-
1
-
-
55149094739
-
Interleukin-10: new perspectives on an old cytokine
-
Mosser DM, Zhang X, (2008) Interleukin-10: new perspectives on an old cytokine. Immunological Reviews 226: 205-218.
-
(2008)
Immunological Reviews
, vol.226
, pp. 205-218
-
-
Mosser, D.M.1
Zhang, X.2
-
2
-
-
0027204621
-
Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production
-
Del Prete G, De Carli M, Almerigogna F, Giudizi MG, Biagiotti R, et al. (1993) Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol 150: 353-360.
-
(1993)
J Immunol
, vol.150
, pp. 353-360
-
-
Del Prete, G.1
de Carli, M.2
Almerigogna, F.3
Giudizi, M.G.4
Biagiotti, R.5
-
3
-
-
0030058433
-
Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells
-
Groux H, Bigler M, de Vries JE, Roncarolo MG, (1996) Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells. J Exp Med 184: 19-29.
-
(1996)
J Exp Med
, vol.184
, pp. 19-29
-
-
Groux, H.1
Bigler, M.2
de Vries, J.E.3
Roncarolo, M.G.4
-
4
-
-
0034039840
-
IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway
-
Joss A, Akdis M, Faith A, Blaser K, Akdis CA, (2000) IL-10 directly acts on T cells by specifically altering the CD28 co-stimulation pathway. Eur J Immunol 30: 1683-1690.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1683-1690
-
-
Joss, A.1
Akdis, M.2
Faith, A.3
Blaser, K.4
Akdis, C.A.5
-
5
-
-
0037018104
-
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
Barrat FJ, Cua DJ, Boonstra A, Richards DF, Crain C, et al. (2002) In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 195: 603-616.
-
(2002)
J Exp Med
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
Cua, D.J.2
Boonstra, A.3
Richards, D.F.4
Crain, C.5
-
6
-
-
0035339884
-
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells
-
Levings MK, Sangregorio R, Galbiati F, Squadrone S, de Waal Malefyt R, et al. (2001) IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells. J Immunol 166: 5530-5539.
-
(2001)
J Immunol
, vol.166
, pp. 5530-5539
-
-
Levings, M.K.1
Sangregorio, R.2
Galbiati, F.3
Squadrone, S.4
de Waal Malefyt, R.5
-
7
-
-
70350464351
-
Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis
-
Murai M, Turovskaya O, Kim G, Madan R, Karp CL, et al. (2009) Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat Immunol 10: 1178-1184.
-
(2009)
Nat Immunol
, vol.10
, pp. 1178-1184
-
-
Murai, M.1
Turovskaya, O.2
Kim, G.3
Madan, R.4
Karp, C.L.5
-
8
-
-
77649184739
-
The regulation of IL-10 production by immune cells
-
Saraiva M, O'Garra A, (2010) The regulation of IL-10 production by immune cells. Nat Rev Immunol 10: 170-181.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 170-181
-
-
Saraiva, M.1
O'Garra, A.2
-
9
-
-
47249134619
-
Strategies for use of IL-10 or its antagonists in human disease
-
O'Garra A, Barrat FJ, Castro AG, Vicari A, Hawrylowicz C, (2008) Strategies for use of IL-10 or its antagonists in human disease. Immunological Reviews 223: 114-131.
-
(2008)
Immunological Reviews
, vol.223
, pp. 114-131
-
-
O'Garra, A.1
Barrat, F.J.2
Castro, A.G.3
Vicari, A.4
Hawrylowicz, C.5
-
10
-
-
0034714256
-
Immunology. Therapeutic manipulation of gut flora
-
Shanahan F, (2000) Immunology. Therapeutic manipulation of gut flora. Science 289: 1311-1312.
-
(2000)
Science
, vol.289
, pp. 1311-1312
-
-
Shanahan, F.1
-
11
-
-
0035159581
-
Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis
-
Cua DJ, Hutchins B, LaFace DM, Stohlman SA, Coffman RL, (2001) Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitis. J Immunol 166: 602-608.
