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Volumn 45, Issue 2, 2007, Pages 171-201

The FEMA GRAS assessment of aromatic substituted secondary alcohols, ketones, and related esters used as flavor ingredients

Author keywords

Aromatic ketones; FEMA GRAS; Flavoring ingredients

Indexed keywords

1 (1 METHOXYPHENYL) 1 PENTEN 3 ONE; 1 PHENYL 1 PROPANOL; 1 PHENYL 1,2 PROPANEDIONE; 1 PHENYLETHANOL; 4 (4 METHOXYPHENYL) 2 BUTANONE; 4 METHYL 1 PHENYL 2 PENTANOL; ACETOPHENONE; ALCOHOL DERIVATIVE; ALPHA METHYLPHENETHYLBUTYRATE; BENZOIN; BENZOPHENONE; CARCINOGEN; ESTER; FLAVORING AGENT; KETONE; METHYL BETA NAPHTHYL KETONE;

EID: 33845214883     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.07.029     Document Type: Review
Times cited : (36)

References (128)
  • 2
    • 0024376682 scopus 로고
    • The induction of DNA strand breaks and unscheduled DNA synthesis in F344 rat hepatocytes following in vivo administration of caprolactam or benzoin
    • Bermudez E., Smith-Oliver T., and Delehanty L.L. The induction of DNA strand breaks and unscheduled DNA synthesis in F344 rat hepatocytes following in vivo administration of caprolactam or benzoin. Mutat. Res. 224 (1989) 361-364
    • (1989) Mutat. Res. , vol.224 , pp. 361-364
    • Bermudez, E.1    Smith-Oliver, T.2    Delehanty, L.L.3
  • 3
    • 0344019005 scopus 로고    scopus 로고
    • C-cell hyperplasia, C-cell adenoma, and C-cell carcinoma thyroid, rat
    • Jones T.C., Capen C.C., and Mohr U. (Eds), Springer-Verlag, Berlin
    • Boorman G.A., DeLellis R.A., and Elwell M.R. C-cell hyperplasia, C-cell adenoma, and C-cell carcinoma thyroid, rat. In: Jones T.C., Capen C.C., and Mohr U. (Eds). Endocrine System: Monograph of Pathology of Laboratory Animals (1996), Springer-Verlag, Berlin 262-274
    • (1996) Endocrine System: Monograph of Pathology of Laboratory Animals , pp. 262-274
    • Boorman, G.A.1    DeLellis, R.A.2    Elwell, M.R.3
  • 4
    • 33645928798 scopus 로고
    • Anticonvulsant properties of certain secondary and tertiary alcohols
    • Brown B., Schaffarzick R.W., and Dreisbach R.H. Anticonvulsant properties of certain secondary and tertiary alcohols. J. Pharmacol. Exp. Ther. 115 (1955) 230-239
    • (1955) J. Pharmacol. Exp. Ther. , vol.115 , pp. 230-239
    • Brown, B.1    Schaffarzick, R.W.2    Dreisbach, R.H.3
  • 5
    • 33845198850 scopus 로고
    • Choleretic action of 1-phenylpropanol
    • Brugel H., Docker O., and Mertz D.P. Choleretic action of 1-phenylpropanol. Dt. med. Wschr. 81 (1956) 1679-1681
    • (1956) Dt. med. Wschr. , vol.81 , pp. 1679-1681
    • Brugel, H.1    Docker, O.2    Mertz, D.P.3
  • 6
    • 0023010822 scopus 로고
    • Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations
    • Brusick D. Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations. Environ. Mutagen. 8 (1986) 879-886
    • (1986) Environ. Mutagen. , vol.8 , pp. 879-886
    • Brusick, D.1
  • 10
    • 33845201304 scopus 로고    scopus 로고
    • Calandra, J.C., 1971. Acute toxicity study in rats and rabbits. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 11
    • 33845206525 scopus 로고
    • Dehydrogenation of methylphenylcarbinol by soluble preparations of rat liver
    • Callaghan P., Borge P.A., Elsden J., and Hopkins R.P. Dehydrogenation of methylphenylcarbinol by soluble preparations of rat liver. Biochem. Soc. Trans. 1 (1973) 421-423
    • (1973) Biochem. Soc. Trans. , vol.1 , pp. 421-423
    • Callaghan, P.1    Borge, P.A.2    Elsden, J.3    Hopkins, R.P.4
  • 12
    • 0017136107 scopus 로고
    • Toxicological studies of photosensitizer agents and photodegradable polyolefins
    • Caprino L., Togna G., and Mazzei M. Toxicological studies of photosensitizer agents and photodegradable polyolefins. Eur. J. Toxicol. Environ. Hyg. 9 2 (1976) 99-103
    • (1976) Eur. J. Toxicol. Environ. Hyg. , vol.9 , Issue.2 , pp. 99-103
    • Caprino, L.1    Togna, G.2    Mazzei, M.3
  • 14
    • 0019520011 scopus 로고
    • The effects of cofactor and species differences on the in vitro metabolism of propiophenone and phenylacetone
    • Coutts R.T., Prelusky D.B., and Jones G.R. The effects of cofactor and species differences on the in vitro metabolism of propiophenone and phenylacetone. Can. J. Physiol. Pharmacol. 59 (1981) 195-201
    • (1981) Can. J. Physiol. Pharmacol. , vol.59 , pp. 195-201
    • Coutts, R.T.1    Prelusky, D.B.2    Jones, G.R.3
  • 15
    • 0014429121 scopus 로고
    • The partial purification and properties of a reduced triphosphopyridine nucleotide-dependent reductase from rabbit kidney cortex
    • Culp H.W., and McMahon R.E. The partial purification and properties of a reduced triphosphopyridine nucleotide-dependent reductase from rabbit kidney cortex. J. Biol. Chem. 243 (1968) 848-852
    • (1968) J. Biol. Chem. , vol.243 , pp. 848-852
    • Culp, H.W.1    McMahon, R.E.2
  • 16
    • 33845223505 scopus 로고    scopus 로고
    • Damment, S.J.P., 1992. Acute oral toxicity (LD50) in the rat. Test article: E9120 ECM5TS S49 Benzyl alcohol. Unpublished report to the Environmental Protection Agency, Washington, DC.
