4-Hydroxynonenal inhibits telomerase activity and hTERT expression in human leukemic cell lines

Free Radical Biology and Medicine

Volumn 40, Issue 9, 2006, Pages 1578-1591

  Pizzimenti, Stefania ^a   Briatore, Federica ^a   Laurora, Stefano ^a   Toaldo, Cristina ^a   Maggio, Maddalena ^a   De Grandi, Michela ^a   Meaglia, Laura ^a   Menegatti, Elisa ^a   Giglioni, Barbara ^b   Dianzani, Mario U ^a   Barrera, Giuseppina ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b CNR   (Italy)

Author keywords

4 Hydroxynonenal; DNA binding; E box; Free radicals; HL 60; hTERT, c Myc; Mad 1; ML 1; p53; Sp 1; Telomerase activity; U937

Indexed keywords

4 HYDROXYNONENAL; DNA; MYC PROTEIN; PROTEIN MAD1; PROTEIN P53; TELOMERASE; TELOMERASE INHIBITOR; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL STRAIN; CELL STRAIN HL 60; CONTROLLED STUDY; DNA BINDING; DOWN REGULATION; DRUG INHIBITION; E BOX ELEMENT; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; TRANSCRIPTION TERMINATION;

ALDEHYDES; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CYSTEINE PROTEINASE INHIBITORS; DNA-BINDING PROTEINS; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; OXIDATIVE STRESS; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TELOMERASE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33646040063     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2005.12.024     Document Type: Article

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