-
(2001)
J Immunol
, vol.166
, pp. 602-608
-
-
Cua, D.J.1
Hutchins, B.2
LaFace, D.M.3
Stohlman, S.A.4
Coffman, R.L.5
-
12
-
-
0025673971
-
Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells
-
Go NF, Castle BE, Barrett R, Kastelein R, Dang W, et al. (1990) Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. J Exp Med 172: 1625-1631.
-
(1990)
J Exp Med
, vol.172
, pp. 1625-1631
-
-
Go, N.F.1
Castle, B.E.2
Barrett, R.3
Kastelein, R.4
Dang, W.5
-
13
-
-
0026584291
-
Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes
-
Rousset F, Garcia E, Defrance T, Peronne C, Vezzio N, et al. (1992) Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci U S A 89: 1890-1893.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 1890-1893
-
-
Rousset, F.1
Garcia, E.2
Defrance, T.3
Peronne, C.4
Vezzio, N.5
-
14
-
-
0026563156
-
Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A
-
Defrance T, Vanbervliet B, Briere F, Durand I, Rousset F, et al. (1992) Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J Exp Med 175: 671-682.
-
(1992)
J Exp Med
, vol.175
, pp. 671-682
-
-
Defrance, T.1
Vanbervliet, B.2
Briere, F.3
Durand, I.4
Rousset, F.5
-
15
-
-
0032055224
-
Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells
-
Groux H, Bigler M, de Vries JE, Roncarolo MG, (1998) Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells. J Immunol 160: 3188-3193.
-
(1998)
J Immunol
, vol.160
, pp. 3188-3193
-
-
Groux, H.1
Bigler, M.2
de Vries, J.E.3
Roncarolo, M.G.4
-
16
-
-
0033997779
-
Interleukin-10 Increases Th1 Cytokine Production and Cytotoxic Potential in Human Papillomavirus-Specific CD8+ Cytotoxic T Lymphocytes
-
Santin AD, Hermonat PL, Ravaggi A, Bellone S, Pecorelli S, et al. (2000) Interleukin-10 Increases Th1 Cytokine Production and Cytotoxic Potential in Human Papillomavirus-Specific CD8+ Cytotoxic T Lymphocytes. J Virol 74: 4729-4737.
-
(2000)
J Virol
, vol.74
, pp. 4729-4737
-
-
Santin, A.D.1
Hermonat, P.L.2
Ravaggi, A.3
Bellone, S.4
Pecorelli, S.5
-
17
-
-
0034327736
-
Inhibition of IL-6 and IL-10 signaling and Stat activation by inflammatory and stress pathways
-
Ahmed ST, Ivashkiv LB, (2000) Inhibition of IL-6 and IL-10 signaling and Stat activation by inflammatory and stress pathways. J Immunol 165: 5227-5237.
-
(2000)
J Immunol
, vol.165
, pp. 5227-5237
-
-
Ahmed, S.T.1
Ivashkiv, L.B.2
-
18
-
-
0037606153
-
Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis
-
Ji JD, Tassiulas I, Park-Min KH, Aydin A, Mecklenbrauker I, et al. (2003) Inhibition of interleukin 10 signaling after Fc receptor ligation and during rheumatoid arthritis. J Exp Med 197: 1573-1583.
-
(2003)
J Exp Med
, vol.197
, pp. 1573-1583
-
-
Ji, J.D.1
Tassiulas, I.2
Park-Min, K.H.3
Aydin, A.4
Mecklenbrauker, I.5
-
19
-
-
33645761634
-
Selective regulation of IL-10 signaling and function by zymosan
-
Du Z, Kelly E, Mecklenbrauker I, Agle L, Herrero C, et al. (2006) Selective regulation of IL-10 signaling and function by zymosan. J Immunol 176: 4785-4792.
-
(2006)
J Immunol
, vol.176
, pp. 4785-4792
-
-
Du, Z.1
Kelly, E.2
Mecklenbrauker, I.3
Agle, L.4
Herrero, C.5
-
20
-
-
0842321775
-
Inhibition of IL-10 receptor function in alveolar macrophages by Toll-like receptor agonists
-
Fernandez S, Jose P, Avdiushko MG, Kaplan AM, Cohen DA, (2004) Inhibition of IL-10 receptor function in alveolar macrophages by Toll-like receptor agonists. J Immunol 172: 2613-2620.