  • 17
    • 0000159334 scopus 로고
    • Tests for chromosome aberrations and aneuploidy in the Chinese hamster fibroblast cell line CH1-L
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Danford N. Tests for chromosome aberrations and aneuploidy in the Chinese hamster fibroblast cell line CH1-L. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 397-411
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 397-411
    • Danford, N.1
  • 18
    • 33845191979 scopus 로고    scopus 로고
    • Denine, E.P., Palanker, A.L., 1973. Acute oral and dermal toxicity studies. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 19
    • 33845211942 scopus 로고    scopus 로고
    • Toxicokinetics of benzophenone (BPH) in male and female rats and mice
    • Dix K.J., Grizzle T.B., Handy R.W., Brine D.R., and Collins B.J. Toxicokinetics of benzophenone (BPH) in male and female rats and mice. Toxicologist 36 1 part 2 (1997) 141
    • (1997) Toxicologist , vol.36 , Issue.1 PART 2 , pp. 141
    • Dix, K.J.1    Grizzle, T.B.2    Handy, R.W.3    Brine, D.R.4    Collins, B.J.5
  • 20
    • 0026700463 scopus 로고
    • A contribution to the study of the structure-mutagenicity relationship for alpha-dicarbonyl compounds using the Ames test
    • Dorado L., Montoya M.R., and Rodriguez-Mellado J.M. A contribution to the study of the structure-mutagenicity relationship for alpha-dicarbonyl compounds using the Ames test. Mutat. Res. 269 (1992) 301-306
    • (1992) Mutat. Res. , vol.269 , pp. 301-306
    • Dorado, L.1    Montoya, M.R.2    Rodriguez-Mellado, J.M.3
  • 22
    • 77049273959 scopus 로고
    • Studies in detoxication. 69. The metabolism of alkylbenzenes: n-propylbenzene and n-butylbenzene with further observations on ethylbenzene
    • El Masry A.M., Smith J.N., and Williams R.T. Studies in detoxication. 69. The metabolism of alkylbenzenes: n-propylbenzene and n-butylbenzene with further observations on ethylbenzene. Biochem. J. 64 (1956) 50-57
    • (1956) Biochem. J. , vol.64 , pp. 50-57
    • El Masry, A.M.1    Smith, J.N.2    Williams, R.T.3
  • 23
    • 0028597055 scopus 로고
    • The utility of multiple-section sampling in the histopathological evaluation of the kidney for carcinogenicity studies
    • Eustis S.L., Hailey J.R., Booman G.A., and Haseman J.K. The utility of multiple-section sampling in the histopathological evaluation of the kidney for carcinogenicity studies. Toxicol. Pathol. 22 5 (1994) 457-472
    • (1994) Toxicol. Pathol. , vol.22 , Issue.5 , pp. 457-472
    • Eustis, S.L.1    Hailey, J.R.2    Booman, G.A.3    Haseman, J.K.4
  • 25
    • 0018822306 scopus 로고
    • Screening of tobacco smoke constituents for mutagenicity testing using Ames test
    • Florin I., Rutberg L., Curvall M., and Enzell C.R. Screening of tobacco smoke constituents for mutagenicity testing using Ames test. Toxicology 18 (1980) 219-232
    • (1980) Toxicology , vol.18 , pp. 219-232
    • Florin, I.1    Rutberg, L.2    Curvall, M.3    Enzell, C.R.4
  • 26
    • 33845212435 scopus 로고    scopus 로고
    • Fogleman, R.W., Margolin, S., 1970. Acute oral toxicity studies in rats. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 27
    • 33845217656 scopus 로고    scopus 로고
    • Food and Drug Administration (FDA), 1993. Priority-based assessment of food additives (PAFA) database. Center for food safety and applied nutrition, p. 58.
  • 28
    • 0020528517 scopus 로고
    • Short-term toxicity of 4-methyl-1-phenylpentan-2-o1 in rats
    • Ford G.P., Gopal T., and Gaunt I.F. Short-term toxicity of 4-methyl-1-phenylpentan-2-o1 in rats. Food Chem. Toxicol. 21 (1983) 441-447
    • (1983) Food Chem. Toxicol. , vol.21 , pp. 441-447
    • Ford, G.P.1    Gopal, T.2    Gaunt, I.F.3
  • 29
    • 0001136781 scopus 로고
    • Mutagenicity test of food additives with Salmonella typhimurium TA97 and TA102. II
    • Fujita H., and Sasaki M. Mutagenicity test of food additives with Salmonella typhimurium TA97 and TA102. II. Ann. Rep. Tokyo Metro. Res. Lab. Pub. Health 38 (1987) 423-430
    • (1987) Ann. Rep. Tokyo Metro. Res. Lab. Pub. Health , vol.38 , pp. 423-430
    • Fujita, H.1    Sasaki, M.2
  • 32
    • 2642655272 scopus 로고    scopus 로고
    • Synthesis and enzymatic hydrolysis of esters constituting simple models of soft drugs
    • Graffner-Nordberg M., Sjodin K., Tunek A., and Hallberg A. Synthesis and enzymatic hydrolysis of esters constituting simple models of soft drugs. Chem. Pharm. Bull. 46 (1998) 591-601
    • (1998) Chem. Pharm. Bull. , vol.46 , pp. 591-601
    • Graffner-Nordberg, M.1    Sjodin, K.2    Tunek, A.3    Hallberg, A.4
  • 33
    • 0024401672 scopus 로고
    • Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro III: results with 27 chemicals
    • Gulati D.K., Witt K., Anderson B., Zeiger E., and Shelby M.D. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro III: results with 27 chemicals. Environ. Mol. Mutagen. 13 (1989) 133-193
    • (1989) Environ. Mol. Mutagen. , vol.13 , pp. 133-193
    • Gulati, D.K.1    Witt, K.2    Anderson, B.3    Zeiger, E.4    Shelby, M.D.5
  • 35
    • 0036946031 scopus 로고    scopus 로고
    • Partial outlet obstruction of the rat bladder induces a stimulatory response on proliferation of the bladder smooth muscle cells
    • Hanai T., Ma F.H., Matsumoto S., Park Y.C., and Kurita T. Partial outlet obstruction of the rat bladder induces a stimulatory response on proliferation of the bladder smooth muscle cells. Int. Urol. Nephrol. 34 (2002) 37-42
    • (2002) Int. Urol. Nephrol. , vol.34 , pp. 37-42
    • Hanai, T.1    Ma, F.H.2    Matsumoto, S.3    Park, Y.C.4    Kurita, T.5
  • 36
    • 0031935131 scopus 로고    scopus 로고
    • Mechanisms of chemically induced renal carcinogenesis in the laboratory rodent
    • Hard G.C. Mechanisms of chemically induced renal carcinogenesis in the laboratory rodent. Toxicol. Pathol. 26 (1998) 104-112
