Structure of the 2-aminopurine-cytosine base pair formed in the polymerase active site of the RB69 Y567A-DNA polymerase

Biochemistry

Volumn 50, Issue 46, 2011, Pages 10136-10149

  Reha Krantz, Linda J ^a   Hariharan, Chithra ^a   Subuddhi, Usharani ^a   Xia, Shuangluo ^b   Zhao, Chao ^b   Beckman, Jeff ^b   Christian, Thomas ^b   Konigsberg, William ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2-AMINOPURINE; 2-AMINOPURINE (2AP); AMINO GROUP; BASE PAIRS; BASE SELECTIVITY; DNA POLYMERASE; INCREASED FLEXIBILITY; NUCLEOTIDE BINDING; POLYMERASE ACTIVE SITE;

DNA; PROTONS;

POLYMERS;

2 AMINOPURINE; 2 AMINOPURINE CYTOSINE; CYTOSINE DERIVATIVE; DEOXYCYTIDINE TRIPHOSPHATE; DNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; BASE PAIRING; CHEMICAL STRUCTURE; EQUILIBRIUM CONSTANT; FLUORESCENCE ANALYSIS; HYDROGEN BOND; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; X RAY CRYSTALLOGRAPHY;

2-AMINOPURINE; AMINO ACID SUBSTITUTION; BACTERIOPHAGES; BASE PAIRING; CATALYTIC DOMAIN; CYTIDINE MONOPHOSPHATE; CYTIDINE TRIPHOSPHATE; CYTOSINE; DNA-DIRECTED DNA POLYMERASE; MODELS, MOLECULAR; PROTEIN BINDING; URIDINE TRIPHOSPHATE; VIRAL PROTEINS;

PROKARYOTA;

EID: 81255142769     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi2014618     Document Type: Article

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