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Volumn 17, Issue 4, 2008, Pages 725-736

Fibroblast growth factor-2 and -4 promote the proliferation of bone marrow mesenchymal stem cells by the activation of the PI3K-Akt and ERK1/2 signaling pathways

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; BROXURIDINE; CYTOKINE; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 4; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C JUN; PROTEIN KINASE B; STAT3 PROTEIN; STEM CELL ANTIGEN 1;

EID: 51849111566     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2007.0230     Document Type: Article
Times cited : (110)

References (68)
  • 2
    • 37649026269 scopus 로고    scopus 로고
    • Adult bone marrow stem cells for cell and gene therapies: Implications for greater use
    • Ballas CB, SP Zielske and SL Gerson. (2002). Adult bone marrow stem cells for cell and gene therapies: implications for greater use. J Cell Biochem Suppl 200;38:20-28.
    • (2002) J Cell Biochem , vol.38 , Issue.SUPPL. 200 , pp. 20-28
    • Ballas, C.B.1    Zielske, S.P.2    Gerson, S.L.3
  • 4
    • 1842411942 scopus 로고
    • Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family
    • van de Rijn M, S Heimfeld, GJ Spangrude and IL Weissman. (1989). Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family. Proc Natl Acad Sci USA 86:4634-4638.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 4634-4638
    • van de Rijn, M.1    Heimfeld, S.2    Spangrude, G.J.3    Weissman, I.L.4
  • 6
    • 0038487656 scopus 로고    scopus 로고
    • In vivo cardiovasculogenesis by direct injection of isolated adult mesenchymal stem cells
    • Gojo S, N Gojo, Y Takeda, T Mori, H Abe, S Kyo, J Hata and A Umezawa. (2003). In vivo cardiovasculogenesis by direct injection of isolated adult mesenchymal stem cells. Exp Cell Res 288:51-59.
    • (2003) Exp Cell Res , vol.288 , pp. 51-59
    • Gojo, S.1    Gojo, N.2    Takeda, Y.3    Mori, T.4    Abe, H.5    Kyo, S.6    Hata, J.7    Umezawa, A.8
  • 8
    • 18844424692 scopus 로고    scopus 로고
    • Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue
    • Burger PE, X Xiong, S Coetzee, SN Salm, D Moscatelli, K Goto and EL Wilson. (2005). Sca-1 expression identifies stem cells in the proximal region of prostatic ducts with high capacity to reconstitute prostatic tissue. Proc Natl Acad Sci USA 102:7180-7185.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 7180-7185
    • Burger, P.E.1    Xiong, X.2    Coetzee, S.3    Salm, S.N.4    Moscatelli, D.5    Goto, K.6    Wilson, E.L.7
  • 9
    • 0037609723 scopus 로고    scopus 로고
    • Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice
    • Bonyadi M, SD Waldman, D Liu, JE Aubin, MD Grynpas and WL Stanford. (2003). Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice. Proc Natl Acad Sci USA 100:5840-5845.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5840-5845
    • Bonyadi, M.1    Waldman, S.D.2    Liu, D.3    Aubin, J.E.4    Grynpas, M.D.5    Stanford, W.L.6
  • 10
    • 36049044846 scopus 로고    scopus 로고
    • Longitudinal analysis of mesenchymal progenitors and bone quality in the stem cell antigen-1-null osteoporotic mouse
    • Holmes C, TS Khan, C Owen, N Ciliberti, MD Grynpas and WL Stanford. (2007). Longitudinal analysis of mesenchymal progenitors and bone quality in the stem cell antigen-1-null osteoporotic mouse. J Bone Miner Res 22:1373-1386.
    • (2007) J Bone Miner Res , vol.22 , pp. 1373-1386
    • Holmes, C.1    Khan, T.S.2    Owen, C.3    Ciliberti, N.4    Grynpas, M.D.5    Stanford, W.L.6
  • 14
    • 0029930911 scopus 로고    scopus 로고
    • In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain
    • Craig CG, V Tropepe, CM Morshead, BA Reynolds, S Weiss and D van der Kooy. (1996). In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain. J Neurosci 16:2649-2658.
