Regulation of airway smooth muscle α-actin expression by glucocorticoids

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 292, Issue 1, 2007, Pages

  Goldsmith, Adam M ^a   Hershenson, Marc B ^a,b   Wolbert, Miguel P ^a   Bentley, J Kelley ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Corticosteroids; Fluticasone; Hypertrophy; Salmeterol; Transforming growth factor

Indexed keywords

ACETYLCHOLINE; ALPHA SMOOTH MUSCLE ACTIN; DACTINOMYCIN; DEXAMETHASONE; FLUTICASONE; GLUCOCORTICOID; MESSENGER RNA; POTASSIUM CHLORIDE; SALMETEROL; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BRONCHUS MUSCLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN STABILITY; PROTEIN SYNTHESIS; RNA TRANSLATION; STEADY STATE;

ACTINS; ALBUTEROL; ANDROSTADIENES; BRONCHI; CELLS, CULTURED; DEXAMETHASONE; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; MUSCLE, SMOOTH; RNA STABILITY; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 33846264126     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00269.2006     Document Type: Article

References (43)

1. Adcock IM, Ito K, Barnes PJ. Glucocorticoids: effects on gene transcription. Proc Am Thorac Soc 1: 247-254, 2004.
2. Ammit AJ, Lazaar AL, Irani C, O'Neill GM, Gordon ND, Amrani Y, Penn RB, Panettieri RA Jr. Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells. Modulation by glucocorticoids and beta-agonists. Am J Respir Cell Mol Biol 26: 465-474, 2002.
3. Bao J, Oishi K, Yamada T, Liu L, Nakamura A, Uchida MK, Kohama K. Role of the short isoform of myosin light chain kinase in the contraction of cultured smooth muscle cells as examined by its down-regulation. Proc Natl Acad Sci USA 99: 9556-9561, 2002.
4. Benayoun L, Druilhe A, Dombret MC, Aubier M, Pretolani M. Airway structural alterations selectively associated with severe asthma. Am J Respir Crit Care Med 167: 1360-1368, 2003.
5. Costelli P, Garcia-Martinez C, Llovera M, Carbo N, Lopez-Soriano FJ, Agell N, Tessitore L, Baccino FM, Argiles JM. Muscle protein waste in tumor-bearing rats is effectively antagonized by a beta 2-adrenergic agonist (clenbuterol). Role of the ATP-ubiquitin-dependent proteolytic pathway. J Clin Invest 95: 2367-2372, 1995.
6. Dekhuijzen PN, Gayan-Ramirez G, de Bock V, Dom R, Decramer M. Triamcinolone and prednisolone affect contractile properties and histopathology of rat diaphragm differently. J Clin Invest 92: 1534-1542, 1993.
7. Ebina M, Takahashi T, Chiba T, Motomiya M. Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study. Am Rev Respir Dis 148: 720-726, 1993.
8. Eghbali M, Tomek R, Woods C, Bhambi B. Cardiac fibroblasts are predisposed to convert into myocyte phenotype: specific effect of transforming growth factor-β. Proc Natl Acad Sci USA 88: 795-799, 1991.
9. Fernandes D, Guida E, Koutsoubos V, Harris T, Vadiveloo P, Wilson JW, Stewart AG. Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle. Am J Respir Cell Mol Biol 21: 77-88, 1999.
10. Goldsmith AM, Bentley JK, Zhou L, Jia Y, Bitar KN, Fingar DC, Hershenson MB. Transforming growth factor-beta induces airway smooth muscle hypertrophy. Am J Respir Cell Mol Biol 34: 247-254, 2006.
11. Hirst SJ, Lee TH. Airway smooth muscle as a target of glucocorticoid action in the treatment of asthma. Am J Respir Crit Care Med 158: 201S-206S, 1998.
12. Johnson M. The anti-inflammatory profile of fluticasone propionate. Allergy 50: 11-14, 1995.
13. Kayali AG, Goodman MN, Lin J, Young VR. Insulin- and thyroid hormone-independent adaptation of myofibrillar proteolysis to glucocorticoids. Am J Physiol Endocrinol Metab 259: E699-E705, 1990.
14. Kayali AG, Young VR, Goodman MN. Sensitivity of myofibrillar proteins to glucocorticoid-induced muscle proteolysis. Am J Physiol Endocrinol Metab 252: E621-E626, 1987.
15. Lahiri T, Moore PE, Baraldo S, Whitehead TR, McKenna MD, Panettieri RA Jr, and Shore SA. Effect of IL-1beta on CRE-dependent gene expression in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 283: L1239-L1246, 2002.
16. Leung SY, Eynott P, Nath P, Chung KF. Effects of ciclesonide and fluticasone propionate on allergen-induced airway inflammation and remodeling features. J Allergy Clin Immunol 115: 989-996, 2005.
17. Liu Z, Li G, Kimball SR, Jahn LA, Barrett EJ. Glucocorticoids modulate amino acid-induced translation initiation in human skeletal muscle. Am J Physiol Endocrinol Metab 287: E275-E281, 2004.
18. Long W, Wei L, Barrett EJ. Dexamethasone inhibits the stimulation of muscle protein synthesis and PHAS-I and p70 S6-kinase phosphorylation. Am J Physiol Endocrinol Metab 280: E570-E575, 2001.
19. 2+ uptake and myofibrillar disassembly in primary muscle cell culture. Biosci Biotechnol Biochem 67: 244-249, 2003.
20. Minshall EM, Leung DY, Martin RJ, Song YL, Cameron L, Ernst P, Hamid Q. Eosinophil-associated TGF-β1 mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 17: 326-333, 1997.
