메뉴 건너뛰기




Volumn 80, Issue 6, 2011, Pages 955-958

How can 1 + 1 = 3? β 2-adrenergic and glucocorticoid receptor agonist synergism in obstructive airway diseases

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR AGONIST; UNCLASSIFIED DRUG;

EID: 81555195477     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.075481     Document Type: Review
Times cited : (9)

References (40)
  • 1
    • 49449089908 scopus 로고    scopus 로고
    • Molecular mechanisms of corticosteroid resistance
    • Adcock IM and Barnes PJ (2008) Molecular mechanisms of corticosteroid resistance. Chest 134:394-401.
    • (2008) Chest , vol.134 , pp. 394-401
    • Adcock, I.M.1    Barnes, P.J.2
  • 3
    • 33644784718 scopus 로고    scopus 로고
    • Corticosteroids: The drugs to beat
    • Barnes PJ (2006a) Corticosteroids: the drugs to beat. Eur J Pharmacol 533:2-14.
    • (2006) Eur J Pharmacol , vol.533 , pp. 2-14
    • Barnes, P.J.1
  • 4
    • 33744477341 scopus 로고    scopus 로고
    • How corticosteroids control inflammation: Quintiles Prize Lecture 2005
    • Barnes PJ (2006b) How corticosteroids control inflammation: Quintiles Prize Lecture 2005. Br J Pharmacol 148:245-254.
    • (2006) Br J Pharmacol , vol.148 , pp. 245-254
    • Barnes, P.J.1
  • 5
    • 51249109929 scopus 로고    scopus 로고
    • Relative corticoid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma
    • Bhavsar P, Hew M, Khorasani N, Torrego A, Barnes PJ, Adcock I, and Chung KF (2008) Relative corticoid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma. Thorax 63:784-790.
    • (2008) Thorax , vol.63 , pp. 784-790
    • Bhavsar, P.1    Hew, M.2    Khorasani, N.3    Torrego, A.4    Barnes, P.J.5    Adcock, I.6    Chung, K.F.7
  • 6
    • 70350120599 scopus 로고    scopus 로고
    • Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting β-agonists
    • Black JL, Oliver BG, and Roth M (2009) Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting β-agonists. Chest 136:1095-1100.
    • (2009) Chest , vol.136 , pp. 1095-1100
    • Black, J.L.1    Oliver, B.G.2    Roth, M.3
  • 10
    • 0022525666 scopus 로고
    • Human β-adrenoceptors: Relation of myocardial and lymphocyte β-adrenoceptor density
    • Brodde OE, Kretsch R, Ikezono K, Zerkowski HR, and Reidemeister JC (1986) Human β-adrenoceptors: relation of myocardial and lymphocyte β-adrenoceptor density. Science 231:1584-1585. (Pubitemid 16050732)
    • (1986) Science , vol.231 , Issue.4745 , pp. 1584-1585
    • Brodde, O.-E.1    Kretsch, R.2    Ikezono, K.3
  • 12
    • 0025316096 scopus 로고
    • Separation of the structural requirements for agonist-promoted activation and sequestration of the β-adrenergic receptor
    • Cheung AH, Dixon RA, Hill WS, Sigal IS, and Strader CD (1990) Separation of the structural requirements for agonist-promoted activation and sequestration of the β-adrenergic receptor. Mol Pharmacol 37:775-779. (Pubitemid 20219883)
    • (1990) Molecular Pharmacology , vol.37 , Issue.6 , pp. 775-779
    • Cheung, A.H.1    Dixon, R.A.F.2    Hill, W.S.3    Sigal, I.S.4    Strader, C.D.5
  • 13
    • 54449097818 scopus 로고    scopus 로고
    • Role of dual specificity phosphatases in biological responses to glucocorticoids
    • Clark AR, Martins JR, and Tchen CR (2008) Role of dual specificity phosphatases in biological responses to glucocorticoids. J Biol Chem 283:25765-25769.
    • (2008) J Biol Chem , vol.283 , pp. 25765-25769
    • Clark, A.R.1    Martins, J.R.2    Tchen, C.R.3
  • 17
    • 40949165358 scopus 로고    scopus 로고
    • 2-adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids
    • DOI 10.1038/sj.bjp.0707627, PII 0707627
    • Giembycz MA, Kaur M, Leigh R, and Newton R (2008) A holy grail of asthma management: toward understanding how long-acting β2-adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids. Br J Pharmacol 153:1090-1104. (Pubitemid 351415494)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.6 , pp. 1090-1104
    • Giembycz, M.A.1    Kaur, M.2    Leigh, R.3    Newton, R.4
  • 18
    • 33750742437 scopus 로고    scopus 로고
    • 2-adrenoceptor signalling in the airways
    • 2-adrenoceptor signalling in the airways. Eur Respir J 27:1286-1306.
    • (2006) Eur Respir J , vol.27 , pp. 1286-1306
    • Giembycz, M.A.1    Newton, R.2
  • 20
    • 75649097760 scopus 로고    scopus 로고
    • The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function
