Identification of pyrido[1,2-α]pyrimidine-4-ones as new molecules improving the transcriptional functions of estrogen-related receptor α

Journal of Medicinal Chemistry

Volumn 54, Issue 21, 2011, Pages 7729-7733

  Peng, Lijie ^a,b   Gao, Xuefei ^a   Duan, Lei ^a   Ren, Xiaomei ^a,c   Wu, Donghai ^a   Ding, Ke ^a  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

2,8 DIPHENYL 4H PYRIDO[1,2 A]PYRIMIDIN 4 ONE; 8 CYCLOPROPYL 2 PHENYL 4H PYRIDO[1,2 A]PYRIMIDIN 4 ONE; 8 METHYL 2 PHENYL 4H PYRIDO[1,2 A]PYRIMIDIN 4 ONE; BETA TUBULIN; ESTROGEN RELATED RECEPTOR ALPHA; FATTY ACID; GLUCOSE; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; MESSENGER RNA; PYRIMIDINE DERIVATIVE; PYRUVATE DEHYDROGENASE KINASE 4; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL CELL; ARTICLE; BIOGENESIS; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; FATTY ACID TRANSPORT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GLUCOSE TRANSPORT; MITOCHONDRION; MOUSE; NONHUMAN;

ANIMALS; CELL LINE; ESTROGEN RECEPTOR ALPHA; FATTY ACIDS; GENES, REPORTER; GLUCOSE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LUCIFERASES; MICE; MUSCLE, SKELETAL; PYRIDINES; PYRIMIDINES; RNA, MESSENGER; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 80455144761     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200976s     Document Type: Article

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