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Volumn 2, Issue 10, 2011, Pages 845-854

SDF-1/CXCR4 axis modulates bone marrow mesenchymal stem cell apoptosis, migration and cytokine secretion

Author keywords

bone marrow mesenchymal stem cells; migration; SDF 1 CXCR4; secretion; survival

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CYTOKINE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; STROMAL CELL DERIVED FACTOR 1; VASCULOTROPIN;

EID: 80955157950     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-011-1097-z     Document Type: Article
Times cited : (208)

References (41)
  • 1
    • 9344255481 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury
    • Abbott, J. D., Huang, Y., Liu, D., Hickey, R., Krause, D. S., and Giordano, F. J. (2004). Stromal cell-derived factor-1alpha plays a critical role in stem cell recruitment to the heart after myocardial infarction but is not sufficient to induce homing in the absence of injury. Circulation 110, 3300-3305.
    • (2004) Circulation , vol.110 , pp. 3300-3305
    • Abbott, J.D.1    Huang, Y.2    Liu, D.3    Hickey, R.4    Krause, D.S.5    Giordano, F.J.6
  • 4
    • 0038500953 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G(alpha)i proteins and enhances engraftment of competitive, repopulating stem cells
    • Broxmeyer, H. E., Kohli, L., Kim, C. H., Lee, Y., Mantel, C., Cooper, S., Hangoc, G., Shaheen, M., Li, X., and Clapp, D. W. (2003). Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G(alpha)i proteins and enhances engraftment of competitive, repopulating stem cells. J Leukoc Biol 73, 630-638.
    • (2003) J Leukoc Biol , vol.73 , pp. 630-638
    • Broxmeyer, H.E.1    Kohli, L.2    Kim, C.H.3    Lee, Y.4    Mantel, C.5    Cooper, S.6    Hangoc, G.7    Shaheen, M.8    Li, X.9    Clapp, D.W.10
  • 5
    • 51349089610 scopus 로고    scopus 로고
    • Mobilization of mesenchymal stem cells by granulocyte colony-stimulating factor in rats with acute myocardial infarction
    • Cheng, Z., Liu, X., Ou, L., Zhou, X., Liu, Y., Jia, X., Zhang, J., Li, Y., and Kong, D. (2008a). Mobilization of mesenchymal stem cells by granulocyte colony-stimulating factor in rats with acute myocardial infarction. Cardiovasc Drugs Ther 22, 363-371.
    • (2008) Cardiovasc Drugs Ther , vol.22 , pp. 363-371
    • Cheng, Z.1    Liu, X.2    Ou, L.3    Zhou, X.4    Liu, Y.5    Jia, X.6    Zhang, J.7    Li, Y.8    Kong, D.9
  • 6
    • 56549096399 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor exacerbates cardiac fibrosis after myocardial infarction in a rat model of permanent occlusion
    • Cheng, Z., Ou, L., Liu, Y., Liu, X., Li, F., Sun, B., Che, Y., Kong, D., Yu, Y., and Steinhoff, G. (2008b). Granulocyte colony-stimulating factor exacerbates cardiac fibrosis after myocardial infarction in a rat model of permanent occlusion. Cardiovasc Res 80, 425-434.
    • (2008) Cardiovasc Res , vol.80 , pp. 425-434
    • Cheng, Z.1    Ou, L.2    Liu, Y.3    Liu, X.4    Li, F.5    Sun, B.6    Che, Y.7    Kong, D.8    Yu, Y.9    Steinhoff, G.10
  • 7
    • 39849097361 scopus 로고    scopus 로고
    • Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance
    • Cheng, Z., Ou, L., Zhou, X., Li, F., Jia, X., Zhang, Y., Liu, X., Li, Y., Ward, C. A., Melo, L. G., et al. (2008c). Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performance. Mol Ther 16, 571-579.
    • (2008) Mol Ther , vol.16 , pp. 571-579
    • Cheng, Z.1    Ou, L.2    Zhou, X.3    Li, F.4    Jia, X.5    Zhang, Y.6    Liu, X.7    Li, Y.8    Ward, C.A.9    Melo, L.G.10
  • 8
    • 51849111566 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 and -4 promote the proliferation of bone marrow mesenchymal stem cells by the activation of the PI3K-Akt and ERK1/2 signaling pathways