-
(2004)
J Immunol
, vol.172
, pp. 2613-2620
-
-
Fernandez, S.1
Jose, P.2
Avdiushko, M.G.3
Kaplan, A.M.4
Cohen, D.A.5
-
21
-
-
0030799157
-
Identification and functional characterization of a second chain of the interleukin-10 receptor complex
-
Kotenko SV, Krause CD, Izotova LS, Pollack BP, Wu W, et al. (1997) Identification and functional characterization of a second chain of the interleukin-10 receptor complex. EMBO J 16: 5894-5903.
-
(1997)
EMBO J
, vol.16
, pp. 5894-5903
-
-
Kotenko, S.V.1
Krause, C.D.2
Izotova, L.S.3
Pollack, B.P.4
Wu, W.5
-
22
-
-
0032536530
-
The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor
-
Spencer SD, Di Marco F, Hooley J, Pitts-Meek S, Bauer M, et al. (1998) The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor. J Exp Med 187: 571-578.
-
(1998)
J Exp Med
, vol.187
, pp. 571-578
-
-
Spencer, S.D.1
Di Marco, F.2
Hooley, J.3
Pitts-Meek, S.4
Bauer, M.5
-
23
-
-
75149114226
-
Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model
-
Pils MC, Pisano F, Fasnacht N, Heinrich JM, Groebe L, et al. (2010) Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model. Eur J Immunol 40: 443-448.
-
(2010)
Eur J Immunol
, vol.40
, pp. 443-448
-
-
Pils, M.C.1
Pisano, F.2
Fasnacht, N.3
Heinrich, J.M.4
Groebe, L.5
-
24
-
-
0029981103
-
Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain
-
Weber-Nordt RM, Riley JK, Greenlund AC, Moore KW, Darnell JE, et al. (1996) Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain. J Biol Chem 271: 27954-27961.
-
(1996)
J Biol Chem
, vol.271
, pp. 27954-27961
-
-
Weber-Nordt, R.M.1
Riley, J.K.2
Greenlund, A.C.3
Moore, K.W.4
Darnell, J.E.5
-
25
-
-
0033523019
-
Interleukin-10 Receptor Signaling through the JAK-STAT Pathway
-
Riley JK, Takeda K, Akira S, Schreiber RD, (1999) Interleukin-10 Receptor Signaling through the JAK-STAT Pathway. Journal of Biological Chemistry 274: 16513-16521.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 16513-16521
-
-
Riley, J.K.1
Takeda, K.2
Akira, S.3
Schreiber, R.D.4
-
26
-
-
33745700364
-
Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response
-
Murray PJ, (2006) Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response. Curr Opin Pharmacol 6: 379-386.
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 379-386
-
-
Murray, P.J.1
-
27
-
-
33751555600
-
General nature of the STAT3-activated anti-inflammatory response
-
El Kasmi KC, Holst J, Coffre M, Mielke L, de Pauw A, et al. (2006) General nature of the STAT3-activated anti-inflammatory response. J Immunol 177: 7880-7888.
-
(2006)
J Immunol
, vol.177
, pp. 7880-7888
-
-
El Kasmi, K.C.1
Holst, J.2
Coffre, M.3
Mielke, L.4
de Pauw, A.5
-
28
-
-
34147095832
-
Expression of constitutively active STAT3 can replicate the cytokine-suppressive activity of interleukin-10 in human primary macrophages
-
Williams LM, Sarma U, Willets K, Smallie T, Brennan F, et al. (2007) Expression of constitutively active STAT3 can replicate the cytokine-suppressive activity of interleukin-10 in human primary macrophages. J Biol Chem 282: 6965-6975.
-
(2007)
J Biol Chem
, vol.282
, pp. 6965-6975
-
-
Williams, L.M.1
Sarma, U.2
Willets, K.3
Smallie, T.4
Brennan, F.5
-
29
-
-
1642432084
-
The Class II cytokine receptor (CRF2) family: overview and patterns of receptor-ligand interactions
-
Langer JA, Cutrone EC, Kotenko S, (2004) The Class II cytokine receptor (CRF2) family: overview and patterns of receptor-ligand interactions. Cytokine Growth Factor Rev 15: 33-48.