    • Grandoch M, Roscioni SS, and Schmidt M (2010) The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function. Br J Pharmacol 159:265-284.
    • (2010) Br J Pharmacol , vol.159 , pp. 265-284
    • Grandoch, M.1    Roscioni, S.S.2    Schmidt, M.3
  • 21
    • 0012878853 scopus 로고
    • Regulation of β-adrenergic receptors by 'permissive' hormones: Glucocorticoids increase steady-state levels of receptor mRNA
    • DOI 10.1073/pnas.85.22.8415
    • Hadcock JR and Malbon CC (1988) Regulation of β-adrenergic receptors by "permissive"hormones: glucocorticoids increase steady-state levels of receptor mRNA. Proc Natl Acad Sci USA 85:8415-8419. (Pubitemid 19024985)
    • (1988) Proceedings of the National Academy of Sciences of the United States of America , vol.85 , Issue.22 , pp. 8415-8419
    • Hadcock, J.R.1    Malbon, C.C.2
  • 22
    • 0028568232 scopus 로고
    • Dexamethasone partially protects the myometrium against β-adrenergic agonist-induced desensitization in vivo in the rat
    • Herman-Gnjidic Z, MacLusky NJ, and Lye SJ (1994) Dexamethasone partially protects the myometrium against β-adrenergic agonist-induced desensitization in vivo in the rat. Am J Obstet Gynecol 171:1651-1659.
    • (1994) Am J Obstet Gynecol , vol.171 , pp. 1651-1659
    • Herman-Gnjidic, Z.1    MacLusky, N.J.2    Lye, S.J.3
  • 23
    • 0036231010 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma
    • DOI 10.1067/mai.2002.122465
    • Irusen E, Matthews JG, Takahashi A, Barnes PJ, Chung KF, and Adcock IM (2002) p38 mitogen-activated protein kinase-incued glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma. J Allergy Clin Immunol 109:649-657. (Pubitemid 34327193)
    • (2002) Journal of Allergy and Clinical Immunology , vol.109 , Issue.4 , pp. 649-657
    • Irusen, E.1    Matthews, J.G.2    Takahashi, A.3    Barnes, P.J.4    Chung, K.F.5    Adcock, I.M.6
  • 24
    • 29544449036 scopus 로고    scopus 로고
    • 2-adrenergic receptor function, response, and regulation
    • 2-adrenergic receptor function, response, and regulation. J Allergy Clin Immunol 117:18-24.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 18-24
    • Johnson, M.1
  • 25
    • 37349117437 scopus 로고    scopus 로고
    • 2-adrenoceptor agonists synergistically enhance glucocorticoid-dependent transcription in human airway epithelial and smooth muscle cells
    • 2-adrenoceptor agonists synergistically enhance glucocorticoid-dependent transcription in human airway epithelial and smooth muscle cells. Mol Pharmacol 73:203-214.
    • (2008) Mol Pharmacol , vol.73 , pp. 203-214
    • Kaur, M.1    Chivers, J.E.2    Giembycz, M.A.3    Newton, R.4
  • 27
    • 0032563291 scopus 로고    scopus 로고
    • G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization
    • Lefkowitz RJ (1998) G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization. J Biol Chem 273:18677-18680.
    • (1998) J Biol Chem , vol.273 , pp. 18677-18680
    • Lefkowitz, R.J.1
  • 28
    • 77956644353 scopus 로고    scopus 로고
    • Regulation of T cells in airway disease by beta-agonist
    • Loza MJ and Penn RB (2010) Regulation of T cells in airway disease by beta-agonist. Front Biosci (Schol Ed) 2:969-979.
    • (2010) Front Biosci (Schol Ed) , vol.2 , pp. 969-979
    • Loza, M.J.1    Penn, R.B.2
  • 35
    • 47149117849 scopus 로고    scopus 로고
    • Embracing emerging paradigms of G protein-coupled receptor agonism and signaling to address airway smooth muscle pathobiology in asthma
    • Penn RB (2008) Embracing emerging paradigms of G protein-coupled receptor agonism and signaling to address airway smooth muscle pathobiology in asthma. Naunyn Schmiedebergs Arch Pharmacol 378:149-169.
    • (2008) Naunyn Schmiedebergs Arch Pharmacol , vol.378 , pp. 149-169
    • Penn, R.B.1
  • 40
    • 2442682766 scopus 로고    scopus 로고
    • The pro-apoptotic protein Bim is a convergence point for cAMP/protein kinase A- and glucocorticoid-promoted apoptosis of lymphoid cells
    • DOI 10.1074/jbc.M310643200
    • Zhang L and Insel PA (2004) The pro-apoptotic protein Bim is a convergence point for cAMP/protein kinase A- and glucocorticoid-promoted apoptosis of lymphoid cells. J Biol Chem 279:20858-20865. (Pubitemid 38656482)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.20 , pp. 20858-20865
    • Zhang, L.1    Insel, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.