-
1
-
-
49449089908
-
Molecular mechanisms of corticosteroid resistance
-
Adcock IM and Barnes PJ (2008) Molecular mechanisms of corticosteroid resistance. Chest 134:394-401.
-
(2008)
Chest
, vol.134
, pp. 394-401
-
-
Adcock, I.M.1
Barnes, P.J.2
-
3
-
-
33644784718
-
Corticosteroids: The drugs to beat
-
Barnes PJ (2006a) Corticosteroids: the drugs to beat. Eur J Pharmacol 533:2-14.
-
(2006)
Eur J Pharmacol
, vol.533
, pp. 2-14
-
-
Barnes, P.J.1
-
4
-
-
33744477341
-
How corticosteroids control inflammation: Quintiles Prize Lecture 2005
-
Barnes PJ (2006b) How corticosteroids control inflammation: Quintiles Prize Lecture 2005. Br J Pharmacol 148:245-254.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 245-254
-
-
Barnes, P.J.1
-
5
-
-
51249109929
-
Relative corticoid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma
-
Bhavsar P, Hew M, Khorasani N, Torrego A, Barnes PJ, Adcock I, and Chung KF (2008) Relative corticoid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma. Thorax 63:784-790.
-
(2008)
Thorax
, vol.63
, pp. 784-790
-
-
Bhavsar, P.1
Hew, M.2
Khorasani, N.3
Torrego, A.4
Barnes, P.J.5
Adcock, I.6
Chung, K.F.7
-
6
-
-
70350120599
-
Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting β-agonists
-
Black JL, Oliver BG, and Roth M (2009) Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting β-agonists. Chest 136:1095-1100.
-
(2009)
Chest
, vol.136
, pp. 1095-1100
-
-
Black, J.L.1
Oliver, B.G.2
Roth, M.3
-
7
-
-
38449113726
-
Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: A comparison
-
DOI 10.1183/09031936.00004907
-
Bos IS, Gosens R, Zuidhof AB, Schaafsma D, Halayko AJ, Meurs H, and Zaagsma J (2007) Inhibition of allergen-induced airway remodelling by tiotropium and budesonide: a comparison. Eur Respir J 30:653-661. (Pubitemid 351194824)
-
(2007)
European Respiratory Journal
, vol.30
, Issue.4
, pp. 653-661
-
-
Bos, I.S.T.1
Gosens, R.2
Zuidhof, A.B.3
Schaafsma, D.4
Halayko, A.J.5
Meurs, H.6
Zaagsma, J.7
-
8
-
-
0024461392
-
2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level
-
2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. J Biol Chem 264:16786-16792.
-
(1989)
J Biol Chem
, vol.264
, pp. 16786-16792
-
-
Bouvier, M.1
Collins, S.2
O'Dowd, B.F.3
Campbell, P.T.4
De Blasi, A.5
Kobilka, B.K.6
MacGregor, C.7
Irons, G.P.8
Caron, M.G.9
Lefkowitz, R.J.10
-
10
-
-
0022525666
-
Human β-adrenoceptors: Relation of myocardial and lymphocyte β-adrenoceptor density
-
Brodde OE, Kretsch R, Ikezono K, Zerkowski HR, and Reidemeister JC (1986) Human β-adrenoceptors: relation of myocardial and lymphocyte β-adrenoceptor density. Science 231:1584-1585. (Pubitemid 16050732)
-
(1986)
Science
, vol.231
, Issue.4745
, pp. 1584-1585
-
-
Brodde, O.-E.1
Kretsch, R.2
Ikezono, K.3
-
11
-
-
0024412243
-
β-adrenoceptor regulation in the human heart: Can it be monitored in circulating lymphocytes?
-
Brodde OE, Michel MC, Gordon EP, Sandoval A, Gilbert EM, and Bristow MR (1989) β-Adrenoceptor regulation in the human heart: can it be monitored in circulating lymphocytes? Eur Heart J 10 (Suppl B):2-10. (Pubitemid 19182626)
-
(1989)
European Heart Journal
, vol.10
, Issue.SUPPL. B
, pp. 2-10
-
-
Brodde, O.-E.1
Michel, M.C.2
Gordon, E.P.3
Sandoval, A.4
Gilbert, E.M.5
Bristow, M.R.6
-
12
-
-
0025316096
-
Separation of the structural requirements for agonist-promoted activation and sequestration of the β-adrenergic receptor
-
Cheung AH, Dixon RA, Hill WS, Sigal IS, and Strader CD (1990) Separation of the structural requirements for agonist-promoted activation and sequestration of the β-adrenergic receptor. Mol Pharmacol 37:775-779. (Pubitemid 20219883)
-
(1990)
Molecular Pharmacology
, vol.37
, Issue.6
, pp. 775-779
-
-
Cheung, A.H.1
Dixon, R.A.F.2
Hill, W.S.3
Sigal, I.S.4
Strader, C.D.5
-
13
-
-
54449097818
-
Role of dual specificity phosphatases in biological responses to glucocorticoids
-
Clark AR, Martins JR, and Tchen CR (2008) Role of dual specificity phosphatases in biological responses to glucocorticoids. J Biol Chem 283:25765-25769.