    • (1998) Toxicol. Pathol. , vol.26 , pp. 104-112
    • Hard, G.C.1
  • 37
    • 1842563805 scopus 로고    scopus 로고
    • A contemporary overview of chronic progressive nephropahy in the laboratory rat, and its significance for human risk assessment
    • Hard G.C., and Khan K.N. A contemporary overview of chronic progressive nephropahy in the laboratory rat, and its significance for human risk assessment. Toxicol. Pathol. 32 (2004) 171-180
    • (2004) Toxicol. Pathol. , vol.32 , pp. 171-180
    • Hard, G.C.1    Khan, K.N.2
  • 38
    • 33644810893 scopus 로고    scopus 로고
    • Recommendations for the interpretation of renal tubule proliferative lesions occurring in rat kidneys with advanced chronic progressive nephropathy (CPN)
    • Hard G.C., and Seely J.C. Recommendations for the interpretation of renal tubule proliferative lesions occurring in rat kidneys with advanced chronic progressive nephropathy (CPN). Toxicol. Pathol. 33 (2005) 641-649
    • (2005) Toxicol. Pathol. , vol.33 , pp. 641-649
    • Hard, G.C.1    Seely, J.C.2
  • 39
    • 0031955224 scopus 로고    scopus 로고
    • Spontaneous neoplasm incidences in Fischer 344 rats and B6C3F(1) mice in two-year carcinogenicity studies: A National Toxicology Program update
    • Haseman J.K., Hailey J.R., and Morris R.W. Spontaneous neoplasm incidences in Fischer 344 rats and B6C3F(1) mice in two-year carcinogenicity studies: A National Toxicology Program update. Toxicol. Pathol. 26 (1998) 428-441
    • (1998) Toxicol. Pathol. , vol.26 , pp. 428-441
    • Haseman, J.K.1    Hailey, J.R.2    Morris, R.W.3
  • 40
    • 0242721397 scopus 로고    scopus 로고
    • Effect of diet and animal care/housing protocols on body weight, survival, tumor incidences, and nephropathy severity of F344 rats in chronic studies
    • Haseman J.K., Ney E., Nyska A., and Rao G.N. Effect of diet and animal care/housing protocols on body weight, survival, tumor incidences, and nephropathy severity of F344 rats in chronic studies. Toxicol. Pathol. 31 (2003) 674-681
    • (2003) Toxicol. Pathol. , vol.31 , pp. 674-681
    • Haseman, J.K.1    Ney, E.2    Nyska, A.3    Rao, G.N.4
  • 41
    • 0000747053 scopus 로고
    • Carboxylesterases and amidases
    • Jakoby W.B., Bend J.R., and Caldwell J. (Eds), Academic Press, New York
    • Heymann E. Carboxylesterases and amidases. In: Jakoby W.B., Bend J.R., and Caldwell J. (Eds). Enzymatic Basis of Detoxication. second ed. (1980), Academic Press, New York 291-323
    • (1980) Enzymatic Basis of Detoxication. second ed. , pp. 291-323
    • Heymann, E.1
  • 42
    • 0015327776 scopus 로고
    • Dehydrogenation of dl-methylphenylcarbinol in the rat
    • Hopkins R.P., Borge P.A., and Callaghan P. Dehydrogenation of dl-methylphenylcarbinol in the rat. Biochem. J. 127 2 (1972) 26-27
    • (1972) Biochem. J. , vol.127 , Issue.2 , pp. 26-27
    • Hopkins, R.P.1    Borge, P.A.2    Callaghan, P.3
  • 44
    • 0024313866 scopus 로고
    • Negative micronucleus tests on caprolactam and benzoin in ICR/JCL male mice
    • Ishidate Jr. M., and Odagiri Y. Negative micronucleus tests on caprolactam and benzoin in ICR/JCL male mice. Mutat. Res. 224 (1989) 357-359
    • (1989) Mutat. Res. , vol.224 , pp. 357-359
    • Ishidate Jr., M.1    Odagiri, Y.2
  • 45
    • 0000014818 scopus 로고
    • The in vitro chromosomal aberration test using Chinese hamster lung (CHL) fibroblast cells in culture
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Ishidate Jr. M., and Sofuni T. The in vitro chromosomal aberration test using Chinese hamster lung (CHL) fibroblast cells in culture. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 427-432
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 427-432
    • Ishidate Jr., M.1    Sofuni, T.2
  • 47
    • 33845203972 scopus 로고    scopus 로고
    • A combined repeated dose toxicity study and reproduction/developmental screening study in Sprague-Dawley rats with acetophenone (OECD Guideline No. 422)
    • Kapp R.W., Thorsrud B.A., Moffatt W.J., and Lawton L. A combined repeated dose toxicity study and reproduction/developmental screening study in Sprague-Dawley rats with acetophenone (OECD Guideline No. 422). The Toxicol. 72 S-1 (2003) 76-77
    • (2003) The Toxicol. , vol.72 , Issue.SUPPL.-1 , pp. 76-77
    • Kapp, R.W.1    Thorsrud, B.A.2    Moffatt, W.J.3    Lawton, L.4
  • 48
    • 0016232196 scopus 로고
    • Hydroxyacetophenone: urinary metobolites of ethylbenzene and acetophenone in the rabbit
    • Kiese M., and Lenk W. Hydroxyacetophenone: urinary metobolites of ethylbenzene and acetophenone in the rabbit. Xenobiotica 4 (1974) 337-343
    • (1974) Xenobiotica , vol.4 , pp. 337-343
    • Kiese, M.1    Lenk, W.2
  • 49
    • 0036206004 scopus 로고    scopus 로고
    • Immunolocalization of multispecific organic anion transporters, OAT1 OAT2, and OAT3, in rat kidney
    • Kojima R., Sekine T., Kawachi M., Cha S.H., Suzuki Y., and Endou H. Immunolocalization of multispecific organic anion transporters, OAT1 OAT2, and OAT3, in rat kidney. J. Am. Soc. Nephrol. 13 (2002) 848-857
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 848-857
    • Kojima, R.1    Sekine, T.2    Kawachi, M.3    Cha, S.H.4    Suzuki, Y.5    Endou, H.6
  • 50
    • 0007663849 scopus 로고
    • Tests for the induction of sister chromatid exchanges in Chinese hamster ovary (CHO) cells in culture
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Lane A.M., Phillips B.J., and Anderson D. Tests for the induction of sister chromatid exchanges in Chinese hamster ovary (CHO) cells in culture. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 451-455
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 451-455
    • Lane, A.M.1    Phillips, B.J.2    Anderson, D.3
  • 51
