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Volumn 32, Issue 1-2, 2010, Pages 49-61

Triple-negative breast cancers and the human mammary epithelial cell hierarchy

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; ALPHA6 INTEGRIN; BETA1 INTEGRIN; BRCA1 PROTEIN; BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; CD24 ANTIGEN; CLAUDIN 3; CLAUDIN 4; CLAUDIN 7; CYTOKERATIN 15; CYTOKERATIN 5; CYTOKERATIN 6; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITHELIAL CELL ADHESION MOLECULE; ESTROGEN RECEPTOR; GLYCOPROTEIN P; HERMES ANTIGEN; MUCIN 1; PROGESTERONE RECEPTOR; PROTEIN BCL 2; STAGE SPECIFIC EMBRYO ANTIGEN 4; UVOMORULIN;

EID: 80755169604     PISSN: 08886008     EISSN: 15581551     Source Type: Journal    
DOI: 10.3233/BD-2010-0322     Document Type: Article
Times cited : (2)

References (114)
  • 1
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • DOI 10.1038/ng.127, PII NG127
    • I. Ben-Porath et al., An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors, Nat Genet 40 (2008), 499-507. (Pubitemid 351601215)
    • (2008) Nature Genetics , vol.40 , Issue.5 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 2
    • 67849085497 scopus 로고    scopus 로고
    • Breast cancer stem cells and intrinsic subtypes: Controversies rage on
    • H. Nakshatri, E.F. Srour and S. Badve, Breast cancer stem cells and intrinsic subtypes: controversies rage on, Curr Stem Cell Res Ther 4 (2009), 50-60.
    • (2009) Curr. Stem. Cell Res. Ther. , vol.4 , pp. 50-60
    • Nakshatri, H.1    Srour, E.F.2    Badve, S.3
  • 3
    • 76049114936 scopus 로고    scopus 로고
    • Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer
    • S.Y. Park et al., Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer, Clin Cancer Res 16 (2010), 876-887.
    • (2010) Clin. Cancer Res. , vol.16 , pp. 876-887
    • Park, S.Y.1
  • 4
    • 0027285213 scopus 로고
    • Epithelial stem cells and their possible role in the development of the normal and diseased human breast
    • P.S. Rudland, Epithelial stem cells and their possible role in the development of the normal and diseased human breast, Histol Histopathol 8 (1993), 385-404. (Pubitemid 23125715)
    • (1993) Histology and Histopathology , vol.8 , Issue.2 , pp. 385-404
    • Rudland, P.S.1
  • 6
    • 36248953716 scopus 로고    scopus 로고
    • Mammary stem cells and breast cancer - Role of notch signalling
    • DOI 10.1007/s12015-007-0023-5, PII SCR32169
    • G. Farnie and R.B. Clarke, Mammary stem cells and breast cancer-role of Notch signalling, Stem Cell Rev 3 (2007), 169-175. (Pubitemid 350129719)
    • (2007) Stem Cell Reviews , vol.3 , Issue.2 , pp. 169-175
    • Farnie, G.1    Clarke, R.B.2
  • 7
    • 74249083841 scopus 로고    scopus 로고
    • Triple negative breast carcinomas: Similarities and differences with basal like carcinomas
    • E. Lerma, A. Barnadas and J. Prat, Triple negative breast carcinomas: similarities and differences with basal like carcinomas, Appl Immunohistochem Mol Morphol 17 (2009), 483-494.
    • (2009) Appl. Immunohistochem. Mol. Morphol. , vol.17 , pp. 483-494
    • Lerma, E.1    Barnadas, A.2    Prat, J.3
  • 8
    • 77953863072 scopus 로고    scopus 로고
    • Triple negative breast cancer: From molecular portrait to therapeutic intervention
    • P. Carotenuto et al., Triple negative breast cancer: from molecular portrait to therapeutic intervention, Crit Rev Eukaryot Gene Expr 20 (2010), 17-34.
    • (2010) Crit. Rev. Eukaryot. Gene Expr. , vol.20 , pp. 17-34
    • Carotenuto, P.1
  • 9
    • 73949139019 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Clinicopathological characteristics and relationship with basal-like breast cancer
    • A.A. Thike et al., Triple-negative breast cancer: clinicopathological characteristics and relationship with basal-like breast cancer, Mod Pathol 23 (2010), 123-133.
    • (2010) Mod. Pathol. , vol.23 , pp. 123-133
    • Thike, A.A.1
  • 11
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumours
    • C.M. Perou et al., Molecular portraits of human breast tumours, Nature 406 (2000), 747-752.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1
  • 14
    • 37549020704 scopus 로고    scopus 로고
    • Recurrent grossmutations of the PTENtumor suppressor gene in breast cancers with deficient DSB repair
    • L.H. Saal et al., Recurrent grossmutations of the PTENtumor suppressor gene in breast cancers with deficient DSB repair, Nat Genet 40 (2008), 102-107.