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 33-48
-
-
Langer, J.A.1
Cutrone, E.C.2
Kotenko, S.3
-
30
-
-
0035892751
-
Differential IL-10R1 expression plays a critical role in IL-10-mediated immune regulation
-
Ding Y, Qin L, Zamarin D, Kotenko SV, Pestka S, et al. (2001) Differential IL-10R1 expression plays a critical role in IL-10-mediated immune regulation. J Immunol 167: 6884-6892.
-
(2001)
J Immunol
, vol.167
, pp. 6884-6892
-
-
Ding, Y.1
Qin, L.2
Zamarin, D.3
Kotenko, S.V.4
Pestka, S.5
-
31
-
-
0029148046
-
Functional regions of the mouse interleukin-10 receptor cytoplasmic domain
-
Ho AS, Wei SH, Mui AL, Miyajima A, Moore KW, (1995) Functional regions of the mouse interleukin-10 receptor cytoplasmic domain. Mol Cell Biol 15: 5043-5053.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5043-5053
-
-
Ho, A.S.1
Wei, S.H.2
Mui, A.L.3
Miyajima, A.4
Moore, K.W.5
-
32
-
-
33744479975
-
Proteasome-mediated proteolysis of the interleukin-10 receptor is important for signal downregulation
-
Wei SH, Ming-Lum A, Liu Y, Wallach D, Ong CJ, et al. (2006) Proteasome-mediated proteolysis of the interleukin-10 receptor is important for signal downregulation. J Interferon Cytokine Res 26: 281-290.
-
(2006)
J Interferon Cytokine Res
, vol.26
, pp. 281-290
-
-
Wei, S.H.1
Ming-Lum, A.2
Liu, Y.3
Wallach, D.4
Ong, C.J.5
-
33
-
-
0142105396
-
SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor
-
Kumar KG, Tang W, Ravindranath AK, Clark WA, Croze E, et al. (2003) SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor. Embo J 22: 5480-5490.
-
(2003)
Embo J
, vol.22
, pp. 5480-5490
-
-
Kumar, K.G.1
Tang, W.2
Ravindranath, A.K.3
Clark, W.A.4
Croze, E.5
-
34
-
-
58249084172
-
Virus-induced unfolded protein response attenuates antiviral defenses via phosphorylation-dependent degradation of the type I interferon receptor
-
Liu J, HuangFu WC, Kumar KG, Qian J, Casey JP, et al. (2009) Virus-induced unfolded protein response attenuates antiviral defenses via phosphorylation-dependent degradation of the type I interferon receptor. Cell Host Microbe 5: 72-83.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 72-83
-
-
Liu, J.1
HuangFu, W.C.2
Kumar, K.G.3
Qian, J.4
Casey, J.P.5
-
35
-
-
38349075024
-
Ligand-independent pathway that controls stability of interferon alpha receptor
-
Liu J, Plotnikov A, Banerjee A, Suresh Kumar KG, Ragimbeau J, et al. (2008) Ligand-independent pathway that controls stability of interferon alpha receptor. Biochemical and Biophysical Research Communications 367: 388-393.
-
(2008)
Biochemical and Biophysical Research Communications
, vol.367
, pp. 388-393
-
-
Liu, J.1
Plotnikov, A.2
Banerjee, A.3
Suresh Kumar, K.G.4
Ragimbeau, J.5
-
36
-
-
79251574143
-
Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2
-
Zheng H, Qian J, Varghese B, Baker DP, Fuchs S, (2010) Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2. Mol Cell Biol 31: 710-720.
-
(2010)
Mol Cell Biol
, vol.31
, pp. 710-720
-
-
Zheng, H.1
Qian, J.2
Varghese, B.3
Baker, D.P.4
Fuchs, S.5
-
37
-
-
78049234828
-
Melanoma cell-secreted soluble factor that stimulates ubiquitination and degradation of the interferon alpha receptor and attenuates its signaling
-
HuangFu WC, Qian J, Liu C, Rui H, Fuchs SY, (2010) Melanoma cell-secreted soluble factor that stimulates ubiquitination and degradation of the interferon alpha receptor and attenuates its signaling. Pigment Cell Melanoma Res 23: 838-840.