    • 0001664249 scopus 로고
    • The induction of gene mutations in the mouse lymphoma L5178Y/TK+/-assay and the Chinese hamster V79/HGRPT
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Lee C.G., and Webber T.D. The induction of gene mutations in the mouse lymphoma L5178Y/TK+/-assay and the Chinese hamster V79/HGRPT. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 547-554
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 547-554
    • Lee, C.G.1    Webber, T.D.2
  • 52
    • 33845215395 scopus 로고    scopus 로고
    • Leegwater, D.C., vanStraten, S., 1974. In vitro study on the hydrolysis of twenty-six organic esters by pancreatin. Central Institute for Nutrition and Food Research. Private communication to Flavor and Extract Manufacturers Association, Washington, DC, USA.
  • 53
    • 0014989764 scopus 로고
    • Reduction of ketones in liver cytosol
    • Leibman K.C. Reduction of ketones in liver cytosol. Xenobiotica 1 (1971) 97-104
    • (1971) Xenobiotica , vol.1 , pp. 97-104
    • Leibman, K.C.1
  • 54
    • 33845217293 scopus 로고    scopus 로고
    • Levenstein, I., 1973. Acute oral toxicity reports on rats. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 55
    • 33845220537 scopus 로고    scopus 로고
    • Levenstein, I., 1976. Acute oral toxicity study in rats and acute dermal toxicity study in rabbits. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 56
    • 33845220536 scopus 로고    scopus 로고
    • Levenstein, I., Wolven, A.M., 1972. Acute toxicity studies in rats and in rabbits. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 59
    • 1842617483 scopus 로고    scopus 로고
    • Chemically induce renal tubule tumors in the laboratory rat and mouse: review of the NCI/NTP database and categorization of renal carcinogens based on mechanistic information
    • Lock E.A., and Hard G.C. Chemically induce renal tubule tumors in the laboratory rat and mouse: review of the NCI/NTP database and categorization of renal carcinogens based on mechanistic information. Crit. Rev. Toxicol. 34 (2004) 211-299
    • (2004) Crit. Rev. Toxicol. , vol.34 , pp. 211-299
    • Lock, E.A.1    Hard, G.C.2
  • 61
    • 0023083990 scopus 로고
    • Liver lesions in B6C3F1 mice: The National Toxicology Program, experience and position
    • Maronpot R.R., Haseman J.K., Boorman G.A., Eustis S.E., Rao G.N., and Huff J.E. Liver lesions in B6C3F1 mice: The National Toxicology Program, experience and position. Arch. Toxicol. suppl. 10 (1987) 10-26
    • (1987) Arch. Toxicol. , Issue.SUPPL. 10 , pp. 10-26
    • Maronpot, R.R.1    Haseman, J.K.2    Boorman, G.A.3    Eustis, S.E.4    Rao, G.N.5    Huff, J.E.6
  • 63
    • 0015857126 scopus 로고
    • Effect of phenobarbitol treatment on the stereochemistry of the in vitro metabolism of ethylbenzene
    • Maylin G.A., Cooper M.J., and Anders M.W. Effect of phenobarbitol treatment on the stereochemistry of the in vitro metabolism of ethylbenzene. J. Med. Chem. 16 (1973) 606-610
    • (1973) J. Med. Chem. , vol.16 , pp. 606-610
    • Maylin, G.A.1    Cooper, M.J.2    Anders, M.W.3
  • 64
    • 0024404474 scopus 로고
    • Caprolactam and benzoin: Tests for induction of chromosome aberrations and SCEs in mouse bone marrow
    • McFee A.F., and Lowe K.W. Caprolactam and benzoin: Tests for induction of chromosome aberrations and SCEs in mouse bone marrow. Mutat. Res. 224 (1989) 347-350
    • (1989) Mutat. Res. , vol.224 , pp. 347-350
    • McFee, A.F.1    Lowe, K.W.2
  • 65
    • 0018756732 scopus 로고
    • Assay of 855 test chemicals in ten tester strains using a new modification of Ames test for bacterial mutagens
    • McMahon R.E., Cline J.C., and Thompson C.Z. Assay of 855 test chemicals in ten tester strains using a new modification of Ames test for bacterial mutagens. Cancer Res. 39 (1979) 682-693
    • (1979) Cancer Res. , vol.39 , pp. 682-693
    • McMahon, R.E.1    Cline, J.C.2    Thompson, C.Z.3
  • 66
    • 33845195885 scopus 로고    scopus 로고
    • Minner Jr., R.J., 1977. Comparative acute toxicity studies in the female rat with five synthetic musk chemicals. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 67
    • 33845203973 scopus 로고    scopus 로고
    • Moreno, O.M., 1973. Acute toxicity studies on rats and rabbits. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 68
    • 33845194123 scopus 로고    scopus 로고
    • Moreno, O.M., 1977. Acute toxicity study in rats, rabbits and guinea pigs. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 69
    • 33845200788 scopus 로고    scopus 로고
    • Moreno, O.M., 1982. Acute intraperitoneal toxicity study in rats with musk ambrette 5% in PEA. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 71
    • 0000776249 scopus 로고
    • Assays for the induction of gene mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells in culture
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Myhr B., Bowers L., and Caspary W.J. Assays for the induction of gene mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells in culture. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 555-568
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 555-568
    • Myhr, B.1    Bowers, L.2    Caspary, W.J.3
  • 72
    • 0034619702 scopus 로고    scopus 로고
    • Metabolism and toxicology of benzophenone in isolated rat hepatocytes and estrogenic activity of its metabolites in MCF-7 cells
    • Nakagawa Y., Suzuki T., and Tayama S. Metabolism and toxicology of benzophenone in isolated rat hepatocytes and estrogenic activity of its metabolites in MCF-7 cells. Toxicology 156 (2000) 27-36
    • (2000) Toxicology , vol.156 , pp. 27-36
    • Nakagawa, Y.1    Suzuki, T.2    Tayama, S.3
  • 73
    • 33845233318 scopus 로고    scopus 로고
    • National Academy of Sciences (NAS), 1970. Evaluating the Safety of Food Chemicals. Washington, DC.