    • (1996) J Neurosci , vol.16 , pp. 2649-2658
    • Craig, C.G.1    Tropepe, V.2    Morshead, C.M.3    Reynolds, B.A.4    Weiss, S.5    van der Kooy, D.6
  • 15
    • 0030042746 scopus 로고    scopus 로고
    • Effects of fibroblast growth factor-4 (k-FGF) on long-term cultures of human bone marrow cells
    • Quito FL, J Beh, O Bashayan, C Basilico and RS Basch. Effects of fibroblast growth factor-4 (k-FGF) on long-term cultures of human bone marrow cells. Blood 1996;87:1282-1291.
    • (1996) Blood , vol.87 , pp. 1282-1291
    • Quito, F.L.1    Beh, J.2    Bashayan, O.3    Basilico, C.4    Basch, R.S.5
  • 16
    • 0344848564 scopus 로고    scopus 로고
    • Gritti A, P Frolichsthal-Schoeller, R Galli, EA Parati, L Cova, SF Pagano, CR Bjornson and AL Vescovi. (1999). Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain. J Neurosci 19:328703297.
    • Gritti A, P Frolichsthal-Schoeller, R Galli, EA Parati, L Cova, SF Pagano, CR Bjornson and AL Vescovi. (1999). Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain. J Neurosci 19:328703297.
  • 18
    • 20444375784 scopus 로고    scopus 로고
    • Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development
    • Wang L, L Li, P Menendez, C Cerdan and M Bhatia. (2005). Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development. Blood 105:4598-4603.
    • (2005) Blood , vol.105 , pp. 4598-4603
    • Wang, L.1    Li, L.2    Menendez, P.3    Cerdan, C.4    Bhatia, M.5
  • 19
    • 33747616838 scopus 로고    scopus 로고
    • Fibroblast growth factor-1 and -2 preserve long-term repopulating ability of hematopoietic stem cells in serum-free cultures
    • Yeoh JS, R van Os, E Weersing, A Ausema, B Dontje, E Vellenga and G de Haan. (2006). Fibroblast growth factor-1 and -2 preserve long-term repopulating ability of hematopoietic stem cells in serum-free cultures. Stem Cells 24:1564-1572.
    • (2006) Stem Cells , vol.24 , pp. 1564-1572
    • Yeoh, J.S.1    van Os, R.2    Weersing, E.3    Ausema, A.4    Dontje, B.5    Vellenga, E.6    de Haan, G.7
  • 20
    • 33846040847 scopus 로고    scopus 로고
    • Fibroblast growth factors as regulators of stem cell self-renewal and aging
    • Yeoh JS and G de Haan. (2007). Fibroblast growth factors as regulators of stem cell self-renewal and aging. Mech Ageing Dev 128:17-24.
    • (2007) Mech Ageing Dev , vol.128 , pp. 17-24
    • Yeoh, J.S.1    de Haan, G.2
  • 22
    • 0043071544 scopus 로고    scopus 로고
    • Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection
    • Baddoo M, K Hill, R Wilkinson, D Gaupp, C Hughes, GC Kopen and DG Phinney. (2003). Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection. J Cell Biochem 89:1235-1249.
    • (2003) J Cell Biochem , vol.89 , pp. 1235-1249
    • Baddoo, M.1    Hill, K.2    Wilkinson, R.3    Gaupp, D.4    Hughes, C.5    Kopen, G.C.6    Phinney, D.G.7
  • 23
    • 16344377055 scopus 로고    scopus 로고
    • FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells
    • Solchaga LA, K Penick, JD Porter, VM Goldberg, AI Caplan and JF Welter. (2005). FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells. J Cell Physiol 203:398-409.
    • (2005) J Cell Physiol , vol.203 , pp. 398-409
    • Solchaga, L.A.1    Penick, K.2    Porter, J.D.3    Goldberg, V.M.4    Caplan, A.I.5    Welter, J.F.6
  • 24
    • 33645130153 scopus 로고    scopus 로고
    • Mitogenic and chondrogenic effects of fibroblast growth factor-2 in adipose-derived mesenchymal cells
    • Chiou M, Y Xu and MT Longaker. (2006). Mitogenic and chondrogenic effects of fibroblast growth factor-2 in adipose-derived mesenchymal cells. Biochem Biophys Res Commun 343:644-652.