-
(2008)
J Biol Chem
, vol.283
, pp. 25765-25769
-
-
Clark, A.R.1
Martins, J.R.2
Tchen, C.R.3
-
17
-
-
40949165358
-
2-adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids
-
DOI 10.1038/sj.bjp.0707627, PII 0707627
-
Giembycz MA, Kaur M, Leigh R, and Newton R (2008) A holy grail of asthma management: toward understanding how long-acting β2-adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids. Br J Pharmacol 153:1090-1104. (Pubitemid 351415494)
-
(2008)
British Journal of Pharmacology
, vol.153
, Issue.6
, pp. 1090-1104
-
-
Giembycz, M.A.1
Kaur, M.2
Leigh, R.3
Newton, R.4
-
18
-
-
33750742437
-
2-adrenoceptor signalling in the airways
-
2-adrenoceptor signalling in the airways. Eur Respir J 27:1286-1306.
-
(2006)
Eur Respir J
, vol.27
, pp. 1286-1306
-
-
Giembycz, M.A.1
Newton, R.2
-
20
-
-
75649097760
-
The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function
-
Grandoch M, Roscioni SS, and Schmidt M (2010) The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function. Br J Pharmacol 159:265-284.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 265-284
-
-
Grandoch, M.1
Roscioni, S.S.2
Schmidt, M.3
-
21
-
-
0012878853
-
Regulation of β-adrenergic receptors by 'permissive' hormones: Glucocorticoids increase steady-state levels of receptor mRNA
-
DOI 10.1073/pnas.85.22.8415
-
Hadcock JR and Malbon CC (1988) Regulation of β-adrenergic receptors by "permissive"hormones: glucocorticoids increase steady-state levels of receptor mRNA. Proc Natl Acad Sci USA 85:8415-8419. (Pubitemid 19024985)
-
(1988)
Proceedings of the National Academy of Sciences of the United States of America
, vol.85
, Issue.22
, pp. 8415-8419
-
-
Hadcock, J.R.1
Malbon, C.C.2
-
22
-
-
0028568232
-
Dexamethasone partially protects the myometrium against β-adrenergic agonist-induced desensitization in vivo in the rat
-
Herman-Gnjidic Z, MacLusky NJ, and Lye SJ (1994) Dexamethasone partially protects the myometrium against β-adrenergic agonist-induced desensitization in vivo in the rat. Am J Obstet Gynecol 171:1651-1659.
-
(1994)
Am J Obstet Gynecol
, vol.171
, pp. 1651-1659
-
-
Herman-Gnjidic, Z.1
MacLusky, N.J.2
Lye, S.J.3
-
23
-
-
0036231010
-
p38 mitogen-activated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma
-
DOI 10.1067/mai.2002.122465
-
Irusen E, Matthews JG, Takahashi A, Barnes PJ, Chung KF, and Adcock IM (2002) p38 mitogen-activated protein kinase-incued glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma. J Allergy Clin Immunol 109:649-657. (Pubitemid 34327193)
-
(2002)
Journal of Allergy and Clinical Immunology
, vol.109
, Issue.4
, pp. 649-657
-
-
Irusen, E.1
Matthews, J.G.2
Takahashi, A.3
Barnes, P.J.4
Chung, K.F.5
Adcock, I.M.6
-
24
-
-
29544449036
-
2-adrenergic receptor function, response, and regulation
-
2-adrenergic receptor function, response, and regulation. J Allergy Clin Immunol 117:18-24.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 18-24
-
-
Johnson, M.1
-
25
-
-
37349117437
-
2-adrenoceptor agonists synergistically enhance glucocorticoid-dependent transcription in human airway epithelial and smooth muscle cells
-
2-adrenoceptor agonists synergistically enhance glucocorticoid-dependent transcription in human airway epithelial and smooth muscle cells. Mol Pharmacol 73:203-214.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 203-214
-
-
Kaur, M.1
Chivers, J.E.2
Giembycz, M.A.3
Newton, R.4
-
26
-
-
79961173346
-
2-subtype of adrenoceptors mediates inhibition of pro-fibrotic events in human lung fibroblasts
-
2-subtype of adrenoceptors mediates inhibition of pro-fibrotic events in human lung fibroblasts. Naunyn Schmiedebergs Arch Pharmacol 384:133-145.
-
(2011)
Naunyn Schmiedebergs Arch Pharmacol
, vol.384
, pp. 133-145
-
-
Lamyel, F.1
Warnken-Uhlich, M.2
Seemann, W.K.3
Mohr, K.4
Kostenis, E.5
Ahmedat, A.S.6
Smit, M.7
Gosens, R.8
Meurs, H.9
Miller-Larsson, A.10
-
27
-
-
0032563291
-
G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization
-
Lefkowitz RJ (1998) G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization. J Biol Chem 273:18677-18680.
-
(1998)
J Biol Chem
, vol.273
, pp. 18677-18680
-
-
Lefkowitz, R.J.1
-
28
-
-
77956644353
-
Regulation of T cells in airway disease by beta-agonist
-
Loza MJ and Penn RB (2010) Regulation of T cells in airway disease by beta-agonist. Front Biosci (Schol Ed) 2:969-979.