    • (2008) Nat. Genet. , vol.40 , pp. 102-107
    • Saal, L.H.1
  • 15
    • 63849329936 scopus 로고    scopus 로고
    • Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells
    • B. Marty et al., Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells, Breast Cancer Res 10 (2008), R101.
    • (2008) Breast Cancer Res. , vol.10
    • Marty, B.1
  • 16
    • 58349094961 scopus 로고    scopus 로고
    • High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors
    • E. Manie et al., High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors, Cancer Res 69 (2009), 663-671.
    • (2009) Cancer Res. , vol.69 , pp. 663-671
    • Manie, E.1
  • 17
    • 34250760957 scopus 로고    scopus 로고
    • TP53mutation status and gene expression profiles are powerful prognostic markers of breast cancer
    • A. Langerod et al., TP53mutation status and gene expression profiles are powerful prognostic markers of breast cancer, Breast Cancer Res 9 (2007), R30.
    • (2007) Breast Cancer Res. , vol.9
    • Langerod, A.1
  • 19
    • 67650688104 scopus 로고    scopus 로고
    • Themajority of triple-negative breast cancer may correspond to basal-like carcinoma but triple-negative breast cancer is not identical to basal-like carcinoma
    • N.Kuroda et al., Themajority of triple-negative breast cancer may correspond to basal-like carcinoma, but triple-negative breast cancer is not identical to basal-like carcinoma, Med Mol Morphol 42 (2009), 128-131.
    • (2009) Med. Mol. Morphol. , vol.42 , pp. 128-131
    • Kuroda, N.1
  • 21
    • 67650498979 scopus 로고    scopus 로고
    • Triple negative breast cancer: A study from the point of view of basal CK5/6 and HER-1
    • S. Pintens et al., Triple negative breast cancer: a study from the point of view of basal CK5/6 and HER-1, J Clin Pathol 62 (2009), 624-628.
    • (2009) J. Clin. Pathol. , vol.62 , pp. 624-628
    • Pintens, S.1
  • 25
    • 67650252530 scopus 로고    scopus 로고
    • Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery
    • J. Kao et al., Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery, PLoS One 4 (2009), e6146.
    • (2009) PLoS One , vol.4
    • Kao, J.1
  • 26
    • 31044441241 scopus 로고    scopus 로고
    • Gene expression profiling of breast cell lines identifies potential new basal markers
    • E. Charafe-Jauffret et al., Gene expression profiling of breast cell lines identifies potential new basal markers, Oncogene 25 (2006), 2273-2284.
    • (2006) Oncogene , vol.25 , pp. 2273-2284
    • Charafe-Jauffret, E.1
  • 27
    • 65249104546 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Distinguishing between basal and nonbasal subtypes
    • E.A. Rakha et al., Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes, Clin Cancer Res 15 (2009), 2302-2310.
    • (2009) Clin Cancer Res. , vol.15 , pp. 2302-2310
    • Rakha, E.A.1
  • 28
    • 78049308800 scopus 로고    scopus 로고
    • Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
    • A. Prat et al., Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer, Breast Cancer Res 12 (2010), R68.
    • (2010) Breast Cancer Res. , vol.12
    • Prat, A.1
  • 29
    • 34548863946 scopus 로고    scopus 로고
    • Identification of conserved gene expression features between murinemammary carcinoma models and human breast tumors
    • J.I. Herschkowitz et al., Identification of conserved gene expression features between murinemammary carcinoma models and human breast tumors, Genome Biol 8 (2007), R76.
    • (2007) Genome Biol. , vol.8
    • Herschkowitz, J.I.1
  • 30
    • 77957262381 scopus 로고    scopus 로고
    • Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes
    • U S A
    • J.H. Taube et al., Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes, Proc Natl Acad Sci U S A 107 (2010), 15449-15454.
    • (2010) Proc. Natl. Acad. Sci. , vol.107 , pp. 15449-15454
    • Taube, J.H.1
  • 31
    • 68949136025 scopus 로고    scopus 로고
    • Metaplastic breast carcinomas are basal-like breast cancers: A genomic profiling analysis
    • B. Weigelt B. Kreike and J.S. Reis-Filho, Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis, Breast Cancer Res Treat 117 (2009), 273-280.
