tumorigenesis select for or against mutations of the DNA repair-associated genes BRCA2 and MRE11?: considerations from somatic mutations in microsatellite unstable (MSI) gastrointestinal cancers. BMC Genet 2006;7:3.
-
(2006)
BMC Genet
, vol.7
, pp. 3
-
-
Van Der Heijden, M.S.1
Brody, J.R.2
Elghalbzouri-Maghrani, E.3
Zdzienicka, M.Z.4
Kern, S.E.5
-
40
-
-
0035135548
-
Frameshift mutations at coding mononucleotide repeats of the hRAD50 gene in gastrointestinal carcinomas with Microsatellite instability
-
Kim NG, Choi YR, Baek MJ, Kim YH, Kang H, Kim NK, et al. Frameshift mutations at coding mononucleotide repeats of the hRAD50 gene in gastrointestinal carcinomas with microsatellite instability. Cancer Res 2001;61:36-8. (Pubitemid 32095695)
-
(2001)
Cancer Research
, vol.61
, Issue.1
, pp. 36-38
-
-
Kim, N.-G.1
Yon, R.C.2
Myung, J.B.3
Yun, H.K.4
Kang, H.5
Nam, K.K.6
Jin, S.M.7
Kim, H.8
-
41
-
-
53049108631
-
Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11
-
Rodriguez R, Hansen LT, Phear G, Scorah J, Spang-Thomsen M, Cox A, et al. Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11. Clin Cancer Res 2008;14:5476-83.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5476-5483
-
-
Rodriguez, R.1
Hansen, L.T.2
Phear, G.3
Scorah, J.4
Spang-Thomsen, M.5
Cox, A.6
-
42
-
-
0037226818
-
DNA replication-dependent nuclear dynamics of the Mre11 complex
-
Mirzoeva OK, Petrini JH. DNA replication-dependent nuclear dynamics of the Mre11 complex. Mol Cancer Res 2003;1:207-18. (Pubitemid 36330202)
-
(2003)
Molecular Cancer Research
, vol.1
, Issue.3
, pp. 207-218
-
-
Mirzoeva, O.K.1
Petrini, J.H.J.2
-
43
-
-
52949109260
-
Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation
-
Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, et al. Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation. Cell 2008;135:85-96.
-
(2008)
Cell
, vol.135
, pp. 85-96
-
-
Buis, J.1
Wu, Y.2
Deng, Y.3
Leddon, J.4
Westfield, G.5
Eckersdorff, M.6
-
44
-
-
2442659384
-
Telomeric recombination in mismatch repair deficient human colon cancer cells after telomerase inhibition
-
DOI 10.1158/0008-5472.CAN-04-0323
-
Bechter OE, Zou Y, Walker W, Wright WE, Shay JW. Telomeric recombination in mismatch repair deficient human colon cancer cells after telomerase inhibition. Cancer Res 2004;64:3444-51. (Pubitemid 38657916)
-
(2004)
Cancer Research
, vol.64
, Issue.10
, pp. 3444-3451
-
-
Bechter, O.E.1
Zou, Y.2
Walker, W.3
Wright, W.E.4
Shay, J.W.5
-
45
-
-
0342561644
-
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
-
Zhu XD, K€uster B, Mann M, Petrini JH, de Lange T. Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat Genet 2000;25:347-52.
-
(2000)
Nat Genet
, vol.25
, pp. 347-352
-
-
Zhu, X.D.1
Keuster, B.2
Mann, M.3
Petrini, J.H.4
De Lange, T.5
-
46
-
-
68949149732
-
Multiple roles for MRE11 at uncapped telomeres
-
Deng Y, Guo X, Ferguson DO, Chang S. Multiple roles for MRE11 at uncapped telomeres. Nature 2009;460:914-8.
-
(2009)
Nature
, vol.460
, pp. 914-918
-
-
Deng, Y.1
Guo, X.2
Ferguson, D.O.3
Chang, S.4
-
47
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn EH. Switching and signaling at the telomere. Cell 2001;106:661-73.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
48
-
-
24944460598
-
Shelterin: The protein complex that shapes and safeguards human telomeres
-
de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev 2005;19:2100-10.
-
(2005)
Genes Dev
, vol.19
, pp. 2100-2110
-
-
De Lange, T.1
-
49
-
-
2442689011
-
Telomere instability detected in sporadic colon cancers, some showing mutations in a mismatch repair gene
-
DOI 10.1038/sj.onc.1207477
-
Pickett HA, Baird DM, Hoff-Olsen P, Meling GI, Rognum TO, Shaw J, et al. Telomere instability detected in sporadic colon cancers, some showing mutations in a mismatch repair gene. Oncogene 2004;23: 3434-43. (Pubitemid 38669833)
-
(2004)
Oncogene
, vol.23
, Issue.19
, pp. 3434-3443
-
-
Pickett, H.A.1
Baird, D.M.2
Hoff-Olsen, P.3
Meling, G.I.4
Rognum, T.O.5
Shaw, J.6
West, K.P.7
Royle, N.J.8
-
50
-
-
0033788136
-
Relationship between microsatellite instability and telomere shortening in colorectal cancer
-
Takagi S, Kinouchi Y, Hiwatashi N, Nagashima F, Chida M, Takahashi S, et al. Relationship between microsatellite instability and telomere shortening in colorectal cancer. Dis Colon Rectum 2000;43[Suppl]: S12-7.
-
(2000)
Dis Colon Rectum
, vol.43
, Issue.SUPPL.
-
-
Takagi, S.1
Kinouchi, Y.2
Hiwatashi, N.3
Nagashima, F.4
Chida, M.5
Takahashi, S.6
-
51
-
-
79960755430
-
Deficiency in DNA mismatch repair increases the rate of telomere-shortening in normal human cells
-
Mendez-Bermudez A, Royle NJ. Deficiency in DNA mismatch repair increases the rate of telomere-shortening in normal human cells. Hum Mutat 2011;32:939-46.
-
(2011)
Hum Mutat
, vol.32
, pp. 939-946
-
-
Mendez-Bermudez, A.1
Royle, N.J.2
-
52
-
-
59049097927
-
MSH2 deficiency abolishes the anticancer and pro-aging activity of short telomeres
-
Martinez P, Siegl-Cachedenier I, Flores JM, Blasco MA. MSH2 deficiency abolishes the anticancer and pro-aging activity of short telomeres. Aging Cell 2009;8:2-17.
-
(2009)
Aging Cell
, vol.8
, pp. 2-17
-
-
Martinez, P.1
Siegl-Cachedenier, I.2
Flores, J.M.3
Blasco, M.A.4
-
53
-
-
70350692143
-
Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline
-
Mendez-Bermudez A, Hills M, Pickett HA, Phan AT, Mergny JL, Riou JF, et al. Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline. Nucleic Acids Res 2009;37:6225-38.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 6225-6238
-
-
Mendez-Bermudez, A.1
Hills, M.2
Pickett, H.A.3
Phan, A.T.4
Mergny, J.L.5
Riou, J.F.6
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