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 644-652
    • Chiou, M.1    Xu, Y.2    Longaker, M.T.3
  • 25
    • 34447130140 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling
    • Cohen ED, Z Wang, JJ Lepore, MM Lu, MM Taketo, DJ Epstein and EE Morrisey. (2007). Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling. J Clin Invest 117:1794-1804.
    • (2007) J Clin Invest , vol.117 , pp. 1794-1804
    • Cohen, E.D.1    Wang, Z.2    Lepore, J.J.3    Lu, M.M.4    Taketo, M.M.5    Epstein, D.J.6    Morrisey, E.E.7
  • 26
    • 34249661093 scopus 로고    scopus 로고
    • FGF-2 suppresses cellular senescence of human mesenchymal stem cells by down-regulation of TGF-beta2
    • Ito T, R Sawada, Y Fujiwara, Y Seyama and T Tsuchiya. (2007). FGF-2 suppresses cellular senescence of human mesenchymal stem cells by down-regulation of TGF-beta2. Biochem Biophys Res Commun 359:108-114.
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 108-114
    • Ito, T.1    Sawada, R.2    Fujiwara, Y.3    Seyama, Y.4    Tsuchiya, T.5
  • 27
    • 33746846927 scopus 로고    scopus 로고
    • FGF-2 inhibits osteogenesis in mouse adipose tissue-derived stromal cells and sustains their proliferative and osteogenic potential state
    • Quarto N and MT Longaker. (2006). FGF-2 inhibits osteogenesis in mouse adipose tissue-derived stromal cells and sustains their proliferative and osteogenic potential state. Tissue Eng 12:1405-1418.
    • (2006) Tissue Eng , vol.12 , pp. 1405-1418
    • Quarto, N.1    Longaker, M.T.2
  • 30
    • 0030706168 scopus 로고    scopus 로고
    • A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/ MAPK signaling pathway
    • Kouhara H, YR Hadari, T Spivak-Kroizman, J Schilling, D Bar-Sagi, I Lax and J Schlessinger. (1997). A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/ MAPK signaling pathway. Cell 89:693-702.
    • (1997) Cell , vol.89 , pp. 693-702
    • Kouhara, H.1    Hadari, Y.R.2    Spivak-Kroizman, T.3    Schilling, J.4    Bar-Sagi, D.5    Lax, I.6    Schlessinger, J.7
  • 31
    • 9444287030 scopus 로고    scopus 로고
    • Common and distinct elements in cellular signaling via EGF and FGF receptors
    • Schlessinger J. (2004).Common and distinct elements in cellular signaling via EGF and FGF receptors. Science 306:1506-1507.
    • (2004) Science , vol.306 , pp. 1506-1507
    • Schlessinger, J.1
  • 32
    • 33646551808 scopus 로고    scopus 로고
    • Fibroblast growth factor signaling in embryonic and cancer stem cells
    • Dvorak P, D Dvorakova and A Hampl. (2006). Fibroblast growth factor signaling in embryonic and cancer stem cells. FEBS Lett 580:2869-2874.
    • (2006) FEBS Lett , vol.580 , pp. 2869-2874
    • Dvorak, P.1    Dvorakova, D.2    Hampl, A.3
  • 33
    • 0028170641 scopus 로고
    • Serum-regulated transcription by serum response factor (SRF): A novel role for the DNA binding domain
    • Hill CS, J Wynne and R Treisman. (1994). Serum-regulated transcription by serum response factor (SRF): a novel role for the DNA binding domain. EMBO J 13:5421-5432.
    • (1994) EMBO J , vol.13 , pp. 5421-5432
    • Hill, C.S.1    Wynne, J.2    Treisman, R.3
  • 34
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L and M Karin. (2001). Mammalian MAP kinase signalling cascades. Nature 410:37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 35
    • 0035971493 scopus 로고    scopus 로고
    • AP-1 in cell proliferation and survival
    • Shaulian E and M Karin. (2001). AP-1 in cell proliferation and survival. Oncogene 20:2390-2400.