    • (2009) Breast. Cancer Res. Treat. , vol.117 , pp. 273-280
    • Weigelt, B.1    Kreike, B.2    Reis-Filho, J.S.3
  • 33
    • 77957947579 scopus 로고    scopus 로고
    • Adenoid cystic carcinomas of the breast have low Topo IIalpha expression but frequently overexpress EGFR protein without EGFR gene amplification
    • S. Vranic et al., Adenoid cystic carcinomas of the breast have low Topo IIalpha expression but frequently overexpress EGFR protein without EGFR gene amplification, Hum Pathol, (2010).
    • (2010) Hum. Pathol.
    • Vranic, S.1
  • 34
    • 77749295010 scopus 로고    scopus 로고
    • Adenoid cystic carcinomas of the breast and salivary glands or the strange case of dr jekyll and mr hyde' of exocrine gland carcinomas
    • C. Marchio, B. Weigelt and J.S. Reis-Filho, Adenoid cystic carcinomas of the breast and salivary glands (or 'The strange case of Dr Jekyll and Mr Hyde' of exocrine gland carcinomas), J Clin Pathol 63 (2010), 220-228.
    • (2010) J. Clin. Pathol. , vol.63 , pp. 220-228
    • Marchio, C.1    Weigelt, B.2    Reis-Filho, J.S.3
  • 35
    • 72749103664 scopus 로고    scopus 로고
    • Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis
    • J.E. Visvader, Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis, Genes Dev 23 (2009), 2563-2577.
    • (2009) Genes Dev. , vol.23 , pp. 2563-2577
    • Visvader, J.E.1
  • 38
    • 0030059759 scopus 로고    scopus 로고
    • Contiguous patches of normal human mammary epithelium derived from a single stem cell: Implications for breast carcinogenesis
    • Y.C. Tsai et al., Contiguous patches of normal human mammary epithelium derived from a single stemcell: implications for breast carcinogenesis, Cancer Res 56 (1996), 402-404. (Pubitemid 26026371)
    • (1996) Cancer Research , vol.56 , Issue.2 , pp. 402-404
    • Tsai, Y.C.1    Lu, Y.2    Nichols, P.W.3    Zlotnikov, G.4    Jones, P.S.5    Smith, H.S.6
  • 41
    • 36248974147 scopus 로고    scopus 로고
    • Prospective isolation and functional analysis of stem and differentiated cells from the mouse mammary gland
    • DOI 10.1007/s12015-007-0017-3, PII SCR32124
    • J. Regan and M. Smalley, Prospective isolation and functional analysis of stem and differentiated cells from the mouse mammary gland, Stem Cell Rev 3 (2007), 124-136. (Pubitemid 350129715)
    • (2007) Stem Cell Reviews , vol.3 , Issue.2 , pp. 124-136
    • Regan, J.1    Smalley, M.2
  • 42
    • 68549119126 scopus 로고    scopus 로고
    • Delineating the epithelial hierarchy in themousemammary gland
    • M.L.Asselin-Labat et al., Delineating the epithelial hierarchy in themousemammary gland, Cold SpringHarb SympQuant Biol 73 (2008), 469-478.
    • (2008) Cold Spring. Harb. Symp. Quant. Biol. , vol.73 , pp. 469-478
    • Asselin-Labat, M.L.1
  • 44
    • 67650723731 scopus 로고    scopus 로고
    • Breast cancer stem cells: Tools and models to rely on
    • E. Charafe-Jauffret, C. Ginestier and D. Birnbaum, Breast cancer stem cells: tools and models to rely on, BMC Cancer 9 (2009), 202.
    • (2009) BMC Cancer , vol.9 , pp. 202
    • Charafe-Jauffret, E.1    Ginestier, C.2    Birnbaum, D.3
  • 45
    • 77449153402 scopus 로고    scopus 로고
    • Its all in the details: Methods in breast development and cancer
    • M. Bentires-Alj et al., It's all in the details: methods in breast development and cancer, Breast Cancer Res 11 (2009), 305.
    • (2009) Breast Cancer Res. , vol.11 , pp. 305
    • Bentires-Alj, M.1
  • 46
    • 58449087260 scopus 로고    scopus 로고
    • Detection and analysis of mammary gland stem cells
    • J. Stingl, Detection and analysis of mammary gland stem cells, J Pathol 217 (2009), 229-241.
    • (2009) J. Pathol. , vol.217 , pp. 229-241
    • Stingl, J.1
  • 47
    • 16644364791 scopus 로고    scopus 로고
    • Enzymatic dissociation and culture of normal human mammary tissue to detect progenitor activity
    • J. Stingl, J.T. Emerman and C.J. Eaves, Enzymatic dissociation and culture of normal human mammary tissue to detect progenitor activity, Methods Mol Biol 290 (2005), 249-263.