    • Choi, S. C., Kim, S. J., Choi, J. H., Park, C. Y., Shim, W. J., and Lim, D. S. (2008). Fibroblast growth factor-2 and -4 promote the proliferation of bone marrow mesenchymal stem cells by the activation of the PI3K-Akt and ERK1/2 signaling pathways. Stem Cells Dev 17, 725-736.
    • (2008) Stem Cells Dev , vol.17 , pp. 725-736
    • Choi, S.C.1    Kim, S.J.2    Choi, J.H.3    Park, C.Y.4    Shim, W.J.5    Lim, D.S.6
  • 9
    • 22144475112 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and longterm effects
    • Dai, W., Hale, S. L., Martin, B. J., Kuang, J. Q., Dow, J. S., Wold, L. E., and Kloner, R. A. (2005). Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and longterm effects. Circulation 112, 214-223.
    • (2005) Circulation , vol.112 , pp. 214-223
    • Dai, W.1    Hale, S.L.2    Martin, B.J.3    Kuang, J.Q.4    Dow, J.S.5    Wold, L.E.6    Kloner, R.A.7
  • 10
    • 20044391264 scopus 로고    scopus 로고
    • A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors
    • Dziembowska, M., Tham, T. N., Lau, P., Vitry, S., Lazarini, F., and Dubois-Dalcq, M. (2005). A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors. Glia 50, 258-269.
    • (2005) Glia , vol.50 , pp. 258-269
    • Dziembowska, M.1    Tham, T.N.2    Lau, P.3    Vitry, S.4    Lazarini, F.5    Dubois-Dalcq, M.6
  • 11
    • 56549096547 scopus 로고    scopus 로고
    • Mesenchymal stem cells engineered to overexpress stem cell factor improve cardiac function but have malignant potential
    • Fazel, S. S., Angoulvant, D., Butany, J., Weisel, R. D., and Li, R. K. (2008). Mesenchymal stem cells engineered to overexpress stem cell factor improve cardiac function but have malignant potential. J Thorac Cardiovasc Surg 136, 1388-1389.
    • (2008) J Thorac Cardiovasc Surg , vol.136 , pp. 1388-1389
    • Fazel, S.S.1    Angoulvant, D.2    Butany, J.3    Weisel, R.D.4    Li, R.K.5
  • 13
    • 0033558798 scopus 로고    scopus 로고
    • VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling
    • Gupta, K., Kshirsagar, S., Li, W., Gui, L., Ramakrishnan, S., Gupta, P., Law, P. Y., and Hebbel, R. P. (1999). VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling. Exp Cell Res 247, 495-504.
    • (1999) Exp Cell Res , vol.247 , pp. 495-504
    • Gupta, K.1    Kshirsagar, S.2    Li, W.3    Gui, L.4    Ramakrishnan, S.5    Gupta, P.6    Law, P.Y.7    Hebbel, R.P.8
  • 14
    • 54149109538 scopus 로고    scopus 로고
    • Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation
    • Haider, H. Kh., and Ashraf, M. (2008). Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation. J Mol Cell Cardiol 45, 554-566.
    • (2008) J Mol Cell Cardiol , vol.45 , pp. 554-566
    • Haider, H.K.1    Ashraf, M.2
  • 15
    • 34548174756 scopus 로고    scopus 로고
    • Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis
    • Hu, X., Dai, S., Wu, W. J., Tan, W., Zhu, X., Mu, J., Guo, Y., Bolli, R., and Rokosh, G. (2007). Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis. Circulation 116, 654-663.
    • (2007) Circulation , vol.116 , pp. 654-663
    • Hu, X.1    Dai, S.2    Wu, W.J.3    Tan, W.4    Zhu, X.5    Mu, J.6    Guo, Y.7    Bolli, R.8    Rokosh, G.9
  • 16
    • 11044219755 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 (SDF-1) signalling regulates human placental trophoblast cell survival
    • Jaleel, M. A., Tsai, A. C., Sarkar, S., Freedman, P. V., and Rubin, L. P. (2004). Stromal cell-derived factor-1 (SDF-1) signalling regulates human placental trophoblast cell survival. Mol Hum Reprod 10, 901-909.
    • (2004) Mol Hum Reprod , vol.10 , pp. 901-909
    • Jaleel, M.A.1    Tsai, A.C.2    Sarkar, S.3    Freedman, P.V.4    Rubin, L.P.5
  • 17
    • 8144228678 scopus 로고    scopus 로고
    • Enhancement of cell survival by stromal cell-derived factor-1/CXCL12 involves activation of CREB and induction of Mcl-1 and c-Fos in factor-dependent human cell line MO7e