-
(2010)
Pigment Cell Melanoma Res
, vol.23
, pp. 838-840
-
-
HuangFu, W.C.1
Qian, J.2
Liu, C.3
Rui, H.4
Fuchs, S.Y.5
-
38
-
-
79959855146
-
Pathogen Recognition Receptor Signaling Accelerates Phosphorylation-Dependent Degradation of IFNAR1
-
Qian J, Zheng H, HuangFu W-C, Liu J, Carbone CJ, et al. (2011) Pathogen Recognition Receptor Signaling Accelerates Phosphorylation-Dependent Degradation of IFNAR1. PLoS Pathog 7: e1002065.
-
(2011)
PLoS Pathog
, vol.7
-
-
Qian, J.1
Zheng, H.2
HuangFu, W.-C.3
Liu, J.4
Carbone, C.J.5
-
39
-
-
51249113856
-
Cigarette smoking products suppress anti-viral effects of Type I interferon via phosphorylation-dependent downregulation of its receptor
-
HuangFu WC, Liu J, Harty RN, Fuchs SY, (2008) Cigarette smoking products suppress anti-viral effects of Type I interferon via phosphorylation-dependent downregulation of its receptor. FEBS Lett 582: 3206-3210.
-
(2008)
FEBS Lett
, vol.582
, pp. 3206-3210
-
-
HuangFu, W.C.1
Liu, J.2
Harty, R.N.3
Fuchs, S.Y.4
-
40
-
-
1942502180
-
The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer
-
Fuchs SY, Spiegelman VS, Kumar KG, (2004) The many faces of beta-TrCP E3 ubiquitin ligases: reflections in the magic mirror of cancer. Oncogene 23: 2028-2036.
-
(2004)
Oncogene
, vol.23
, pp. 2028-2036
-
-
Fuchs, S.Y.1
Spiegelman, V.S.2
Kumar, K.G.3
-
41
-
-
0042622251
-
Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs
-
Obenauer JC, Cantley LC, Yaffe MB, (2003) Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs. Nucleic Acids Res 31: 3635-3641.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3635-3641
-
-
Obenauer, J.C.1
Cantley, L.C.2
Yaffe, M.B.3
-
42
-
-
0242412335
-
Reprogramming of IL-10 Activity and Signaling by IFN-gamma
-
Herrero C, Hu X, Li WP, Samuels S, Sharif MN, et al. (2003) Reprogramming of IL-10 Activity and Signaling by IFN-gamma. The Journal of Immunology 171: 5034-5041.
-
(2003)
The Journal of Immunology
, vol.171
, pp. 5034-5041
-
-
Herrero, C.1
Hu, X.2
Li, W.P.3
Samuels, S.4
Sharif, M.N.5
-
43
-
-
0027420575
-
A receptor for interleukin 10 is related to interferon receptors
-
Ho AS, Liu Y, Khan TA, Hsu DH, Bazan JF, et al. (1993) A receptor for interleukin 10 is related to interferon receptors. Proc Natl Acad Sci U S A 90: 11267-11271.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 11267-11271
-
-
Ho, A.S.1
Liu, Y.2
Khan, T.A.3
Hsu, D.H.4
Bazan, J.F.5
-
44
-
-
1942453784
-
Negative regulation of prolactin receptor stability and signaling mediated by SCF(beta-TrCP) E3 ubiquitin ligase
-
Li Y, Kumar KG, Tang W, Spiegelman VS, Fuchs SY, (2004) Negative regulation of prolactin receptor stability and signaling mediated by SCF(beta-TrCP) E3 ubiquitin ligase. Mol Cell Biol 24: 4038-4048.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4038-4048
-
-
Li, Y.1
Kumar, K.G.2
Tang, W.3
Spiegelman, V.S.4
Fuchs, S.Y.5
-
45
-
-
34250027624
-
beta-Trcp mediates ubiquitination and degradation of the erythropoietin receptor and controls cell proliferation
-
Meyer L, Deau B, Forejtnikova H, Dumenil D, Margottin-Goguet F, et al. (2007) beta-Trcp mediates ubiquitination and degradation of the erythropoietin receptor and controls cell proliferation. Blood 109: 5215-5222.