    • (2005) Methods Mol. Biol. , vol.290 , pp. 249-263
    • Stingl, J.1    Emerman, J.T.2    Eaves, C.J.3
  • 48
    • 0029983762 scopus 로고    scopus 로고
    • Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell
    • DOI 10.1006/dbio.1996.0090
    • B.A. Reynolds and S.Weiss, Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell, Dev Biol 175 (1996), 1-13. (Pubitemid 26150042)
    • (1996) Developmental Biology , vol.175 , Issue.1 , pp. 1-13
    • Reynolds, B.A.1    Weiss, S.2
  • 50
    • 34548569038 scopus 로고    scopus 로고
    • Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity
    • M.J. Liao et al., Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity, Cancer Res 67 (2007), 8131-8138.
    • (2007) Cancer Res. , vol.67 , pp. 8131-8138
    • Liao, M.J.1
  • 51
    • 0023887268 scopus 로고
    • Transplantation of human breast epithelia to mammary-gland-free fat-pads of athymic nude mice: Influence of mammotrophic hormones on growth of breast epithelia
    • L.G. Sheffield and C.W. Welsch, Transplantation of human breast epithelia to mammary-gland-free fat-pads of athymic nude mice: influence of mammotrophic hormones on growth of breast epithelia, Int J Cancer 41 (1988), 713-719.
    • (1988) Int. J. Cancer , vol.41 , pp. 713-719
    • Sheffield, L.G.1    Welsch, C.W.2
  • 52
    • 0024097474 scopus 로고
    • Organization and growth of mammary epithelia in the mammary gland fat pad
    • L.G. Sheffield, Organization and growth of mammary epithelia in the mammary gland fat pad, J Dairy Sci 71 (1988), 2855-2874.
    • (1988) J. Dairy Sci. , vol.71 , pp. 2855-2874
    • Sheffield, L.G.1
  • 53
    • 0014202099 scopus 로고
    • Transplantability and life span ofmammary gland during serial transplantation inmice
    • K. Hoshino and W.U. Gardner, Transplantability and life span ofmammary gland during serial transplantation inmice, Nature 213 (1967), 193-194.
    • (1967) Nature , vol.213 , pp. 193-194
    • Hoshino, K.1    Gardner, W.U.2
  • 55
    • 34250632024 scopus 로고    scopus 로고
    • Reconstruction of human mammary tissues in a mouse model
    • D.A. Proia and C. Kuperwasser, Reconstruction of human mammary tissues in a mouse model, Nat Protoc 1 (2006), 206-214.
    • (2006) Nat. Protoc , vol.1 , pp. 206-214
    • Proia, D.A.1    Kuperwasser, C.2
  • 56
    • 66349136558 scopus 로고    scopus 로고
    • Dissecting genetic requirements of human breast tumorigenesis in a tissue transgenic model of human breast cancer in mice
    • U S A
    • M. Wu et al., Dissecting genetic requirements of human breast tumorigenesis in a tissue transgenic model of human breast cancer in mice, Proc Natl Acad Sci U S A 106 (2009), 7022-7027.
    • (2009) Proc. Natl. Acad. Sci. , vol.106 , pp. 7022-7027
    • Wu, M.1
  • 57
    • 57349148680 scopus 로고    scopus 로고
    • Amethod for quantifying normal humanmammary epithelial stem cells with in vivo regenerative ability
    • P. Eirewet al., Amethod for quantifying normal humanmammary epithelial stem cells with in vivo regenerative ability, Nat Med 14 (2008), 1384-1389.
    • (2008) Nat. Med. , vol.14 , pp. 1384-1389
    • Eirew, P.1
  • 58
    • 0031674851 scopus 로고    scopus 로고
    • Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast
    • DOI 10.1111/j.1432-0436.1998.00201.x
    • J. Stingl et al., Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast, Differentiation 63 (1998), 201-213. (Pubitemid 28428734)
    • (1998) Differentiation , vol.63 , Issue.4 , pp. 201-213
    • Stingl, J.1    Eaves, C.J.2    Kuusk, U.3    Emerman, J.T.4
  • 59
    • 0034880458 scopus 로고    scopus 로고
    • Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
    • DOI 10.1023/A:1010615124301
    • J. Stingl et al., Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue, Breast Cancer Res Treat 67 (2001), 93-109. (Pubitemid 32744490)
    • (2001) Breast Cancer Research and Treatment , vol.67 , Issue.2 , pp. 93-109
    • Stingl, J.1    Eaves, C.J.2    Zandieh, I.3    Emerman, J.T.4
  • 60
    • 68349130357 scopus 로고    scopus 로고
    • Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    • E. Lim et al., Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers, Nat Med 15 (2009), 907-913.
