Synthesis and differential antiproliferative activity of Biginelli compounds against cancer cell lines: Monastrol, oxo-monastrol and oxygenated analogues

Bioorganic Chemistry

Volumn 34, Issue 4, 2006, Pages 173-182

  Russowsky, Dennis ^a   Canto, Rômulo F S ^a   Sanches, Sergio A A ^a   D'Oca, Marcelo G M ^a   de Fátima, Ângelo ^b   Pilli, Ronaldo A ^b   Kohn, Luciana K ^b   Antônio, Márcia A ^b   de Carvalho, João Ernesto ^b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Antiproliferative; Cancer; Dihydropyrimidinones; Mitotic kinesin Eg5; Monastrol

Indexed keywords

AGENTS AFFECTING CELL DIVISION; ANTINEOPLASTIC AGENT; DOXORUBICIN; MONASTROL; OXOMONASTROL; PYRIMIDINE DERIVATIVE; SULFUR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; OXYGEN; PYRIMIDINES; THIONES;

EID: 33745752826     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2006.04.003     Document Type: Article

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