-
(2010)
Front Biosci (Schol Ed)
, vol.2
, pp. 969-979
-
-
Loza, M.J.1
Penn, R.B.2
-
32
-
-
0024496427
-
2-adrenergic tocolytic therapy: Correlation with lymphocyte beta-adrenoceptors
-
Michel MC, Pingsmann A, Nohlen M, Siekmann U, and Brodde OE (1989) Decreased myometrial beta-adrenoceptors in women receiving beta-2-adrenergic tocolytic therapy: correlation with lymphocyte beta-adrenoceptors. Clin Pharmacol Ther 45:1-8. (Pubitemid 19047139)
-
(1989)
Clinical Pharmacology and Therapeutics
, vol.45
, Issue.1
, pp. 1-8
-
-
Michel, M.C.1
Pingsmann, A.2
Nohlen, M.3
Siekmann, U.4
Brodde, O.-E.5
-
33
-
-
70449552889
-
Endosomes: A legitimate platform for the signaling train
-
Murphy JE, Padilla BE, Hasdemir B, Cottrell GS, and Bunnett NW (2009) Endosomes: a legitimate platform for the signaling train. Proc Natl Acad Sci USA 106:17615-17622.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 17615-17622
-
-
Murphy, J.E.1
Padilla, B.E.2
Hasdemir, B.3
Cottrell, G.S.4
Bunnett, N.W.5
-
34
-
-
19944432162
-
Mitogen-activated protein kinases and asthma
-
DOI 10.1002/jcp.20169
-
Pelaia G, Cuda G, Vatrella A, Gallelli L, Caraglia M, Marra M, Abbruzzese A, Caputi M, Maselli R, Costanzo FS, et al. (2005) Mitogen-activated protein kinases and asthma. J Cell Physiol 202:642-653. (Pubitemid 40175839)
-
(2005)
Journal of Cellular Physiology
, vol.202
, Issue.3
, pp. 642-653
-
-
Pelaia, G.1
Cuda, G.2
Vatrella, A.3
Gallelli, L.4
Caraglia, M.5
Marra, M.6
Abbruzzese, A.7
Caputi, M.8
Maselli, R.9
Costanzo, F.S.10
Marsico, S.A.11
-
35
-
-
47149117849
-
Embracing emerging paradigms of G protein-coupled receptor agonism and signaling to address airway smooth muscle pathobiology in asthma
-
Penn RB (2008) Embracing emerging paradigms of G protein-coupled receptor agonism and signaling to address airway smooth muscle pathobiology in asthma. Naunyn Schmiedebergs Arch Pharmacol 378:149-169.
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.378
, pp. 149-169
-
-
Penn, R.B.1
-
36
-
-
47149116349
-
Pulmonary fibroblasts, an emerging target for anti-obstructive drugs
-
Racke K, Haag S, Babulayan A, and Warnken M (2008) Pulmonary fibroblasts, an emerging target for anti-obstructive drugs. Naunyn Schmiedebergs Arch Pharmacol 378:193-201.
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.378
, pp. 193-201
-
-
Racke, K.1
Haag, S.2
Babulayan, A.3
Warnken, M.4
-
37
-
-
0037180086
-
2 agonists on bronchial airwaysmooth muscle cells through synchronised cellular signalling
-
2 agonists on bronchial airwaysmooth muscle cells through synchronised cellular signalling. Lancet 360:1293-1299.
-
(2002)
Lancet
, vol.360
, pp. 1293-1299
-
-
Roth, M.1
Johnson, P.R.2
Rüdiger, J.J.3
King, G.G.4
Ge, Q.5
Burgess, J.K.6
Anderson, G.7
Tamm, M.8
Black, J.L.9
-
39
-
-
29944435077
-
Lung fibroblast proteoglycan production induced by serum is inhibited by budesonide and formoterol
-
DOI 10.1165/rcmb.2005-0048OC
-
Todorova L, Gürcan E, Miller-Larsson A, and Westergren-Thorsson G (2006) Lung fibroblast proteoglycan production induced by serum is inhibited by budesonide and formoterol. Am J Respir Cell Mol Biol 34:92-100. (Pubitemid 43042861)
-
(2006)
American Journal of Respiratory Cell and Molecular Biology
, vol.34
, Issue.1
, pp. 92-100
-
-
Todorova, L.1
Gurcan, E.2
Miller-Larsson, A.3
Westergren-Thorsson, G.4
-
40
-
-
2442682766
-
The pro-apoptotic protein Bim is a convergence point for cAMP/protein kinase A- and glucocorticoid-promoted apoptosis of lymphoid cells
-
DOI 10.1074/jbc.M310643200
-
Zhang L and Insel PA (2004) The pro-apoptotic protein Bim is a convergence point for cAMP/protein kinase A- and glucocorticoid-promoted apoptosis of lymphoid cells. J Biol Chem 279:20858-20865. (Pubitemid 38656482)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.20
, pp. 20858-20865
-
-
Zhang, L.1
Insel, P.A.2
|