Catalytic Inactivation of Protein Tyrosine Phosphatase CD45 and Protein Tyrosine Phosphatase 1B by Polyaromatic Quinones

Biochemistry

Volumn 43, Issue 14, 2004, Pages 4294-4303

  Wang, Qingping ^a   Dubé, Daniel ^a   Friesen, Richard W ^a   LeRiche, Tammy G ^a   Bateman, Kevin P ^a   Trimble, Laird ^a   Sanghara, Joe ^a   Pollex, Rebecca ^a   Ramachandran, Chidambaram ^a   Gresser, Michael J ^a   Huang, Zheng ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; DISEASES; ENZYME INHIBITION; ENZYMES; GLUCOSE;

CATALYTIC INACTIVATION; GLUCOSE NORMALIZATION;

BIOCHEMISTRY;

2 NITRO 9,10 PHENANTHRENEDIONE; AMIDE; CATALASE; CD45 ANTIGEN; CYSTEINE; DITHIOTHREITOL; ENZYME INHIBITOR; GLUCOSE; HYDROXYLAMINE; IODINE 125; LEUKOCYTE COMMON ANTIGEN RELATED PROTEIN; OXYGEN; PHENANTHRENE DERIVATIVE; PHENANTHRENEQUINONE; PHOSPHOTYROSINE; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE CD45; QUINONE DERIVATIVE; RADICAL; REACTIVE OXYGEN METABOLITE; SEMIQUINONE; SULFENIC ACID DERIVATIVE; SULFENYLAMIDE DERIVATIVE; SULFINIC ACID DERIVATIVE; SULFONIC ACID DERIVATIVE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; ENZYME INACTIVATION; ENZYME INHIBITOR COMPLEX; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; GROWTH INHIBITION; IMMUNE DEFICIENCY; ISOTOPE LABELING; KINETICS; OXIDATION; OXIDATION REDUCTION REACTION; PH; POLLUTANT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RADIOACTIVITY; REGULATORY MECHANISM;

ANTIGENS, CD45; CATALYSIS; CYSTEINE; DITHIOTHREITOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ENZYME REACTIVATORS; HUMANS; HYDROXYLAMINE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; IODINE RADIOISOTOPES; MEMBRANE PROTEINS; OXIDATION-REDUCTION; OXYGEN; PHENANTHRENES; PHOSPHOPROTEINS; PROTEIN-TYROSINE-PHOSPHATASE; QUINONES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFENIC ACIDS; SULFONIC ACIDS;

EID: 11144358556     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035986e     Document Type: Article

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