    • Joo, E. K., Broxmeyer, H. E., Kwon, H. J., Kang, H. B., Kim, J. S., Lim, J. S., Choe, Y. K., Choe, I. S., Myung, P. K., and Lee, Y. (2004). Enhancement of cell survival by stromal cell-derived factor-1/CXCL12 involves activation of CREB and induction of Mcl-1 and c-Fos in factor-dependent human cell line MO7e. Stem Cells Dev 13, 563-570.
    • (2004) Stem Cells Dev , vol.13 , pp. 563-570
    • Joo, E.K.1    Broxmeyer, H.E.2    Kwon, H.J.3    Kang, H.B.4    Kim, J.S.5    Lim, J.S.6    Choe, Y.K.7    Choe, I.S.8    Myung, P.K.9    Lee, Y.10
  • 19
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms
    • Kinnaird, T., Stabile, E., Burnett, M. S., Lee, C. W., Barr, S., Fuchs, S., and Epstein, S. E. (2004a). Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ Res 94, 678-685.
    • (2004) Circ Res , vol.94 , pp. 678-685
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Lee, C.W.4    Barr, S.5    Fuchs, S.6    Epstein, S.E.7
  • 20
    • 1842486565 scopus 로고    scopus 로고
    • Local delivery of marrowderived stromal cells augments collateral perfusion through paracrine mechanisms
    • Kinnaird, T., Stabile, E., Burnett, M. S., Shou, M., Lee, C. W., Barr, S., Fuchs, S., and Epstein, S. E. (2004b). Local delivery of marrowderived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation 109, 1543-1549.
    • (2004) Circulation , vol.109 , pp. 1543-1549
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Shou, M.4    Lee, C.W.5    Barr, S.6    Fuchs, S.7    Epstein, S.E.8
  • 22
    • 0344392953 scopus 로고    scopus 로고
    • Apoptosis and oxidants in the heart
    • Kumar, D., and Jugdutt, B. I. (2003). Apoptosis and oxidants in the heart. J Lab Clin Med 142, 288-297.
    • (2003) J Lab Clin Med , vol.142 , pp. 288-297
    • Kumar, D.1    Jugdutt, B.I.2
  • 23
    • 0037082510 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism
    • Lataillade, J. J., Clay, D., Bourin, P., Hérodin, F., Dupuy, C., Jasmin, C., and Le Bousse-Kerdilès, M. C. (2002). Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism. Blood 99, 1117-1129.
    • (2002) Blood , vol.99 , pp. 1117-1129
    • Lataillade, J.J.1    Clay, D.2    Bourin, P.3    Hérodin, F.4    Dupuy, C.5    Jasmin, C.6    Le Bousse-Kerdilès, M.C.7
  • 25
    • 0141796313 scopus 로고    scopus 로고
    • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
    • Mangi, A. A., Noiseux, N., Kong, D., He, H., Rezvani, M., Ingwall, J. S., and Dzau, V. J. (2003). Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med 9, 1195-1201.
    • (2003) Nat Med , vol.9 , pp. 1195-1201
    • Mangi, A.A.1    Noiseux, N.2    Kong, D.3    He, H.4    Rezvani, M.5    Ingwall, J.S.6    Dzau, V.J.7
  • 26
    • 49249113555 scopus 로고    scopus 로고
    • Current status and future prospects for cell transplantation to prevent congestive heart failure
    • Menasché, P. (2008). Current status and future prospects for cell transplantation to prevent congestive heart failure. Semin Thorac Cardiovasc Surg 20, 131-137.
    • (2008) Semin Thorac Cardiovasc Surg , vol.20 , pp. 131-137
    • Menasché, P.1
  • 27
    • 0029778441 scopus 로고    scopus 로고
    • Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction
    • Misao, J., Hayakawa, Y., Ohno, M., Kato, S., Fujiwara, T., and Fujiwara, H. (1996). Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation 94, 1506-1512.
    • (1996) Circulation , vol.94 , pp. 1506-1512
    • Misao, J.1    Hayakawa, Y.2    Ohno, M.3    Kato, S.4    Fujiwara, T.5    Fujiwara, H.6
  • 29
    • 38849108184 scopus 로고    scopus 로고
    • Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardium
    • Pasha, Z., Wang, Y., Sheikh, R., Zhang, D., Zhao, T., and Ashraf, M. (2008). Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardium. Cardiovasc Res 77, 134-142.
    • (2008) Cardiovasc Res , vol.77 , pp. 134-142
    • Pasha, Z.1    Wang, Y.2    Sheikh, R.3    Zhang, D.4    Zhao, T.5    Ashraf, M.6
  • 30
    • 0032530301 scopus 로고    scopus 로고
