Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 46, 2011, Pages 18696-18701

  Yang, Ri Yao ^a   Yu, Lan ^a   Graham, James L ^b   Hsu, Daniel K ^a   Lloyd, K C Kent ^b   Havel, Peter J ^b   Liu, Fu Tong ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

Diabetes; Energy metabolism; Obesity

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FAT DROPLET; GALECTIN; PHOSPHODIESTERASE; TRIACYLGLYCEROL;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL ORGANELLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRACELLULAR SPACE; LIPID METABOLISM; LIPOLYSIS; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

3T3 CELLS; ADIPOCYTES; ANIMALS; CELL CYCLE PROTEINS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GALECTINS; INSULIN; INSULIN RESISTANCE; LECTINS; LIPID METABOLISM; LIPOLYSIS; MICE; MICE, TRANSGENIC; PHOSPHORIC DIESTER HYDROLASES; SIGNAL TRANSDUCTION;

ANIMALIA; MUS;

EID: 81755163611     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1109065108     Document Type: Article

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