메뉴 건너뛰기




Volumn 70, Issue 11, 2010, Pages 4624-4633

CD44posCD49fhiCD133/2hi defines xenograft-initiating cells in estrogen receptor-negative breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA6 INTEGRIN; BMI1 PROTEIN; CD133 ANTIGEN; CD44V ANTIGEN; ESTROGEN RECEPTOR; INTERLEUKIN 2 RECEPTOR GAMMA; TRANSCRIPTION FACTOR NANOG; CD44 PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR ALPHA; GLYCOPROTEIN; HERMES ANTIGEN; LEUKOCYTE ANTIGEN; PEPTIDE;

EID: 77953163539     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-3619     Document Type: Article
Times cited : (153)

References (48)
  • 2
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3:730-737
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 4
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008;8:755-768
    • (2008) Nat Rev Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 5
    • 30144432901 scopus 로고    scopus 로고
    • Purification and unique properties of mammary epithelial stem cells
    • Stingl J, Eirew P, Ricketson I, et al. Purification and unique properties of mammary epithelial stem cells. Nature 2006;439:993-997
    • (2006) Nature , vol.439 , pp. 993-997
    • Stingl, J.1    Eirew, P.2    Ricketson, I.3
  • 6
    • 68349130357 scopus 로고    scopus 로고
    • Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
    • Lim E, Vaillant F, Wu D, et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med 2009;15:907-913
    • (2009) Nat Med , vol.15 , pp. 907-913
    • Lim, E.1    Vaillant, F.2    Wu, D.3
  • 7
    • 0028813315 scopus 로고
    • High expression level of α6 integrin in human breast carcinoma is correlated with reduced survival
    • Friedrichs K, Ruiz P, Franke F, Gille I, Terpe HJ, Imhof BA. High expression level of α6 integrin in human breast carcinoma is correlated with reduced survival. Cancer Res 1995;55:901-906
    • (1995) Cancer Res , vol.55 , pp. 901-906
    • Friedrichs, K.1    Ruiz, P.2    Franke, F.3    Gille, I.4    Terpe, H.J.5    Imhof, B.A.6
  • 9
    • 59049087696 scopus 로고    scopus 로고
    • Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation
    • Zhu L, Gibson P, Currle DS, et al. Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation. Nature 2009;457:603-607
    • (2009) Nature , vol.457 , pp. 603-607
    • Zhu, L.1    Gibson, P.2    Currle, D.S.3
  • 11
  • 12
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet 1998;351:1451-1467
    • (1998) Lancet , vol.351 , pp. 1451-1467
  • 13
    • 33845914783 scopus 로고    scopus 로고
    • 2-Year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: A randomised controlled trial
    • Smith I, Procter M, Gelber RD, et al. 2-Year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial. Lancet 2007;369:29-36.
    • (2007) Lancet , vol.369 , pp. 29-36
    • Smith, I.1    Procter, M.2    Gelber, R.D.3
  • 14
    • 0033533384 scopus 로고    scopus 로고
    • A sensitive new method for rapid detection of abnormal methylation patterns in global DNA and within CpG islands
    • Pogribny I, Yi P, James SJ. A sensitive new method for rapid detection of abnormal methylation patterns in global DNA and within CpG islands. Biochem Biophys Res Commun 1999;262:624-628
    • (1999) Biochem Biophys Res Commun , vol.262 , pp. 624-628
    • Pogribny, I.1    Yi, P.2    James, S.J.3
  • 15
    • 72849142382 scopus 로고    scopus 로고
    • Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures
    • King FW, Ritner C, Liszewski W, et al. Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures. Stem Cells Dev 2009;18:1441-1450
    • (2009) Stem Cells Dev , vol.18 , pp. 1441-1450
    • King, F.W.1    Ritner, C.2    Liszewski, W.3
  • 17
    • 30144433093 scopus 로고    scopus 로고
    • Generation of a functional mammary gland from a single stem cell
    • Shackleton M, Vaillant F, Simpson KJ, et al. Generation of a functional mammary gland from a single stem cell. Nature 2006;439:84-88
    • (2006) Nature , vol.439 , pp. 84-88
    • Shackleton, M.1    Vaillant, F.2    Simpson, K.J.3
  • 18
    • 31044431832 scopus 로고    scopus 로고
    • Characterization and isolation of stem cell-enriched human hair follicle bulge cells
    • Ohyama M, Terunuma A, Tock CL, et al. Characterization and isolation of stem cell-enriched human hair follicle bulge cells. J Clin Invest 2006;116:249-260
    • (2006) J Clin Invest , vol.116 , pp. 249-260
    • Ohyama, M.1    Terunuma, A.2    Tock, C.L.3
  • 19
    • 34447295350 scopus 로고    scopus 로고
    • Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
    • Adewumi O, Aflatoonian B, Ahrlund-Richter L, et al. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol 2007;25:803-816
    • (2007) Nat Biotechnol , vol.25 , pp. 803-816
    • Adewumi, O.1    Aflatoonian, B.2    Ahrlund-Richter, L.3
  • 21
    • 46149089421 scopus 로고    scopus 로고
    • Growth-inhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression
    • Godar S, Ince TA, Bell GW, et al. Growth-inhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression. Cell 2008;134:62-73.
