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Volumn 344, Issue 11, 2011, Pages 726-734

Synthesis and biological evaluation of novel homocamptothecins conjugating with dihydropyrimidine derivatives as potent topoisomerase i inhibitors

(13) Zhu, Lingjian a Cheng, Pengfei a Lei, Ning b Yao, Jianzhong a Sheng, Chunquan a Zhuang, Chunlin a Guo, Wei a Liu, Wenfeng a Zhang, Yongqiang a Dong, Guoqiang a Wang, Shengzhang a Miao, Zhenyuan a Zhang, Wannian a

a SECOND MILITARY MEDICAL UNIVERSITY (China)

b Lian Yun Gang JARI Pharmaceutical Co Ltd (China)

Author keywords

Biological activity; Camptothecin; Dihydropyrimidine; Homocamptothecin

Indexed keywords

7 FORMYLHOMOCAMPTOTHECIN; DIHYDROPYRIMIDINE DERIVATIVE; DNA TOPOISOMERASE INHIBITOR; HOMOCAMPTOTHECIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL PROLIFERATION; DRUG DESIGN; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CELL LINE, TUMOR; CELL PROLIFERATION; DNA TOPOISOMERASES, TYPE I; HCT116 CELLS; HUMANS; NEOPLASMS; PYRIMIDINES; TOPOISOMERASE I INHIBITORS;

EID: 80355137292 PISSN: 03656233 EISSN: 15214184 Source Type: Journal
DOI: 10.1002/ardp.201000402 Document Type: Article

Times cited : (28)

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