21. Musa NL, Ramakrishnan M, Li J, Kartha S, Liu P, Pestell RG, Hershenson MB. Forskolin inhibits cyclin D1 expression in cultured airway smooth-muscle cells. Am J Respir Cell Mol Biol 20: 352-358, 1999.
22. Nomura A, Uchida Y, Sakamoto T, Ishii Y, Masuyama K, Morishima Y, Hirano K, Sekizawa K. Increases in collagen type I collagen synthesis in asthma: the role of eosinophils and transforming growth factor-beta. Clin Exp Allergy 32: 860-865, 2002.
23. Ohno I, Nitta Y, Yamauchi K, Hoshi H, Honma M, Woolley K, O'Byrne P, Tamura G, Jordana M, Shirato K. Transforming growth factor beta 1 gene expression by eosinophils in asthmatic airway inflammation. Am J Respir Cell Mol Biol 15: 404-409, 1996.
24. Olivieri D, Chetta A, Del Donno M, Bertorelli G, Casalina A, Pesci A, Testi R, Foresi A. Effect of short-term treatment with low-dose inhaled fluticasone proprionate on airway inflammation and remodelling in mild asthma: a placebo controlled study. Am J Respir Crit Care Med 155: 1864-1871, 1997.
25. Owens G, Geisterfer A, Yang Y, Komoriya A. Transforming growth factor-beta-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells. J Cell Biol 107: 771-780, 1988.
26. Panettieri RA Jr. Effects of corticosteroids on structural cells in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 1: 231-234, 2004.
27. Patil SB, Pawar MD, Bitar KN. Phosphorylated HSP27 essential for acetylcholine-induced association of RhoA with PKCα. Am J Physiol Gastrointest Liver Physiol 286: G635-G644, 2004.
28. Scott MG, Swan C, Jobson TM, Rees S, Hall IP. Effects of a range of β2 adrenoceptor agonists on changes in intracellular cyclic AMP and on cyclic AMP driven gene expression in cultured human airway smooth muscle cells. Br J Pharmacol 128: 721-729, 1999.
29. Shah OJ, Anthony JC, Kimball SR, Jefferson LS. Glucocorticoids oppose translational control by leucine in skeletal muscle. Am J Physiol Endocrinol Metab 279: E1185-E1190, 2000.
30. Shah OJ, Kimball SR, Jefferson LS. Acute attenuation of translation initiation and protein synthesis by glucocorticoids in skeletal muscle. Am J Physiol Endocrinol Metab 278: E76-E82, 2000.
31. Shah OJ, Kimball SR, Jefferson LS. Among translational effectors, p70S6k is uniquely sensitive to inhibition by glucocorticoids. Biochem J 347: 389-397, 2000.
32. Shah OJ, Kimball SR, Jefferson LS. Glucocorticoids abate p70S6k and eIF4E function in L6 skeletal myoblasts. Am J Physiol Endocrinol Metab 279: E74-E82, 2000.
33. Stellato C. Post-transcriptional and nongenomic effects of glucocorticoids. Proc Am Thorac Soc 1: 255-263, 2004.
34. Stewart AG, Fernandes DJ, Tomlinson PR. The effect of glucocorticoids on proliferation of human cultured airway smooth muscle. Br J Pharmacol 116: 3219-3226, 1995.
35. Stewart AG, Harris T, Fernandes DJ, Schachte LC, Koutsoubos V, Guida E, Ravenhall CE, Vadiveloo P, Wilson JW. Beta 2-adrenergic receptor agonists and cAMP arrest human cultured airway smooth muscle cells in the G1 phase of the cell cycle: role of proteasome degradation of cyclin D1. Mol Pharmacol 56: 1079-1086, 1999.
36. Tillie-Leblond I, Pugin J, Marquette CH, Lamblin C, Saulnier F, Brichet A, Wallaert B, Tonnel AB, Gosset P. Balance between proinflammatory cytokines and their inhibitors in bronchial lavage from patients with status asthmaticus. Am J Respir Crit Care Med 159: 487-494, 1999.
37. Tomlinson PR, Wilson JW, Stewart AG. Salbutamol inhibits the proliferation of human airway smooth muscle cells grown in culture: relationship to elevated cAMP levels. Biochem Pharmacol 49: 1809-1819, 1995.
38. Trigg CJ, Manolitsas ND, Wang J, Calderon MA, McAulay A, Jordan SE, Herdman MJ, Jhalli N, Duddle JM, Hamilton SA, Devalia JL, Davies RJ. Placebo-controlled immunopathologic study of four months of inhaled corticosteroids in asthma. Am J Respir Crit Care Med 150: 17-22, 1994.
39. Tsai WC, Tang FT, Wong MK, Pang JH. Inhibition of tendon cell migration by dexamethasone is correlated with reduced alpha-smooth muscle actin gene expression: a potential mechanism of delayed tendon healing. J Orthop Res 21: 265-271, 2003.
40. Wing SS, Goldberg AL. Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting. Am J Physiol Endocrinol Metab 264: E668-E676, 1993.
41. Xiong W, Pestell RG, Watanabe G, Li J, Rosner MR, Hershenson MB. Cyclin D1 is required for S phase traversal in bovine tracheal myocytes. Am J Physiol Lung Cell Mol Physiol 272: L1205-L1210, 1997.
42. Zhou L, Goldsmith AM, Bentley JK, Jia Y, Rodriguez ML, Abe MK, Fingar DC, Hershenson MB. 4E-Binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy. Am J Respir Cell Mol Biol 33: 195-202, 2005.
43. Zhou L, Li J, Goldsmith AM, Newcomb DC, Giannola DM, Vosk RG, Eves EM, Rosner MR, Solway J, Hershenson MB. Human bronchial smooth muscle cell lines show a hypertrophic phenotype typical of severe asthma. Am J Respir Crit Care Med 169: 703-711, 2004.