    • (2008) Cell , vol.134 , pp. 62-73
    • Godar, S.1    Ince, T.A.2    Bell, G.W.3
  • 22
    • 47749116454 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells
    • Bourguignon LY, Peyrollier K, Xia W, Gilad E. Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells. J Biol Chem 2008;283:17635-17651
    • (2008) J Biol Chem , vol.283 , pp. 17635-17651
    • Bourguignon, L.Y.1    Peyrollier, K.2    Xia, W.3    Gilad, E.4
  • 23
    • 58149269566 scopus 로고    scopus 로고
    • CD44 is of functional importance for colorectal cancer stem cells
    • Du L, Wang H, He L, et al. CD44 is of functional importance for colorectal cancer stem cells. Clin Cancer Res 2008;14:6751-6760
    • (2008) Clin Cancer Res , vol.14 , pp. 6751-6760
    • Du, L.1    Wang, H.2    He, L.3
  • 24
    • 34548260422 scopus 로고    scopus 로고
    • CD44 regulates cell migration in human colon cancer cells via Lyn kinase and AKT phosphorylation
    • Subramaniam V, Vincent IR, Gardner H, Chan E, Dhamko H, Jothy S. CD44 regulates cell migration in human colon cancer cells via Lyn kinase and AKT phosphorylation. Exp Mol Pathol 2007;83:207-215
    • (2007) Exp Mol Pathol , vol.83 , pp. 207-215
    • Subramaniam, V.1    Vincent, I.R.2    Gardner, H.3    Chan, E.4    Dhamko, H.5    Jothy, S.6
  • 25
    • 36049048637 scopus 로고    scopus 로고
    • Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy
    • Subramaniam V, Vincent IR, Gilakjan M, Jothy S. Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy. Exp Mol Pathol 2007;83:332-340
    • (2007) Exp Mol Pathol , vol.83 , pp. 332-340
    • Subramaniam, V.1    Vincent, I.R.2    Gilakjan, M.3    Jothy, S.4
  • 26
    • 33847419142 scopus 로고    scopus 로고
    • Molecular definition of breast tumor heterogeneity
    • Shipitsin M, Campbell LL, Argani P, et al. Molecular definition of breast tumor heterogeneity. Cancer Cell 2007;11:259-273
    • (2007) Cancer Cell , vol.11 , pp. 259-273
    • Shipitsin, M.1    Campbell, L.L.2    Argani, P.3
  • 27
    • 70350497349 scopus 로고    scopus 로고
    • Autocrine TGF-β signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors
    • Ikushima H, Todo T, Ino Y, Takahashi M, Miyazawa K, Miyazono K. Autocrine TGF-β signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors. Cell Stem Cell 2009;5:504-514
    • (2009) Cell Stem Cell , vol.5 , pp. 504-514
    • Ikushima, H.1    Todo, T.2    Ino, Y.3    Takahashi, M.4    Miyazawa, K.5    Miyazono, K.6
  • 28
    • 70350536767 scopus 로고    scopus 로고
    • A small-molecule inhibitor of Tgf-β signaling replaces sox2 in reprogramming by inducing nanog
    • Ichida JK, Blanchard J, Lam K, et al. A small-molecule inhibitor of Tgf-β signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell 2009;5:491-503.
    • (2009) Cell Stem Cell , vol.5 , pp. 491-503
    • Ichida, J.K.1    Blanchard, J.2    Lam, K.3
  • 29
    • 57449090247 scopus 로고    scopus 로고
    • Control of early fate decisions in human ES cells by distinct states of TGFβ pathway activity
    • Greber B, Lehrach H, Adjaye J. Control of early fate decisions in human ES cells by distinct states of TGFβ pathway activity. Stem Cells Dev 2008;17:1065-1077
    • (2008) Stem Cells Dev , vol.17 , pp. 1065-1077
    • Greber, B.1    Lehrach, H.2    Adjaye, J.3
  • 30
    • 0346100567 scopus 로고    scopus 로고
    • Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
    • Cozzio A, Passegue E, Ayton PM, Karsunky H, Cleary ML, Weissman IL. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev 2003; 17:3029-3035
    • (2003) Genes Dev , vol.17 , pp. 3029-3035
    • Cozzio, A.1    Passegue, E.2    Ayton, P.M.3    Karsunky, H.4    Cleary, M.L.5    Weissman, I.L.6
  • 31
    • 70349438989 scopus 로고    scopus 로고
    • A luminal epithelial stem cell that is a cell of origin for prostate cancer
    • Wang X, Kruithof-de Julio M, Economides KD, et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 2009;461:495-500.