    • Apoptotic regulation in primitive hematopoietic precursors
    • Peters, R., Leyvraz, S., and Perey, L. (1998). Apoptotic regulation in primitive hematopoietic precursors. Blood 92, 2041-2052.
    • (1998) Blood , vol.92 , pp. 2041-2052
    • Peters, R.1    Leyvraz, S.2    Perey, L.3
  • 32
    • 0032409781 scopus 로고    scopus 로고
    • Bcl-2 family proteins
    • Reed, J. C. (1998). Bcl-2 family proteins. Oncogene 17, 3225-3236.
    • (1998) Oncogene , vol.17 , pp. 3225-3236
    • Reed, J.C.1
  • 35
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • Toma, C., Pittenger, M. F., Cahill, K. S., Byrne, B. J., and Kessler, P. D. (2002). Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 105, 93-98.
    • (2002) Circulation , vol.105 , pp. 93-98
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3    Byrne, B.J.4    Kessler, P.D.5
  • 36
    • 77954944580 scopus 로고    scopus 로고
    • Mesenchymal Stem Cell Therapy for Treatment of Cardiovascular Disease: Helping people sooner or later
    • Trivedi, P. S., Tray, N. J., Nguyen, T. D., Nigam, N., and Gallicano, G. I. (2010). Mesenchymal Stem Cell Therapy for Treatment of Cardiovascular Disease: Helping people sooner or later. Stem Cells Dev 19, 1109-1120.
    • (2010) Stem Cells Dev , vol.19 , pp. 1109-1120
    • Trivedi, P.S.1    Tray, N.J.2    Nguyen, T.D.3    Nigam, N.4    Gallicano, G.I.5
  • 37
    • 33847656206 scopus 로고    scopus 로고
    • Transplantation of human undifferentiated embryonic stem cells into a myocardial infarction rat model
    • Xie, C. Q., Zhang, J., Xiao, Y., Zhang, L., Mou, Y., Liu, X., Akinbami, M., Cui, T., and Chen, Y. E. (2007). Transplantation of human undifferentiated embryonic stem cells into a myocardial infarction rat model. Stem Cells Dev 16, 25-29.
    • (2007) Stem Cells Dev , vol.16 , pp. 25-29
    • Xie, C.Q.1    Zhang, J.2    Xiao, Y.3    Zhang, L.4    Mou, Y.5    Liu, X.6    Akinbami, M.7    Cui, T.8    Chen, Y.E.9
  • 38
    • 38149111737 scopus 로고    scopus 로고
    • Lovastatin protects mesenchymal stem cells against hypoxia- and serum deprivation-induced apoptosis by activation of PI3K/Akt and ERK1/2
    • Xu, R., Chen, J., Cong, X., Hu, S., and Chen, X. (2008). Lovastatin protects mesenchymal stem cells against hypoxia- and serum deprivation-induced apoptosis by activation of PI3K/Akt and ERK1/2. J Cell Biochem 103, 256-269.
    • (2008) J Cell Biochem , vol.103 , pp. 256-269
    • Xu, R.1    Chen, J.2    Cong, X.3    Hu, S.4    Chen, X.5
  • 39
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
    • Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T. I., Jones, D. P., and Wang, X. (1997). Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275, 1129-1132.
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4    Ibrado, A.M.5    Cai, J.6    Peng, T.I.7    Jones, D.P.8    Wang, X.9
  • 40
    • 77952675373 scopus 로고    scopus 로고
    • Netrin-1 prevents ischemia/reperfusion-induced myocardial infarction via a DCC/ERK1/2/eNOS (s1177)/NO/DCC feed-forward mechanism
    • Zhang, J., and Cai, H. (2010). Netrin-1 prevents ischemia/reperfusion-induced myocardial infarction via a DCC/ERK1/2/eNOS (s1177)/NO/DCC feed-forward mechanism. J Mol Cell Cardiol 48, 1060-1070.
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 1060-1070
    • Zhang, J.1    Cai, H.2
  • 41
    • 35248875838 scopus 로고    scopus 로고
    • SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction
    • Zhang, M., Mal, N., Kiedrowski, M., Chacko, M., Askari, A. T., Popovic, Z. B., Koc, O. N., and Penn, M. S. (2007). SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction. FASEB J 21, 3197-3207.
    • (2007) FASEB J , vol.21 , pp. 3197-3207
    • Zhang, M.1    Mal, N.2    Kiedrowski, M.3    Chacko, M.4    Askari, A.T.5    Popovic, Z.B.6    Koc, O.N.7    Penn, M.S.8


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