Apple polyphenol extracts prevent aspirin-induced damage to the rat gastric mucosa

British Journal of Nutrition

Volumn 100, Issue 6, 2008, Pages 1228-1236

  D'Argenio, Giuseppe ^a   Mazzone, Giovanna ^a   Tuccillo, Concetta ^b   Grandone, Ilenia ^a   Gravina, Antonietta G ^b   Graziani, Giulia ^a   Fogliano, Vincenzo ^a   Romano, Marco ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

Apple polyphenols; Aspirin; Gastric injury

Indexed keywords

ACETYLSALICYLIC ACID; APPLE EXTRACT; CYCLOOXYGENASE 2; ESOMEPRAZOLE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; MALONALDEHYDE; MESSENGER RNA; PLANT EXTRACT; POLYPHENOL DERIVATIVE; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APPLE; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG COMPETITION; DRUG MECHANISM; GENE EXPRESSION REGULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MONOTHERAPY; NONHUMAN; PRIMARY PREVENTION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH ACID SECRETION; STOMACH MUCOSA INJURY; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; BIOLOGICAL AVAILABILITY; CYCLOOXYGENASE 2; DRUG EVALUATION, PRECLINICAL; FLAVONOIDS; GASTRIC ACID; GASTRIC MUCOSA; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID PEROXIDATION; MALE; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; STOMACH ULCER; TRANSFORMING GROWTH FACTOR ALPHA;

MALUS X DOMESTICA; RATTUS;

EID: 56349118468     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114508988747     Document Type: Article

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