  • 74
    • 33845199095 scopus 로고    scopus 로고
    • National Academy of Sciences (NAS), 1972. Evaluating the Safety of Food Chemicals. Washington, DC.
  • 75
    • 33845208798 scopus 로고    scopus 로고
    • National Academy of Sciences (NAS), 1982. Evaluating the Safety of Food Chemicals. Washington, DC.
  • 76
    • 33845218203 scopus 로고    scopus 로고
    • National Academy of Sciences (NAS), 1987. Evaluating the Safety of Food Chemicals. Washington, DC.
  • 77
    • 33845222700 scopus 로고    scopus 로고
    • National Toxicology Program (NTP), 1980. Bioassay of benzoin for possible carcinogenicity (CAS No. 119-53-9). NCI-CG-TR-204; NTP-80-9. National Toxicology Program, Research Triangle Park, NC. Available from: .
  • 78
    • 33845222516 scopus 로고    scopus 로고
    • National Toxicology Program (NTP), 1990. Toxicology and carcinogenesis studies of alpha-methylbenzyl alcohol (CAS No. 98-85-1) in F344/N rats and B6C3F1 mice (gavage studies). NTP-TR-369; PB-89-2824. National Toxicology Program, Research Triangle Park, NC. Available from: .
  • 79
    • 33845198314 scopus 로고    scopus 로고
    • National Toxicology Program (NTP), 2000. NTP Technical report on the toxicity studies of benzophenone (CAS No. 119-61-9) administered in feed to F344 rats and B6C3F1 mice. National Toxicology Program, NH Publication No. 00-3943.
  • 80
    • 33845201682 scopus 로고    scopus 로고
    • National Toxicology Program (NTP), 2002. Developmental toxicity evaluation for benzophenone (CAS No. 119-61-9) administered by gavage to Sprague-Dawley (CD) rats on gestational days 6 through 19. NTP Study No. TER-98-005. National Toxicology Program, Research Triangle Park, NC.
  • 81
    • 33845216617 scopus 로고    scopus 로고
    • National Toxicology Program (NTP), 2004. Toxicology and carcinogenesis studies of benzophenone (CAS No. 119-61-9) in F344/N rats and B6C3F1 Mice (Feed Studies). NTP TR 533. NIH Publication No. 05-4469. National Toxicology Program, Research Triangle Park, NC. Available from: .
  • 82
    • 33845226544 scopus 로고    scopus 로고
    • National Toxicology Program (NTP), 2006. Toxicology and carcinogenesis studies of benzophenone (CAS No. 119-61-9) in F344/N rats and B6C3F1 mice. NTP TR 533. NIH Publication No. 06-4469. National Toxicology Program, Research Triangle Park, NC.
  • 83
    • 0023223086 scopus 로고
    • Prodrugs as drugs delivery systems. 68. Chemical and plasma-catalyzed hydrolysis of various esters of benzoic acid: A reference system for designing prodrug esters of carboxylic acid agents
    • Nielson N.M., and Bundgaard H. Prodrugs as drugs delivery systems. 68. Chemical and plasma-catalyzed hydrolysis of various esters of benzoic acid: A reference system for designing prodrug esters of carboxylic acid agents. Int. J. Pharmacol. 39 (1987) 75-85
    • (1987) Int. J. Pharmacol. , vol.39 , pp. 75-85
    • Nielson, N.M.1    Bundgaard, H.2
  • 84
    • 33845218441 scopus 로고    scopus 로고
    • Nijssen, B., van Ingen-Visscher, K., Donders, J., 2005. Volatile Compounds in Food 8.1. Centraal Instituut Voor Voedingsonderzioek TNO. Zeist, The Netherlands. Available from: .