    • (2001) Oncogene , vol.20 , pp. 2390-2400
    • Shaulian, E.1    Karin, M.2
  • 36
    • 0036098552 scopus 로고    scopus 로고
    • AP-1 as a regulator of cell life and death
    • Shaulian E and M Karin. (2002). AP-1 as a regulator of cell life and death. Nat Cell Biol 4(5):E131-136.
    • (2002) Nat Cell Biol , vol.4 , Issue.5
    • Shaulian, E.1    Karin, M.2
  • 38
    • 1842486565 scopus 로고    scopus 로고
    • Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms
    • Kinnaird T, E Stabile, MS Burnett, M Shou, CW Lee, S Barr, S Fuchs and SE Epstein. (2004). Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms. Circulation 109:1543-1549.
    • (2004) Circulation , vol.109 , pp. 1543-1549
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3    Shou, M.4    Lee, C.W.5    Barr, S.6    Fuchs, S.7    Epstein, S.E.8
  • 39
    • 26844551297 scopus 로고    scopus 로고
    • Transdifferentiation of mesenchymal stem cells into cardiomyocytes by direct cell-to-cell contact with neonatal cardiomyocyte but not adult cardiomyocytes
    • Yoon J, WJ Shim, YM Ro and DS Lim. (2005). Transdifferentiation of mesenchymal stem cells into cardiomyocytes by direct cell-to-cell contact with neonatal cardiomyocyte but not adult cardiomyocytes. Ann Hematol 84:715-721.
    • (2005) Ann Hematol , vol.84 , pp. 715-721
    • Yoon, J.1    Shim, W.J.2    Ro, Y.M.3    Lim, D.S.4
  • 40
    • 12344252237 scopus 로고    scopus 로고
    • AP-1 subunits: Quarrel and harmony among siblings
    • Hess J, P Angel and M Schorpp-Kistner. (2004). AP-1 subunits: quarrel and harmony among siblings. J Cell Sci 117:5965-5973.
    • (2004) J Cell Sci , vol.117 , pp. 5965-5973
    • Hess, J.1    Angel, P.2    Schorpp-Kistner, M.3
  • 41
    • 33748145149 scopus 로고    scopus 로고
    • Mechanism of transcriptional activation by the Myc oncoproteins
    • Cowling VH and MD Cole. (2006). Mechanism of transcriptional activation by the Myc oncoproteins. Semin Cancer Biol 16:242-252.
    • (2006) Semin Cancer Biol , vol.16 , pp. 242-252
    • Cowling, V.H.1    Cole, M.D.2
  • 42
    • 34248597065 scopus 로고    scopus 로고
    • Differential regulation and properties of MAPKs
    • Raman M, W Chen and MH Cobb. (2007). Differential regulation and properties of MAPKs. Oncogene 26:3100-3112.
    • (2007) Oncogene , vol.26 , pp. 3100-3112
    • Raman, M.1    Chen, W.2    Cobb, M.H.3
  • 44
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury D, EJ Schwarz, DJ Prockop and IB Black. (2000). Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 61:364-370.
    • (2000) J Neurosci Res , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 45
    • 0034805960 scopus 로고    scopus 로고
    • MicroSAGE analysis of 2,353 expressed genes in a single cell-derived colony of undifferentiated human mesenchymal stem cells reveals mRNAs of multiple cell lineages
    • Tremain N, J Korkko, D Ibberson, GC Kopen, C DiGirolamo and DG Phinney. (2001). MicroSAGE analysis of 2,353 expressed genes in a single cell-derived colony of undifferentiated human mesenchymal stem cells reveals mRNAs of multiple cell lineages. Stem Cells 19:408-418.