-
(2007)
Blood
, vol.109
, pp. 5215-5222
-
-
Meyer, L.1
Deau, B.2
Forejtnikova, H.3
Dumenil, D.4
Margottin-Goguet, F.5
-
46
-
-
77951708374
-
Reconstitution of the RIG-I Pathway Reveals a Signaling Role of Unanchored Polyubiquitin Chains in Innate Immunity
-
Zeng W, Sun L, Jiang X, Chen X, Hou F, et al. (2010) Reconstitution of the RIG-I Pathway Reveals a Signaling Role of Unanchored Polyubiquitin Chains in Innate Immunity. Cell 141: 315-330.
-
(2010)
Cell
, vol.141
, pp. 315-330
-
-
Zeng, W.1
Sun, L.2
Jiang, X.3
Chen, X.4
Hou, F.5
-
47
-
-
0347361537
-
SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase
-
Jin J, Shirogane T, Xu L, Nalepa G, Qin J, et al. (2003) SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase. Genes Dev 17: 3062-3074.
-
(2003)
Genes Dev
, vol.17
, pp. 3062-3074
-
-
Jin, J.1
Shirogane, T.2
Xu, L.3
Nalepa, G.4
Qin, J.5
-
48
-
-
0242497228
-
Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage
-
Busino L, Donzelli M, Chiesa M, Guardavaccaro D, Ganoth D, et al. (2003) Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage. Nature 426: 87-91.
-
(2003)
Nature
, vol.426
, pp. 87-91
-
-
Busino, L.1
Donzelli, M.2
Chiesa, M.3
Guardavaccaro, D.4
Ganoth, D.5
-
49
-
-
34548273636
-
Gamma-Aminobutyric Acid Type B Receptors Are Constitutively Internalized via the Clathrin-dependent Pathway and Targeted to Lysosomes for Degradation
-
Grampp T, Sauter K, Markovic B, Benke D, (2007) Gamma-Aminobutyric Acid Type B Receptors Are Constitutively Internalized via the Clathrin-dependent Pathway and Targeted to Lysosomes for Degradation. J Biol Chem 282: 24157-24165.
-
(2007)
J Biol Chem
, vol.282
, pp. 24157-24165
-
-
Grampp, T.1
Sauter, K.2
Markovic, B.3
Benke, D.4
-
50
-
-
0037926396
-
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking
-
Metzler M, Li B, Gan L, Georgiou J, Gutekunst CA, et al. (2003) Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking. Embo J 22: 3254-3266.
-
(2003)
Embo J
, vol.22
, pp. 3254-3266
-
-
Metzler, M.1
Li, B.2
Gan, L.3
Georgiou, J.4
Gutekunst, C.A.5
-
51
-
-
78650100616
-
Ubiquitin: same molecule, different degradation pathways
-
Clague MJ, Urbe S, (2010) Ubiquitin: same molecule, different degradation pathways. Cell 143: 682-685.
-
(2010)
Cell
, vol.143
, pp. 682-685
-
-
Clague, M.J.1
Urbe, S.2
-
52
-
-
32844471837
-
Two different stages of epidermal growth factor (EGF) receptor endocytosis are sensitive to free ubiquitin depletion produced by proteasome inhibitor MG132
-
Melikova MS, Kondratov KA, Kornilova ES, (2006) Two different stages of epidermal growth factor (EGF) receptor endocytosis are sensitive to free ubiquitin depletion produced by proteasome inhibitor MG132. Cell Biol Int 30: 31-43.
-
(2006)
Cell Biol Int
, vol.30
, pp. 31-43
-
-
Melikova, M.S.1
Kondratov, K.A.2
Kornilova, E.S.3
-
53
-
-
33644864967
-
Ubiquitylation of leptin receptor OB-Ra regulates its clathrin-mediated endocytosis
-
Belouzard S, Rouille Y, (2006) Ubiquitylation of leptin receptor OB-Ra regulates its clathrin-mediated endocytosis. Embo J 25: 932-942.