    • (2009) Nat. Med. , vol.15 , pp. 907-913
    • Lim, E.1
  • 61
    • 48649096223 scopus 로고    scopus 로고
    • Transcriptome analysis of the normal human mammary cell commitment and differentiation process
    • A. Raouf et al., Transcriptome analysis of the normal human mammary cell commitment and differentiation process, Cell Stem Cell 3 (2008), 109-118.
    • (2008) Cell Stem. Cell. , vol.3 , pp. 109-118
    • Raouf, A.1
  • 62
    • 67349191354 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase as a marker for stem cells
    • J.S. Moreb, Aldehyde dehydrogenase as a marker for stem cells, Curr Stem Cell Res Ther 3 (2008), 237-246.
    • (2008) Curr. Stem. Cell Res. Ther. , vol.3 , pp. 237-246
    • Moreb, J.S.1
  • 65
    • 77956184440 scopus 로고    scopus 로고
    • Expression of the stem cell marker ALDH1 in the normal breast of BRCA1 mutation carriers
    • M.R. Heerma van Voss et al., Expression of the stem cell marker ALDH1 in the normal breast of BRCA1 mutation carriers, Breast Cancer Res Treat 123 (2010), 611-612.
    • (2010) Breast. Cancer Res. Treat. , vol.123 , pp. 611-612
    • Voss Van Heerma, M.R.1
  • 66
    • 33645514001 scopus 로고    scopus 로고
    • A side order of stem cells: The SP phenotype
    • G.A. Challen and M.H. Little, A side order of stem cells: the SP phenotype, Stem Cells 24 (2006), 3-12.
    • (2006) Stem. Cells , vol.24 , pp. 3-12
    • Challen, G.A.1    Little, M.H.2
  • 68
    • 19444378108 scopus 로고    scopus 로고
    • The Mammary gland "side population": A putative stem/progenitor cell marker
    • DOI 10.1007/s10911-005-2539-0
    • M.J. Smalley and R.B. Clarke, The mammary gland "side population": a putative stem/progenitor cell marker? JMammary Gland Biol Neoplasia 10 (2005), 37-47. (Pubitemid 40724021)
    • (2005) Journal of Mammary Gland Biology and Neoplasia , vol.10 , Issue.1 , pp. 37-47
    • Smalley, M.J.1    Clarke, R.B.2
  • 69
    • 2942748109 scopus 로고    scopus 로고
    • Growth and differentiation of progenitor/stem cells derived from the human mammary gland
    • DOI 10.1016/j.yexcr.2004.03.029, PII S0014482704001685
    • H. Clayton, I. Titley and M. Vivanco, Growth and differentiation of progenitor/stem cells derived from the human mammary gland, Exp Cell Res 297 (2004), 444-460. (Pubitemid 38798406)
    • (2004) Experimental Cell Research , vol.297 , Issue.2 , pp. 444-460
    • Clayton, H.1    Titley, I.2    Vivanco, M.3
  • 70
    • 1642486729 scopus 로고    scopus 로고
    • Functional and molecular characterisation of mammary side population cells
    • A.J. Alvi et al., Functional and molecular characterisation of mammary side population cells, Breast Cancer Res 5 (2003), R1-8.
    • (2003) Breast Cancer Res. , vol.5
    • Alvi, A.J.1
  • 71
    • 11144340909 scopus 로고    scopus 로고
    • A putative human breast stem cell population is enriched for steroid receptor-positive cells
    • DOI 10.1016/j.ydbio.2004.07.044, PII S0012160604007171
    • R.B. Clarke et al., A putative human breast stem cell population is enriched for steroid receptor-positive cells, Dev Biol 277 (2005), 443-456. (Pubitemid 40022963)
    • (2005) Developmental Biology , vol.277 , Issue.2 , pp. 443-456
    • Clarke, R.B.1    Spence, K.2    Anderson, E.3    Howell, A.4    Okano, H.5    Potten, C.S.6
  • 72
    • 28544452194 scopus 로고    scopus 로고
    • Isolation and characterization of human mammary stem cells
    • DOI 10.1111/j.1365-2184.2005.00357.x
    • R.B. Clarke, Isolation and characterization of human mammary stem cells, Cell Prolif 38 (2005), 375-386. (Pubitemid 41746370)
    • (2005) Cell Proliferation , vol.38 , Issue.6 , pp. 375-386
    • Clarke, R.B.1
  • 73
    • 79956351015 scopus 로고    scopus 로고
    • Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
    • U S A
    • C.L. Chaffer et al., Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state, Proc Natl Acad Sci U S A 108 (2011), 7950-7955.