    • (2001) Stem Cells , vol.19 , pp. 408-418
    • Tremain, N.1    Korkko, J.2    Ibberson, D.3    Kopen, G.C.4    DiGirolamo, C.5    Phinney, D.G.6
  • 46
    • 0141796313 scopus 로고    scopus 로고
    • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
    • Mangi AA, N Noiseux, D Kong, H He, M Rezvani, JS Ingwall and VJ Dzau. (2003). Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med 9:1195-1201.
    • (2003) Nat Med , vol.9 , pp. 1195-1201
    • Mangi, A.A.1    Noiseux, N.2    Kong, D.3    He, H.4    Rezvani, M.5    Ingwall, J.S.6    Dzau, V.J.7
  • 47
    • 0037078327 scopus 로고    scopus 로고
    • Myogenic specification of side population cells in skeletal muscle
    • Asakura A, P Seale, A Girgis-Gabardo and MA Rudnicki. (2002). Myogenic specification of side population cells in skeletal muscle. J Cell Biol 159:123-134.
    • (2002) J Cell Biol , vol.159 , pp. 123-134
    • Asakura, A.1    Seale, P.2    Girgis-Gabardo, A.3    Rudnicki, M.A.4
  • 49
    • 0036754547 scopus 로고    scopus 로고
    • Current understanding of stem cell mobilization: The roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells
    • Lapidot T and I Petit. (2002). Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp Hematol 30:973-981.
    • (2002) Exp Hematol , vol.30 , pp. 973-981
    • Lapidot, T.1    Petit, I.2
  • 50
    • 0036254775 scopus 로고    scopus 로고
    • Cytokine and chemokine networks influencing stem cell proliferation, differentiation, and marrow homing
    • Moore MA. (2002). Cytokine and chemokine networks influencing stem cell proliferation, differentiation, and marrow homing. J Cell Biochem Suppl 38:29-38.
    • (2002) J Cell Biochem , Issue.SUPPL. 38 , pp. 29-38
    • Moore, M.A.1
  • 51
    • 33749502961 scopus 로고    scopus 로고
    • Cytokines and hematopoietic stem cell mobilization
    • Nervi B, DC Link and JF DiPersio. (2006). Cytokines and hematopoietic stem cell mobilization. J Cell Biochem 99:690-705.
    • (2006) J Cell Biochem , vol.99 , pp. 690-705
    • Nervi, B.1    Link, D.C.2    DiPersio, J.F.3
  • 52
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: Navigating downstream
    • Manning BD and LC Cantley. (2007). AKT/PKB signaling: navigating downstream. Cell 129:1261-1274.
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 53
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, A Brunet and ME Greenberg. (1999). Cellular survival: a play in three Akts. Genes Dev 13:2905-2927.
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 54
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4- one (LY294002)
    • Vlahos CJ, WF Matter, KY Hui and RF Brown. (1994). A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4- one (LY294002). J Biol Chem 269:5241-5248.
    • (1994) J Biol Chem , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 55
    • 0034734123 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase kinase blocks proliferation of neural progenitor cells
    • Learish RD, MD Bruss and M Haak-Frendscho. (2000). Inhibition of mitogen-activated protein kinase kinase blocks proliferation of neural progenitor cells. Brain Res Dev Brain Res 122:97-109.
    • (2000) Brain Res Dev Brain Res , vol.122 , pp. 97-109
    • Learish, R.D.1    Bruss, M.D.2    Haak-Frendscho, M.3
  • 56
    • 20144363322 scopus 로고    scopus 로고
    • NT3 inhibits FGF2-induced neural progenitor cell proliferation via the PI3K/GSK3 pathway
    • Jin L, X Hu and L Feng. (2005). NT3 inhibits FGF2-induced neural progenitor cell proliferation via the PI3K/GSK3 pathway. J Neurochem 93:1251-1261.
    • (2005) J Neurochem , vol.93 , pp. 1251-1261
    • Jin, L.1    Hu, X.2    Feng, L.3
  • 57
    • 33750565706 scopus 로고    scopus 로고
    • Autocrine fibroblast growth factor 2 signaling is critical for self-renewal of human multipotent adipose-derived stem cells
    • Zaragosi LE, G Ailhaud and C Dani. (2006). Autocrine fibroblast growth factor 2 signaling is critical for self-renewal of human multipotent adipose-derived stem cells. Stem Cells 24:2412-2419.