-
(2006)
Embo J
, vol.25
, pp. 932-942
-
-
Belouzard, S.1
Rouille, Y.2
-
54
-
-
4344568740
-
Role of endogenous IL-10 in LPS-induced STAT3 activation and IL-1 receptor antagonist gene expression
-
Carl VS, Gautam JK, Comeau LD, Smith MF Jr, (2004) Role of endogenous IL-10 in LPS-induced STAT3 activation and IL-1 receptor antagonist gene expression. J Leukoc Biol 76: 735-742.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 735-742
-
-
Carl, V.S.1
Gautam, J.K.2
Comeau, L.D.3
Smith Jr., M.F.4
-
55
-
-
33646869503
-
Multisite Protein Kinase A and Glycogen Synthase Kinase 3beta Phosphorylation Leads to Gli3 Ubiquitination by SCF betaTrCP
-
Tempe D, Casas M, Karaz S, Blanchet-Tournier M-F, Concordet J-P, (2006) Multisite Protein Kinase A and Glycogen Synthase Kinase 3beta Phosphorylation Leads to Gli3 Ubiquitination by SCF betaTrCP. Mol Cell Biol 26: 4316-4326.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4316-4326
-
-
Tempe, D.1
Casas, M.2
Karaz, S.3
Blanchet-Tournier, M.-F.4
Concordet, J.-P.5
-
56
-
-
28444449828
-
Phosphorylation by Double-Time/CKIepsilon and CKIalpha Targets Cubitus Interruptus for Slimb/betaTRCP-Mediated Proteolytic Processing
-
Jia J, Zhang L, Zhang Q, Tong C, Wang B, et al. (2005) Phosphorylation by Double-Time/CKIepsilon and CKIalpha Targets Cubitus Interruptus for Slimb/betaTRCP-Mediated Proteolytic Processing. Developmental cell 9: 819-830.
-
(2005)
Developmental Cell
, vol.9
, pp. 819-830
-
-
Jia, J.1
Zhang, L.2
Zhang, Q.3
Tong, C.4
Wang, B.5
-
57
-
-
0033106369
-
Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels
-
Hicke L, (1999) Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels. Trends in Cell Biology 9: 107-112.
-
(1999)
Trends in Cell Biology
, vol.9
, pp. 107-112
-
-
Hicke, L.1
-
59
-
-
33947311208
-
Decoding ubiquitin sorting signals for clathrin-dependent endocytosis by CLASPs
-
Traub LM, Lukacs GL, (2007) Decoding ubiquitin sorting signals for clathrin-dependent endocytosis by CLASPs. Journal of Cell Science 120: 543-553.
-
(2007)
Journal of Cell Science
, vol.120
, pp. 543-553
-
-
Traub, L.M.1
Lukacs, G.L.2
-
60
-
-
36849091453
-
Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis
-
Kumar KG, Barriere H, Carbone CJ, Liu J, Swaminathan G, et al. (2007) Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis. J Cell Biol 179: 935-950.
-
(2007)
J Cell Biol
, vol.179
, pp. 935-950
-
-
Kumar, K.G.1
Barriere, H.2
Carbone, C.J.3
Liu, J.4
Swaminathan, G.5
-
61
-
-
77951757948
-
Trafficking and Degradation Associated with K48 and K63 Polyubiquitination
-
ErbB2
-
Marx C, Held JM, Gibson BW, Benz CC ErbB2, (2010) Trafficking and Degradation Associated with K48 and K63 Polyubiquitination. Cancer Research 70: 3709-3717.
-
(2010)
Cancer Research
, vol.70
, pp. 3709-3717
-
-
Marx, C.1
Held, J.M.2
Gibson, B.W.3
Benz, C.C.4
-
62
-
-
34547115036
-
The ubiquitin ligase SCF(betaTrCP) regulates the degradation of the growth hormone receptor
-
van Kerkhof P, Putters J, Strous GJ, (2007) The ubiquitin ligase SCF(betaTrCP) regulates the degradation of the growth hormone receptor. J Biol Chem 282: 20475-20483.