    • (2011) Proc. Natl. Acad. Sci. , vol.108 , pp. 7950-7955
    • Chaffer, C.L.1
  • 74
    • 36248949045 scopus 로고    scopus 로고
    • Stem cells and the stem cell niche in the breast: An integrated hormonal and developmental perspective
    • DOI 10.1007/s12015-007-0019-1, PII SCR32147
    • C. Brisken and S. Duss, Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective, Stem Cell Rev 3 (2007), 147-156. (Pubitemid 350129717)
    • (2007) Stem Cell Reviews , vol.3 , Issue.2 , pp. 147-156
    • Brisken, C.1    Duss, S.2
  • 75
    • 0026535130 scopus 로고
    • Changes in the extracellular matrix of the normal human breast during the menstrual cycle
    • J.E. Ferguson et al., Changes in the extracellular matrix of the normal human breast during the menstrual cycle, Cell Tissue Res 268 (1992), 167-177.
    • (1992) Cell Tissue Res. , vol.268 , pp. 167-177
    • Ferguson, J.E.1
  • 76
    • 77953388315 scopus 로고    scopus 로고
    • Progesterone induces adult mammary stem cell expansion
    • P.A. Joshi et al., Progesterone induces adult mammary stem cell expansion, Nature 465 (2010), 803-807.
    • (2010) Nature , vol.465 , pp. 803-807
    • Joshi, P.A.1
  • 78
    • 60949084535 scopus 로고    scopus 로고
    • Cancer stem cells: A model in the making
    • L.L. Marotta and K. Polyak, Cancer stem cells: a model in the making, Curr Opin Genet Dev 19 (2009), 44-50.
    • (2009) Curr. Opin. Genet. Dev. , vol.19 , pp. 44-50
    • Marotta, L.L.1    Polyak, K.2
  • 79
    • 42549099061 scopus 로고    scopus 로고
    • The cancer stem cell hypothesis: In search of definitions, markers, and relevance
    • DOI 10.1038/labinvest.2008.14, PII LABINVEST200814
    • M. Shipitsin and K. Polyak, The cancer stem cell hypothesis: in search of definitions, markers, and relevance, Lab Invest 88 (2008), 459-463. (Pubitemid 351581449)
    • (2008) Laboratory Investigation , vol.88 , Issue.5 , pp. 459-463
    • Shipitsin, M.1    Polyak, K.2
  • 80
    • 34548831213 scopus 로고    scopus 로고
    • The biology of cancer stem cells
    • N.A. Lobo et al., The biology of cancer stem cells, Annu Rev Cell Dev Biol 23 (2007), 675-699.
    • (2007) Annu. Rev. Cell Dev. Biol. , vol.23 , pp. 675-699
    • Lobo, N.A.1
  • 83
    • 33751346643 scopus 로고    scopus 로고
    • +/CD24- breast cancer cells exhibit enhanced invasive properties: An early step necessary for metastasis
    • +/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis, Breast Cancer Res 8 (2006), R59.
    • (2006) Breast Cancer Res. , vol.8
    • Sheridan, C.1
  • 84
    • 77954860302 scopus 로고    scopus 로고
    • Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44 hi/ CD24 lo/- stem cell phenotype in human breast cancer
    • T. Blick et al., Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44 (hi/) CD24 (lo/-) stem cell phenotype in human breast cancer, J Mammary Gland Biol Neoplasia 15 (2010), 235-252.
    • (2010) J. Mammary Gland Biol. Neoplasia , vol.15 , pp. 235-252
    • Blick, T.1
  • 85
    • 80052443909 scopus 로고    scopus 로고
    • +/CD24- phenotype relates to triple-negative state and unfavorable prognosis in breast cancer patients
    • +/CD24- phenotype relates to 'triple-negative' state and unfavorable prognosis in breast cancer patients, Med Oncol, (2010).
    • (2010) Med. Oncol.
    • Giatromanolaki, A.1
  • 86
    • 55749104730 scopus 로고    scopus 로고
    • +/CD24- phenotype is enriched in basal-like breast tumors
    • +/CD24- phenotype is enriched in basal-like breast tumors, Breast Cancer Res 10 (2008), R53.
    • (2008) Breast Cancer Res. , vol.10
    • Honeth, G.1
  • 87
    • 80054879984 scopus 로고    scopus 로고
    • Breast cancer stem cell markers CD44 CD24 and ALDH1: Expression distribution within intrinsic molecular subtype
    • S. Ricardo et al., Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype, J Clin Pathol, (2011).
    • (2011) J. Clin. Pathol.
    • Ricardo, S.1
  • 88
    • 77953160885 scopus 로고    scopus 로고
    • Dynamic regulation of CD24 and the invasive CD44posCD24neg phenotype in breast cancer cell lines
    • M.J. Meyer et al., Dynamic regulation of CD24 and the invasive, CD44posCD24neg phenotype in breast cancer cell lines, Breast Cancer Res 11 (2009), R82.