  • 85
    • 0022383833 scopus 로고
    • Mutagenicity tests on organic chemical contaminants in city water and related compounds. I. Bacterial mutagenicity tests
    • Nohmi T., Miyata R., Yoshikawa K., and Ishidate Jr. M. Mutagenicity tests on organic chemical contaminants in city water and related compounds. I. Bacterial mutagenicity tests. Eisei Shikenjo Hokoku 103 60 (1985) 60-64
    • (1985) Eisei Shikenjo Hokoku , vol.103 , Issue.60 , pp. 60-64
    • Nohmi, T.1    Miyata, R.2    Yoshikawa, K.3    Ishidate Jr., M.4
  • 87
    • 0000776250 scopus 로고
    • Tests for the induction of forward mutation at the thymidine kinase locus of L5178Y mouse lymphoma cells in culture
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Oberly T.J., Bewsey B.J., and Probst G.S. Tests for the induction of forward mutation at the thymidine kinase locus of L5178Y mouse lymphoma cells in culture. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 569-582
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 569-582
    • Oberly, T.J.1    Bewsey, B.J.2    Probst, G.S.3
  • 88
  • 89
    • 0007611936 scopus 로고
    • Tests for effects on mitosis and the mitotic spindle in Chinese hamster primary liver cells (CH1-L) in culture
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Parry E.M. Tests for effects on mitosis and the mitotic spindle in Chinese hamster primary liver cells (CH1-L) in culture. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 479-485
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 479-485
    • Parry, E.M.1
  • 90
    • 33845226827 scopus 로고    scopus 로고
    • Posner, S., 1971. Report on alpha-methylbenzyl acetate to RIFM. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 91
    • 0014545649 scopus 로고
    • Summaries of toxicological data. Toxicological tests on flavoring matters
    • Posternak J.M., Linder A., and Vodoz C.A. Summaries of toxicological data. Toxicological tests on flavoring matters. Food Cosmet. Toxicol. 7 (1969) 405-407
    • (1969) Food Cosmet. Toxicol. , vol.7 , pp. 405-407
    • Posternak, J.M.1    Linder, A.2    Vodoz, C.A.3
  • 92
    • 0020356699 scopus 로고
    • Stereospecific metabolic reduction of ketones
    • Prelusky D.B., Coutts R.T., and Pasutto F.M. Stereospecific metabolic reduction of ketones. J. Pharm. Sci. 71 (1982) 1390-1393
    • (1982) J. Pharm. Sci. , vol.71 , pp. 1390-1393
    • Prelusky, D.B.1    Coutts, R.T.2    Pasutto, F.M.3
  • 93
    • 0020322606 scopus 로고
    • Evaluation, using Salmonella Typhimurium; of the mutagenicity of seven chemicals found in cosmetics
    • Prival M.J., Sheldon Jr. A.T., and Popkin D. Evaluation, using Salmonella Typhimurium; of the mutagenicity of seven chemicals found in cosmetics. Food Chem.Toxicol. 20 (1982) 427-432
    • (1982) Food Chem.Toxicol. , vol.20 , pp. 427-432
    • Prival, M.J.1    Sheldon Jr., A.T.2    Popkin, D.3
  • 94
    • 0000493716 scopus 로고
    • Tests for the induction of DNA-repair synthesis in primary cultures of adult rat hepatocytes
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Probst G.S., and Hill L.E. Tests for the induction of DNA-repair synthesis in primary cultures of adult rat hepatocytes. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 381-386
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 381-386
    • Probst, G.S.1    Hill, L.E.2
  • 95
    • 33845221935 scopus 로고
    • Quantitative studies of beta-oxidation. II. The metabolism of phenylvaleric acid, phenyl-alpha, beta-pentenic acid, phenyl-beta-gamma-pentenic acid, mandelic acid, phenyl-beta-hydroxypropionic acid and acetophenone in dogs
    • Quick A.J. Quantitative studies of beta-oxidation. II. The metabolism of phenylvaleric acid, phenyl-alpha, beta-pentenic acid, phenyl-beta-gamma-pentenic acid, mandelic acid, phenyl-beta-hydroxypropionic acid and acetophenone in dogs. J. Biol. Chem. 80 (1928) 515-526
    • (1928) J. Biol. Chem. , vol.80 , pp. 515-526
    • Quick, A.J.1
  • 96
    • 0342284771 scopus 로고
    • Markers of renal function and injury
    • Loeb W.F., and Quimby F.W. (Eds), Pergamon Press, Inc., New York
    • Ragan H.A. Markers of renal function and injury. In: Loeb W.F., and Quimby F.W. (Eds). The Clinical Chemistry of Laboratory Animals (1989), Pergamon Press, Inc., New York 321-343
    • (1989) The Clinical Chemistry of Laboratory Animals , pp. 321-343
    • Ragan, H.A.1
  • 97
    • 33845212661 scopus 로고    scopus 로고
    • Reagan, E.L., Becci, P.J., 1984. Acute oral LD50 study of 3-benzyl-4-heptanone in Sprague-Dawley rats. Unpublished report to the Flavor and Extract Manufacturers Association, Washington, DC, USA.
  • 99
    • 0013927535 scopus 로고
    • Choleretic activity of 3-(1-benzyl-2-oxocyclohexyl)propionic acid
    • Riva M., Pacchiano F., and Bonacina F. Choleretic activity of 3-(1-benzyl-2-oxocyclohexyl)propionic acid. Arch. Int. Pharmacodyn. Ther. 162 (1966) 54-68
    • (1966) Arch. Int. Pharmacodyn. Ther. , vol.162 , pp. 54-68
    • Riva, M.1    Pacchiano, F.2    Bonacina, F.3
  • 100
    • 0000377586 scopus 로고
    • Studies in detoxication. 74. The metabolism of benzhydrol, benzophenone and p-hydroxybenzophenone
    • Robinson D. Studies in detoxication. 74. The metabolism of benzhydrol, benzophenone and p-hydroxybenzophenone. Biochem. J. 68 (1958) 584-586
    • (1958) Biochem. J. , vol.68 , pp. 584-586
    • Robinson, D.1
  • 101
    • 33845202785 scopus 로고
    • Pharmacological study of synthetic choleretics. II. Effect on the composition of the bile. III. Toxicity
    • Rohrbach P., and Robineau M. Pharmacological study of synthetic choleretics. II. Effect on the composition of the bile. III. Toxicity. Arch. Int. Pharmacodyn. Ther. 116 (1958) 154-169
    • (1958) Arch. Int. Pharmacodyn. Ther. , vol.116 , pp. 154-169
    • Rohrbach, P.1    Robineau, M.2
  • 102
    • 33845198089 scopus 로고    scopus 로고
    • Russell, T., 1973. Acute oral and dermal toxicity studies. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA.
