Apple peel polyphenol extract protects against indomethacin-induced damage in Caco-2 cells by preventing mitochondrial Complex i inhibition

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 21, 2011, Pages 11501-11508

  Carrasco Pozo, Catalina ^a   Gotteland, Martin ^a   Speisky, Hernán ^a  

^a UNIVERSITY OF CHILE   (Chile)

Author keywords

apple polyphenols; indomethacin; mitochondrial complex I; superoxide radicals; xanthine oxidase

Indexed keywords

INDOMETHACIN; MITOCHONDRIAL COMPLEX; POLYPHENOLS; SUPEROXIDE RADICAL; XANTHINE OXIDASE;

CYTOTOXICITY; FRUITS; OXIDATION; OXIDATIVE STRESS; OXYGEN; PHENOLS;

MITOCHONDRIA;

APPLE POLYPHENOL EXTRACT; CHLOROGENIC ACID; FLAVONOID; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROTECTIVE AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TANNIN DERIVATIVE; XANTHINE OXIDASE;

ARTICLE; CELL STRAIN CACO 2; DOWN REGULATION; DRUG EFFECT; ENZYMOLOGY; HUMAN; LIPID PEROXIDATION; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CACO-2 CELLS; CHLOROGENIC ACID; DOWN-REGULATION; ELECTRON TRANSPORT COMPLEX I; FLAVONOIDS; HUMANS; INDOMETHACIN; LIPID PEROXIDATION; MITOCHONDRIA; NADPH OXIDASE; OXIDATIVE STRESS; PROTECTIVE AGENTS; SUPEROXIDES; TANNINS; XANTHINE OXIDASE;

MALUS X DOMESTICA;

EID: 80455162705     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf202621d     Document Type: Article

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