-
(2007)
J Biol Chem
, vol.282
, pp. 20475-20483
-
-
van Kerkhof, P.1
Putters, J.2
Strous, G.J.3
-
63
-
-
19444365121
-
Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives
-
Krause CD, Pestka S, (2005) Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives. Pharmacol Ther 106: 299-346.
-
(2005)
Pharmacol Ther
, vol.106
, pp. 299-346
-
-
Krause, C.D.1
Pestka, S.2
-
64
-
-
45749086679
-
The amphioxus genome and the evolution of the chordate karyotype
-
Putnam NH, Butts T, Ferrier DEK, Furlong RF, Hellsten U, et al. (2008) The amphioxus genome and the evolution of the chordate karyotype. Nature 453: 1064-1071.
-
(2008)
Nature
, vol.453
, pp. 1064-1071
-
-
Putnam, N.H.1
Butts, T.2
Ferrier, D.E.K.3
Furlong, R.F.4
Hellsten, U.5
-
65
-
-
9144250427
-
Comparative genomic analysis reveals independent expansion of a lineage-specific gene family in vertebrates: the class II cytokine receptors and their ligands in mammals and fish
-
Lutfalla G, Roest Crollius H, Stange-Thomann N, Jaillon O, Mogensen K, et al. (2003) Comparative genomic analysis reveals independent expansion of a lineage-specific gene family in vertebrates: the class II cytokine receptors and their ligands in mammals and fish. BMC Genomics 4: 29.
-
(2003)
BMC Genomics
, vol.4
, pp. 29
-
-
Lutfalla, G.1
Roest Crollius, H.2
Stange-Thomann, N.3
Jaillon, O.4
Mogensen, K.5
-
66
-
-
0033083158
-
Signal-induced ubiquitination of IkappaB by the F-box protein Slimb/b-TrCP
-
Spencer E, Jiang J, Chen ZJ, (1999) Signal-induced ubiquitination of IkappaB by the F-box protein Slimb/b-TrCP. Genes & Development 13: 284-294.
-
(1999)
Genes & Development
, vol.13
, pp. 284-294
-
-
Spencer, E.1
Jiang, J.2
Chen, Z.J.3
-
67
-
-
66749097742
-
Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy
-
Pearce C, Hayden RE, Bunce CM, Khanim FL, (2009) Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy. BMC Cell Biol 10: 31.
-
(2009)
BMC Cell Biol
, vol.10
, pp. 31
-
-
Pearce, C.1
Hayden, R.E.2
Bunce, C.M.3
Khanim, F.L.4
-
68
-
-
0033600604
-
The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation
-
Karin M, (1999) The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation. J Biol Chem 274: 27339-27342.
-
(1999)
J Biol Chem
, vol.274
, pp. 27339-27342
-
-
Karin, M.1
-
69
-
-
71949099545
-
Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling
-
Liu J, Carvalho LP, Bhattacharya S, Carbone CJ, Kumar KG, et al. (2009) Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling. Mol Cell Biol 29: 6401-6412.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 6401-6412
-
-
Liu, J.1
Carvalho, L.P.2
Bhattacharya, S.3
Carbone, C.J.4
Kumar, K.G.5
-
70
-
-
59749094883
-
Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1
-
Gruber SG, Luciani MG, Grundtner P, Zdanov A, Gasche C, (2008) Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1. European Journal of Immunology 38: 3365-3375.
-
(2008)
European Journal of Immunology
, vol.38
, pp. 3365-3375
-
-
Gruber, S.G.1
Luciani, M.G.2
Grundtner, P.3
Zdanov, A.4
Gasche, C.5
-
71
-
-
0037415720
-
The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression
-
Ragimbeau J, Dondi E, Alcover A, Eid P, Uze G, et al. (2003) The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression. EMBO J 22: 537-547.
-
(2003)
EMBO J
, vol.22
, pp. 537-547
-
-
Ragimbeau, J.1
Dondi, E.2
Alcover, A.3
Eid, P.4
Uze, G.5
|