    • (2006) Stem Cells , vol.24 , pp. 2412-2419
    • Zaragosi, L.E.1    Ailhaud, G.2    Dani, C.3
  • 58
    • 33847653790 scopus 로고    scopus 로고
    • Fibroblast growth factors 2, 4, and 8 exert both negative and positive effects on limb, frontonasal, and mandibular chondrogenesis via MEK-ERK activation
    • Bobick BE, TM Thornhill and WM Kulyk. (2007). Fibroblast growth factors 2, 4, and 8 exert both negative and positive effects on limb, frontonasal, and mandibular chondrogenesis via MEK-ERK activation. J Cell Physiol 211:233-243.
    • (2007) J Cell Physiol , vol.211 , pp. 233-243
    • Bobick, B.E.1    Thornhill, T.M.2    Kulyk, W.M.3
  • 59
    • 0029032249 scopus 로고
    • The regulation of AP-1 activity by mitogen-activated protein kinases
    • Karin M. (1995). The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270:16483-16486.
    • (1995) J Biol Chem , vol.270 , pp. 16483-16486
    • Karin, M.1
  • 61
    • 24144495196 scopus 로고    scopus 로고
    • Basic fibroblast growth factor activates ERK and induces c-fos in human embryonic stem cell line MizhES1
    • Kang HB, JS Kim, HJ Kwon, KH Nam, HS Youn, DE Sok and Y Lee. (2005). Basic fibroblast growth factor activates ERK and induces c-fos in human embryonic stem cell line MizhES1. Stem Cells Dev 14:395-401.
    • (2005) Stem Cells Dev , vol.14 , pp. 395-401
    • Kang, H.B.1    Kim, J.S.2    Kwon, H.J.3    Nam, K.H.4    Youn, H.S.5    Sok, D.E.6    Lee, Y.7
  • 64
    • 0024276523 scopus 로고
    • The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1
    • Angel P, K Hattori, T Smeal and M Karin. (1988). The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1. Cell 55:875-885.
    • (1988) Cell , vol.55 , pp. 875-885
    • Angel, P.1    Hattori, K.2    Smeal, T.3    Karin, M.4
  • 65
    • 0033607784 scopus 로고    scopus 로고
    • Rommel C, BA Clarke, S Zimmermann, L Nunez, R Rossman, K Reid, K Moelling, GD Yancopoulos and DJ Glass. (1999). Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. Science 286:1738-1741.
    • Rommel C, BA Clarke, S Zimmermann, L Nunez, R Rossman, K Reid, K Moelling, GD Yancopoulos and DJ Glass. (1999). Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. Science 286:1738-1741.
  • 66
    • 0033607633 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Raf by Akt (protein kinase B)
    • Zimmermann S and K Moelling. (1999). Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 286:1741-1744.
    • (1999) Science , vol.286 , pp. 1741-1744
    • Zimmermann, S.1    Moelling, K.2
  • 67
    • 0035133227 scopus 로고    scopus 로고
    • Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
    • Kim AH, G Khursigara, X Sun, TF Franke and MV Chao. (2001). Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol 21:893-901.
    • (2001) Mol Cell Biol , vol.21 , pp. 893-901
    • Kim, A.H.1    Khursigara, G.2    Sun, X.3    Franke, T.F.4    Chao, M.V.5
  • 68
    • 0037077235 scopus 로고    scopus 로고
    • Phosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human umbilical vein endothelial cells. Evidence for a dual kinase mechanism
    • Deo DD, TW Axelrad, EG Robert, V Marcheselli, NG Bazan and JD Hunt. (2002). Phosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human umbilical vein endothelial cells. Evidence for a dual kinase mechanism. J Biol Chem 277:21237-21245.
    • (2002) J Biol Chem , vol.277 , pp. 21237-21245
    • Deo, D.D.1    Axelrad, T.W.2    Robert, E.G.3    Marcheselli, V.4    Bazan, N.G.5    Hunt, J.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.