    • (2009) Nature , vol.461 , pp. 495-500
    • Wang, X.1    Kruithof-de Julio, M.2    Economides, K.D.3
  • 32
    • 0028318783 scopus 로고
    • Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells
    • Ottaviano YL, Issa JP, Parl FF, Smith HS, Baylin SB, Davidson NE. Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells. Cancer Res 1994;54:2552-2555 (Pubitemid 24173735)
    • (1994) Cancer Research , vol.54 , Issue.10 , pp. 2552-2555
    • Ottaviano, Y.L.1    Issa, J.-P.2    Parl, F.F.3    Smith, H.S.4    Baylin, S.B.5    Davidson, N.E.6
  • 33
    • 33748274499 scopus 로고    scopus 로고
    • Human embryonic stem cells have a unique epigenetic signature
    • Bibikova M, Chudin E, Wu B, et al. Human embryonic stem cells have a unique epigenetic signature. Genome Res 2006;16:1075-1083
    • (2006) Genome Res , vol.16 , pp. 1075-1083
    • Bibikova, M.1    Chudin, E.2    Wu, B.3
  • 34
    • 49649125042 scopus 로고    scopus 로고
    • Genome-scale DNA methylation maps of pluripotent and differentiated cells
    • Meissner A, Mikkelsen TS, Gu H, et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 2008;454:766-770
    • (2008) Nature , vol.454 , pp. 766-770
    • Meissner, A.1    Mikkelsen, T.S.2    Gu, H.3
  • 35
    • 52949122883 scopus 로고    scopus 로고
    • Cell type-specific DNA methylation patterns in the human breast
    • Bloushtain-Qimron N, Yao J, Snyder EL, et al. Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A 2008;105:14076-14081
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 14076-14081
    • Bloushtain-Qimron, N.1    Yao, J.2    Snyder, E.L.3
  • 36
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006;6:107-116
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 37
    • 22344449361 scopus 로고    scopus 로고
    • Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
    • Molofsky AV, He S, Bydon M, Morrison SJ, Pardal R. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev 2005;19:1432-1437
    • (2005) Genes Dev , vol.19 , pp. 1432-1437
    • Molofsky, A.V.1    He, S.2    Bydon, M.3    Morrison, S.J.4    Pardal, R.5
  • 38
    • 56449126945 scopus 로고    scopus 로고
    • Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
    • Godlewski J, Nowicki MO, Bronisz A, et al. Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 2008;68:9125-9130
    • (2008) Cancer Res , vol.68 , pp. 9125-9130
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3
  • 39
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF, et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005;122:947-956
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 40
    • 59849125142 scopus 로고    scopus 로고
    • SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity
    • Gangemi RM, Griffero F, Marubbi D, et al. SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity. Stem Cells 2009;27:40-48
    • (2009) Stem Cells , vol.27 , pp. 40-48
    • Gangemi, R.M.1    Griffero, F.2    Marubbi, D.3
  • 41
    • 67651003097 scopus 로고    scopus 로고
    • Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells: Involvement of Nanog suppression
    • You JS, Kang JK, Seo DW, et al. Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells: involvement of Nanog suppression. Cancer Res 2009;69:5716-5725
    • (2009) Cancer Res , vol.69 , pp. 5716-5725
    • You, J.S.1    Kang, J.K.2    Seo, D.W.3
  • 43
    • 33645473811 scopus 로고    scopus 로고
    • In search of a stem cell hierarchy in the human breast and its relevance to breast cancer evolution
    • Villadsen R. In search of a stem cell hierarchy in the human breast and its relevance to breast cancer evolution. APMIS 2005;113:903-921
    • (2005) APMIS , vol.113 , pp. 903-921
    • Villadsen, R.1
  • 45
    • 67849124654 scopus 로고    scopus 로고
    • DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency
    • Hoey T, Yen WC, Axelrod F, et al. DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Cell Stem Cell 2009;5:168-177
    • (2009) Cell Stem Cell , vol.5 , pp. 168-177
    • Hoey, T.1    Yen, W.C.2    Axelrod, F.3
  • 46
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • Gupta PB, Onder TT, Jiang G, et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 2009;138:645-659
    • (2009) Cell , vol.138 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3
  • 47
    • 69549114870 scopus 로고    scopus 로고
    • Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
    • Chan KS, Espinosa I, Chao M, et al. Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A 2009;106:14016-14021
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14016-14021
    • Chan, K.S.1    Espinosa, I.2    Chao, M.3
  • 48
    • 55949092708 scopus 로고    scopus 로고
    • High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs
    • Rottenberg S, Jaspers JE, Kersbergen A, et al. High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs. Proc Natl Acad Sci U S A 2008;105:17079-17084
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 17079-17084
    • Rottenberg, S.1    Jaspers, J.E.2    Kersbergen, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.