Suppressive effect of enzymatically modified isoquercitrin on phenobarbital-induced liver tumor promotion in rats

Archives of Toxicology

Volumn 85, Issue 11, 2011, Pages 1475-1484

  Morita, Reiko ^a   Shimamoto, Keisuke ^a,b   Ishii, Yuji ^c   Kuwata, Kazunori ^a   Ogawa, Bun Ichiro ^a   Imaoka, Masako ^a   Hayashi, Shim Mo ^d   Suzuki, Kazuhiko ^a   Shibutani, Makoto ^a   Mitsumori, Kunitoshi ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d SAN EI GEN F F I INC   (Japan)

Author keywords

CYP2B inducer; Enzymatically modified isoquercitrin; Liver tumor; Phenobarbital; Rat; Reactive oxygen species

Indexed keywords

CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 2B2; DIETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE; ISOQUERCITRIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 2; PHENOBARBITAL; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG EFFECT; DRUG INDUCED CANCER; FEMALE; GENE EXPRESSION; LIVER MICROSOME; LIVER TUMOR; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; TUMOR PROMOTION;

ANIMALS; ANTICARCINOGENIC AGENTS; ARYL HYDROCARBON HYDROXYLASES; ATP-BINDING CASSETTE TRANSPORTERS; DIETHYLNITROSAMINE; DRINKING WATER; GLUTATHIONE TRANSFERASE; HEPATECTOMY; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; OXIDATIVE STRESS; PHENOBARBITAL; QUERCETIN; RATS; RATS, INBRED F344; REACTIVE OXYGEN SPECIES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; STEROID HYDROXYLASES;

RATTUS;

EID: 80755135480     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0696-z     Document Type: Article

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