Exonuclease-polymerase active site partitioning of primer-template DNA strands and equilibrium Mg2+ binding properties of bacteriophage T4 DNA polymerase

Biochemistry

Volumn 37, Issue 28, 1998, Pages 10144-10155

  Beechem, Joseph M ^a   Otto, Michael R ^a,e   Bloom, Linda B ^d,f   Eritja, Ramon ^c   Reha Krantz, Linda J ^b   Goodman, Myron F ^d  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

^c Europ Molec Biology Organization   (Germany)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e Axiom Biotechnologies Inc   (United States)

^f ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOPURINE; DNA POLYMERASE; EXONUCLEASE; MAGNESIUM ION;

ARTICLE; BACTERIOPHAGE T4; BINDING AFFINITY; BINDING SITE; CONFORMATIONAL TRANSITION; DNA TEMPLATE; ENZYME ASSAY; ENZYME BINDING; FLUORESCENCE; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN BINDING; REACTION ANALYSIS; STEADY STATE;

2-AMINOPURINE; BACTERIOPHAGE T4; BINDING SITES; DNA; DNA PRIMERS; DNA, SINGLE-STRANDED; DNA-DIRECTED DNA POLYMERASE; EXONUCLEASES; FLUORESCENCE POLARIZATION; MAGNESIUM; MUTAGENESIS, SITE-DIRECTED; SPECTROMETRY, FLUORESCENCE; TEMPLATES, GENETIC; THIONUCLEOTIDES; VIRAL PROTEINS;

EID: 0032516443     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980074b     Document Type: Article

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