Human ERRγ a third member of the estrogen receptor-related receptor (ERR) subfamily of orphan nuclear receptors: Tissue-specific isoforms are expressed during development and in the adult

Molecular Endocrinology

Volumn 14, Issue 3, 2000, Pages 382-392

  Heard, David J ^a,c   Norby, Peder L ^a   Holloway, Jim ^b   Vissing, Henrik ^a  

^a NOVO NORDISK A S   (Denmark)

^b ZYMOGENETICS INC   (United States)

^c Exonhit Therapeutics SA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; ESTRADIOL; ESTROGEN RECEPTOR RELATED RECEPTOR ALPHA; ESTROGEN RECEPTOR RELATED RECEPTOR BETA; MESSENGER RNA; UNCLASSIFIED DRUG; CELL RECEPTOR; FETOPROTEIN; HYBRID PROTEIN; ISOPROTEIN;

ADULT; ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN; FETUS; HUMAN; HUMAN TISSUE; KIDNEY; NUCLEOTIDE SEQUENCE; PANCREAS; PLACENTA; PRIORITY JOURNAL; PROTEIN DNA BINDING; TISSUE SPECIFICITY; TRANSACTIVATION; AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; BIOSYNTHESIS; CELL LINE; COMPARATIVE STUDY; EXPRESSED SEQUENCE TAG; GENE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; MOLECULAR GENETICS; MULTIGENE FAMILY; PHYSIOLOGY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ANIMALIA; EUKARYOTA;

ADULT; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; BASE SEQUENCE; CELL LINE; EXPRESSED SEQUENCE TAGS; FETAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES; HUMANS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; ORGAN SPECIFICITY; PROTEIN ISOFORMS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANS-ACTIVATION (GENETICS); TRANSFECTION;

EID: 0034335415     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.14.3.382     Document Type: Article

References (32)

1. Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life?
2. Transcription factors 3: Nuclear receptors
3. The nuclear receptor superfamily: The second decade
4. Steroid hormone receptors: Many actors in search of a plot
5. The RXR heterodimers and orphan receptors
6. Orphan nuclear receptors-the first eight years
7. Identification of a new class of steroid hormone receptors
8. Estrogen-related receptor, hERR1, modulates estrogen receptor-mediated response of human lactoferrin gene promoter
9. The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene
10. Estrogen-related receptor α1 functionally binds as a monomer to extended half-site sequences including ones contained within estrogenresponse elements
11. Two organochlorine pesticides, toxaphene and chlordane, are antagonists for estrogen-related receptor α-1 orphan receptor
12. Transcriptional activities of the orphan nuclear receptor ERR α (estrogen receptor-related receptor-α)
13. Transcriptional targets shared by estrogen receptor-related receptors (ERRs) and estrogen receptor (ER) α, but not by ERβ
14. SV40 early-to-late switch involves titration of cellular transcriptional repressors
15. Nuclear orphan receptor as a repressor of glucocorticoid receptor transcriptional activity
16. The ERR-1 orphan receptor is a transcriptional activator expressed during bone development
17. Expression of the estrogen-related receptor 1 (ERR-1) orphan receptor during mouse development
18. The mouse estrogen receptor-related orphan receptor alpha 1: Molecular cloning and estrogen responsiveness
19. Expression of a novel member of estrogen response element-binding nuclear receptors is restricted to the early stages of chorion formation during mouse embryogenesis
20. Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-β
21. Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR
22. Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type Ila at 1q41
23. SXR, a novel steroid and xenobiotic-sensing nuclear receptor
24. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
25. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction
26. Initiation of protein synthesis in eukaryotic cells
27. Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3
28. Basic local alignment search tool
29. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway
30. Human oestrogen receptor cDNA: Sequence, expression and homology to v-erb-A
31. GAL4 fusion vectors for expression in yeast or mammalian cells