    • (2009) Breast Cancer Res. , vol.11
    • Meyer, M.J.1
  • 89
    • 77953163539 scopus 로고    scopus 로고
    • CD44posCD49fhiCD133/2hi defines xenograft-initiating cells in estrogen receptor-negative breast cancer
    • M.J. Meyer et al., CD44posCD49fhiCD133/2hi defines xenograft-initiating cells in estrogen receptor-negative breast cancer, Cancer Res 70 (2010), 4624-4633.
    • (2010) Cancer Res. , vol.70 , pp. 4624-4633
    • Meyer, M.J.1
  • 90
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • S.A.Mani et al., The epithelial-mesenchymal transition generates cells with properties of stem cells, Cell 133 (2008), 704-715.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1
  • 91
    • 77956218241 scopus 로고    scopus 로고
    • BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
    • G. Molyneux et al., BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells, Cell Stem Cell 7 (2010), 403-417.
    • (2010) Cell Stem. Cell , vol.7 , pp. 403-417
    • Molyneux, G.1
  • 92
    • 77956215419 scopus 로고    scopus 로고
    • Cancer cell of origin: Spotlight on luminal progenitors
    • C.L. Chaffer and R.A.Weinberg, Cancer cell of origin: spotlight on luminal progenitors, Cell Stem Cell 7 (2010), 271-272.
    • (2010) Cell Stem. Cell , vol.7 , pp. 271-272
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 93
    • 49649084774 scopus 로고    scopus 로고
    • An integrative hypothesis about the origin and development of sporadic and familial breast cancer subtypes
    • L. Melchor and J. Benitez, An integrative hypothesis about the origin and development of sporadic and familial breast cancer subtypes, Carcinogenesis 29 (2008), 1475-1482.
    • (2008) Carcinogenesis , vol.29 , pp. 1475-1482
    • Melchor, L.1    Benitez, J.2
  • 94
    • 77956032288 scopus 로고    scopus 로고
    • Estrogen receptor positive breast cancers in BRCA1 mutation carriers: Clinical risk factors and pathologic features
    • N. Tung et al., Estrogen receptor positive breast cancers in BRCA1 mutation carriers: clinical risk factors and pathologic features, Breast Cancer Res 12 (2010), R12.
    • (2010) Breast Cancer Res. , vol.12
    • Tung, N.1
  • 95
    • 77955773149 scopus 로고    scopus 로고
    • Prognostic impact of ALDH1 in breast cancer: A story of stem cells and tumor microenvironment
    • E. Resetkova et al., Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment, Breast Cancer Res Treat 123 (2010), 97-108.
    • (2010) Breast. Cancer Res. Treat. , vol.123 , pp. 97-108
    • Resetkova, E.1
  • 96
    • 69249208657 scopus 로고    scopus 로고
    • Getting to the root of BRCA1-deficient breast cancer
    • C. Ginestier, S. Liu and M.S. Wicha, Getting to the root of BRCA1-deficient breast cancer, Cell Stem Cell 5 (2009), 229-230.
    • (2009) Cell Stem. Cell , vol.5 , pp. 229-230
    • Ginestier, C.1    Liu, S.2    Wicha, M.S.3
  • 97
    • 77955463831 scopus 로고    scopus 로고
    • Exon-level microarray analyses identify alternative splicing programs in breast cancer
    • A. Lapuk et al., Exon-level microarray analyses identify alternative splicing programs in breast cancer, Mol Cancer Res 8 (2010), 961-974.
    • (2010) Mol. Cancer Res. , vol.8 , pp. 961-974
    • Lapuk, A.1
  • 99
    • 77950863930 scopus 로고    scopus 로고
    • Worse prognosis of metaplastic breast cancer patients than other patients with triple-negative breast cancer
    • S.Y. Jung et al.,Worse prognosis of metaplastic breast cancer patients than other patients with triple-negative breast cancer, Breast Cancer Res Treat 120 (2010), 627-637.
    • (2010) Breast. Cancer Res. Treat. , vol.120 , pp. 627-637
    • Jung, S.Y.1
  • 100
    • 66249109653 scopus 로고    scopus 로고
    • Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics
    • B.T. Hennessy et al., Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics, Cancer Res 69 (2009), 4116-4124.
    • (2009) Cancer Res. , vol.69 , pp. 4116-4124
    • Hennessy, B.T.1
  • 101
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • K. Takahashi et al., Induction of pluripotent stem cells from adult human fibroblasts by defined factors, Cell 131 (2007), 861-872. (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 102
    • 77953466536 scopus 로고    scopus 로고
    • Nuclear reprogramming to a pluripotent state by three approaches
    • S. Yamanaka and H.M. Blau, Nuclear reprogramming to a pluripotent state by three approaches, Nature 465 (2010), 704-712.