  • 103
    • 0030793860 scopus 로고    scopus 로고
    • Absorption, disposition, and metabolism of trans-methyl styryl ketone in female B6C3F1 mice
    • Sauer J.M., Bao J.Q., Smith R.L., Kuester R.K., Mayersohn M., and Sipes I.G. Absorption, disposition, and metabolism of trans-methyl styryl ketone in female B6C3F1 mice. Drug Metab. Dispos. 25 (1997) 1184-1190
    • (1997) Drug Metab. Dispos. , vol.25 , pp. 1184-1190
    • Sauer, J.M.1    Bao, J.Q.2    Smith, R.L.3    Kuester, R.K.4    Mayersohn, M.5    Sipes, I.G.6
  • 104
    • 0031008491 scopus 로고    scopus 로고
    • Oral and topical absorption, disposition kinetics and the metabolic fate of trans-methyl styryl ketone in the male Fischer 344 rat
    • Sauer J.M., Smith R.L., Bao J., Katting M.J., Kuester R.K., McClure T.D., Mayersohn M., and Sipes I.G. Oral and topical absorption, disposition kinetics and the metabolic fate of trans-methyl styryl ketone in the male Fischer 344 rat. Drug Metab. Dispos. 25 (1997) 732-739
    • (1997) Drug Metab. Dispos. , vol.25 , pp. 732-739
    • Sauer, J.M.1    Smith, R.L.2    Bao, J.3    Katting, M.J.4    Kuester, R.K.5    McClure, T.D.6    Mayersohn, M.7    Sipes, I.G.8
  • 105
    • 0036865804 scopus 로고    scopus 로고
    • The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats
    • Seely J.C., Haseman J.K., Nyska A., Wolf D.C., Everitt J.I., and Hailey J.R. The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats. Toxicol. Pathol. 30 (2002) 681-686
    • (2002) Toxicol. Pathol. , vol.30 , pp. 681-686
    • Seely, J.C.1    Haseman, J.K.2    Nyska, A.3    Wolf, D.C.4    Everitt, J.I.5    Hailey, J.R.6
  • 106
    • 0021993049 scopus 로고
    • Acute oral toxicity and repellency of 933 chemicals to house and deer mice
    • Schafer Jr. E.W., and Bowles Jr. W.A. Acute oral toxicity and repellency of 933 chemicals to house and deer mice. Arch. Environ. Contam. Toxicol. 14 (1985) 111-129
    • (1985) Arch. Environ. Contam. Toxicol. , vol.14 , pp. 111-129
    • Schafer Jr., E.W.1    Bowles Jr., W.A.2
  • 107
    • 0027526525 scopus 로고
    • Evaluation of a three-exposure mouse bone marrow micronucleus protocol: results with 49 chemicals
    • Shelby M.D., Erexson G.L., Hook G.L., and Tice R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: results with 49 chemicals. Environ. Mol. Mutagen. 21 (1993) 160-179
    • (1993) Environ. Mol. Mutagen. , vol.21 , pp. 160-179
    • Shelby, M.D.1    Erexson, G.L.2    Hook, G.L.3    Tice, R.R.4
  • 108
    • 0024357807 scopus 로고
    • An evaluation of caprolactam and benzoin in the mouse micronucleus test
    • Sheldon T. An evaluation of caprolactam and benzoin in the mouse micronucleus test. Mutat. Res. 224 (1989) 351-355
    • (1989) Mutat. Res. , vol.224 , pp. 351-355
    • Sheldon, T.1
  • 109
    • 0000160802 scopus 로고
    • Recent progress in the consideration of flavoring ingredients under the food additives amendment. 16. GRAS substances
    • Smith R.L., and Ford R.A. Recent progress in the consideration of flavoring ingredients under the food additives amendment. 16. GRAS substances. Food Technol. 47 (1993) 104-117
    • (1993) Food Technol. , vol.47 , pp. 104-117
    • Smith, R.L.1    Ford, R.A.2
  • 110
    • 33845206787 scopus 로고
    • Studies in detoxication. 59. The metabolism of alkylbenzenes: the biological reduction of ketones derived from alkylbenzenes
    • Smith J.N., Smithies R.H., and Williams R.T. Studies in detoxication. 59. The metabolism of alkylbenzenes: the biological reduction of ketones derived from alkylbenzenes. Biochem. J. 57 (1954) 74-76
    • (1954) Biochem. J. , vol.57 , pp. 74-76
    • Smith, J.N.1    Smithies, R.H.2    Williams, R.T.3
  • 111
    • 0345089215 scopus 로고
    • Studies in detoxication. 56. The metabolism of alkylbenzenes: stereochemical aspects of the biological hydroxylation of ethylbenzene to methylphenylcarbinol
    • Smith J.N., Smithies R.H., and Williams R.T. Studies in detoxication. 56. The metabolism of alkylbenzenes: stereochemical aspects of the biological hydroxylation of ethylbenzene to methylphenylcarbinol. Biochem. J. 56 (1954) 320-324
    • (1954) Biochem. J. , vol.56 , pp. 320-324
    • Smith, J.N.1    Smithies, R.H.2    Williams, R.T.3
  • 112
    • 0010754915 scopus 로고
    • The place of the range finding test in the industrial toxicology laboratory
    • Smyth Jr. H.F., and Carpenter C.P. The place of the range finding test in the industrial toxicology laboratory. J. Ind. Hyg. Toxicol. 26 (1944) 269-273
    • (1944) J. Ind. Hyg. Toxicol. , vol.26 , pp. 269-273
    • Smyth Jr., H.F.1    Carpenter, C.P.2
  • 113
    • 84958050403 scopus 로고
    • Further experience with the range finding test in the industrial toxicology laboratory
    • Smyth Jr. H.F., and Carpenter C.P. Further experience with the range finding test in the industrial toxicology laboratory. J. Ind. Hyg. Toxicol. 30 (1948) 63-68
    • (1948) J. Ind. Hyg. Toxicol. , vol.30 , pp. 63-68
    • Smyth Jr., H.F.1    Carpenter, C.P.2
  • 114
    • 0014490377 scopus 로고
    • An exploration of joint toxic action: twenty-seven industrial chemicals incubated in rats in all possible pairs
    • Smyth Jr. H.F., Weil C.S., West J.S., and Carpenter C.P. An exploration of joint toxic action: twenty-seven industrial chemicals incubated in rats in all possible pairs. Toxicol. Appl. Pharmacol. 14 (1969) 340-347