    • (2010) Nature , vol.465 , pp. 704-712
    • Yamanaka, S.1    Blau, H.M.2
  • 104
    • 77954351997 scopus 로고    scopus 로고
    • Synthetic lethality through combined Notchepidermal growth factor receptor pathway inhibition in basallike breast cancer
    • Y. Dong et al., Synthetic lethality through combined Notchepidermal growth factor receptor pathway inhibition in basallike breast cancer, Cancer Res 70 (2010), 5465-5474.
    • (2010) Cancer Res. , vol.70 , pp. 5465-5474
    • Dong, Y.1
  • 105
    • 18944375734 scopus 로고    scopus 로고
    • Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells
    • G. Dontu et al., Role of Notch signaling in cell-fate determination of human mammary stem/progenitor cells, Breast Cancer Res 6 (2004), R605-615.
    • (2004) Breast Cancer Res. , vol.6
    • Dontu, G.1
  • 106
    • 63649147784 scopus 로고    scopus 로고
    • Dysregulation of hedgehog wnt and notch signalling pathways in breast cancer
    • S.J. Zardawi et al., Dysregulation of Hedgehog, Wnt and Notch signalling pathways in breast cancer, Histol Histopathol 24 (2009), 385-398.
    • (2009) Histol. Histopathol. , vol.24 , pp. 385-398
    • Zardawi, S.J.1
  • 107
    • 77953183234 scopus 로고    scopus 로고
    • Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome
    • A.I. Khramtsov et al., Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome, Am J Pathol 176 (2010), 2911-2920.
    • (2010) Am. J. Pathol. , vol.176 , pp. 2911-2920
    • Khramtsov, A.I.1
  • 108
    • 78650248243 scopus 로고    scopus 로고
    • Inhibition of notch signaling reduces the stem-like population of breast cancer cells and prevents mammosphere formation
    • P. Grudzien et al., Inhibition of Notch Signaling Reduces the Stem-like Population of Breast Cancer Cells and Prevents Mammosphere Formation, Anticancer Res 30 (2010), 3853-3867.
    • (2010) Anticancer Res. , vol.30 , pp. 3853-3867
    • Grudzien, P.1
  • 109
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • K. Polyak and R.A.Weinberg, Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits, Nat Rev Cancer 9 (2009), 265-273.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 110
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • P.B. Gupta et al., Identification of selective inhibitors of cancer stem cells by high-throughput screening, Cell 138 (2009), 645-659.
    • (2009) Cell , vol.138 , pp. 645-659
    • Gupta, P.B.1
  • 111
    • 4444291401 scopus 로고    scopus 로고
    • DNA methylation as a therapeutic target in hematologic disorders: Recent results in older patients with myelodysplasia and acute myeloid leukemia
    • DOI 10.1532/IJH97.04094
    • B. Ruter, P.W.Wijermans and M. Lubbert, DNA methylation as a therapeutic target in hematologic disorders: recent results in older patients withmyelodysplasia and acute myeloid leukemia, Int J Hematol 80 (2004), 128-135. (Pubitemid 39201565)
    • (2004) International Journal of Hematology , vol.80 , Issue.2 , pp. 128-135
    • Ruter, B.1    Wijermans, P.W.2    Lubbert, M.3
  • 112
    • 0029002319 scopus 로고
    • Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression
    • A.T. Ferguson et al., Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression, Cancer Res 55 (1995), 2279-2283.
    • (1995) Cancer Res. , vol.55 , pp. 2279-2283
    • Ferguson, A.T.1
  • 113
    • 0035477320 scopus 로고    scopus 로고
    • Synergistic activation of functional estrogen receptor (ER)-α by DNA methyltransferase and histone deacetylase inhibition in human ER-α-negative breast cancer cells
    • X. Yang et al., Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells, Cancer Res 61 (2001), 7025-7029. (Pubitemid 32946489)
    • (2001) Cancer Research , vol.61 , Issue.19 , pp. 7025-7029
    • Yang, X.1    Phillips, D.L.2    Ferguson, A.T.3    Nelson, W.G.4    Herman, J.G.5    Davidson, N.E.6
  • 114
    • 77149166638 scopus 로고    scopus 로고
    • The epigenetic landscape of mammary gland development and functional differentiation
    • M. Rijnkels et al., The epigenetic landscape of mammary gland development and functional differentiation, JMammary Gland Biol Neoplasia 15 (2010), 85-100.
    • (2010) J. Mammary Gland. Biol. Neoplasia , vol.15 , pp. 85-100
    • Rijnkels, M.1


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