    • (1969) Toxicol. Appl. Pharmacol. , vol.14 , pp. 340-347
    • Smyth Jr., H.F.1    Weil, C.S.2    West, J.S.3    Carpenter, C.P.4
  • 115
    • 0022356046 scopus 로고
    • Mutagenicity tests on organic chemical contaminants in city water and related compounds. II. Chromosome aberration tests in cultured mammalian cells
    • Sofuni T., Hayashi M., Matsuoka A., Sawada M., Hatanaka M., and Ishidate M. Mutagenicity tests on organic chemical contaminants in city water and related compounds. II. Chromosome aberration tests in cultured mammalian cells. Eisei Shikenjo Hokoku 103 (1985) 64-75
    • (1985) Eisei Shikenjo Hokoku , vol.103 , pp. 64-75
    • Sofuni, T.1    Hayashi, M.2    Matsuoka, A.3    Sawada, M.4    Hatanaka, M.5    Ishidate, M.6
  • 116
    • 0002460382 scopus 로고
    • Consumption Ratio and food predominance of flavoring materials
    • Stofberg J., and Grundschober F. Consumption Ratio and food predominance of flavoring materials. Perfumer Flavorist 12 (1987) 27-68
    • (1987) Perfumer Flavorist , vol.12 , pp. 27-68
    • Stofberg, J.1    Grundschober, F.2
  • 117
    • 0022410028 scopus 로고
    • The consumption ratio of flavoring materials: a mechanism for setting priorities for safety evaluation
    • Stofberg J., and Kirschman J.C. The consumption ratio of flavoring materials: a mechanism for setting priorities for safety evaluation. Food Chem. Toxicol. 23 (1985) 857-860
    • (1985) Food Chem. Toxicol. , vol.23 , pp. 857-860
    • Stofberg, J.1    Kirschman, J.C.2
  • 118
    • 0000776251 scopus 로고
    • Assays for the induction of gene mutations at the thymidine kinase and the Na+/K+ ATPase loci in two different mouse lymphoma cell lines in culture
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Styles J.A., Clay P., and Cross M.F. Assays for the induction of gene mutations at the thymidine kinase and the Na+/K+ ATPase loci in two different mouse lymphoma cell lines in culture. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 587-596
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 587-596
    • Styles, J.A.1    Clay, P.2    Cross, M.F.3
  • 119
    • 0016907517 scopus 로고
    • Reaction pathways of in vivo stereoselective conversion of ethylbenzene to (-)-mandelic acid
    • Sullivan H.R., Miller W.M., and McMahon R.E. Reaction pathways of in vivo stereoselective conversion of ethylbenzene to (-)-mandelic acid. Xenobiotica 6 (1976) 49-54
    • (1976) Xenobiotica , vol.6 , pp. 49-54
    • Sullivan, H.R.1    Miller, W.M.2    McMahon, R.E.3
  • 120
    • 84914391522 scopus 로고
    • Behavior of aliphatic-aromatic ketones in the animal body
    • Thierfelder H., and Daiber K. Behavior of aliphatic-aromatic ketones in the animal body. Hoppe-Seyler's Z. Physiol. Chem. 130 (1923) 380-396
    • (1923) Hoppe-Seyler's Z. Physiol. Chem. , vol.130 , pp. 380-396
    • Thierfelder, H.1    Daiber, K.2
  • 121
  • 122
    • 33845218842 scopus 로고    scopus 로고
    • Trubek Laboratories, Inc., 1956. Sub-acute oral toxicity test of 4-(p-methoxyphenyl)-2-butanone in rats. Unpublished report to the Flavor and Extract Manufacturers Association, Washington, DC, USA.
  • 123
    • 33845188995 scopus 로고    scopus 로고
    • Trubek Laboratories, Inc., 1958. Toxicological screening of 4-(p-methoxy phenyl)-2-butanone in rats. Class XIII. Unpublished report to the Flavor and Extract Manufacturers Association, Washington, DC, USA.
  • 124
    • 33845225913 scopus 로고    scopus 로고
    • Trubek Laboratories, Inc., 1964. Acute oral LD50 of 4-phenyl-3-buten-2-one in rats and sensitization test of 4-phenyl-3-buten-2-one in guinea pigs. Unpublished report to the Flavor and Extract Manufacturers Association, Washington, DC, USA.
  • 125
    • 0020974084 scopus 로고
    • Study of artificial flavoring substances for mutagenicity in the Salmonella/microsome, basic and micronucleus tests
    • Wild D., King M.T., Gocke E., and Eckhardt K. Study of artificial flavoring substances for mutagenicity in the Salmonella/microsome, basic and micronucleus tests. Food Chem. Toxicol. 21 (1983) 707-719
    • (1983) Food Chem. Toxicol. , vol.21 , pp. 707-719
    • Wild, D.1    King, M.T.2    Gocke, E.3    Eckhardt, K.4
  • 126
    • 0024342642 scopus 로고
    • Assessment of unscheduled DNA synthesis in Fischer 344 rat pachytene spermatocytes exposed to caprolactam or benzoin in vivo
    • Working P.K. Assessment of unscheduled DNA synthesis in Fischer 344 rat pachytene spermatocytes exposed to caprolactam or benzoin in vivo. Mutat. Res. 224 (1989) 365-368
    • (1989) Mutat. Res. , vol.224 , pp. 365-368
    • Working, P.K.1
  • 127
    • 0001519062 scopus 로고
    • Tests with a preincubation modification of the Salmonella/microsome assay
    • De Serres F.J., and Ashby J. (Eds), Elsevier/North Holland, New York
    • Zeiger E., and Haworth S. Tests with a preincubation modification of the Salmonella/microsome assay. In: De Serres F.J., and Ashby J. (Eds). Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program vol. 5 (1985), Elsevier/North Holland, New York 187-199
    • (1985) Evaluation of Short-Term Tests for Carcinogens: Report of the International Collaborative Program , vol.5 , pp. 187-199
    • Zeiger, E.1    Haworth, S.2


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